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Items: 1 to 20 of 39

1.
Inhibiting von Hippel‒Lindau protein-mediated Dishevelled ubiquitination protects against experimental parkinsonism
Jie Shen, Qian Zha, Qian-hua Yang, Yue-qian Zhou, Xiao Liang, Ying-jie Chen, Gui-xia Qi, Xiao-jin Zhang, Wen-bing Yao, Xiang-dong Gao, Song Chen
Acta Pharmacol Sin. 2023 May; 44(5): 940–953. Published online 2022 Nov 10. doi: 10.1038/s41401-022-01014-1
PMCID:
PMC10104824
AbstractArticlePDF–6.3M
2.
SCD5 Regulation by VHL Affects Cell Proliferation and Lipid Homeostasis in ccRCC
Athina Ganner, Antonia Philipp, Simon Lagies, Laura Wingendorf, Lu Wang, Felicitas Pilz, Thomas Welte, Kelli Grand, Soeren S. Lienkamp, Marinella Klein, Bernd Kammerer, Ian J. Frew, Gerd Walz, Elke Neumann-Haefelin
Cells. 2023 Mar; 12(6): 835. Published online 2023 Mar 8. doi: 10.3390/cells12060835
PMCID:
PMC10047146
AbstractArticlePDF–1.8M
3.
Co-opted genes of algal origin protect C. elegans against cyanogenic toxins
Bingying Wang, Taruna Pandey, Yong Long, Sofia E. Delgado-Rodriguez, Matthew D. Daugherty, Dengke K. Ma
Curr Biol. Author manuscript; available in PMC 2023 Nov 21.
Published in final edited form as: Curr Biol. 2022 Nov 21; 32(22): 4941–4948.e3. Published online 2022 Oct 11. doi: 10.1016/j.cub.2022.09.041
PMCID:
PMC9691542
AbstractArticlePDF–1.9M
4.
The hypoxia response pathway promotes PEP carboxykinase and gluconeogenesis in C. elegans
Mehul Vora, Stephanie M. Pyonteck, Tatiana Popovitchenko, Tarmie L. Matlack, Aparna Prashar, Nanci S. Kane, John Favate, Premal Shah, Christopher Rongo
Nat Commun. 2022; 13: 6168. Published online 2022 Oct 18. doi: 10.1038/s41467-022-33849-x
PMCID:
PMC9579151
AbstractArticlePDF–2.9M
5.
Dietary-derived vitamin B12 protects Caenorhabditis elegans from thiol-reducing agents
Alan D. Winter, Elissa Tjahjono, Leonardo J. Beltrán, Iain L. Johnstone, Neil J. Bulleid, Antony P. Page
BMC Biol. 2022; 20: 228. Published online 2022 Oct 8. doi: 10.1186/s12915-022-01415-y
PMCID:
PMC9548181
AbstractArticlePDF–2.5M
6.
Gene regulatory network inference in long-lived C. elegans reveals modular properties that are predictive of novel aging genes
Manusnan Suriyalaksh, Celia Raimondi, Abraham Mains, Anne Segonds-Pichon, Shahzabe Mukhtar, Sharlene Murdoch, Rebeca Aldunate, Felix Krueger, Roger Guimerà, Simon Andrews, Marta Sales-Pardo, Olivia Casanueva
iScience. 2022 Jan 21; 25(1): 103663. Published online 2021 Dec 20. doi: 10.1016/j.isci.2021.103663
PMCID:
PMC8753122
AbstractArticlePDF–4.6M
7.
VHL suppresses RAPTOR and inhibits mTORC1 signaling in clear cell renal cell carcinoma
Athina Ganner, Christina Gehrke, Marinella Klein, Lena Thegtmeier, Tanja Matulenski, Laura Wingendorf, Lu Wang, Felicitas Pilz, Lars Greidl, Lisa Meid, Fruzsina Kotsis, Gerd Walz, Ian J. Frew, Elke Neumann-Haefelin
Sci Rep. 2021; 11: 14827. Published online 2021 Jul 21. doi: 10.1038/s41598-021-94132-5
PMCID:
PMC8295262
AbstractArticlePDF–2.4M
8.
Hypoxic response regulators RHY-1 and EGL-9/PHD promote longevity through a VHL-1-independent transcriptional response
Joseph C.P. Kruempel, Hillary A. Miller, Megan L. Schaller, Abrielle Fretz, Marshall Howington, Marjana Sarker, Shijiao Huang, Scott F. Leiser
GeroScience. 2020 Dec; 42(6): 1621–1633. Published online 2020 May 12. doi: 10.1007/s11357-020-00194-0
PMCID:
PMC7732922
AbstractArticlePDF–1.2M
9.
HIF-1 Has a Central Role in Caenorhabditis elegans Organismal Response to Selenium
Laura Romanelli-Credrez, Maria Doitsidou, Mark J. Alkema, Gustavo Salinas
Front Genet. 2020; 11: 63. Published online 2020 Feb 25. doi: 10.3389/fgene.2020.00063
PMCID:
PMC7052493
AbstractArticlePDF–1.8M
10.
The stress-responsive gene GDPGP1/mcp-1 regulates neuronal glycogen metabolism and survival
Alexander Schulz, Yuichi Sekine, Motunrayo J. Oyeyemi, Alexander J. Abrams, Manasa Basavaraju, Sung Min Han, Marco Groth, Helen Morrison, Stephen M. Strittmatter, Marc Hammarlund
J Cell Biol. 2020 Feb 3; 219(2): e201807127. Published online 2020 Jan 22. doi: 10.1083/jcb.201807127
PMCID:
PMC7041677
AbstractArticlePDF–2.5M
11.
Activation of Hypoxia-Inducible Factor Signaling Modulates the RNA Protein Interactome in Caenorhabditis elegans
Reza Esmaillie, Michael Ignarski, Katrin Bohl, Tim Krüger, Daniyal Ahmad, Lisa Seufert, Bernhard Schermer, Thomas Benzing, Roman-Ulrich Müller, Francesca Fabretti
iScience. 2019 Dec 20; 22: 466–476. Published online 2019 Nov 27. doi: 10.1016/j.isci.2019.11.039
PMCID:
PMC6926210
AbstractArticlePDF–3.9M
12.
Ferritin is regulated by a neuro-intestinal axis in the nematode Caenorhabditis elegans
Leonor Romero-Afrima, Veronica Zelmanovich, Zohar Abergel, Binyamin Zuckerman, Maayan Shaked, Rachel Abergel, Leonid Livshits, Yoav Smith, Einav Gross
Redox Biol. 2020 Jan; 28: 101359. Published online 2019 Oct 25. doi: 10.1016/j.redox.2019.101359
PMCID:
PMC6920132
AbstractArticlePDF–2.2M
13.
VHL-1 inactivation and mitochondrial antioxidants rescue C. elegans dopaminergic neurodegeneration
Song Chen, Shuo Luo, Zhe Zhang, Dengke K. Ma
Protein Cell. 2019 Aug; 10(8): 610–614. Published online 2019 Apr 3. doi: 10.1007/s13238-019-0621-4
PMCID:
PMC6626599
ArticlePDF–2.1M
14.
The hypoxia-response pathway modulates RAS/MAPK–mediated cell fate decisions in Caenorhabditis elegans
Sabrina Maxeiner, Judith Grolleman, Tobias Schmid, Jan Kammenga, Alex Hajnal
Life Sci Alliance. 2019 Jun; 2(3): e201800255. Published online 2019 May 24. doi: 10.26508/lsa.201800255
PMCID:
PMC6536719
AbstractArticlePDF–2.2M
15.
Hypoxia Restrains Lipid Utilization via Protein Kinase A and Adipose Triglyceride Lipase Downregulation through Hypoxia-Inducible Factor
Ji Seul Han, Jung Hyun Lee, Jinuk Kong, Yul Ji, Jiwon Kim, Sung Sik Choe, Jae Bum Kim
Mol Cell Biol. 2019 Jan 15; 39(2): e00390-18. Prepublished online 2018 Nov 5. Published online 2019 Jan 3. doi: 10.1128/MCB.00390-18
PMCID:
PMC6321877
AbstractArticlePDF–5.4M
16.
The Energy Maintenance Theory of Aging: maintaining energy metabolism to allow longevity
Snehal N. Chaudhari, Edward T. Kipreos
Bioessays. Author manuscript; available in PMC 2019 Aug 1.
Published in final edited form as: Bioessays. 2018 Aug; 40(8): e1800005. Published online 2018 Jun 14. doi: 10.1002/bies.201800005
PMCID:
PMC6314662
AbstractArticlePDF–431K
17.
An Elongin-Cullin-SOCS-box Complex Regulates Stress-induced Serotonergic Neuromodulation
Xicotencatl Gracida, Michael F. Dion, Gareth Harris, Yun Zhang, John A. Calarco
Cell Rep. Author manuscript; available in PMC 2018 Dec 6.
Published in final edited form as: Cell Rep. 2017 Dec 12; 21(11): 3089–3101. doi: 10.1016/j.celrep.2017.11.042
PMCID:
PMC6283282
AbstractArticlePDF–858K
18.
OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes
Woojin Kim, Ryan S. Underwood, Iva Greenwald, Daniel D. Shaye
Genetics. 2018 Oct; 210(2): 445–461. Published online 2018 Aug 17. doi: 10.1534/genetics.118.301307
PMCID:
PMC6216590
AbstractArticlePDF–1.4M
19.
Genetic interaction with temperature is an important determinant of nematode longevity
Hillary Miller, Marissa Fletcher, Melissa Primitivo, Alison Leonard, George L. Sutphin, Nicholas Rintala, Matt Kaeberlein, Scott F. Leiser
Aging Cell. 2017 Dec; 16(6): 1425–1429. Published online 2017 Sep 21. doi: 10.1111/acel.12658
PMCID:
PMC5676069
AbstractArticlePDF–884K
20.
Ubiquitin-mediated pathways in C. elegans.
Edward T Kipreos
WormBook. 2005 : 1–24. Published online 2005 Dec 1. doi: 10.1895/wormbook.1.36.1
PMCID:
PMC4781597
AbstractArticle

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