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Select item 103078521.

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility

Juan Gu, Pingyang Ke, Haokun Guo, Jing Liu, Yan Liu, Xin Tian, Zhuo Huang, Xin Xu, Demei Xu, Yuanlin Ma, Xuefeng Wang, Fei Xiao

Cell Death Differ. 2023 Jul; 30(7): 1726–1741. Published online 2023 May 4. doi: 10.1038/s41418-023-01174-5

PMCID:: PMC10307852

Abstract Article PDF–8.8M

Select item 102089582.

Impaired OTUD7A-dependent Ankyrin regulation mediates neuronal dysfunction in mouse and human models of the 15q13.3 microdeletion syndrome

Brianna K. Unda, Leon Chalil, Sehyoun Yoon, Savannah Kilpatrick, Courtney Irwin, Sansi Xing, Nadeem Murtaza, Anran Cheng, Chad Brown, Alexandria Afonso, Elizabeth McCready, Gabriel M. Ronen, Jennifer Howe, Aurélie Caye-Eude, Alain Verloes, Brad W. Doble, Laurence Faivre, Antonio Vitobello, Stephen W. Scherer, Yu Lu, Peter Penzes, Karun K. Singh

Mol Psychiatry. 2023; 28(4): 1747–1769. Published online 2023 Jan 6. doi: 10.1038/s41380-022-01937-5

PMCID:: PMC10208958

Abstract Article PDF–7.0M

Select item 95136043.

Distinct overlapping functions for Prickle1 and Prickle2 in the polarization of the airway epithelium

Koshi Kunimoto, Alexis T. Weiner, Jeffrey D. Axelrod, Eszter K. Vladar

Front Cell Dev Biol. 2022; 10: 976182. Published online 2022 Sep 13. doi: 10.3389/fcell.2022.976182

PMCID:: PMC9513604

Abstract Article PDF–3.4M

Select item 86434994.

Loss of Zic3 impairs planar cell polarity leading to abnormal left–right signaling, heart defects and neural tube defects

Helen M Bellchambers, Stephanie M Ware

Hum Mol Genet. 2021 Dec 15; 30(24): 2402–2415. Published online 2021 Jul 19. doi: 10.1093/hmg/ddab195

PMCID:: PMC8643499

Abstract Article PDF–1.3M

Select item 84944395.

Prickle promotes the formation and maintenance of glutamatergic synapses by stabilizing the intercellular planar cell polarity complex

Yue Ban, Ting Yu, Bo Feng, Charlotte Lorenz, Xiaojia Wang, Clayton Baker, Yimin Zou

Sci Adv. 2021 Oct; 7(41): eabh2974. Published online 2021 Oct 6. doi: 10.1126/sciadv.abh2974

PMCID:: PMC8494439

Abstract Article PDF–2.4M

Select item 83132396.

Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development

Francesco Bedogni, Robert F. Hevner

Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034

PMCID:: PMC8313239

Abstract Article PDF–1.6M

Select item 80941167.

Planar cell polarity induces local microtubule bundling for coordinated ciliary beating

Shogo Nakayama, Tomoki Yano, Toshinori Namba, Satoshi Konishi, Maki Takagishi, Elisa Herawati, Tomoki Nishida, Yasuo Imoto, Shuji Ishihara, Masahide Takahashi, Ken’ya Furuta, Kazuhiro Oiwa, Atsushi Tamura, Sachiko Tsukita

J Cell Biol. 2021 Jul 5; 220(7): e202010034. Published online 2021 Apr 30. doi: 10.1083/jcb.202010034

PMCID:: PMC8094116

Abstract Article PDF–9.9M

Select item 79743848.

A Wnt5 Activity Asymmetry and Intercellular Signaling via PCP Proteins Polarize Node Cells for Left-Right Symmetry Breaking

Katsura Minegishi, Masakazu Hashimoto, Rieko Ajima, Katsuyoshi Takaoka, Kyosuke Shinohara, Yayoi Ikawa, Hiromi Nishimura, Andrew P. McMahon, Karl Willert, Yasushi Okada, Hiroshi Sasaki, Dongbo Shi, Toshihiko Fujimori, Toshihisa Ohtsuka, Yasunobu Igarashi, Terry P. Yamaguchi, Akihiko Shimono, Hidetaka Shiratori, Hiroshi Hamada

Dev Cell. Author manuscript; available in PMC 2021 Mar 19.

Published in final edited form as: Dev Cell. 2017 Mar 13; 40(5): 439–452.e4. doi: 10.1016/j.devcel.2017.02.010

PMCID:: PMC7974384

Abstract Article PDF–3.5M

Select item 79387709.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 764521310.

Malformation of Tear Ducts Underlies the Epiphora and Precocious Eyelid Opening in Prickle 1 Mutant Mice: Genetic Implications for Tear Duct Genesis

Jiali Ru, Dianlei Guo, Jiaying Fan, Jiao Zhang, Rong Ju, Hong Ouyang, Lai Wei, Yizhi Liu, Chunqiao Liu

Invest Ophthalmol Vis Sci. 2020 Nov; 61(13): 6. Published online 2020 Nov 3. doi: 10.1167/iovs.61.13.6

PMCID:: PMC7645213

Abstract Article PDF–35M

Select item 750943111.

Upregulation of Prickle2 Ameliorates Alzheimer’s Disease-Like Pathology in a Transgenic Mouse Model of Alzheimer’s Disease

Fengxian Sun, Fang Jiang, Na Zhang, Hua Li, Weiping Tian, Weiying Liu

Front Cell Dev Biol. 2020; 8: 565020. Published online 2020 Sep 8. doi: 10.3389/fcell.2020.565020

PMCID:: PMC7509431

Abstract Article PDF–6.3M

Select item 729503312.

Ex vivo Quantitative Proteomic Analysis of Serotonin Transporter Interactome: Network Impact of the SERT Ala56 Coding Variant

Meagan A. Quinlan, Matthew J. Robson, Ran Ye, Kristie L. Rose, Kevin L. Schey, Randy D. Blakely

Front Mol Neurosci. 2020; 13: 89. Published online 2020 Jun 8. doi: 10.3389/fnmol.2020.00089

PMCID:: PMC7295033

Abstract Article PDF–2.7M

Select item 667248313.

Asymmetric Distribution of Prickle-Like 2 Reveals an Early Underlying Polarization of Vestibular Sensory Epithelia in the Inner Ear

Michael R. Deans, Dragana Antic, Kaye Suyama, Matthew P. Scott, Jeffrey D. Axelrod, Lisa V. Goodrich

J Neurosci. 2007 Mar 21; 27(12): 3139–3147. doi: 10.1523/JNEUROSCI.5151-06.2007

PMCID:: PMC6672483

Abstract Article PDF–464K

Select item 650659914.

VANGL2 regulates luminal epithelial organization and cell turnover in the mammary gland

Prestina Smith, Nathan Godde, Stefany Rubio, Melawit Tekeste, Eszter K. Vladar, Jeffrey D. Axelrod, Deborah J. Henderson, Michal Milgrom-Hoffman, Patrick O. Humbert, Lindsay Hinck

Sci Rep. 2019; 9: 7079. Published online 2019 May 8. doi: 10.1038/s41598-019-43444-8

PMCID:: PMC6506599

Abstract Article PDF–2.9M

Select item 639353615.

Vangl2 interaction plays a role in the proteasomal degradation of Prickle2

Tadahiro Nagaoka, Mikio Furuse, Toshihisa Ohtsuka, Kunihiro Tsuchida, Masashi Kishi

Sci Rep. 2019; 9: 2912. Published online 2019 Feb 27. doi: 10.1038/s41598-019-39642-z

PMCID:: PMC6393536

Abstract Article PDF–1.8M

Select item 589963616.

Domineering Non-Autonomy in Vangl1;Vangl2 Double Mutants Demonstrates Intercellular PCP Signaling in the Vertebrate Inner Ear

Michelle L. Stoller, Orvelin Roman, Jr., Michael R. Deans

Dev Biol. Author manuscript; available in PMC 2019 May 1.

Published in final edited form as: Dev Biol. 2018 May 1; 437(1): 17–26. Published online 2018 Mar 3. doi: 10.1016/j.ydbio.2018.02.021

PMCID:: PMC5899636

Abstract Article PDF–2.0M

Select item 570207417.

A tectorin-based matrix and planar cell polarity genes are required for normal collagen-fibril orientation in the developing tectorial membrane

Richard J. Goodyear, Xiaowei Lu, Michael R. Deans, Guy P. Richardson

Development. 2017 Nov 1; 144(21): 3978–3989. doi: 10.1242/dev.151696

PMCID:: PMC5702074

Abstract Article

Select item 538853818.

Transcription factor Emx2 controls stereociliary bundle orientation of sensory hair cells

Tao Jiang, Katie Kindt, Doris K Wu

eLife. 2017; 6: e23661. Published online 2017 Mar 7. doi: 10.7554/eLife.23661

PMCID:: PMC5388538

Abstract Article PDF–22M

Select item 489266319.

A mutation in the tuft mouse disrupts TET1 activity and alters the expression of genes that are crucial for neural tube closure

Keith S. K. Fong, Robert B. Hufnagel, Vedbar S. Khadka, Michael J. Corley, Alika K. Maunakea, Ben Fogelgren, Zubair M. Ahmed, Scott Lozanoff

Dis Model Mech. 2016 May 1; 9(5): 585–596. doi: 10.1242/dmm.024109

PMCID:: PMC4892663

Abstract Article

Select item 416374920.

Disruption of the non-canonical Wnt gene PRICKLE2 leads to autism-like behaviors with evidence for hippocampal synaptic dysfunction

L. P. Sowers, L. Loo, Y. Wu, E. Campbell, J. D. Ulrich, S. Wu, L. Paemka, T. Wassink, K. Meyer, X. Bing, H. El-Shanti, Y. M. Usachev, N. Ueno, R. J. Manak, A. J. Shepherd, P. J. Ferguson, B. W. Darbro, G. B. Richerson, D. P. Mohapatra, J. A. Wemmie, A. G. Bassuk

Mol Psychiatry. Author manuscript; available in PMC 2014 Oct 1.

Published in final edited form as: Mol Psychiatry. 2013 Oct; 18(10): 1077–1089. Published online 2013 May 28. doi: 10.1038/mp.2013.71

Correction in:: volume 19 on page 742

PMCID:: PMC4163749

Abstract Article PDF–2.3M

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