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Select item 102901021.

NFIC regulates ribosomal biology and ER stress in pancreatic acinar cells and restrains PDAC initiation

Isidoro Cobo, Sumit Paliwal, Cristina Bodas, Irene Felipe, Júlia Melià-Alomà, Ariadna Torres, Jaime Martínez-Villarreal, Marina Malumbres, Fernando García, Irene Millán, Natalia del Pozo, Joo-Cheol Park, Ray J. MacDonald, Javier Muñoz, Raúl Méndez, Francisco X. Real

Nat Commun. 2023; 14: 3761. Published online 2023 Jun 23. doi: 10.1038/s41467-023-39291-x

PMCID:: PMC10290102

Abstract Article PDF–3.4M

Select item 101214682.

Loss of Fgf9 in mice leads to pancreatic hypoplasia and asplenia

Sophie Patzek, Zhe Liu, Sean de la O, Sean Chang, Lauren E. Byrnes, Xiuqin Zhang, David M. Ornitz, Julie B. Sneddon

iScience. 2023 Apr 21; 26(4): 106500. Published online 2023 Mar 25. doi: 10.1016/j.isci.2023.106500

PMCID:: PMC10121468

Abstract Article PDF–12M

Select item 94823363.

Focal adhesion kinase-mediated signaling controls the onset of pancreatic cell differentiation

Uylissa A. Rodriguez, Shakti Dahiya, Michelle L. Raymond, Chenxi Gao, Christina P. Martins-Cargill, Jon D. Piganelli, George K. Gittes, Jing Hu, Farzad Esni

Development. 2022 Sep 1; 149(17): dev200761. Published online 2022 Sep 9. doi: 10.1242/dev.200761

PMCID:: PMC9482336

Abstract Article

Select item 90128264.

Misfolding-induced chronic pancreatitis in CPA1 N256K mutant mice is unaffected by global deletion of Ddit3/Chop

Balázs Csaba Németh, Alexandra Demcsák, Andrea Geisz, Miklós Sahin-Tóth

Sci Rep. 2022; 12: 6357. Published online 2022 Apr 15. doi: 10.1038/s41598-022-09595-x

PMCID:: PMC9012826

Abstract Article PDF–3.5M

Select item 82828605.

Spatio-temporal expression pattern and role of the tight junction protein MarvelD3 in pancreas development and function

Charlotte Heymans, Ophélie Delcorte, Catherine Spourquet, Mylah Villacorte-Tabelin, Sébastien Dupasquier, Younes Achouri, Siam Mahibullah, Pascale Lemoine, Maria S. Balda, Karl Matter, Christophe E. Pierreux

Sci Rep. 2021; 11: 14519. Published online 2021 Jul 15. doi: 10.1038/s41598-021-93654-2

PMCID:: PMC8282860

Abstract Article PDF–6.6M

Select item 82515626.

Insights into the etiology and physiopathology of MODY5/HNF1B pancreatic phenotype with a mouse model of the human disease

Evans Quilichini, Mélanie Fabre, Christoffer Nord, Thassadite Dirami, Axelle Le Marec, Silvia Cereghini, Raymond C Pasek, Maureen Gannon, Ulf Ahlgren, Cécile Haumaitre

J Pathol. 2021 May; 254(1): 31–45. Published online 2021 Mar 18. doi: 10.1002/path.5629

PMCID:: PMC8251562

Abstract Article PDF–46M

Select item 80344187.

Deoxyhypusine synthase, an essential enzyme for hypusine biosynthesis, is required for proper exocrine pancreas development

Leah R. Padgett, Morgan A. Robertson, Emily K. Anderson‐Baucum, Craig T. Connors, Wenting Wu, Raghavendra G. Mirmira, Teresa L. Mastracci

FASEB J. 2021 May; 35(5): e21473. Published online 2021 Apr 3. doi: 10.1096/fj.201903177R

PMCID:: PMC8034418

Abstract Article PDF–1.5M

Select item 71914668.

Ethanol feeding accelerates pancreatitis progression in CPA1 N256K mutant mice

Anna Orekhova, Andrea Geisz, Miklós Sahin-Tóth

Am J Physiol Gastrointest Liver Physiol. 2020 Apr 1; 318(4): G694–G704. Published online 2020 Mar 2. doi: 10.1152/ajpgi.00007.2020

PMCID:: PMC7191466

Abstract Article

Select item 71908329.

LSD1-mediated enhancer silencing attenuates retinoic acid signalling during pancreatic endocrine cell development

Nicholas K. Vinckier, Nisha A. Patel, Ryan J. Geusz, Allen Wang, Jinzhao Wang, Ileana Matta, Austin R. Harrington, Matthew Wortham, Nichole Wetton, Jianxun Wang, Ulupi S. Jhala, Michael G. Rosenfeld, Christopher W. Benner, Hung-Ping Shih, Maike Sander

Nat Commun. 2020; 11: 2082. Published online 2020 Apr 29. doi: 10.1038/s41467-020-16017-x

PMCID:: PMC7190832

Abstract Article PDF–3.5M

Select item 686847210.

Murine Perinatal β-Cell Proliferation and the Differentiation of Human Stem Cell–Derived Insulin-Expressing Cells Require NEUROD1

Anthony I. Romer, Ruth A. Singer, Lina Sui, Dieter Egli, Lori Sussel

Diabetes. 2019 Dec; 68(12): 2259–2271. Published online 2019 Sep 13. doi: 10.2337/db19-0117

PMCID:: PMC6868472

Abstract Article PDF–2.4M

Select item 670263311.

The Pdx1-Bound Swi/Snf Chromatin Remodeling Complex Regulates Pancreatic Progenitor Cell Proliferation and Mature Islet β-Cell Function

Jason M. Spaeth, Jin-Hua Liu, Daniel Peters, Min Guo, Anna B. Osipovich, Fardin Mohammadi, Nilotpal Roy, Anil Bhushan, Mark A. Magnuson, Matthias Hebrok, Christopher V.E. Wright, Roland Stein

Diabetes. 2019 Sep; 68(9): 1806–1818. Published online 2019 Jun 14. doi: 10.2337/db19-0349

PMCID:: PMC6702633

Abstract Article PDF–2.9M

Select item 666883712.

LATS1/2 suppress NFκB and aberrant EMT initiation to permit pancreatic progenitor differentiation

Caitlin M. Braitsch, D. Berfin Azizoglu, Yadanar Htike, Haley R. Barlow, Ulrike Schnell, Christopher P. Chaney, Thomas J. Carroll, Ben Z. Stanger, Ondine Cleaver

PLoS Biol. 2019 Jul; 17(7): e3000382. Published online 2019 Jul 19. doi: 10.1371/journal.pbio.3000382

PMCID:: PMC6668837

Abstract Article PDF–6.1M

Select item 632684913.

Human CPA1 mutation causes digestive enzyme misfolding and chronic pancreatitis in mice

Eszter Hegyi, Miklós Sahin-Tóth

Gut. Author manuscript; available in PMC 2020 Feb 1.

Published in final edited form as: Gut. 2019 Feb; 68(2): 301–312. Published online 2018 Jul 25. doi: 10.1136/gutjnl-2018-315994

PMCID:: PMC6326849

Abstract Article PDF–2.9M

Select item 610571714.

Endocrine lineage biases arise in temporally distinct endocrine progenitors during pancreatic morphogenesis

Marissa A. Scavuzzo, Matthew C. Hill, Jolanta Chmielowiec, Diane Yang, Jessica Teaw, Kuanwei Sheng, Yuelin Kong, Maria Bettini, Chenghang Zong, James F. Martin, Malgorzata Borowiak

Nat Commun. 2018; 9: 3356. Published online 2018 Aug 22. doi: 10.1038/s41467-018-05740-1