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Items: 1 to 20 of 57

1.
The Intellectual Disability Risk Gene Kdm5b Regulates Long-Term Memory Consolidation in the Hippocampus
Leticia Pérez-Sisqués, Shail U. Bhatt, Rugile Matuleviciute, Talia E. Gileadi, Eniko Kramar, Andrew Graham, Franklin G. Garcia, Ashley Keiser, Dina P. Matheos, James A. Cain, Alan M. Pittman, Laura C. Andreae, Cathy Fernandes, Marcelo A. Wood, K. Peter Giese, M. Albert Basson
J Neurosci. 2024 May 8; 44(19): e1544232024. Prepublished online 2024 Apr 4. doi: 10.1523/JNEUROSCI.1544-23.2024
PMCID:
PMC11079963
AbstractArticlePDF–3.4M
2.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
3.
The impact of rare protein coding genetic variation on adult cognitive function
Chia-Yen Chen, Ruoyu Tian, Tian Ge, Max Lam, Gabriela Sanchez-Andrade, Tarjinder Singh, Lea Urpa, Jimmy Z. Liu, Mark Sanderson, Christine Rowley, Holly Ironfield, Terry Fang, Biogen Biobank Team, The SUPER-Finland study, The Northern Finland Intellectual Disability study, Mark Daly, Aarno Palotie, Ellen A. Tsai, Hailiang Huang, Matthew E. Hurles, Sebastian S. Gerety, Todd Lencz, Heiko Runz
Nat Genet. 2023; 55(6): 927–938. Published online 2023 May 25. doi: 10.1038/s41588-023-01398-8
PMCID:
PMC10260403
AbstractArticlePDF–12M
4.
Histone demethylase KDM5B licenses macrophage-mediated inflammatory responses by repressing Nfkbia transcription
Yunkai Zhang, Ying Gao, Yuyu Jiang, Yingying Ding, Huiying Chen, Yan Xiang, Zhenzhen Zhan, Xingguang Liu
Cell Death Differ. 2023 May; 30(5): 1279–1292. Published online 2023 Mar 13. doi: 10.1038/s41418-023-01136-x
PMCID:
PMC10154333
AbstractArticlePDF–4.9M
5.
Loss of KDM5B ameliorates pathological cardiac fibrosis and dysfunction by epigenetically enhancing ATF3 expression
Bo Wang, Yong Tan, Yunkai Zhang, Sheng Zhang, Xuewen Duan, Yuyu Jiang, Tong Li, Qingqing Zhou, Xingguang Liu, Zhenzhen Zhan
Exp Mol Med. 2022 Dec; 54(12): 2175–2187. Published online 2022 Dec 8. doi: 10.1038/s12276-022-00904-y
PMCID:
PMC9794816
AbstractArticlePDF–6.4M
6.
Alcohol‐associated fibrosis in females is mediated by female‐specific activation of lysine demethylases KDM5B and KDM5C
Michael Schonfeld, Janice Averilla, Sumedha Gunewardena, Steven A. Weinman, Irina Tikhanovich
Hepatol Commun. 2022 Aug; 6(8): 2042–2057. Published online 2022 Apr 25. doi: 10.1002/hep4.1967
PMCID:
PMC9315128
AbstractArticlePDF–6.5M
7.
Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1–CoREST interactome during embryonic stem cell differentiation
Claire E. Barnes, David M. English, Megan Broderick, Mark O. Collins, Shaun M. Cowley
Mol Omics. 2022 Jan 17; 18(1): 31–44. Published online 2021 Oct 14. doi: 10.1039/d1mo00236h
PMCID:
PMC8763317
AbstractArticle
8.
KDM5B protein expressed in viable and fertile ΔARID mice exhibit no demethylase activity
Shirin Jamshidi, Steven Catchpole, Jie Chen, Chi Wai Eric So, Joy Burchell, Khondaker Miraz Rahman, Joyce Taylor-Papadimitriou
Int J Oncol. 2021 Nov; 59(5): 96. Published online 2021 Oct 27. doi: 10.3892/ijo.2021.5276
PMCID:
PMC8562390
AbstractArticlePDF–1.8M
9.
KDM5B Promotes Immune Evasion by Recruiting SETDB1 to Silence Retroelements
Shang-Min Zhang, Wesley L. Cai, Xiaoni Liu, Durga Thakral, Jiesi Luo, Lok Hei Chan, Meaghan K. McGeary, Eric Song, Kim RM Blenman, Goran Micevic, Shlomit Jessel, Yangyi Zhang, Mingzhu Yin, Carmen J. Booth, Lucia B. Jilaveanu, William Damsky, Mario Sznol, Harriet M. Kluger, Akiko Iwasaki, Marcus W. Bosenberg, Qin Yan
Nature. Author manuscript; available in PMC 2022 Apr 20.
Published in final edited form as: Nature. 2021 Oct; 598(7882): 682–687. Published online 2021 Oct 20. doi: 10.1038/s41586-021-03994-2
PMCID:
PMC8555464
AbstractArticlePDF–5.8M
10.
Identification of Jmjd3 as an Essential Epigenetic Regulator of Hox Gene Temporal Collinear Activation for Body Axial Patterning in Mice
Feng Zhang, Xiong Zhao, Runmin Jiang, Yuying Wang, Xinli Wang, Yu Gu, Longyong Xu, Jing Ye, Charlie Degui Chen, Shuangping Guo, Dawei Zhang, Daqing Zhao
Front Cell Dev Biol. 2021; 9: 642931. Published online 2021 Jul 21. doi: 10.3389/fcell.2021.642931
PMCID:
PMC8333871
AbstractArticlePDF–1.4M
11.
Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development
Francesco Bedogni, Robert F. Hevner
Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034
PMCID:
PMC8313239
AbstractArticlePDF–1.6M
12.
KDM5B is essential for the hyper-activation of PI3K/AKT signaling in prostate tumorigenesis
Guoliang Li, Thanigaivelan Kanagasabai, Wenfu Lu, Mike R. Zou, Shang-Min Zhang, Sherly I. Celada, Michael G. Izban, Qi Liu, Tao Lu, Billy R. Ballard, Xinchun Zhou, Samuel E. Adunyah, Robert J. Matusik, Qin Yan, Zhenbang Chen
Cancer Res. Author manuscript; available in PMC 2021 May 1.
Published in final edited form as: Cancer Res. 2020 Nov 1; 80(21): 4633–4643. Published online 2020 Aug 31. doi: 10.1158/0008-5472.CAN-20-0505
PMCID:
PMC8034842
AbstractArticlePDF–1.4M
13.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
14.
Distinct, dosage-sensitive requirements for the autism-associated factor CHD8 during cortical development
Shaun Hurley, Conor Mohan, Philipp Suetterlin, Robert Ellingford, Kimberley L. H. Riegman, Jacob Ellegood, Angela Caruso, Caterina Michetti, Olivier Brock, Romy Evans, Fabrizio Rudari, Alessio Delogu, Maria Luisa Scattoni, Jason P. Lerch, Cathy Fernandes, M. Albert Basson
Mol Autism. 2021; 12: 16. Published online 2021 Feb 24. doi: 10.1186/s13229-020-00409-3
PMCID:
PMC7905672
AbstractArticlePDF–5.7M
15.
Evidence for context-dependent functions of KDM5B in prostate development and prostate cancer
Bigang Liu, Rahul Kumar, Hseuh-Ping Chao, Rashid Mehmood, Yibing Ji, Amanda Tracz, Dean G. Tang
Oncotarget. 2020 Nov 17; 11(46): 4243–4252. Published online 2020 Nov 17. doi: 10.18632/oncotarget.27818
PMCID:
PMC7679033
AbstractArticlePDF–4.4M
16.
Interaction of Sox2 with RNA binding proteins in mouse embryonic stem cells
Samudyata, Paulo P. Amaral, Pär G. Engström, Samuel C. Robson, Michael L. Nielsen, Tony Kouzarides, Gonçalo Castelo-Branco
Exp Cell Res. Author manuscript; available in PMC 2020 Aug 1.
Published in final edited form as: Exp Cell Res. 2019 Aug 1; 381(1): 129–138. Published online 2019 May 9. doi: 10.1016/j.yexcr.2019.05.006
PMCID:
PMC6994247
AbstractArticlePDF–1.6M
17.
Quantifying the contribution of recessive coding variation to developmental disorders
Hilary C. Martin, Wendy D. Jones, Rebecca McIntyre, Gabriela Sanchez-Andrade, Mark Sanderson, James D. Stephenson, Carla P. Jones, Juliet Handsaker, Giuseppe Gallone, Michaela Bruntraeger, Jeremy F. McRae, Elena Prigmore, Patrick Short, Mari Niemi, Joanna Kaplanis, Elizabeth J. Radford, Nadia Akawi, Meena Balasubramanian, John Dean, Rachel Horton, Alice Hulbert, Diana S. Johnson, Katie Johnson, Dhavendra Kumar, Sally Ann Lynch, Sarju G. Mehta, Jenny Morton, Michael J. Parker, Miranda Splitt, Peter D Turnpenny, Pradeep C. Vasudevan, Michael Wright, Andrew Bassett, Sebastian S. Gerety, Caroline F. Wright, David R. FitzPatrick, Helen V. Firth, Matthew E. Hurles, Jeffrey C. Barrett
Science. Author manuscript; available in PMC 2019 Sep 4.
Published in final edited form as: Science. 2018 Dec 7; 362(6419): 1161–1164. Published online 2018 Nov 8. doi: 10.1126/science.aar6731
PMCID:
PMC6726470
AbstractArticlePDF–1.3M
18.
The Lysine Demethylase KDM5B Regulates Islet Function and Glucose Homeostasis
Marie Balslev Backe, Chunyu Jin, Luz Andreone, Aditya Sankar, Karl Agger, Kristian Helin, Andreas Nygaard Madsen, Steen Seier Poulsen, Madhusudhan Bysani, Karl Bacos, Charlotte Ling, Marcelo Javier Perone, Birgitte Holst, Thomas Mandrup-Poulsen
J Diabetes Res. 2019; 2019: 5451038. Published online 2019 Jul 28. doi: 10.1155/2019/5451038
PMCID:
PMC6701283
AbstractArticlePDF–3.4M
19.
Contribution of H3K4 demethylase KDM5B to nucleosome organization in embryonic stem cells revealed by micrococcal nuclease sequencing
Jiji T. Kurup, Ion J. Campeanu, Benjamin L. Kidder
Epigenetics Chromatin. 2019; 12: 20. Published online 2019 Apr 2. doi: 10.1186/s13072-019-0266-9
PMCID:
PMC6444878
AbstractArticlePDF–3.8M
20.
KDM5B Promotes Drug Resistance by Regulating Melanoma Propagating Cell Subpopulations
Xiaoni Liu, Shang-Min Zhang, Meaghan K. McGeary, Irina Krykbaeva, Ling Lai, Daniel J. Jansen, Stephen C. Kales, Anton Simeonov, Matthew D. Hall, Daniel P. Kelly, Marcus W. Bosenberg, Qin Yan
Mol Cancer Ther. Author manuscript; available in PMC 2020 Mar 1.
Published in final edited form as: Mol Cancer Ther. 2019 Mar; 18(3): 706–717. Published online 2018 Dec 6. doi: 10.1158/1535-7163.MCT-18-0395
PMCID:
PMC6397704
AbstractArticlePDF–1.3M

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