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Select item 107693501.

Identification of new ciliary signaling pathways in the brain and insights into neurological disorders

Abdelhalim Loukil, Emma Ebright, Akiyoshi Uezu, Yudong Gao, Scott H Soderling, Sarah C. Goetz

Version 1. bioRxiv. Preprint. 2023 Dec 21. doi: 10.1101/2023.12.20.572700

PMCID:: PMC10769350

Abstract Article PDF–11M

Select item 96316342.

Impaired microtubule dynamics contribute to microthrombocytopenia in RhoB-deficient mice

Maximilian Englert, Katja Aurbach, Isabelle C. Becker, Annika Gerber, Tobias Heib, Lou M. Wackerbarth, Charly Kusch, Kristina Mott, Gabriel H. M. Araujo, Ayesha A. Baig, Sebastian Dütting, Ulla G. Knaus, Christian Stigloher, Harald Schulze, Bernhard Nieswandt, Irina Pleines, Zoltan Nagy

Blood Adv. 2022 Sep 13; 6(17): 5184–5197. Published online 2022 Sep 6. doi: 10.1182/bloodadvances.2021006545

PMCID:: PMC9631634

Abstract Article PDF–2.9M

Select item 84529953.

Integrated Analysis of Prognostic Genes Associated With Ischemia–Reperfusion Injury in Renal Transplantation

Di Zhang, Yicun Wang, Song Zeng, Min Zhang, Xin Zhang, Yuxuan Wang, Zijian Zhang, Xi Wang, Xiaopeng Hu

Front Immunol. 2021; 12: 747020. Published online 2021 Sep 7. doi: 10.3389/fimmu.2021.747020

PMCID:: PMC8452995

Abstract Article PDF–3.7M

Select item 83132394.

Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development

Francesco Bedogni, Robert F. Hevner

Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034

PMCID:: PMC8313239

Abstract Article PDF–1.6M

Select item 81109565.

An infection-induced RhoB-Beclin 1-Hsp90 complex enhances clearance of uropathogenic Escherichia coli

Chunhui Miao, Mingyu Yu, Geng Pei, Zhenyi Ma, Lisong Zhang, Jianming Yang, Junqiang Lv, Zhi-Song Zhang, Evan T. Keller, Zhi Yao, Quan Wang

Nat Commun. 2021; 12: 2587. Published online 2021 May 10. doi: 10.1038/s41467-021-22726-8

PMCID:: PMC8110956

Abstract Article PDF–4.7M

Select item 79387706.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 66340837.

A Role for RhoB in Synaptic Plasticity and the Regulation of Neuronal Morphology

Kara McNair, Rosemary Spike, Clare Guilding, George C. Prendergast, Trevor W. Stone, Stuart R. Cobb, Brian J. Morris

J Neurosci. 2010 Mar 3; 30(9): 3508–3517. doi: 10.1523/JNEUROSCI.5386-09.2010

Correction in:: J Neurosci. 2017 Sep 20; 37(38): 9346.

PMCID:: PMC6634083

Abstract Article PDF–1.4M

Select item 64947908.

The TFAP2A–IRF6–GRHL3 genetic pathway is conserved in neurulation

Youssef A Kousa, Huiping Zhu, Walid D Fakhouri, Yunping Lei, Akira Kinoshita, Raeuf R Roushangar, Nicole K Patel, A J Agopian, Wei Yang, Elizabeth J Leslie, Tamara D Busch, Tamer A Mansour, Xiao Li, Arianna L Smith, Edward B Li, Dhruv B Sharma, Trevor J Williams, Yang Chai, Brad A Amendt, Eric C Liao, Laura E Mitchell, Alexander G Bassuk, Simon Gregory, Allison Ashley-Koch, Gary M Shaw, Richard H Finnell, Brian C Schutte

Hum Mol Genet. 2019 May 15; 28(10): 1726–1737. Published online 2019 Jan 25. doi: 10.1093/hmg/ddz010

PMCID:: PMC6494790

Abstract Article PDF–62M

Select item 63650859.

MicroRNA-223 attenuates LPS-induced inflammation in an acute lung injury model via the NLRP3 inflammasome and TLR4/NF-κB signaling pathway via RHOB

Yurong Yan, Kexin Lu, Ting Ye, Zongwang Zhang

Int J Mol Med. 2019 Mar; 43(3): 1467–1477. Published online 2019 Jan 23. doi: 10.3892/ijmm.2019.4075

PMCID:: PMC6365085

Abstract Article PDF–1.6M

Select item 578703310.

Kctd13 deletion reduces synaptic transmission via increased RhoA

Christine Ochoa Escamilla, Irina Filonova, Angela K. Walker, Zhong X. Xuan, Roopashri Holehonnur, Felipe Espinosa, Shunan Liu, Summer B. Thyme, Isabel A. López-García, Dorian B. Mendoza, Noriyoshi Usui, Jacob Ellegood, Amelia J. Eisch, Genevieve Konopka, Jason P. Lerch, Alexander F. Schier, Haley E. Speed, Craig M. Powell

Nature. Author manuscript; available in PMC 2018 Nov 9.

Published in final edited form as: Nature. 2017 Nov 9; 551(7679): 227–231. Published online 2017 Nov 1. doi: 10.1038/nature24470

PMCID:: PMC5787033

Abstract Article PDF–1.9M

Select item 571925111.

RhoB blockade selectively inhibits autoantibody production in autoimmune models of rheumatoid arthritis and lupus

Laura Mandik-Nayak, James B. DuHadaway, Jennifer Mulgrew, Elizabeth Pigott, Kaylend Manley, Summer Sedano, George C. Prendergast, Lisa D. Laury-Kleintop

Dis Model Mech. 2017 Nov 1; 10(11): 1313–1322. doi: 10.1242/dmm.029835

PMCID:: PMC5719251

Abstract Article

Select item 536087812.

RhoB regulates the function of macrophages in the hypoxia-induced inflammatory response

Gaoxiang Huang, Jie Su, Mingzhuo Zhang, Yiduo Jin, Yan Wang, Peng Zhou, Jian Lu

Cell Mol Immunol. 2017 Mar; 14(3): 265–275. Published online 2015 Sep 21. doi: 10.1038/cmi.2015.78

PMCID:: PMC5360878

Abstract Article PDF–1.1M

Select item 487245513.

Deletion of JMJD2B in neurons leads to defective spine maturation, hyperactive behavior and memory deficits in mouse

K Fujiwara, Y Fujita, A Kasai, Y Onaka, H Hashimoto, H Okada, T Yamashita

Transl Psychiatry. 2016 Mar; 6(3): e766. Published online 2016 Mar 29. doi: 10.1038/tp.2016.31

PMCID:: PMC4872455

Abstract Article PDF–1.1M

Select item 441793514.

Constraint and divergence of global gene expression in the mammalian embryo

Noah Spies, Cheryl L Smith, Jesse M Rodriguez, Julie C Baker, Serafim Batzoglou, Arend Sidow

eLife. 2015; 4: e05538. Published online 2015 Apr 14. doi: 10.7554/eLife.05538

PMCID:: PMC4417935

Abstract Article PDF–2.0M

Select item 438470415.

Altered apoptotic responses in neurons lacking RhoB GTPase

Sara Barberan, Kara McNair, Khalil Iqbal, Nicola C. Smith, George C. Prendergast, Trevor W. Stone, Stuart R. Cobb, Brian J. Morris

Eur J Neurosci. Author manuscript; available in PMC 2015 Apr 3.

Published in final edited form as: Eur J Neurosci. 2011 Dec; 34(11): 1737–1746. Published online 2011 Nov 18. doi: 10.1111/j.1460-9568.2011.07891.x

PMCID:: PMC4384704

Abstract Article PDF–2.1M

Select item 438469816.

RhoB Regulates PDGFR-β Trafficking and Signaling in Vascular Smooth Muscle Cells

Minzhou Huang, James B. DuHadaway, George C. Prendergast, Lisa D. Laury-Kleintop

Arterioscler Thromb Vasc Biol. Author manuscript; available in PMC 2015 Apr 3.

Published in final edited form as: Arterioscler Thromb Vasc Biol. 2007 Dec; 27(12): 2597–2605. Published online 2007 Oct 19. doi: 10.1161/ATVBAHA.107.154211

PMCID:: PMC4384698

Abstract Article PDF–2.3M

Select item 438469717.

Role of RhoB in the Regulation of Pulmonary Endothelial and Smooth Muscle Cell Responses to Hypoxia

Beata Wojciak-Stothard, Lan Zhao, Eduardo Oliver, Olivier Dubois, Yixing Wu, Dimitris Kardassis, Eleftheria Vasilaki, Minzhou Huang, Jane A. Mitchell, Louise S. Harrington, George C. Prendergast, Martin R. Wilkins

Circ Res. Author manuscript; available in PMC 2015 Apr 3.

Published in final edited form as: Circ Res. 2012 May 25; 110(11): 1423–1434. Published online 2012 Apr 26. doi: 10.1161/CIRCRESAHA.112.264473

Correction in:: volume 111 on page e163

PMCID:: PMC4384697

Abstract Article PDF–893K

Select item 421525418.

Mouse Macrophages Completely Lacking Rho Subfamily GTPases (RhoA, RhoB, and RhoC) Have Severe Lamellipodial Retraction Defects, but Robust Chemotactic Navigation and Altered Motility

Volker Königs, Richard Jennings, Thomas Vogl, Markus Horsthemke, Anne C. Bachg, Yan Xu, Kay Grobe, Cord Brakebusch, Albrecht Schwab, Martin Bähler, Ulla G. Knaus, Peter J. Hanley

J Biol Chem. 2014 Oct 31; 289(44): 30772–30784. Published online 2014 Sep 11. doi: 10.1074/jbc.M114.563270

PMCID:: PMC4215254

Abstract Article PDF–3.4M

Select item 420149819.

RhoB Differentially Controls Akt Function in Tumor Cells and Stromal Endothelial Cells during Breast Tumorigenesis

Shiva Kazerounian, Damien Gerald, Minzhou Huang, Y. Rebecca Chin, Durga Udayakumar, Ningning Zheng, Rebekah K. O'Donnell, Carole Perruzzi, Lee Mangiante, Jacob Pourat, Thuy L. Phung, Arturo Bravo-Nuevo, Sharon Shechter, Stephanie McNamara, James B. DuHadaway, Olivier N. Kocher, Lawrence F. Brown, Alex Toker, George C. Prendergast, Laura E. Benjamin

Cancer Res. Author manuscript; available in PMC 2014 Oct 17.

Published in final edited form as: Cancer Res. 2013 Jan 1; 73(1): 50–61. Published online 2012 Nov 7. doi: 10.1158/0008-5472.CAN-11-3055

PMCID:: PMC4201498

Abstract Article PDF–576K

Select item 413559920.

RhoB Promotes γH2AX Dephosphorylation and DNA Double-Strand Break Repair

Kenza Mamouni, Agnese Cristini, Josée Guirouilh-Barbat, Sylvie Monferran, Anthony Lemarié, Jean-Charles Faye, Bernard S. Lopez, Gilles Favre, Olivier Sordet

Mol Cell Biol. 2014 Aug; 34(16): 3144–3155. doi: 10.1128/MCB.01525-13

PMCID:: PMC4135599

Abstract Article PDF–2.0M

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