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Select item 111962081.

IGFBP7 promotes endothelial cell repair in the recovery phase of acute lung injury

Rui He, Bo Feng, Yuezhou Zhang, Yuqing Li, Daoxing Wang, Linchao Yu

Clin Sci (Lond) 2024 Jul; 138(13): 797–815. Published online 2024 Jun 21. doi: 10.1042/CS20240179

PMCID:: PMC11196208

Abstract Article PDF–10M

Select item 109176602.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 96755563.

DIO3 protects against thyrotoxicosis-derived cranio-encephalic and cardiac congenital abnormalities

M. Elena Martinez, Ilka Pinz, Marilena Preda, Christine R. Norton, Thomas Gridley, Arturo Hernandez

JCI Insight. 2022 Nov 8; 7(21): e161214. Published online 2022 Nov 8. doi: 10.1172/jci.insight.161214

PMCID:: PMC9675556

Abstract Article PDF–3.9M

Select item 78230764.

Genetic association and characterization of FSTL5 in isolated clubfoot

Anas M Khanshour, Yared H Kidane, Julia Kozlitina, Reuel Cornelia, Alexandra Rafipay, Vanessa De Mello, Mitchell Weston, Nandina Paria, Aysha Khalid, Jacqueline T Hecht, Matthew B Dobbs, B Stephens Richards, Neil Vargesson, F Kent Hamra, Megan Wilson, Carol Wise, Christina A Gurnett, Jonathan J Rios

Hum Mol Genet. 2020 Nov 15; 29(22): 3717–3728. Published online 2020 Oct 26. doi: 10.1093/hmg/ddaa236

PMCID:: PMC7823076

Abstract Article PDF–1.0M

Select item 70463085.

IGFBP7 acts as a negative regulator of RANKL‐induced osteoclastogenesis and oestrogen deficiency‐induced bone loss

Chenyi Ye, Weiduo Hou, Mo Chen, Jinwei Lu, Erman Chen, Lan Tang, Kai Hang, Qianhai Ding, Yan Li, Wei Zhang, Rongxin He

Cell Prolif. 2020 Feb; 53(2): e12752. Published online 2019 Dec 30. doi: 10.1111/cpr.12752

PMCID:: PMC7046308

Abstract Article PDF–2.7M

Select item 69833576.

MS/MS in silico subtraction-based proteomic profiling as an approach to facilitate disease gene discovery: application to lens development and cataract

Sandeep Aryal, Deepti Anand, Francisco G. Hernandez, Bailey A. T. Weatherbee, Hongzhan Huang, Ashok P. Reddy, Phillip A. Wilmarth, Larry L. David, Salil A. Lachke

Hum Genet. Author manuscript; available in PMC 2021 Feb 1.

Published in final edited form as: Hum Genet. 2020 Feb; 139(2): 151–184. Published online 2019 Dec 3. doi: 10.1007/s00439-019-02095-5

PMCID:: PMC6983357

Abstract Article PDF–3.8M

Select item 69109267.

Molecular determinants of nephron vascular specialization in the kidney

David M. Barry, Elizabeth A. McMillan, Balvir Kunar, Raphael Lis, Tuo Zhang, Tyler Lu, Edward Daniel, Masataka Yokoyama, Jesus M. Gomez-Salinero, Angara Sureshbabu, Ondine Cleaver, Annarita Di Lorenzo, Mary E. Choi, Jenny Xiang, David Redmond, Sina Y. Rabbany, Thangamani Muthukumar, Shahin Rafii

Nat Commun. 2019; 10: 5705. Published online 2019 Dec 13. doi: 10.1038/s41467-019-12872-5

PMCID:: PMC6910926

Abstract Article PDF–6.4M

Select item 68647138.

Eleutheroside B Protects against Acute Kidney Injury by Activating IGF Pathway

Hongmei Zang, Qin Yang, Jun Li

Molecules. 2019 Nov; 24(21): 3876. Published online 2019 Oct 28. doi: 10.3390/molecules24213876

PMCID:: PMC6864713

Abstract Article PDF–3.9M

Select item 63298319.

Single-cell transcriptomic analysis of mouse neocortical development

Lipin Loo, Jeremy M. Simon, Lei Xing, Eric S. McCoy, Jesse K. Niehaus, Jiami Guo, E. S. Anton, Mark J. Zylka

Nat Commun. 2019; 10: 134. Published online 2019 Jan 11. doi: 10.1038/s41467-018-08079-9

PMCID:: PMC6329831

Abstract Article PDF–3.6M

Select item 619212110.

Essential roles of mitochondrial biogenesis regulator Nrf1 in retinal development and homeostasis

Takae Kiyama, Ching-Kang Chen, Steven W Wang, Ping Pan, Zhenlin Ju, Jing Wang, Shinako Takada, William H Klein, Chai-An Mao

Mol Neurodegener. 2018; 13: 56. Published online 2018 Oct 17. doi: 10.1186/s13024-018-0287-z

PMCID:: PMC6192121

Abstract Article PDF–12M

Select item 589428011.

IGFBP7 Deletion Promotes Hepatocellular Carcinoma

Maaged Akiel, Chunqing Guo, Xia Li, Devaraja Rajasekaran, Rachel G. Mendoza, Chadia L. Robertson, Nidhi Jariwala, Fang Yuan, Mark A. Subler, Jolene Windle, Dawn K. Garcia, Zhao Lai, Hung-I Harry Chen, Yidong Chen, Shah Giashuddin, Paul B. Fisher, Xiang-Yang Wang, Devanand Sarkar

Cancer Res. Author manuscript; available in PMC 2018 Aug 1.

Published in final edited form as: Cancer Res. 2017 Aug 1; 77(15): 4014–4025. Published online 2017 Jun 15. doi: 10.1158/0008-5472.CAN-16-2885

PMCID:: PMC5894280

Abstract Article PDF–2.9M

Select item 576500512.

Lack of Fgf18 causes abnormal clustering of motor nerve terminals at the neuromuscular junction with reduced acetylcholine receptor clusters

Kenyu Ito, Bisei Ohkawara, Hideki Yagi, Hiroaki Nakashima, Mikito Tsushima, Kyotaro Ota, Hiroyuki Konishi, Akio Masuda, Shiro Imagama, Hiroshi Kiyama, Naoki Ishiguro, Kinji Ohno

Sci Rep. 2018; 8: 434. Published online 2018 Jan 11. doi: 10.1038/s41598-017-18753-5

PMCID:: PMC5765005

Abstract Article PDF–7.5M

Select item 549749513.

Molecular checkpoint decisions made by subverted vascular niche transform indolent tumor cells into chemoresistant cancer stem cells

Zhongwei Cao, Joseph M Scandura, Giorgio G. Inghirami, Koji Shido, Bi-Sen Ding, Shahin Rafii

Cancer Cell. Author manuscript; available in PMC 2017 Jul 5.

Published in final edited form as: Cancer Cell. 2017 Jan 9; 31(1): 110–126. Published online 2016 Dec 15. doi: 10.1016/j.ccell.2016.11.010

PMCID:: PMC5497495

Abstract Article PDF–5.0M

Select item 529582114.

High-throughput discovery of novel developmental phenotypes

Mary E. Dickinson, Ann M. Flenniken, Xiao Ji, Lydia Teboul, Michael D. Wong, Jacqueline K. White, Terrence F. Meehan, Wolfgang J. Weninger, Henrik Westerberg, Hibret Adissu, Candice N. Baker, Lynette Bower, James M. Brown, L. Brianna Caddle, Francesco Chiani, Dave Clary, James Cleak, Mark J. Daly, James M. Denegre, Brendan Doe, Mary E. Dolan, Sarah M. Edie, Helmut Fuchs, Valerie Gailus-Durner, Antonella Galli, Alessia Gambadoro, Juan Gallegos, Shiying Guo, Neil R. Horner, Chih-wei Hsu, Sara J. Johnson, Sowmya Kalaga, Lance C. Keith, Louise Lanoue, Thomas N. Lawson, Monkol Lek, Manuel Mark, Susan Marschall, Jeremy Mason, Melissa L. McElwee, Susan Newbigging, Lauryl M.J. Nutter, Kevin A. Peterson, Ramiro Ramirez-Solis, Douglas J. Rowland, Edward Ryder, Kaitlin E. Samocha, John R. Seavitt, Mohammed Selloum, Zsombor Szoke-Kovacs, Masaru Tamura, Amanda G Trainor, Ilinca Tudose, Shigeharu Wakana, Jonathan Warren, Olivia Wendling, David B. West, Leeyean Wong, Atsushi Yoshiki, The International Mouse Phenotyping Consortium, Daniel G. MacArthur, Glauco P. Tocchini-Valentini, Xiang Gao, Paul Flicek, Allan Bradley, William C. Skarnes, Monica J. Justice, Helen E. Parkinson, Mark Moore, Sara Wells, Robert E. Braun, Karen L. Svenson, Martin Hrabe de Angelis, Yann Herault, Tim Mohun, Ann-Marie Mallon, R. Mark Henkelman, Steve D.M. Brown, David J. Adams, K.C. Kent Lloyd, Colin McKerlie, Arthur L. Beaudet, Maja Bucan, Stephen A. Murray

Nature. Author manuscript; available in PMC 2017 Mar 14.

Published in final edited form as: Nature. 2016 Sep 22; 537(7621): 508–514. Published online 2016 Sep 14. doi: 10.1038/nature19356

Correction in:: Nature. 2017 Nov 16; 551(7680): 398.

PMCID:: PMC5295821

Abstract Article PDF–3.0M

Select item 522315915.

Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression

Alexandra Naba, Karl R. Clauser, D. R. Mani, Steven A. Carr, Richard O. Hynes

Sci Rep. 2017; 7: 40495. Published online 2017 Jan 10. doi: 10.1038/srep40495

PMCID:: PMC5223159

Abstract Article PDF–2.3M

Select item 512232316.

The FOXG1/FOXO/SMAD network balances proliferation and differentiation of cortical progenitors and activates Kcnh3 expression in mature neurons

Riccardo Vezzali, Stefan Christopher Weise, Nicole Hellbach, Venissa Machado, Stefanie Heidrich, Tanja Vogel

Oncotarget. 2016 Jun 21; 7(25): 37436–37455. Published online 2016 May 21. doi: 10.18632/oncotarget.9545

PMCID:: PMC5122323

Abstract Article PDF–9.5M

Select item 511204117.

Mesenchymal Stromal Cells Mitigate Experimental Colitis via Insulin-like Growth Factor Binding Protein 7-mediated Immunosuppression

Yan Liao, Junxia Lei, Muyun Liu, Wanwen Lin, Dongxi Hong, Ying Tuo, Mei Hua Jiang, Huimin Xia, Maosheng Wang, Weijun Huang, Andy Peng Xiang

Mol Ther. 2016 Oct; 24(10): 1860–1872. Prepublished online 2016 Jul 9. Published online 2016 Aug 9. doi: 10.1038/mt.2016.140

PMCID:: PMC5112041

Abstract Article PDF–4.1M

Select item 458728618.

Spatiotemporal regulation of GLI target genes in the mammalian limb bud

Jordan P. Lewandowski, Fang Du, Shilu Zhang, Marian B. Powell, Kristin N. Falkenstein, Hongkai Ji, Steven A. Vokes

Dev Biol. Author manuscript; available in PMC 2016 Oct 1.

Published in final edited form as: Dev Biol. 2015 Oct 1; 406(1): 92–103. Published online 2015 Jul 31. doi: 10.1016/j.ydbio.2015.07.022

PMCID:: PMC4587286

Abstract Article PDF–2.0M

Select item 448913319.

FOXL2 modulates cartilage, skeletal development and IGF1-dependent growth in mice

Mara Marongiu, Loredana Marcia, Emanuele Pelosi, Mario Lovicu, Manila Deiana, Yonqing Zhang, Alessandro Puddu, Angela Loi, Manuela Uda, Antonino Forabosco, David Schlessinger, Laura Crisponi

BMC Dev Biol. 2015; 15: 27. Published online 2015 Jul 2. doi: 10.1186/s12861-015-0072-y

PMCID:: PMC4489133

Abstract Article PDF–3.2M

Select item 431955920.

A high resolution spatiotemporal atlas of gene expression of the developing mouse brain

Carol L. Thompson, Lydia Ng, Vilas Menon, Salvador Martinez, Chang-Kyu Lee, Katie Glattfelder, Susan M. Sunkin, Alex Henry, Christopher Lau, Chinh Dang, Raquel Garcia-Lopez, Almudena Martinez-Ferre, Ana Pombero, John L.R. Rubenstein, Wayne B. Wakeman, John Hohmann, Nick Dee, Andrew J. Sodt, Rob Young, Kimberly Smith, Thuc-Nghi Nguyen, Jolene Kidney, Leonard Kuan, Andreas Jeromin, Ajamete Kaykas, Jeremy Miller, Damon Page, Geri Orta, Amy Bernard, Zackery Riley, Simon Smith, Paul Wohnoutka, Mike Hawrylycz, Luis Puelles, Allan R. Jones

Neuron. Author manuscript; available in PMC 2015 Jul 16.

Published in final edited form as: Neuron. 2014 Jul 16; 83(2): 309–323. Published online 2014 Jun 19. doi: 10.1016/j.neuron.2014.05.033

PMCID:: PMC4319559

Abstract Article PDF–3.0M

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