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Items: 1 to 20 of 62

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Blockade of Activin Receptor IIB Protects Arthritis Pathogenesis by Non‐Amplification of Activin A‐ACVR2B‐NOX4 Axis Pathway
Jimin Jeon, Hyemi Lee, Min‐Seung Jeon, Seok‐Jung Kim, Cham Choi, Ki Woo Kim, Dong Joo Yang, Sangho Lee, Yong‐Soo Bae, Won Il Choi, Juyeon Jung, Seong‐il Eyun, Siyoung Yang
Adv Sci (Weinh) 2023 May; 10(14): 2205161. Published online 2023 Mar 22. doi: 10.1002/advs.202205161
PMCID:
PMC10190289
AbstractArticlePDF–5.5M
3.
Functional interaction between Vangl2 and N-cadherin regulates planar cell polarization of the developing neural tube and cochlear sensory epithelium
Tadahiro Nagaoka, Tatsuya Katsuno, Kyoka Fujimura, Kunihiro Tsuchida, Masashi Kishi
Sci Rep. 2023; 13: 3905. Published online 2023 Mar 8. doi: 10.1038/s41598-023-30213-x
PMCID:
PMC9995352
AbstractArticlePDF–5.7M
4.
Local versus systemic control of bone and skeletal muscle mass by components of the transforming growth factor-β signaling pathway
Yewei Liu, Adam Lehar, Renata Rydzik, Harshpreet Chandok, Yun-Sil Lee, Daniel W. Youngstrom, Joshy George, Martin M. Matzuk, Emily L. Germain-Lee, Se-Jin Lee
Proc Natl Acad Sci U S A. 2021 Aug 17; 118(33): e2111401118. Published online 2021 Aug 12. doi: 10.1073/pnas.2111401118
PMCID:
PMC8379946
AbstractArticlePDF–1.8M
5.
Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development
Francesco Bedogni, Robert F. Hevner
Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034
PMCID:
PMC8313239
AbstractArticlePDF–1.6M
6.
Endometrial receptivity and implantation require uterine BMP signaling through an ACVR2A-SMAD1/SMAD5 axis
Diana Monsivais, Takashi Nagashima, Renata Prunskaite-Hyyryläinen, Kaori Nozawa, Keisuke Shimada, Suni Tang, Clark Hamor, Julio E. Agno, Fengju Chen, Ramya P. Masand, Steven L. Young, Chad J. Creighton, Francesco J. DeMayo, Masahito Ikawa, Se-Jin Lee, Martin M. Matzuk
Nat Commun. 2021; 12: 3386. Published online 2021 Jun 7. doi: 10.1038/s41467-021-23571-5
PMCID:
PMC8184938
AbstractArticlePDF–18M
7.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
8.
Development of a Highly Sensitive ELISA for Measurement of FSH in Serum, Plasma, and Whole Blood in Mice
Luisina Ongaro, Carlos Agustin Isidro Alonso, Xiang Zhou, Emilie Brûlé, Yining Li, Gauthier Schang, Albert F Parlow, Frederik Steyn, Daniel J Bernard
Endocrinology. 2021 Apr; 162(4): bqab014. Published online 2021 Jan 21. doi: 10.1210/endocr/bqab014
PMCID:
PMC7894055
AbstractArticle
9.
Targeting myostatin/activin A protects against skeletal muscle and bone loss during spaceflight
Se-Jin Lee, Adam Lehar, Jessica U. Meir, Christina Koch, Andrew Morgan, Lara E. Warren, Renata Rydzik, Daniel W. Youngstrom, Harshpreet Chandok, Joshy George, Joseph Gogain, Michael Michaud, Thomas A. Stoklasek, Yewei Liu, Emily L. Germain-Lee
Proc Natl Acad Sci U S A. 2020 Sep 22; 117(38): 23942–23951. Published online 2020 Sep 8. doi: 10.1073/pnas.2014716117
PMCID:
PMC7519220
AbstractArticlePDF–1.2M
10.
Murine FSH Production Depends on the Activin Type II Receptors ACVR2A and ACVR2B
Gauthier Schang, Luisina Ongaro, Hailey Schultz, Ying Wang, Xiang Zhou, Emilie Brûlé, Ulrich Boehm, Se-Jin Lee, Daniel J Bernard
Endocrinology. 2020 Jul; 161(7): bqaa056. Published online 2020 Apr 9. doi: 10.1210/endocr/bqaa056
PMCID:
PMC7286621
AbstractArticle
11.
An enhancer cluster controls gene activity and topology of the SCN5A-SCN10A locus in vivo
Joyce C. K. Man, Rajiv A. Mohan, Malou van den Boogaard, Catharina R. E. Hilvering, Catherine Jenkins, Vincent Wakker, Valerio Bianchi, Wouter de Laat, Phil Barnett, Bastiaan J. Boukens, Vincent M. Christoffels
Nat Commun. 2019; 10: 4943. Published online 2019 Oct 30. doi: 10.1038/s41467-019-12856-5
PMCID:
PMC6821807
AbstractArticlePDF–2.9M
12.
The TGFβ type I receptor TGFβRI functions as an inhibitor of BMP signaling in cartilage
Weiguang Wang, Hyelim Chun, Jongseung Baek, Joshua Elyahu Sadik, Anna Shirazyan, Peyman Razavi, Noah Lopez, Karen M. Lyons
Proc Natl Acad Sci U S A. 2019 Jul 30; 116(31): 15570–15579. Published online 2019 Jul 16. doi: 10.1073/pnas.1902927116
PMCID:
PMC6681752
AbstractArticlePDF–2.4M
13.
CITGeneDB: a comprehensive database of human and mouse genes enhancing or suppressing cold-induced thermogenesis validated by perturbation experiments in mice
Jin Li, Su-Ping Deng, Gang Wei, Peng Yu
Database (Oxford) 2018; 2018: bay012. Published online 2018 Mar 23. doi: 10.1093/database/bay012
PMCID:
PMC5868181
AbstractArticlePDF–653K
14.
Cerebral vein malformations result from loss of Twist1 expression and BMP signaling from skull progenitor cells and dura
Max A. Tischfield, Caroline D. Robson, Nicole M. Gilette, Shek Man Chim, Folasade A. Sofela, Michelle M. DeLisle, Alon Gelber, Brenda J. Barry, Sarah MacKinnon, Linda R. Dagi, Jeremy Nathans, Elizabeth C. Engle
Dev Cell. Author manuscript; available in PMC 2018 Sep 11.
Published in final edited form as: Dev Cell. 2017 Sep 11; 42(5): 445–461.e5. Published online 2017 Aug 30. doi: 10.1016/j.devcel.2017.07.027
PMCID:
PMC5595652
AbstractArticlePDF–2.0M
15.
Activin receptor type 2A (ACVR2A) functions directly in osteoblasts as a negative regulator of bone mass
Brian C. Goh, Vandana Singhal, Angelica J. Herrera, Ryan E. Tomlinson, Soohyun Kim, Marie-Claude Faugere, Emily L. Germain-Lee, Thomas L. Clemens, Se-Jin Lee, Douglas J. DiGirolamo
J Biol Chem. 2017 Aug 18; 292(33): 13809–13822. Published online 2017 Jun 28. doi: 10.1074/jbc.M117.782128
PMCID:
PMC5566533
AbstractArticlePDF–3.1M
16.
Follistatin Targets Distinct Pathways To Promote Brown Adipocyte Characteristics in Brown and White Adipose Tissues
Rajan Singh, Melissa Braga, Srinivasa T. Reddy, Se-Jin Lee, Meher Parveen, Victor Grijalva, Laurent Vergnes, Shehla Pervin
Endocrinology. 2017 May 1; 158(5): 1217–1230. Published online 2017 Jan 16. doi: 10.1210/en.2016-1607
PMCID:
PMC5460830
AbstractArticle
17.
Activin A induces skeletal muscle catabolism via p38β mitogen‐activated protein kinase
Hui Ding, Guohua Zhang, Ka Wai Thomas Sin, Zhelong Liu, Ren‐Kuo Lin, Min Li, Yi‐Ping Li
J Cachexia Sarcopenia Muscle. 2017 Apr; 8(2): 202–212. Published online 2016 Sep 16. doi: 10.1002/jcsm.12145
PMCID:
PMC5377410
AbstractArticlePDF–828K
18.
High-throughput discovery of novel developmental phenotypes
Mary E. Dickinson, Ann M. Flenniken, Xiao Ji, Lydia Teboul, Michael D. Wong, Jacqueline K. White, Terrence F. Meehan, Wolfgang J. Weninger, Henrik Westerberg, Hibret Adissu, Candice N. Baker, Lynette Bower, James M. Brown, L. Brianna Caddle, Francesco Chiani, Dave Clary, James Cleak, Mark J. Daly, James M. Denegre, Brendan Doe, Mary E. Dolan, Sarah M. Edie, Helmut Fuchs, Valerie Gailus-Durner, Antonella Galli, Alessia Gambadoro, Juan Gallegos, Shiying Guo, Neil R. Horner, Chih-wei Hsu, Sara J. Johnson, Sowmya Kalaga, Lance C. Keith, Louise Lanoue, Thomas N. Lawson, Monkol Lek, Manuel Mark, Susan Marschall, Jeremy Mason, Melissa L. McElwee, Susan Newbigging, Lauryl M.J. Nutter, Kevin A. Peterson, Ramiro Ramirez-Solis, Douglas J. Rowland, Edward Ryder, Kaitlin E. Samocha, John R. Seavitt, Mohammed Selloum, Zsombor Szoke-Kovacs, Masaru Tamura, Amanda G Trainor, Ilinca Tudose, Shigeharu Wakana, Jonathan Warren, Olivia Wendling, David B. West, Leeyean Wong, Atsushi Yoshiki, The International Mouse Phenotyping Consortium, Daniel G. MacArthur, Glauco P. Tocchini-Valentini, Xiang Gao, Paul Flicek, Allan Bradley, William C. Skarnes, Monica J. Justice, Helen E. Parkinson, Mark Moore, Sara Wells, Robert E. Braun, Karen L. Svenson, Martin Hrabe de Angelis, Yann Herault, Tim Mohun, Ann-Marie Mallon, R. Mark Henkelman, Steve D.M. Brown, David J. Adams, K.C. Kent Lloyd, Colin McKerlie, Arthur L. Beaudet, Maja Bucan, Stephen A. Murray
Nature. Author manuscript; available in PMC 2017 Mar 14.
Published in final edited form as: Nature. 2016 Sep 22; 537(7621): 508–514. Published online 2016 Sep 14. doi: 10.1038/nature19356
Correction in:
Nature. 2017 Nov 16; 551(7680): 398.
PMCID:
PMC5295821
AbstractArticlePDF–3.0M
19.
The ability of inner cell mass cells to self-renew as embryonic stem cells is acquired upon epiblast specification
Thorsten Boroviak, Remco Loos, Paul Bertone, Austin Smith, Jennifer Nichols
Nat Cell Biol. Author manuscript; available in PMC 2016 May 24.
Published in final edited form as: Nat Cell Biol. 2014 Jun; 16(6): 516–528. Published online 2014 May 25. doi: 10.1038/ncb2965
PMCID:
PMC4878656
AbstractArticlePDF–7.9M
20.
Mutant GDF5 enhances ameloblast differentiation via accelerated BMP2-induced Smad1/5/8 phosphorylation
Jia Liu, Kan Saito, Yuriko Maruya, Takashi Nakamura, Aya Yamada, Emiko Fukumoto, Momoko Ishikawa, Tsutomu Iwamoto, Kanako Miyazaki, Keigo Yoshizaki, Lihong Ge, Satoshi Fukumoto
Sci Rep. 2016; 6: 23670. Published online 2016 Mar 31. doi: 10.1038/srep23670
PMCID:
PMC4814822
AbstractArticlePDF–1.8M

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