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Select item 109920961.

Polymorphism of formyl peptide receptor 1 (FPR1) reduces the therapeutic efficiency and antitumor immunity after neoadjuvant chemoradiotherapy (CCRT) treatment in locally advanced rectal cancer

Shu-Fen Chiang, Kevin Chih-Yang Huang, William Tzu-Liang Chen, Tsung-Wei Chen, Tao-Wei Ke, K. S. Clifford Chao

Cancer Immunol Immunother. 2021 Oct; 70(10): 2937–2950. Published online 2021 Mar 13. doi: 10.1007/s00262-021-02894-8

PMCID:: PMC10992096

Abstract Article PDF–3.3M

Select item 100380222.

Rs867228 in FPR1 accelerates the manifestation of luminal B breast cancer

Vincent Carbonnier, Julie Le Naour, Thomas Bachelot, Erika Vacchelli, Fabrice André, Suzette Delaloge, Guido Kroemer

Oncoimmunology. 2023; 12(1): 2189823. Published online 2023 Mar 21. doi: 10.1080/2162402X.2023.2189823

PMCID:: PMC10038022

Abstract Article PDF–1.4M

Select item 99817203.

Formyl peptide receptor 2 is an emerging modulator of inflammation in the liver

Chanbin Lee, Jinsol Han, Youngmi Jung

Exp Mol Med. 2023 Feb; 55(2): 325–332. Published online 2023 Feb 7. doi: 10.1038/s12276-023-00941-1

PMCID:: PMC9981720

Abstract Article PDF–1.1M

Select item 96944884.

Amyloid beta and its naturally occurring N-terminal variants are potent activators of human and mouse formyl peptide receptor 1

Lukas Busch, Zukaa al Taleb, Yu-Liang Tsai, Vu Thu Thuy Nguyen, Qi Lu, Christopher V. Synatschke, Kristina Endres, Bernd Bufe

J Biol Chem. 2022 Dec; 298(12): 102642. Published online 2022 Oct 27. doi: 10.1016/j.jbc.2022.102642

PMCID:: PMC9694488

Abstract Article PDF–3.7M

Select item 93514945.

Agonist concentration–dependent changes in FPR1 conformation lead to biased signaling for selective activation of phagocyte functions

Junlin Wang, Richard D. Ye

Proc Natl Acad Sci U S A. 2022 Aug 2; 119(31): e2201249119. Published online 2022 Jul 25. doi: 10.1073/pnas.2201249119

PMCID:: PMC9351494

Abstract Article PDF–2.2M

Select item 89853136.

Breast cancer metastasis to brain results in recruitment and activation of microglia through annexin-A1/formyl peptide receptor signaling

Sok Lin Foo, Karishma Sachaphibulkij, Corinne L. Y. Lee, Gracemary L. R. Yap, Jianzhou Cui, Thiruma Arumugam, Lina H. K. Lim

Breast Cancer Res. 2022; 24: 25. Published online 2022 Apr 5. doi: 10.1186/s13058-022-01514-2

PMCID:: PMC8985313

Abstract Article PDF–3.8M

Select item 88814697.

Molecular recognition of formylpeptides and diverse agonists by the formylpeptide receptors FPR1 and FPR2

Youwen Zhuang, Lei Wang, Jia Guo, Dapeng Sun, Yue Wang, Weiyi Liu, H. Eric Xu, Cheng Zhang

Nat Commun. 2022; 13: 1054. Published online 2022 Feb 25. doi: 10.1038/s41467-022-28586-0

PMCID:: PMC8881469

Abstract Article PDF–3.3M

Select item 84609918.

The Two Formyl Peptide Receptors Differently Regulate GPR84-Mediated Neutrophil NADPH Oxidase Activity

Jonas Mårtensson, Martina Sundqvist, Asmita Manandhar, Loukas Ieremias, Linjie Zhang, Trond Ulven, Xin Xie, Lena Björkman, Huamei Forsman

J Innate Immun. 2021 Sep; 13(4): 242–256. Published online 2021 Mar 31. doi: 10.1159/000514887

Correction in:: J Innate Immun. 2021 Sep; 13(5): 319.

PMCID:: PMC8460991

Abstract Article PDF–519K

Select item 84292689.

Association of Fpr1 Gene Expression with Osteogenesis and Adipogenesis of Adipose Derived Stem Cells

Wan’an Xiao, Quang Le, Di Zhu, Abhijit Dighe, Quanjun Cui, Xinlin Yang

Biochem Biophys Res Commun. Author manuscript; available in PMC 2022 Oct 15.

Published in final edited form as: Biochem Biophys Res Commun. 2021 Oct 15; 574: 33–38. Published online 2021 Aug 19. doi: 10.1016/j.bbrc.2021.08.044

PMCID:: PMC8429268

Abstract Article PDF–864K

Select item 816503010.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 812817511.

An independent predictor of poor prognosis in locally advanced rectal cancer: rs867228 in formyl peptide receptor 1 (FPR1)

Shu-Fen Chiang, Kevin Chih-Yang Huang, William Tzu-Liang Chen, Tsung-Wei Chen, Tao-Wei Ke, K. S. Clifford Chao

Oncoimmunology. 2021; 10(1): 1926074. Published online 2021 May 14. doi: 10.1080/2162402X.2021.1926074

PMCID:: PMC8128175

Abstract Article PDF–602K

Select item 807127412.

Mitocryptide-2: Identification of Its Minimum Structure for Specific Activation of FPR2–Possible Receptor Switching from FPR2 to FPR1 by Its Physiological C-terminal Cleavages

Takayuki Marutani, Kodai Nishino, Tomoyuki Miyaji, Keisuke Kamada, Koji Ohura, Yoshiaki Kiso, Hidehito Mukai

Int J Mol Sci. 2021 Apr; 22(8): 4084. Published online 2021 Apr 15. doi: 10.3390/ijms22084084

PMCID:: PMC8071274

Abstract Article PDF–4.6M

Select item 780111913.

A major genetic accelerator of cancer diagnosis: rs867228 in FPR1

Zsofia Sztupinszki, Julie Le Naour, Erika Vacchelli, Pierre Laurent-Puig, Suzette Delaloge, Zoltan Szallasi, Guido Kroemer

Oncoimmunology. 2021; 10(1): 1859064. Published online 2021 Jan 6. doi: 10.1080/2162402X.2020.1859064

PMCID:: PMC7801119

Article PDF–496K

Select item 773404214.

No impact of cancer and plague-relevant FPR1 polymorphisms on COVID-19

Adriana Petrazzuolo, Julie Le Naour, Erika Vacchelli, Pascale Gaussem, Syrine Ellouze, Georges Jourdi, Eric Solary, Michaela Fontenay, David M. Smadja, Guido Kroemer

Oncoimmunology. 2020; 9(1): 1857112. Published online 2020 Dec 8. doi: 10.1080/2162402X.2020.1857112

PMCID:: PMC7734042

Abstract Article PDF–377K

Select item 729129915.

Annexin A1/Formyl Peptide Receptor Pathway Controls Uterine Receptivity to the Blastocyst

Cristina B. Hebeda, Silvana Sandri, Cláudia M. Benis, Marina de Paula-Silva, Rodrigo A. Loiola, Chris Reutelingsperger, Mauro Perretti, Sandra H. P. Farsky

Cells. 2020 May; 9(5): 1188. Published online 2020 May 11. doi: 10.3390/cells9051188

PMCID:: PMC7291299

Abstract Article PDF–3.0M

Select item 722660216.

Exploring Biased Agonism at FPR1 as a Means to Encode Danger Sensing

Jieny Gröper, Gabriele M. König, Evi Kostenis, Volker Gerke, Carsten A. Raabe, Ursula Rescher

Cells. 2020 Apr; 9(4): 1054. Published online 2020 Apr 23. doi: 10.3390/cells9041054

PMCID:: PMC7226602

Abstract Article PDF–4.2M

Select item 719980917.

The ambiguous role of FPR1 in immunity and inflammation

Erika Vacchelli, Julie Le Naour, Guido Kroemer

Oncoimmunology. 2020; 9(1): 1760061. Published online 2020 Apr 30. doi: 10.1080/2162402X.2020.1760061

PMCID:: PMC7199809

Article PDF–759K

Select item 710115218.

FPR-1 is an important regulator of neutrophil recruitment and a tissue-specific driver of pulmonary fibrosis

Jack Leslie, Ben J.M. Millar, Alicia del Carpio Pons, Rachel A. Burgoyne, Joseph D. Frost, Ben S. Barksby, Saimir Luli, Jon Scott, A. John Simpson, Jack Gauldie, Lynne A. Murray, Donna K. Finch, Alan M. Carruthers, John Ferguson, Matthew A. Sleeman, David Rider, Rachel Howarth, Christopher Fox, Fiona Oakley, Andrew J. Fisher, Derek A. Mann, Lee A. Borthwick

JCI Insight. 2020 Feb 27; 5(4): e125937. Published online 2020 Feb 27. doi: 10.1172/jci.insight.125937

PMCID:: PMC7101152

Abstract Article PDF–22M

Select item 683917419.

Targeting the Formyl Peptide Receptor type 1 to prevent the adhesion of ovarian cancer cells onto mesothelium and subsequent invasion

Michele Minopoli, Giovanni Botti, Vincenzo Gigantino, Concetta Ragone, Sabrina Sarno, Maria Letizia Motti, Giosuè Scognamiglio, Stefano Greggi, Cono Scaffa, Maria Serena Roca, Maria Patrizia Stoppelli, Gennaro Ciliberto, Nunzia Simona Losito, Maria Vincenza Carriero

J Exp Clin Cancer Res. 2019; 38: 459. Published online 2019 Nov 8. doi: 10.1186/s13046-019-1465-8

PMCID:: PMC6839174

Abstract Article PDF–2.9M

Select item 677669120.

FPR1 is the plague receptor on host immune cells

Patrick Osei-Owusu, Thomas M. Charlton, Hwan Keun Kim, Dominique Missiakas, Olaf Schneewind

Nature. Author manuscript; available in PMC 2020 Mar 18.

Published in final edited form as: Nature. 2019 Oct; 574(7776): 57–62. Published online 2019 Sep 18. doi: 10.1038/s41586-019-1570-z

PMCID:: PMC6776691

Abstract Article PDF–4.5M

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