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Select item 79387701.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 66927702.

Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics

Joel D. Federspiel, Todd M. Greco, Krystal K. Lum, Ileana M. Cristea

Mol Cell Proteomics. 2019 Aug 9; 18(8 Suppl 1): S92–S113. Published online 2019 Apr 30. doi: 10.1074/mcp.RA118.001253

PMCID:: PMC6692770

Abstract Article PDF–7.7M

Select item 64059023.

Iws1 and Spt6 Regulate Trimethylation of Histone H3 on Lysine 36 through Akt Signaling and are Essential for Mouse Embryonic Genome Activation

Reza K. Oqani, Tao Lin, Jae Eun Lee, Jeong Won Kang, Hyun Young Shin, Dong Il Jin

Sci Rep. 2019; 9: 3831. Published online 2019 Mar 7. doi: 10.1038/s41598-019-40358-3

PMCID:: PMC6405902

Abstract Article PDF–2.5M

Select item 61353764.

Genetic ablation of interacting with Spt6 (Iws1) causes early embryonic lethality

Arturo Orlacchio, Aaron E. Stark, Claudia Foray, Foued Amari, Tyler Sheetz, Erika Reese, Anna Tessari, Krista La Perle, Dario Palmieri, Philip N. Tsichlis, Vincenzo Coppola

PLoS One. 2018; 13(9): e0201030. Published online 2018 Sep 12. doi: 10.1371/journal.pone.0201030

PMCID:: PMC6135376

Abstract Article PDF–8.7M

Select item 56597635.

The Elongation Factor Spt6 Maintains ESC Pluripotency by Controlling Super-Enhancers and Counteracting Polycomb Proteins

A. Hongjun Wang, Aster H. Juan, Kyung Dae Ko, Pei-Fang Tsai, Hossein Zare, Stefania Dell’Orso, Vittorio Sartorelli

Mol Cell. Author manuscript; available in PMC 2018 Oct 19.

Published in final edited form as: Mol Cell. 2017 Oct 19; 68(2): 398–413.e6. Published online 2017 Oct 12. doi: 10.1016/j.molcel.2017.09.016

PMCID:: PMC5659763

Abstract Article PDF–2.3M

Select item 51166446.

Towards Functional Annotation of the Preimplantation Transcriptome: An RNAi Screen in Mammalian Embryos

Wei Cui, Xiangpeng Dai, Chelsea Marcho, Zhengbin Han, Kun Zhang, Kimberly D. Tremblay, Jesse Mager

Sci Rep. 2016; 6: 37396. Published online 2016 Nov 21. doi: 10.1038/srep37396

PMCID:: PMC5116644

Abstract Article PDF–2.1M

Select item 45524937.

Venus trap in the mouse embryo reveals distinct molecular dynamics underlying specification of first embryonic lineages

Jens-Erik Dietrich, Laura Panavaite, Stefan Gunther, Sebastian Wennekamp, Anna C Groner, Anton Pigge, Stefanie Salvenmoser, Didier Trono, Lars Hufnagel, Takashi Hiiragi

EMBO Rep. 2015 Aug; 16(8): 1005–1021. Published online 2015 Jul 3. doi: 10.15252/embr.201540162

PMCID:: PMC4552493

Abstract Article PDF–2.7M

Select item 40734948.

The Central Role of EED in the Orchestration of Polycomb Group Complexes

Qi Cao, Xiaoju Wang, Meng Zhao, Rendong Yang, Rohit Malik, Yuanyuan Qiao, Anton Poliakov, Anastasia K. Yocum, Yong Li, Wei Chen, Xuhong Cao, Xia Jiang, Arun Dahiya, Clair Harris, Felix Y. Feng, Sundeep Kalantry, Zhaohui S. Qin, Saravana M. Dhanasekaran, Arul M. Chinnaiyan

Nat Commun. Author manuscript; available in PMC 2014 Jul 24.

Published in final edited form as: Nat Commun. 2014; 5: 3127. doi: 10.1038/ncomms4127

PMCID:: PMC4073494

Abstract Article PDF–2.1M

Select item 37461989.

A direct physical interaction between Nanog and Sox2 regulates embryonic stem cell self-renewal

Alessia Gagliardi, Nicholas P Mullin, Zi Ying Tan, Douglas Colby, Anastasia I Kousa, Florian Halbritter, Jason T Weiss, Anastasia Felker, Karel Bezstarosti, Rebecca Favaro, Jeroen Demmers, Silvia K Nicolis, Simon R Tomlinson, Raymond A Poot, Ian Chambers

EMBO J. 2013 Aug 14; 32(16): 2231–2247. Published online 2013 Jul 26. doi: 10.1038/emboj.2013.161

PMCID:: PMC3746198

Abstract Article PDF–2.9M

Select item 363035610.

The histone chaperone Spt6 coordinates histone H3K27 demethylation and myogenesis

A Hongjun Wang, Hossein Zare, Kambiz Mousavi, Chaochen Wang, Cara E Moravec, Howard I Sirotkin, Kai Ge, Gustavo Gutierrez-Cruz, Vittorio Sartorelli

EMBO J. 2013 Apr 17; 32(8): 1075–1086. Published online 2013 Mar 15. doi: 10.1038/emboj.2013.54

PMCID:: PMC3630356

Abstract Article PDF–2.1M

Select item 357241011.

A conditional knockout resource for the genome–wide study of mouse gene function

William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley

Nature. Author manuscript; available in PMC 2013 Feb 14.

Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163

PMCID:: PMC3572410

Abstract Article PDF–1.1M

Select item 346336012.

The Histone Chaperone Spt6 Is Required for Activation-induced Cytidine Deaminase Target Determination through H3K4me3 Regulation

Nasim A. Begum, Andre Stanlie, Mikiyo Nakata, Hideo Akiyama, Tasuku Honjo

J Biol Chem. 2012 Sep 21; 287(39): 32415–32429. Published online 2012 Jul 26. doi: 10.1074/jbc.M112.351569

PMCID:: PMC3463360

Abstract Article PDF–3.3M

Select item 317805913.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 309348714.

Histone chaperone Spt6 is required for class switch recombination but not somatic hypermutation

Il-mi Okazaki, Katsuya Okawa, Maki Kobayashi, Kiyotsugu Yoshikawa, Shimpei Kawamoto, Hitoshi Nagaoka, Reiko Shinkura, Yoko Kitawaki, Hisaaki Taniguchi, Tohru Natsume, Shun-Ichiro Iemura, Tasuku Honjo

Proc Natl Acad Sci U S A. 2011 May 10; 108(19): 7920–7925. Published online 2011 Apr 25. doi: 10.1073/pnas.1104423108

PMCID:: PMC3093487

Abstract Article PDF–667K

Select item 302253415.

A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo

Graciana Diez-Roux, Sandro Banfi, Marc Sultan, Lars Geffers, Santosh Anand, David Rozado, Alon Magen, Elena Canidio, Massimiliano Pagani, Ivana Peluso, Nathalie Lin-Marq, Muriel Koch, Marchesa Bilio, Immacolata Cantiello, Roberta Verde, Cristian De Masi, Salvatore A. Bianchi, Juliette Cicchini, Elodie Perroud, Shprese Mehmeti, Emilie Dagand, Sabine Schrinner, Asja Nürnberger, Katja Schmidt, Katja Metz, Christina Zwingmann, Norbert Brieske, Cindy Springer, Ana Martinez Hernandez, Sarah Herzog, Frauke Grabbe, Cornelia Sieverding, Barbara Fischer, Kathrin Schrader, Maren Brockmeyer, Sarah Dettmer, Christin Helbig, Violaine Alunni, Marie-Annick Battaini, Carole Mura, Charlotte N. Henrichsen, Raquel Garcia-Lopez, Diego Echevarria, Eduardo Puelles, Elena Garcia-Calero, Stefan Kruse, Markus Uhr, Christine Kauck, Guangjie Feng, Nestor Milyaev, Chuang Kee Ong, Lalit Kumar, MeiSze Lam, Colin A. Semple, Attila Gyenesei, Stefan Mundlos, Uwe Radelof, Hans Lehrach, Paolo Sarmientos, Alexandre Reymond, Duncan R. Davidson, Pascal Dollé, Stylianos E. Antonarakis, Marie-Laure Yaspo, Salvador Martinez, Richard A. Baldock, Gregor Eichele, Andrea Ballabio

PLoS Biol. 2011 Jan; 9(1): e1000582. Published online 2011 Jan 18. doi: 10.1371/journal.pbio.1000582

PMCID:: PMC3022534

Abstract Article PDF–3.8M

Select item 260707516.

The Iws1:Spt6:CTD complex controls cotranscriptional mRNA biosynthesis and HYPB/Setd2-mediated histone H3K36 methylation

Sunnie M. Yoh, Joseph S. Lucas, Katherine A. Jones

Genes Dev. 2008 Dec 15; 22(24): 3422–3434. doi: 10.1101/gad.1720008

PMCID:: PMC2607075

Abstract Article PDF–677K

Select item 255627017.

Large-scale gene trapping in C57BL/6N mouse embryonic stem cells

Gwenn M. Hansen, Diane C. Markesich, Michael B. Burnett, Qichao Zhu, Karen M. Dionne, Lizabeth J. Richter, Richard H. Finnell, Arthur T. Sands, Brian P. Zambrowicz, Alejandro Abuin

Genome Res. 2008 Oct; 18(10): 1670–1679. doi: 10.1101/gr.078352.108