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Select item 110313801.

CRISPR editing of anti-anemia drug target rescues independent preclinical models of retinitis pigmentosa

Nicholas D. Nolan, Xuan Cui, Brian M. Robbings, Aykut Demirkol, Kriti Pandey, Wen-Hsuan Wu, Hannah F. Hu, Laura A. Jenny, Chyuan-Sheng Lin, Daniel T. Hass, Jianhai Du, James B. Hurley, Stephen H. Tsang

Cell Rep Med. 2024 Apr 16; 5(4): 101459. Published online 2024 Mar 21. doi: 10.1016/j.xcrm.2024.101459

PMCID:: PMC11031380

Abstract Article PDF–6.3M

Select item 109608032.

Voluntary exercise preserves visual function and reduces inflammatory response in an adult mouse model of autosomal dominant retinitis pigmentosa

Katie L. Bales, Austin M. Karesh, Kelleigh Hogan, Alicia S. Chacko, GianMarco L. Douglas, Andrew J. Feola, John M. Nickerson, Alyssa Pybus, Levi Wood, Jeffrey H. Boatright, Machelle T. Pardue

Sci Rep. 2024; 14: 6940. Published online 2024 Mar 23. doi: 10.1038/s41598-024-57027-9

PMCID:: PMC10960803

Abstract Article PDF–4.2M

Select item 108734273.

Aggregation of rhodopsin mutants in mouse models of autosomal dominant retinitis pigmentosa

Sreelakshmi Vasudevan, Subhadip Senapati, Maryanne Pendergast, Paul S.–H. Park

Nat Commun. 2024; 15: 1451. Published online 2024 Feb 16. doi: 10.1038/s41467-024-45748-4

PMCID:: PMC10873427

Abstract Article PDF–12M

Select item 107739394.

Super-resolution mapping in rod photoreceptors identifies rhodopsin trafficking through the inner segment plasma membrane as an essential subcellular pathway

Kristen N. Haggerty, Shannon C. Eshelman, Lauren A. Sexton, Emmanuel Frimpong, Leah M. Rogers, Melina A. Agosto, Michael A. Robichaux

PLoS Biol. 2024 Jan; 22(1): e3002467. Published online 2024 Jan 8. doi: 10.1371/journal.pbio.3002467

PMCID:: PMC10773939

Abstract Article PDF–8.1M

Select item 107114825.

Maf1 controls retinal neuron number by both RNA Pol III- and Pol II-dependent mechanisms

Yifei Li, Dongchang Xiao, Haiqiao Chen, X.F. Steven Zheng, Mengqing Xiang

iScience. 2023 Dec 15; 26(12): 108544. Published online 2023 Nov 23. doi: 10.1016/j.isci.2023.108544

PMCID:: PMC10711482

Abstract Article PDF–9.9M

Select item 105848186.

mRNA trans-splicing dual AAV vectors for (epi)genome editing and gene therapy

Lisa Maria Riedmayr, Klara Sonnie Hinrichsmeyer, Stefan Bernhard Thalhammer, David Manuel Mittas, Nina Karguth, Dina Yehia Otify, Sybille Böhm, Valentin Johannes Weber, Michael David Bartoschek, Victoria Splith, Manuela Brümmer, Raphael Ferreira, Nanda Boon, Gabriele Maria Wögenstein, Christian Grimm, Jan Wijnholds, Verena Mehlfeld, Stylianos Michalakis, Stefanie Fenske, Martin Biel, Elvir Becirovic

Nat Commun. 2023; 14: 6578. Published online 2023 Oct 18. doi: 10.1038/s41467-023-42386-0

PMCID:: PMC10584818

Abstract Article PDF–2.9M

Select item 105436437.

Mettl14-mediated m⁶A modification ensures the cell-cycle progression of late-born retinal progenitor cells

Liang Li, Yue Sun, Alexander E. Davis, Sahil H. Shah, Lobna K. Hamed, Man-Ru Wu, Cheng-Hui Lin, Jun B. Ding, Sui Wang

Cell Rep. Author manuscript; available in PMC 2023 Oct 2.

Published in final edited form as: Cell Rep. 2023 Jun 27; 42(6): 112596. Published online 2023 Jun 1. doi: 10.1016/j.celrep.2023.112596

PMCID:: PMC10543643

Abstract Article PDF–3.9M

Select item 105044868.

Highly sensitive visual restoration and protection via ectopic expression of chimeric rhodopsin in mice

Yusaku Katada, Kazuho Yoshida, Naho Serizawa, Deokho Lee, Kenta Kobayashi, Kazuno Negishi, Hideyuki Okano, Hideki Kandori, Kazuo Tsubota, Toshihide Kurihara

iScience. 2023 Oct 20; 26(10): 107716. Published online 2023 Aug 25. doi: 10.1016/j.isci.2023.107716

PMCID:: PMC10504486

Abstract Article PDF–5.1M

Select item 104126419.

Rho enhancers play unexpectedly minor roles in Rhodopsin transcription and rod cell integrity

Chi Sun, Philip A. Ruzycki, Shiming Chen

Sci Rep. 2023; 13: 12899. Published online 2023 Aug 9. doi: 10.1038/s41598-023-39979-6

PMCID:: PMC10412641

Abstract Article PDF–3.3M

Select item 1035468610.

Chromatin remodeler Chd7 regulates photoreceptor development and outer segment length

Laura A. Krueger, Jessica D. Bills, Zun Yi Lim, Jennifer M. Skidmore, Donna M. Martin, Ann C. Morris

Exp Eye Res. Author manuscript; available in PMC 2023 Jul 19.

Published in final edited form as: Exp Eye Res. 2023 Jan; 226: 109299. Published online 2022 Nov 4. doi: 10.1016/j.exer.2022.109299

PMCID:: PMC10354686

Abstract Article PDF–1.3M

Select item 1034868411.

Overexpression of Nfe2l1 increases proteasome activity and delays vision loss in a preclinical model of human blindness

Yixiao Wang, Aaron Snell, Frank M. Dyka, Elizabeth R. Colvin, Cristhian Ildefonso, John D. Ash, Ekaterina S. Lobanova

Sci Adv. 2023 Jul; 9(28): eadd5479. Published online 2023 Jul 14. doi: 10.1126/sciadv.add5479

PMCID:: PMC10348684

Abstract Article PDF–2.1M

Select item 1033537512.

Structural abnormalities of retinal pigment epithelial cells in a light‐inducible, rhodopsin mutant mouse

Debora Napoli, Enrica Strettoi

J Anat. 2023 Aug; 243(2): 223–234. Published online 2022 Apr 15. doi: 10.1111/joa.13667

PMCID:: PMC10335375

Abstract Article PDF–8.6M

Select item 1026603813.

Chromophore supply modulates cone function and survival in retinitis pigmentosa mouse models

Yunlu Xue, Xiaomei Sun, Sean K. Wang, Gayle B. Collin, Vladimir J. Kefalov, Constance L. Cepko

Proc Natl Acad Sci U S A. 2023 Jun 6; 120(23): e2217885120. Published online 2023 May 30. doi: 10.1073/pnas.2217885120

PMCID:: PMC10266038

Abstract Article PDF–5.5M

Select item 1021025914.

Jarid2 promotes temporal progression of retinal progenitors via repression of Foxp1

Jianmin Zhang, Jacqueline M. Roberts, Fei Chang, Joon Schwakopf, Monica L. Vetter

Cell Rep. Author manuscript; available in PMC 2023 May 25.

Published in final edited form as: Cell Rep. 2023 Mar 28; 42(3): 112237. Published online 2023 Mar 14. doi: 10.1016/j.celrep.2023.112237

Correction in:: Cell Rep. 2023 Apr 25; 42(4): 112416.

PMCID:: PMC10210259

Abstract Article PDF–4.4M

Select item 1009326915.

Chromatin Remodeling Enzyme Snf2h Is Essential for Retinal Cell Proliferation and Photoreceptor Maintenance

Andrea Kuzelova, Naoko Dupacova, Barbora Antosova, Sweetu Susan Sunny, Zbynek Kozmik, Jr., Jan Paces, Arthur I. Skoultchi, Tomas Stopka, Zbynek Kozmik

Cells. 2023 Apr; 12(7): 1035. Published online 2023 Mar 28. doi: 10.3390/cells12071035

PMCID:: PMC10093269

Abstract Article PDF–21M

Select item 1007669916.

Biphasic expression of thyroid hormone receptor TRβ1 in mammalian retina and anterior ocular tissues

Lily Ng, Hong Liu, Ye Liu, Douglas Forrest

Front Endocrinol (Lausanne) 2023; 14: 1174600. Published online 2023 Mar 23. doi: 10.3389/fendo.2023.1174600

PMCID:: PMC10076699

Abstract Article PDF–17M

Select item 999769417.

Investigating the Role of Rhodopsin F45L Mutation in Mouse Rod Photoreceptor Signaling and Survival

Deepak Poria, Alexander V. Kolesnikov, Tae Jun Lee, David Salom, Krzysztof Palczewski, Vladimir J. Kefalov

eNeuro. 2023 Mar; 10(3): ENEURO.0330-22.2023. Prepublished online 2023 Feb 21. Published online 2023 Mar 2. doi: 10.1523/ENEURO.0330-22.2023

PMCID:: PMC9997694

Abstract Article PDF–2.4M

Select item 998162218.

Visuomotor anomalies in achiasmatic mice expressing a transfer-defective Vax1 mutant

Kwang Wook Min, Namsuk Kim, Jae Hoon Lee, Younghoon Sung, Museong Kim, Eun Jung Lee, Jong-Myeong Kim, Jae-Hyun Kim, Jaeyoung Lee, Wonjin Cho, Jee Myung Yang, Nury Kim, Jaehoon Kim, C. Justin Lee, Young-Gyun Park, Seung-Hee Lee, Han-Woong Lee, Jin Woo Kim

Exp Mol Med. 2023 Feb; 55(2): 385–400. Published online 2023 Feb 3. doi: 10.1038/s12276-023-00930-4

PMCID:: PMC9981622

Abstract Article PDF–7.4M

Select item 991871919.

Galanin receptor 3 - a new pharmacological target in retina degeneration

Joseph T. Ortega, Tanu Parmar, Beata Jastrzebska

Pharmacol Res. Author manuscript; available in PMC 2024 Feb 1.

Published in final edited form as: Pharmacol Res. 2023 Jan 21; 188: 106675. Published online 2023 Jan 21. doi: 10.1016/j.phrs.2023.106675

PMCID:: PMC9918719

Abstract Article PDF–2.8M

Select item 979672820.

Microvesicle release from inner segments of healthy photoreceptors is a conserved phenomenon in mammalian species

Tylor R. Lewis, Sebastien Phan, Keun-Young Kim, Isha Jha, Carson M. Castillo, Jin-Dong Ding, Benjamin S. Sajdak, Dana K. Merriman, Mark H. Ellisman, Vadim Y. Arshavsky

Dis Model Mech. 2022 Nov 1; 15(11): dmm049871. Published online 2022 Nov 23. doi: 10.1242/dmm.049871

PMCID:: PMC9796728

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