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Items: 1 to 20 of 125

1.
CD38 Deficiency Protects Mouse Retinal Ganglion Cells Through Activating the NAD+/Sirt1 Pathway in Ischemia-Reperfusion and Optic Nerve Crush Models
Yulian Pang, Haijian Hu, Ke Xu, Ting Cao, Zhiruo Wang, Jiahe Nie, Haina Zheng, Hongdou Luo, Feifei Wang, Chan Xiong, Ke-Yu Deng, Hong-Bo Xin, Xu Zhang
Invest Ophthalmol Vis Sci. 2024 May; 65(5): 36. Published online 2024 May 22. doi: 10.1167/iovs.65.5.36
PMCID:
PMC11127494
AbstractArticlePDF–9.9M
2.
Smooth-Muscle-Cell-Specific Deletion of CD38 Protects Mice from AngII-Induced Abdominal Aortic Aneurysm through Inhibiting Vascular Remodeling
Zhen-Ping Yu, Yi-Kai Wang, Xiao-Yu Wang, Li-Na Gong, Hui-Lan Tan, Mei-Xiu Jiang, Ling-Fang Wang, Guan-Hui Yu, Ke-Yu Deng, Hong-Bo Xin
Int J Mol Sci. 2024 Apr; 25(8): 4356. Published online 2024 Apr 15. doi: 10.3390/ijms25084356
PMCID:
PMC11049988
AbstractArticlePDF–4.1M
3.
CD38 promotes hematopoietic stem cell dormancy
Liliia Ibneeva, Sumeet Pal Singh, Anupam Sinha, Sema Elif Eski, Rebekka Wehner, Luise Rupp, Iryna Kovtun, Juan Alberto Pérez-Valencia, Alexander Gerbaulet, Susanne Reinhardt, Manja Wobus, Malte von Bonin, Jaime Sancho, Frances Lund, Andreas Dahl, Marc Schmitz, Martin Bornhäuser, Triantafyllos Chavakis, Ben Wielockx, Tatyana Grinenko
PLoS Biol. 2024 Feb; 22(2): e3002517. Published online 2024 Feb 29. doi: 10.1371/journal.pbio.3002517
PMCID:
PMC10931502
AbstractArticlePDF–3.7M
4.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
5.
NADase CD38 is a key determinant of ovarian aging
Qingling Yang, Wenhui Chen, Luping Cong, Mengchen Wang, Hui Li, Huan Wang, Xiaoyan Luo, Jing Zhu, Xinxin Zeng, Zhenye Zhu, Yining Xu, Min Lei, Yanqing Zhao, Chenlu Wei, Yingpu Sun
Nat Aging. 2024; 4(1): 110–128. Published online 2023 Dec 21. doi: 10.1038/s43587-023-00532-9
PMCID:
PMC10798903
AbstractArticlePDF–12M
6.
CD38 Deficiency Alleviates Diabetic Cardiomyopathy by Coordinately Inhibiting Pyroptosis and Apoptosis
Ling-Fang Wang, Qian Li, Ke Wen, Qi-Hang Zhao, Ya-Ting Zhang, Jia-Le Zhao, Qi Ding, Xiao-Hui Guan, Yun-Fei Xiao, Ke-Yu Deng, Hong-Bo Xin
Int J Mol Sci. 2023 Nov; 24(21): 16008. Published online 2023 Nov 6. doi: 10.3390/ijms242116008
PMCID:
PMC10650707
AbstractArticlePDF–3.6M
7.
CD38 regulates ovarian function and fecundity via NAD+ metabolism
Rosalba Perrone, Prasanna Vadhana Ashok Kumaar, Lauren Haky, Cosmo Hahn, Rebeccah Riley, Julia Balough, Giuliana Zaza, Bikem Soygur, Kaitlyn Hung, Leandro Prado, Herbert G. Kasler, Ritesh Tiwari, Hiroyuki Matsui, Genesis Vega Hormazabal, Indra Heckenbach, Morten Scheibye-Knudsen, Francesca E. Duncan, Eric Verdin
iScience. 2023 Oct 20; 26(10): 107949. Published online 2023 Sep 16. doi: 10.1016/j.isci.2023.107949
PMCID:
PMC10562803
AbstractArticlePDF–7.0M
8.
Remission of social behavior impairment by oral administration of a precursor of NAD in CD157, but not in CD38, knockout mice
Maria Gerasimenko, Haruhiro Higashida
Front Immunol. 2023; 14: 1166609. Published online 2023 May 4. doi: 10.3389/fimmu.2023.1166609
PMCID:
PMC10192747
AbstractArticlePDF–2.1M
9.
Cell-Intrinsic CD38 Expression Sustains Exhausted CD8+ T Cells by Regulating Their Survival and Metabolism during Chronic Viral Infection
Julia M. DeRogatis, Emily N. Neubert, Karla M. Viramontes, Monique L. Henriquez, Dequina A. Nicholas, Roberto Tinoco
J Virol. 2023 Apr; 97(4): e00225-23. Published online 2023 Apr 11. doi: 10.1128/jvi.00225-23
PMCID:
PMC10134879
AbstractArticlePDF–4.0M
10.
Oxidative degradation of dihydrofolate reductase increases CD38-mediated ferroptosis susceptibility
Yingying Ma, Meiqi Yi, Weixuan Wang, Xiaohui Liu, Qingtao Wang, Chongdong Liu, Yuling Chen, Haiteng Deng
Cell Death Dis. 2022 Nov; 13(11): 944. Published online 2022 Nov 9. doi: 10.1038/s41419-022-05383-7
PMCID:
PMC9646779
AbstractArticlePDF–3.7M
11.
Extracellular vesicles from pristane-treated CD38-deficient mice express an anti-inflammatory neutrophil protein signature, which reflects the mild lupus severity elicited in these mice
Paula Carrillo-Rodríguez, José-Ángel Robles-Guirado, Adrián Cruz-Palomares, Miguel Ángel Palacios-Pedrero, Elena González-Paredes, Alex Más-Ciurana, Carolina Franco-Herrera, Paloma A. Ruiz-de-Castroviejo-Teba, Antonio Lario, Victoria Longobardo, Laura Montosa-Hidalgo, María M. Pérez-Sánchez-Cañete, María-Mercedes Corzo-Corbera, Sandra Redondo-Sánchez, Ana-Belén Jodar, Francisco J. Blanco, Esther Zumaquero, Ramón Merino, Jaime Sancho, Mercedes Zubiaur
Front Immunol. 2022; 13: 1013236. Published online 2022 Oct 24. doi: 10.3389/fimmu.2022.1013236
PMCID:
PMC9638146
AbstractArticlePDF–21M
12.
CD38 Drives Progress of Osteoarthritis by Affecting Cartilage Homeostasis
Jin‐jin Ma, Jun Ying, Jin‐yu Wang, Tao‐tao Xu, Han‐ting Xia, Hong‐ting Jin, Lu‐wei Xiao, Wen‐jun Shang, Wei‐qian Wang, Jian‐yin Feng
Orthop Surg. 2022 May; 14(5): 946–954. Published online 2022 Apr 20. doi: 10.1111/os.13258
PMCID:
PMC9087467
AbstractArticlePDF–6.3M
13.
CD38‐NADase is a new major contributor to Duchenne muscular dystrophic phenotype
Antoine de Zélicourt, Abdallah Fayssoil, Mbarka Dakouane‐Giudicelli, Isley De Jesus, Ahmed Karoui, Faouzi Zarrouki, Florence Lefebvre, Arnaud Mansart, Jean‐Marie Launay, Jerome Piquereau, Mariana G Tarragó, Marcel Bonay, Anne Forand, Sophie Moog, France Piétri‐Rouxel, Elise Brisebard, Claudia C S Chini, Sonu Kashyap, Matthew J Fogarty, Gary C Sieck, Mathias Mericskay, Eduardo N Chini, Ana Maria Gomez, José‐Manuel Cancela, Sabine de la Porte
EMBO Mol Med. 2022 May; 14(5): e12860. Published online 2022 Mar 17. doi: 10.15252/emmm.202012860
PMCID:
PMC9081905
AbstractArticlePDF–5.2M
14.
CD38 plays an age-related role in cholinergic deregulation of airway smooth muscle contractility
Yan Bai, Alonso G. P. Guedes, Ramaswamy Krishnan, Xingbin Ai
J Allergy Clin Immunol. Author manuscript; available in PMC 2023 May 1.
Published in final edited form as: J Allergy Clin Immunol. 2022 May; 149(5): 1643–1654.e8. Published online 2021 Nov 18. doi: 10.1016/j.jaci.2021.10.033
PMCID:
PMC9081122
AbstractArticlePDF–1.5M
15.
Benefits in cardiac function by CD38 suppression: improvement in NAD+ levels, exercise capacity, heart rate variability and protection against catecholamine induced ventricular arrhythmias
Guillermo Agorrody, Thais R. Peclat, Gonzalo Peluso, Luis A. Gonano, Leonardo Santos, Wim van Schooten, Claudia C. S. Chini, Carlos Escande, Eduardo N. Chini, Paola Contreras
J Mol Cell Cardiol. Author manuscript; available in PMC 2023 May 1.
Published in final edited form as: J Mol Cell Cardiol. 2022 May; 166: 11–22. Published online 2022 Feb 1. doi: 10.1016/j.yjmcc.2022.01.008
PMCID:
PMC9035106
AbstractArticlePDF–1.5M
16.
CD38-mediated Inhibition of Bruton’s Tyrosine Kinase in Macrophages Prevents Endotoxemic Lung Injury
Joseph Farahany, Yoshikazu Tsukasaki, Amitabha Mukhopadhyay, Manish Mittal, Saroj Nepal, Chinnaswamy Tiruppathi, Asrar B. Malik
Am J Respir Cell Mol Biol. 2022 Feb; 66(2): 183–195. Published online 2021 Oct 27. doi: 10.1165/rcmb.2021-0272OC
PMCID:
PMC8845142
AbstractArticlePDF–1.5M
17.
CD38 ecto-enzyme in immune cells is induced during aging regulating NAD+ and NMN levels
Claudia C.S. Chini, Thais R. Peclat, Gina M. Warner, Sonu Kashyap, Jair Machado Espindola-Netto, Guilherme C. de Oliveira, Lilian S. Gomez, Kelly A. Hogan, Mariana G. Tarragó, Amrutesh S. Puranik, Guillermo Agorrody, Katie L. Thompson, Kevin Dang, Starlynn Clarke, Bennett G. Childs, Karina S. Kanamori, Micaela A. Witte, Paola Vidal, Anna L. Kirkland, Marco De Cecco, Karthikeyani Chellappa, Melanie R. McReynolds, Connor Jankowski, Tamara Tchkonia, James L. Kirkland, John M. Sedivy, Jan M. van Deursen, Darren J. Baker, Wim van Schooten, Joshua D. Rabinowitz, Joseph A. Baur, Eduardo N. Chini
Nat Metab. Author manuscript; available in PMC 2022 Jan 11.
Published in final edited form as: Nat Metab. 2020 Nov; 2(11): 1284–1304. Published online 2020 Nov 16. doi: 10.1038/s42255-020-00298-z
PMCID:
PMC8752031
AbstractArticlePDF–6.2M
18.
BST1 regulates nicotinamide riboside metabolism via its glycohydrolase and base-exchange activities
Keisuke Yaku, Sailesh Palikhe, Hironori Izumi, Tomoyuki Yoshida, Keisuke Hikosaka, Faisal Hayat, Mariam Karim, Tooba Iqbal, Yasuhito Nitta, Atsushi Sato, Marie E. Migaud, Katsuhiko Ishihara, Hisashi Mori, Takashi Nakagawa
Nat Commun. 2021; 12: 6767. Published online 2021 Nov 19. doi: 10.1038/s41467-021-27080-3
PMCID:
PMC8604996
AbstractArticlePDF–3.2M
19.
CD38 Correlates with an Immunosuppressive Treg Phenotype in Lupus-Prone Mice
Jocelyn C. Pérez-Lara, Enrique Espinosa, Leopoldo Santos-Argumedo, Héctor Romero-Ramírez, Gabriela López-Herrera, Fabio García-García, Claudia Sandoval-Montes, Vianney Ortiz-Navarrete, Mónica Flores-Muñoz, Juan C. Rodríguez-Alba
Int J Mol Sci. 2021 Nov; 22(21): 11977. Published online 2021 Nov 5. doi: 10.3390/ijms222111977
PMCID:
PMC8584421
AbstractArticlePDF–14M
20.
Critical Role of Astrocyte NAD+ Glycohydrolase in Myelin Injury and Regeneration
Monica R. Langley, Chan-Il Choi, Thais R. Peclat, Yong Guo, Whitney L. Simon, Hyesook Yoon, Laurel Kleppe, Claudia F. Lucchinetti, Claudia C. S. Chini, Eduardo N. Chini, Isobel A. Scarisbrick
J Neurosci. 2021 Oct 13; 41(41): 8644–8667. doi: 10.1523/JNEUROSCI.2264-20.2021
PMCID:
PMC8513702
AbstractArticlePDF–12M

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