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Select item 108351291.

Amino acid and protein specificity of protein fatty acylation in C. elegans

Bingsen Zhang, Yan Yu, Bennett W. Fox, Yinong Liu, Venkatesh P. Thirumalaikumar, Aleksandra Skirycz, Hening Lin, Frank C. Schroeder

Proc Natl Acad Sci U S A. 2024 Jan 30; 121(5): e2307515121. Published online 2024 Jan 22. doi: 10.1073/pnas.2307515121

PMCID:: PMC10835129

Abstract Article PDF–1.4M

Select item 108029522.

Characterization of the intracellular neurexin interactome by in vivo proximity ligation suggests its involvement in presynaptic actin assembly

Marcos Schaan Profes, Araven Tiroumalechetty, Neel Patel, Stephanie S. Lauar, Simone Sidoli, Peri T. Kurshan

PLoS Biol. 2024 Jan; 22(1): e3002466. Published online 2024 Jan 22. doi: 10.1371/journal.pbio.3002466

PMCID:: PMC10802952

Abstract Article PDF–2.7M

Select item 106564263.

Feedforward regulatory logic controls the specification-to-differentiation transition and terminal cell fate during Caenorhabditis elegans endoderm development

Chee Kiang Ewe, Erica M. Sommermann, Josh Kenchel, Sagen E. Flowers, Morris F. Maduro, Pradeep M. Joshi, Joel H. Rothman

Development. 2022 Jun 15; 149(12): dev200337. Published online 2022 Jun 27. doi: 10.1242/dev.200337

PMCID:: PMC10656426

Abstract Article

Select item 101591684.

Transcriptomics of ivermectin response in Caenorhabditis elegans: Integrating abamectin quantitative trait loci and comparison to the Ivermectin-exposed DA1316 strain

Faruk Dube, Andrea Hinas, Nicolas Delhomme, Magnus Åbrink, Staffan Svärd, Eva Tydén

PLoS One. 2023; 18(5): e0285262. Published online 2023 May 4. doi: 10.1371/journal.pone.0285262

PMCID:: PMC10159168

Abstract Article PDF–1.9M

Select item 98854405.

Intracellular lipid surveillance by small G protein geranylgeranylation

Abigail Watterson, Lexus Tatge, Naureen Wajahat, Sonja L. B. Arneaud, Rene Solano Fonseca, Shaghayegh T. Beheshti, Patrick Metang, Melina Mihelakis, Kielen R. Zuurbier, Chase D. Corley, Ishmael Dehghan, Jeffrey G. McDonald, Peter M. Douglas

Nature. Author manuscript; available in PMC 2023 Jan 30.

Published in final edited form as: Nature. 2022 May; 605(7911): 736–740. Published online 2022 May 18. doi: 10.1038/s41586-022-04729-7

PMCID:: PMC9885440

Abstract Article PDF–4.2M

Select item 97499066.

2-hydroxyisobutyric acid (2-HIBA) modulates ageing and fat deposition in Caenorhabditis elegans

Emily Schifano, Giorgia Conta, Adele Preziosi, Carino Ferrante, Giovanni Batignani, Patrizia Mancini, Alberta Tomassini, Fabio Sciubba, Tullio Scopigno, Daniela Uccelletti, Alfredo Miccheli

Front Mol Biosci. 2022; 9: 986022. Published online 2022 Nov 23. doi: 10.3389/fmolb.2022.986022

PMCID:: PMC9749906

Abstract Article PDF–3.1M

Select item 96420767.

Loss of heat shock factor initiates intracellular lipid surveillance by actin destabilization

Abigail Watterson, Sonja L.B. Arneaud, Naureen Wajahat, Jordan M. Wall, Lexus Tatge, Shaghayegh T. Beheshti, Melina Mihelakis, Nicholas Y. Cheatwood, Jacob McClendon, Atossa Ghorashi, Ishmael Dehghan, Chase D. Corley, Jeffrey G. McDonald, Peter M. Douglas

Cell Rep. Author manuscript; available in PMC 2022 Nov 8.

Published in final edited form as: Cell Rep. 2022 Oct 18; 41(3): 111493. doi: 10.1016/j.celrep.2022.111493

PMCID:: PMC9642076

Abstract Article PDF–1.6M

Select item 95563528.

Determining Toxic Potencies of Water-Soluble Contaminants in Wastewater Influents and Effluent Using Gene Expression Profiling in C. elegans as a Bioanalytical Tool

Antoine Karengera, Ilse Verburg, Mark G. Sterken, Joost A. G. Riksen, Albertinka J. Murk, Inez J. T. Dinkla

Arch Environ Contam Toxicol. 2022; 83(3): 284–294. Published online 2022 Oct 3. doi: 10.1007/s00244-022-00959-y

PMCID:: PMC9556352

Abstract Article PDF–1.4M

Select item 91299229.

SMGL-1/NBAS acts as a RAB-8 GEF to regulate unconventional protein secretion

Xianghong Wang, Xinxin Li, Junkai Wang, Jiabin Wang, Can Hu, Jia Zeng, Anbing Shi, Long Lin

J Cell Biol. 2022 Jul 4; 221(7): e202111125. Published online 2022 May 23. doi: 10.1083/jcb.202111125

PMCID:: PMC9129922

Abstract Article PDF–8.5M

Select item 870581710.

Exposure of Caenorhabditis elegans to Dietary Nε-Carboxymethyllysine Emphasizes Endocytosis as a New Route for Intestinal Absorption of Advanced Glycation End Products

Constance Dubois, Rachel Litke, Stéphane Rianha, Charles Paul-Constant, Jean-Marc Lo Guidice, Solenne Taront, Frédéric J. Tessier, Eric Boulanger, Chantal Fradin

Nutrients. 2021 Dec; 13(12): 4398. Published online 2021 Dec 8. doi: 10.3390/nu13124398

PMCID:: PMC8705817

Abstract Article PDF–21M

Select item 843352311.

Stress increases in exopher-mediated neuronal extrusion require lipid biosynthesis, FGF, and EGF RAS/MAPK signaling

Jason F. Cooper, Ryan J. Guasp, Meghan Lee Arnold, Barth D. Grant, Monica Driscoll

Proc Natl Acad Sci U S A. 2021 Sep 7; 118(36): e2101410118. Published online 2021 Sep 2. doi: 10.1073/pnas.2101410118

PMCID:: PMC8433523

Abstract Article PDF–1.4M

Select item 818700812.

Genes implicated in Caenorhabditis elegans and human health regulate stress resistance and physical abilities in aged Caenorhabditis elegans

Jessica Dysarz, Georg Fuellen, Steffen Möller, Walter Luyten, Christian Schmitz-Linneweber, Nadine Saul

Biol Lett. 2021 Jun; 17(6): 20200916. Published online June 9, 2021. doi: 10.1098/rsbl.2020.0916

PMCID:: PMC8187008

Abstract Article PDF–715K

Select item 799517613.

EPIC: Software Toolkit for Elution Profile-Based Inference of Protein Complexes

Lucas ZhongMing Hu, Florian Goebels, June H. Tan, Eric Wolf, Uros Kuzmanov, Cuihong Wan, Sadhna Phanse, Changjiang Xu, Mike Schertzberg, Andrew G. Fraser, Gary D. Bader, Andrew Emili

Nat Methods. Author manuscript; available in PMC 2021 Mar 26.

Published in final edited form as: Nat Methods. 2019 Aug; 16(8): 737–742. Published online 2019 Jul 15. doi: 10.1038/s41592-019-0461-4

PMCID:: PMC7995176

Abstract Article PDF–1.0M

Select item 785574414.

Coordinate Regulation of Ribosome and tRNA Biogenesis Controls Hypoxic Injury and Translation

Omar A Itani, Xuefei Zhong, Xiaoting Tang, Barbara A. Scott, Jun Yi Yan, Stephane Flibotte, Yiting Lim, Andrew C. Hsieh, James E. Bruce, Marc Van Gilst, C. Michael Crowder

Curr Biol. Author manuscript; available in PMC 2022 Jan 11.

Published in final edited form as: Curr Biol. 2021 Jan 11; 31(1): 128–137.e5. Published online 2020 Nov 5. doi: 10.1016/j.cub.2020.10.001

Correction in:: Curr Biol. 2022 Dec 19; 32(24): 5433.

PMCID:: PMC7855744

Abstract Article PDF–738K

Select item 737784815.

Healthspan pathway maps in C. elegans and humans highlight transcription, proliferation/biosynthesis and lipids

Steffen Möller, Nadine Saul, Alan A. Cohen, Rüdiger Köhling, Sina Sender, Hugo Murua Escobar, Christian Junghanss, Francesca Cirulli, Alessandra Berry, Peter Antal, Priit Adler, Jaak Vilo, Michele Boiani, Ludger Jansen, Dirk Repsilber, Hans Jörgen Grabe, Stephan Struckmann, Israel Barrantes, Mohamed Hamed, Brecht Wouters, Liliane Schoofs, Walter Luyten, Georg Fuellen

Aging (Albany NY) 2020 Jul 15; 12(13): 12534–12581. Published online 2020 Jul 7. doi: 10.18632/aging.103514