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Select item 99117881.

The AP-1 transcription factor Fosl-2 drives cardiac fibrosis and arrhythmias under immunofibrotic conditions

Mara Stellato, Matthias Dewenter, Michal Rudnik, Amela Hukara, Çagla Özsoy, Florian Renoux, Elena Pachera, Felix Gantenbein, Petra Seebeck, Siim Uhtjaerv, Elena Osto, Daniel Razansky, Karin Klingel, Joerg Henes, Oliver Distler, Przemysław Błyszczuk, Gabriela Kania

Commun Biol. 2023; 6: 161. Published online 2023 Feb 9. doi: 10.1038/s42003-023-04534-6

Correction in:: Commun Biol. 2023; 6: 213.

PMCID:: PMC9911788

Abstract Article PDF–3.5M

Select item 92572612.

Fra-2 Is a Dominant Negative Regulator of Natural Killer Cell Development

Diana Schnoegl, Mathias Hochgerner, Dagmar Gotthardt, Leigh M. Marsh

Front Immunol. 2022; 13: 909270. Published online 2022 Jun 22. doi: 10.3389/fimmu.2022.909270

PMCID:: PMC9257261

Abstract Article PDF–11M

Select item 83278563.

Transcriptional repression by FEZF2 restricts alternative identities of cortical projection neurons

Jeremiah Tsyporin, David Tastad, Xiaokuang Ma, Antoine Nehme, Thomas Finn, Liora Huebner, Guoping Liu, Daisy Gallardo, Amr Makhamreh, Jacqueline M. Roberts, Solomon Katzman, Nenad Sestan, Susan K. McConnell, Zhengang Yang, Shenfeng Qiu, Bin Chen

Cell Rep. Author manuscript; available in PMC 2021 Aug 2.

Published in final edited form as: Cell Rep. 2021 Jun 22; 35(12): 109269. doi: 10.1016/j.celrep.2021.109269

PMCID:: PMC8327856

Abstract Article PDF–4.2M

Select item 83132394.

Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development

Francesco Bedogni, Robert F. Hevner

Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034

PMCID:: PMC8313239

Abstract Article PDF–1.6M

Select item 79176435.

The AP-1 Transcription Factor Fosl-2 Regulates Autophagy in Cardiac Fibroblasts during Myocardial Fibrogenesis

Jemima Seidenberg, Mara Stellato, Amela Hukara, Burkhard Ludewig, Karin Klingel, Oliver Distler, Przemysław Błyszczuk, Gabriela Kania

Int J Mol Sci. 2021 Feb; 22(4): 1861. Published online 2021 Feb 13. doi: 10.3390/ijms22041861

PMCID:: PMC7917643

Abstract Article PDF–4.3M

Select item 77710526.

An IL-27-Driven Transcriptional Network Identifies Regulators of IL-10 Expression across T Helper Cell Subsets

Huiyuan Zhang, Asaf Madi, Nir Yosef, Norio Chihara, Amit Awasthi, Caroline Pot, Conner Lambden, Amitabh Srivastava, Patrick R. Burkett, Jackson Nyman, Elena Christian, Yasaman Etminan, Annika Lee, Helene Stroh, Junrong Xia, Katarzyna Karwacz, Pratiksha I. Thakore, Nandini Acharya, Alexandra Schnell, Chao Wang, Lionel Apetoh, Orit Rozenblatt-Rosen, Ana C. Anderson, Aviv Regev, Vijay K. Kuchroo

Cell Rep. Author manuscript; available in PMC 2020 Dec 29.

Published in final edited form as: Cell Rep. 2020 Nov 24; 33(8): 108433. doi: 10.1016/j.celrep.2020.108433

PMCID:: PMC7771052

Abstract Article PDF–2.9M

Select item 76118427.

Release of Notch activity coordinated by IL-1β signalling confers differentiation plasticity of airway progenitors via Fosl2 during alveolar regeneration

Jinwook Choi, Yu Jin Jang, Catherine Dabrowska, Elhadi Iich, Kelly V. Evans, Helen Hall, Sam M. Janes, Benjamin D. Simons, Bon-Kyoung Koo, Jonghwan Kim, Joo-Hyeon Lee

Nat Cell Biol. Author manuscript; available in PMC 2022 Mar 2.

Published in final edited form as: Nat Cell Biol. 2021 Sep 1; 23(9): 953–966. Published online 2021 Sep 2. doi: 10.1038/s41556-021-00742-6

PMCID:: PMC7611842

Abstract Article PDF–8.4M

Select item 68428698.

Fra-2 negatively regulates postnatal alveolar septation by modulating myofibroblast function

Kazuyuki Tsujino, John T. Li, Tatsuya Tsukui, Xin Ren, Latifa Bakiri, Erwin Wagner, Dean Sheppard

Am J Physiol Lung Cell Mol Physiol. 2017 Nov 1; 313(5): L878–L888. Published online 2017 Aug 17. doi: 10.1152/ajplung.00062.2017

PMCID:: PMC6842869

Abstract Article

Select item 66686819.

Fra-2–expressing macrophages promote lung fibrosis

Alvaro C. Ucero, Latifa Bakiri, Ben Roediger, Masakatsu Suzuki, Maria Jimenez, Pratyusha Mandal, Paola Braghetta, Paolo Bonaldo, Luis Paz-Ares, Coral Fustero-Torre, Pilar Ximenez-Embun, Ana Isabel Hernandez, Diego Megias, Erwin F. Wagner

J Clin Invest. 2019 Aug 1; 129(8): 3293–3309. Published online 2019 Jul 15. doi: 10.1172/JCI125366

PMCID:: PMC6668681

Abstract Article PDF–16M

Select item 659722010.

Transcription factor Fra-1 targets arginase-1 to enhance macrophage-mediated inflammation in arthritis

Nicole Hannemann, Shan Cao, Daniel Eriksson, Anne Schnelzer, Jutta Jordan, Martin Eberhardt, Ulrike Schleicher, Jürgen Rech, Andreas Ramming, Steffen Uebe, Arif Ekici, Juan D. Cañete, Xiaoxiang Chen, Tobias Bäuerle, Julio Vera, Christian Bogdan, Georg Schett, Aline Bozec

J Clin Invest. 2019 Jul 1; 129(7): 2669–2684. Published online 2019 May 28. doi: 10.1172/JCI96832

PMCID:: PMC6597220

Abstract Article PDF–13M

Select item 620645811.

Fra-2 Expression in Osteoblasts Regulates Systemic Inflammation and Lung Injury through Osteopontin

Yubin Luo, Bettina Grötsch, Nicole Hannemann, Maria Jimenez, Natacha Ipseiz, Ozge Uluckan, Nengyu Lin, Georg Schett, Erwin F. Wagner, Aline Bozec

Mol Cell Biol. 2018 Nov 15; 38(22): e00022-18. Prepublished online 2018 Sep 4. Published online 2018 Oct 29. doi: 10.1128/MCB.00022-18

PMCID:: PMC6206458

Abstract Article PDF–3.9M

Select item 613398412.

Fra2 Overexpression in Mice Leads to Non-allergic Asthma Development in an IL-13 Dependent Manner

Anna Gungl, Valentina Biasin, Jochen Wilhelm, Andrea Olschewski, Grazyna Kwapiszewska, Leigh M. Marsh

Front Immunol. 2018; 9: 2018. Published online 2018 Sep 5. doi: 10.3389/fimmu.2018.02018

PMCID:: PMC6133984

Abstract Article PDF–18M

Select item 566564313.

CHIP as a membrane-shuttling proteostasis sensor

Yannick Kopp, Wei-Han Lang, Tobias B Schuster, Adrián Martínez-Limón, Harald F Hofbauer, Robert Ernst, Giulia Calloni, R Martin Vabulas

eLife. 2017; 6: e29388. Published online 2017 Nov 1. doi: 10.7554/eLife.29388

PMCID:: PMC5665643

Abstract Article PDF–2.2M

Select item 564738914.

Transcription Factor CTIP1/ BCL11A Regulates Epidermal Differentiation and Lipid Metabolism During Skin Development

Shan Li, Amy Teegarden, Emily M. Bauer, Jaewoo Choi, Nadia Messaddeq, David A. Hendrix, Gitali Ganguli-Indra, Mark Leid, Arup K. Indra

Sci Rep. 2017; 7: 13427. Published online 2017 Oct 18. doi: 10.1038/s41598-017-13347-7

PMCID:: PMC5647389

Abstract Article PDF–5.2M

Select item 550241915.

Fra-2 regulates B cell development by enhancing IRF4 and Foxo1 transcription

Kenia Ubieta, Mireia Garcia, Bettina Grötsch, Steffen Uebe, Georg F. Weber, Merle Stein, Arif Ekici, Georg Schett, Dirk Mielenz, Aline Bozec

J Exp Med. 2017 Jul 3; 214(7): 2059–2071. doi: 10.1084/jem.20160514

PMCID:: PMC5502419

Abstract Article PDF–2.2M

Select item 462192616.

Brain development is impaired in c-fos −/− mice

Fabiola N. Velazquez, César G. Prucca, Olivier Etienne, Diego S. D'Astolfo, David C. Silvestre, François D. Boussin, Beatriz L. Caputto

Oncotarget. 2015 Jul 10; 6(19): 16883–16901. Published online 2015 Jun 19. doi: 10.18632/oncotarget.4527

PMCID:: PMC4621926

Abstract Article PDF–11M

Select item 431955917.

A high resolution spatiotemporal atlas of gene expression of the developing mouse brain

Carol L. Thompson, Lydia Ng, Vilas Menon, Salvador Martinez, Chang-Kyu Lee, Katie Glattfelder, Susan M. Sunkin, Alex Henry, Christopher Lau, Chinh Dang, Raquel Garcia-Lopez, Almudena Martinez-Ferre, Ana Pombero, John L.R. Rubenstein, Wayne B. Wakeman, John Hohmann, Nick Dee, Andrew J. Sodt, Rob Young, Kimberly Smith, Thuc-Nghi Nguyen, Jolene Kidney, Leonard Kuan, Andreas Jeromin, Ajamete Kaykas, Jeremy Miller, Damon Page, Geri Orta, Amy Bernard, Zackery Riley, Simon Smith, Paul Wohnoutka, Mike Hawrylycz, Luis Puelles, Allan R. Jones

Neuron. Author manuscript; available in PMC 2015 Jul 16.

Published in final edited form as: Neuron. 2014 Jul 16; 83(2): 309–323. Published online 2014 Jun 19. doi: 10.1016/j.neuron.2014.05.033

PMCID:: PMC4319559

Abstract Article PDF–3.0M

Select item 429813418.

Terminal epidermal differentiation is regulated by the interaction of Fra-2/AP-1 with Ezh2 and ERK1/2

Stefanie Wurm, Jisheng Zhang, Juan Guinea-Viniegra, Fernando García, Javier Muñoz, Latifa Bakiri, Elena Ezhkova, Erwin F. Wagner

Genes Dev. 2015 Jan 15; 29(2): 144–156. doi: 10.1101/gad.249748.114

PMCID:: PMC4298134

Abstract Article PDF–2.0M

Select item 402346819.

Regulation of steatohepatitis and PPARγ signaling by distinct AP-1 dimers

Sebastian C. Hasenfuss, Latifa Bakiri, Martin K. Thomsen, Evan G. Williams, Johan Auwerx, Erwin F. Wagner

Cell Metab. Author manuscript; available in PMC 2015 Jan 7.

Published in final edited form as: Cell Metab. 2014 Jan 7; 19(1): 84–95. doi: 10.1016/j.cmet.2013.11.018

PMCID:: PMC4023468

Abstract Article PDF–1.5M

Select item 395032720.

Fra-2/AP-1 controls adipocyte differentiation and survival by regulating PPARγ and hypoxia

J Luther, K Ubieta, N Hannemann, M Jimenez, M Garcia, C Zech, G Schett, E F Wagner, A Bozec

Cell Death Differ. 2014 Apr; 21(4): 655–664. Published online 2014 Jan 24. doi: 10.1038/cdd.2013.198

PMCID:: PMC3950327

Abstract Article PDF–1.5M

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