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Items: 1 to 20 of 22

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Deficiency of PSRC1 accelerates atherosclerosis by increasing TMAO production via manipulating gut microbiota and flavin monooxygenase 3
Tiantian Luo, Zhigang Guo, Dan Liu, Zhongzhou Guo, Qiao Wu, Qinxian Li, Rongzhan Lin, Peier Chen, Caiwen Ou, Minsheng Chen
Gut Microbes. 2022; 14(1): 2077602. Published online 2022 May 25. doi: 10.1080/19490976.2022.2077602
PMCID:
PMC9135421
AbstractArticlePDF–7.6M
3.
Distinct roles of androgen receptor, estrogen receptor alpha, and BCL6 in the establishment of sex-biased DNA methylation in mouse liver
Najla AlOgayil, Klara Bauermeister, Jose Hector Galvez, Varun S. Venkatesh, Qinwei Kim-wee Zhuang, Matthew L. Chang, Rachel A. Davey, Jeffrey D. Zajac, Kinuyo Ida, Akihide Kamiya, Teruko Taketo, Guillaume Bourque, Anna K. Naumova
Sci Rep. 2021; 11: 13766. Published online 2021 Jul 2. doi: 10.1038/s41598-021-93216-6
Correction in:
Sci Rep. 2021; 11: 22975.
PMCID:
PMC8253761
AbstractArticlePDF–7.9M
4.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
5.
Genetic deficiency of flavin containing monooxygenase 3 (Fmo3) protects against thrombosis but has only a minor effect on plasma lipid levels
Diana M. Shih, Weifei Zhu, Rebecca C. Schugar, Yonghong Meng, Xun Jia, Aika Miikeda, Zeneng Wang, Marina Zieger, Richard Lee, Mark Graham, Hooman Allayee, Rita M. Cantor, Christian Mueller, J. Mark Brown, Stanley L. Hazen, Aldons J. Lusis
Arterioscler Thromb Vasc Biol. Author manuscript; available in PMC 2020 Jun 1.
Published in final edited form as: Arterioscler Thromb Vasc Biol. 2019 Jun; 39(6): 1045–1054. doi: 10.1161/ATVBAHA.119.312592
PMCID:
PMC6531332
AbstractArticlePDF–696K
6.
Flavin monooxygenase 3, the host hepatic enzyme in the metaorganismal trimethylamine N-oxide-generating pathway, modulates platelet responsiveness and thrombosis risk
W. Zhu, J. A. Buffa, Z. Wang, M. Warrier, R. Schugar, D. M. Shih, N. Gupta, J. C. Gregory, E. Org, X. Fu, L. Li, J. A. DiDonato, A. J. Lusis, J. M. Brown, S. L. Hazen
J Thromb Haemost. Author manuscript; available in PMC 2019 Sep 1.
Published in final edited form as: J Thromb Haemost. 2018 Sep; 16(9): 1857–1872. Published online 2018 Aug 9. doi: 10.1111/jth.14234
PMCID:
PMC6156942
AbstractArticlePDF–2.1M
7.
Lactobacillus plantarum reverse diabetes-induced Fmo3 and ICAM expression in mice through enteric dysbiosis-related c-Jun NH2-terminal kinase pathways
Wen-Chung Liu, Ming-Chieh Yang, Ying-Ying Wu, Pei-Hsuan Chen, Ching-Mei Hsu, Lee-Wei Chen
PLoS One. 2018; 13(5): e0196511. Published online 2018 May 31. doi: 10.1371/journal.pone.0196511
PMCID:
PMC5978885
AbstractArticlePDF–5.4M
8.
The TMAO-Producing Enzyme Flavin-Containing Monooxygenase 3 (FMO3) Regulates Obesity and the Beiging of White Adipose Tissue
Rebecca C. Schugar, Diana M. Shih, Manya Warrier, Robert N. Helsley, Amy Burrows, Daniel Ferguson, Amanda L. Brown, Anthony D. Gromovsky, Markus Heine, Arunachal Chatterjee, Lin Li, Xinmin S. Li, Zeneng Wang, Belinda Willard, YongHong Meng, Hanjun Kim, Nam Che, Calvin Pan, Richard G. Lee, Rosanne M. Crooke, Mark J. Graham, Richard E. Morton, Carl D. Langefeld, Swapan K. Das, Lawrence L. Rudel, Nizar Zein, Arthur J. McCullough, Srinivasan Dasarathy, W.H. Wilson Tang, Bernadette O. Erokwu, Chris A. Flask, Markku Laakso, Mete Civelek, Sathyamangla V. Naga Prasad, Joerg Heeren, Aldons J. Lusis, Stanley L. Hazen, J. Mark Brown
Cell Rep. Author manuscript; available in PMC 2017 Nov 6.
Published in final edited form as: Cell Rep. 2017 Jun 20; 19(12): 2451–2461. doi: 10.1016/j.celrep.2017.05.077
Correction in:
Cell Rep. 2017 Jul 5; 20(1): 279.
PMCID:
PMC5672822
AbstractArticlePDF–2.5M
9.
Flavin-Containing Monooxygenase 3 Reduces Endoplasmic Reticulum Stress in Lipid-Treated Hepatocytes
Bing M. Liao, Sophie A. McManus, William E. Hughes, Carsten Schmitz-Peiffer
Mol Endocrinol. 2016 Apr; 30(4): 417–428. Published online 2016 Feb 17. doi: 10.1210/me.2015-1217
PMCID:
PMC5414645
AbstractArticle
10.
Differential Fmo3 Gene Expression in Various Liver Injury Models Involving Hepatic Oxidative Stress in Mice
Swetha Rudraiah, Jamie E. Moscovitz, Ajay C. Donepudi, Sarah N. Campion, Angela L. Slitt, Lauren M. Aleksunes, José E. Manautou
Toxicology. Author manuscript; available in PMC 2015 Nov 5.
Published in final edited form as: Toxicology. 2014 Nov 5; 325: 85–95. Published online 2014 Sep 2. doi: 10.1016/j.tox.2014.08.013
PMCID:
PMC4428328
AbstractArticlePDF–3.9M
11.
Flavin-containing monooxygenase 3 as a potential player in diabetes-associated atherosclerosis
Ji Miao, Alisha V. Ling, Praveen V. Manthena, Mary E. Gearing, Mark J. Graham, Rosanne M. Crooke, Kevin J. Croce, Ryan M. Esquejo, Clary B. Clish, Morbid Obesity Study Group, David Vicent, Sudha B. Biddinger
Nat Commun. 2015 Apr 7; 6: 6498. Published online 2015 Apr 7. doi: 10.1038/ncomms7498
PMCID:
PMC4391288
AbstractArticlePDF–1.0M
12.
Flavin containing monooxygenase 3 exerts broad effects on glucose and lipid metabolism and atherosclerosis
Diana M. Shih, Zeneng Wang, Richard Lee, Yonghong Meng, Nam Che, Sarada Charugundla, Hannah Qi, Judy Wu, Calvin Pan, J. Mark Brown, Thomas Vallim, Brian J. Bennett, Mark Graham, Stanley L. Hazen, Aldons J. Lusis
J Lipid Res. 2015 Jan; 56(1): 22–37. doi: 10.1194/jlr.M051680
PMCID:
PMC4274068
AbstractArticlePDF–1.3M
13.
Tolerance to Acetaminophen Hepatotoxicity in the Mouse Model of Autoprotection Is Associated with Induction of Flavin-Containing Monooxygenase-3 (FMO3) in Hepatocytes
Swetha Rudraiah, Philip R. Rohrer, Igor Gurevich, Michael J. Goedken, Theodore Rasmussen, Ronald N. Hines, José E. Manautou
Toxicol Sci. 2014 Sep 1; 141(1): 263–277. Published online 2014 Sep 12. doi: 10.1093/toxsci/kfu124
PMCID:
PMC4271123
AbstractArticlePDF–4.7M
14.
Trimethylamine-N-Oxide, a Metabolite Associated with Atherosclerosis, Exhibits Complex Genetic and Dietary Regulation
Brian J. Bennett, Thomas Q. de Aguiar Vallim, Zeneng Wang, Diana M. Shih, Yonghong Meng, Jill Gregory, Hooman Allayee, Richard Lee, Mark Graham, Rosanne Crooke, Peter A. Edwards, Stanley L. Hazen, Aldons J. Lusis
Cell Metab. Author manuscript; available in PMC 2014 Jan 8.
Published in final edited form as: Cell Metab. 2013 Jan 8; 17(1): 49–60. doi: 10.1016/j.cmet.2012.12.011
PMCID:
PMC3771112
AbstractArticlePDF–3.1M
15.
Selective Modulation of Hepatic Cytochrome P450 and Flavin Monooxygenase 3 Expression during Citrobacter rodentium Infection in Severe Combined Immune-Deficient Mice
Beatrice A. Nyagode, William J. Watkins, Ryan D. Kinloch, Edward T. Morgan
Drug Metab Dispos. 2012 Oct; 40(10): 1894–1899. doi: 10.1124/dmd.112.046557
PMCID:
PMC3463824
AbstractArticlePDF–1.0M
16.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
17.
A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo
Graciana Diez-Roux, Sandro Banfi, Marc Sultan, Lars Geffers, Santosh Anand, David Rozado, Alon Magen, Elena Canidio, Massimiliano Pagani, Ivana Peluso, Nathalie Lin-Marq, Muriel Koch, Marchesa Bilio, Immacolata Cantiello, Roberta Verde, Cristian De Masi, Salvatore A. Bianchi, Juliette Cicchini, Elodie Perroud, Shprese Mehmeti, Emilie Dagand, Sabine Schrinner, Asja Nürnberger, Katja Schmidt, Katja Metz, Christina Zwingmann, Norbert Brieske, Cindy Springer, Ana Martinez Hernandez, Sarah Herzog, Frauke Grabbe, Cornelia Sieverding, Barbara Fischer, Kathrin Schrader, Maren Brockmeyer, Sarah Dettmer, Christin Helbig, Violaine Alunni, Marie-Annick Battaini, Carole Mura, Charlotte N. Henrichsen, Raquel Garcia-Lopez, Diego Echevarria, Eduardo Puelles, Elena Garcia-Calero, Stefan Kruse, Markus Uhr, Christine Kauck, Guangjie Feng, Nestor Milyaev, Chuang Kee Ong, Lalit Kumar, MeiSze Lam, Colin A. Semple, Attila Gyenesei, Stefan Mundlos, Uwe Radelof, Hans Lehrach, Paolo Sarmientos, Alexandre Reymond, Duncan R. Davidson, Pascal Dollé, Stylianos E. Antonarakis, Marie-Laure Yaspo, Salvador Martinez, Richard A. Baldock, Gregor Eichele, Andrea Ballabio
PLoS Biol. 2011 Jan; 9(1): e1000582. Published online 2011 Jan 18. doi: 10.1371/journal.pbio.1000582
PMCID:
PMC3022534
AbstractArticlePDF–3.8M
18.
BGEM: An In Situ Hybridization Database of Gene Expression in the Embryonic and Adult Mouse Nervous System
Susan Magdaleno, Patricia Jensen, Craig L Brumwell, Anna Seal, Karen Lehman, Andrew Asbury, Tony Cheung, Tommie Cornelius, Diana M Batten, Christopher Eden, Shannon M Norland, Dennis S Rice, Nilesh Dosooye, Sundeep Shakya, Perdeep Mehta, Tom Curran
PLoS Biol. 2006 Apr; 4(4): e86. Published online 2006 Mar 28. doi: 10.1371/journal.pbio.0040086
PMCID:
PMC1413568
ArticlePDF–99K
19.
Searching QTL by gene expression: analysis of diabesity
Aaron C Brown, William I Olver, Charles J Donnelly, Marjorie E May, Jürgen K Naggert, Daniel J Shaffer, Derry C Roopenian
BMC Genet. 2005; 6: 12. Published online 2005 Mar 10. doi: 10.1186/1471-2156-6-12
PMCID:
PMC555939
AbstractArticlePDF–414K
20.
RIKEN Integrated Sequence Analysis (RISA) System—384-Format Sequencing Pipeline with 384 Multicapillary Sequencer
Kazuhiro Shibata, Masayoshi Itoh, Katsunori Aizawa, Sumiharu Nagaoka, Nobuya Sasaki, Piero Carninci, Hideaki Konno, Junichi Akiyama, Katsuo Nishi, Tokuji Kitsunai, Hideo Tashiro, Mari Itoh, Noriko Sumi, Yoshiyuki Ishii, Shin Nakamura, Makoto Hazama, Tsutomu Nishine, Akira Harada, Rintaro Yamamoto, Hiroyuki Matsumoto, Sumito Sakaguchi, Takashi Ikegami, Katsuya Kashiwagi, Syuji Fujiwake, Kouji Inoue, Yoshiyuki Togawa, Masaki Izawa, Eiji Ohara, Masanori Watahiki, Yuko Yoneda, Tomokazu Ishikawa, Kaori Ozawa, Takumi Tanaka, Shuji Matsuura, Jun Kawai, Yasushi Okazaki, Masami Muramatsu, Yorinao Inoue, Akira Kira, Yoshihide Hayashizaki
Genome Res. 2000 Nov; 10(11): 1757–1771. doi: 10.1101/gr.152600
PMCID:
PMC310992
AbstractArticlePDF–3.4M

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