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Items: 1 to 20 of 106

1.
BRCA1 safeguards genome integrity by activating chromosome asynapsis checkpoint to eliminate recombination-defective oocytes
Long Bai, Peng Li, Yu Xiang, Xiaofei Jiao, Jiyuan Chen, Licun Song, Zhongyang Liang, Yidan Liu, Yimin Zhu, Lin-Yu Lu
Proc Natl Acad Sci U S A. 2024 May 7; 121(19): e2401386121. Published online 2024 May 2. doi: 10.1073/pnas.2401386121
PMCID:
PMC11087798
AbstractArticlePDF–10M
2.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
3.
FIGNL1 AAA+ ATPase remodels RAD51 and DMC1 filaments in pre-meiotic DNA replication and meiotic recombination
Masaru Ito, Asako Furukohri, Kenichiro Matsuzaki, Yurika Fujita, Atsushi Toyoda, Akira Shinohara
Nat Commun. 2023; 14: 6857. Published online 2023 Oct 27. doi: 10.1038/s41467-023-42576-w
PMCID:
PMC10611733
AbstractArticlePDF–5.5M
4.
The proper interplay between the expression of Spo11 splice isoforms and the structure of the pseudoautosomal region promotes XY chromosomes recombination
Teresa Giannattasio, Erika Testa, Monica Faieta, Matteo Lampitto, Daniela Nardozi, Stefano di Cecca, Antonella Russo, Marco Barchi
Cell Mol Life Sci. 2023 Oct; 80(10): 279. Published online 2023 Sep 8. doi: 10.1007/s00018-023-04912-7
PMCID:
PMC10491539
AbstractArticlePDF–4.9M
5.
The RNA-binding protein FUS/TLS interacts with SPO11 and PRDM9 and localize at meiotic recombination hotspots
Teresa Giannattasio, Erika Testa, Ramona Palombo, Lidia Chellini, Flavia Franceschini, Álvaro Crevenna, Petko M. Petkov, Maria Paola Paronetto, Marco Barchi
Cell Mol Life Sci. 2023 Apr; 80(4): 107. Published online 2023 Mar 26. doi: 10.1007/s00018-023-04744-5
PMCID:
PMC10040399
AbstractArticlePDF–2.0M
6.
MRNIP interacts with sex body chromatin to support meiotic progression, spermatogenesis, and male fertility in mice
Samina Kazi, Julio M. Castañeda, Audrey Savolainen, Yiding Xu, Ning Liu, Huanyu Qiao, Ramiro Ramirez‐Solis, Kaori Nozawa, Zhifeng Yu, Martin M. Matzuk, Renata Prunskaite‐Hyyryläinen
FASEB J. 2022 Sep; 36(9): e22479. Published online 2022 Aug 3. doi: 10.1096/fj.202101168RR
PMCID:
PMC9544956
AbstractArticlePDF–9.8M
7.
SCF ubiquitin E3 ligase regulates DNA double-strand breaks in early meiotic recombination
Yongjuan Guan, Huijuan Lin, N Adrian Leu, Gordon Ruthel, Serge Y Fuchs, Luca Busino, Mengcheng Luo, P Jeremy Wang
Nucleic Acids Res. 2022 May 20; 50(9): 5129–5144. Published online 2022 Apr 30. doi: 10.1093/nar/gkac304
PMCID:
PMC9122608
AbstractArticlePDF–13M
8.
RAD51AP2 is required for efficient meiotic recombination between X and Y chromosomes
Hui Ma, Tao Li, Xuefeng Xie, Long Jiang, Jingwei Ye, Chenjia Gong, Hanwei Jiang, Suixing Fan, Huan Zhang, Baolu Shi, Beibei Zhang, Xiaohua Jiang, Yang Li, Jianteng Zhou, Jianze Xu, Xingxia Zhang, Xiaoning Hou, Hao Yin, Yuanwei Zhang, Qinghua Shi
Sci Adv. 2022 Jan; 8(2): eabk1789. Published online 2022 Jan 12. doi: 10.1126/sciadv.abk1789
PMCID:
PMC8754306
AbstractArticlePDF–1.0M
9.
Meiotic Cas9 expression mediates gene conversion in the male and female mouse germline
Alexander J. Weitzel, Hannah A. Grunwald, Ceri Weber, Rimma Levina, Valentino M. Gantz, Stephen M. Hedrick, Ethan Bier, Kimberly L. Cooper
PLoS Biol. 2021 Dec; 19(12): e3001478. Published online 2021 Dec 23. doi: 10.1371/journal.pbio.3001478
PMCID:
PMC8699911
AbstractArticlePDF–1.9M
10.
De novo deletions and duplications at recombination hotspots in mouse germlines
Agnieszka Lukaszewicz, Julian Lange, Scott Keeney, Maria Jasin
Cell. Author manuscript; available in PMC 2022 Nov 24.
Published in final edited form as: Cell. 2021 Nov 24; 184(24): 5970–5984.e18. Published online 2021 Nov 17. doi: 10.1016/j.cell.2021.10.025
PMCID:
PMC8616837
AbstractArticlePDF–2.6M
11.
Meiotic recombination mirrors patterns of germline replication in mice and humans
Florencia Pratto, Kevin Brick, Gang Cheng, Gabriel Lam, Jeffrey M. Cloutier, Daisy Dahiya, Stephen R. Wellard, Philip W. Jordan, R. Daniel Camerini-Otero
Cell. Author manuscript; available in PMC 2022 Aug 5.
Published in final edited form as: Cell. 2021 Aug 5; 184(16): 4251–4267.e20. Published online 2021 Jul 13. doi: 10.1016/j.cell.2021.06.025
PMCID:
PMC8591710
AbstractArticlePDF–3.6M
12.
Epigenetic Dysregulation of Mammalian Male Meiosis Caused by Interference of Recombination and Synapsis
Roberto de la Fuente, Florencia Pratto, Abrahan Hernández-Hernández, Marcia Manterola, Pablo López-Jiménez, Rocío Gómez, Alberto Viera, María Teresa Parra, Anna Kouznetsova, R. Daniel Camerini-Otero, Jesús Page
Cells. 2021 Sep; 10(9): 2311. Published online 2021 Sep 3. doi: 10.3390/cells10092311
PMCID:
PMC8467405
AbstractArticlePDF–12M
13.
A segregating human allele of SPO11 modeled in mice disrupts timing and amounts of meiotic recombination, causing oligospermia and a decreased ovarian reserve
Tina N Tran, John C Schimenti
Biol Reprod. 2019 Aug; 101(2): 347–359. Published online 2019 May 10. doi: 10.1093/biolre/ioz089
PMCID:
PMC8127034
AbstractArticlePDF–3.8M
14.
PRDM9 activity depends on HELLS and promotes local 5-hydroxymethylcytosine enrichment
Yukiko Imai, Mathilde Biot, Julie AJ Clément, Mariko Teragaki, Serge Urbach, Thomas Robert, Frédéric Baudat, Corinne Grey, Bernard de Massy
eLife. 2020; 9: e57117. Published online 2020 Oct 13. doi: 10.7554/eLife.57117
PMCID:
PMC7599071
AbstractArticlePDF–4.4M
15.
Meiotic cohesins mediate initial loading of HORMAD1 to the chromosomes and coordinate SC formation during meiotic prophase
Yasuhiro Fujiwara, Yuki Horisawa-Takada, Erina Inoue, Naoki Tani, Hiroki Shibuya, Sayoko Fujimura, Ryo Kariyazono, Toyonori Sakata, Kunihiro Ohta, Kimi Araki, Yuki Okada, Kei-ichiro Ishiguro
PLoS Genet. 2020 Sep; 16(9): e1009048. Published online 2020 Sep 15. doi: 10.1371/journal.pgen.1009048
PMCID:
PMC7518614
AbstractArticlePDF–4.8M
16.
A missense in HSF2BP causing primary ovarian insufficiency affects meiotic recombination by its novel interactor C19ORF57/BRME1
Natalia Felipe-Medina, Sandrine Caburet, Fernando Sánchez-Sáez, Yazmine B Condezo, Dirk G de Rooij, Laura Gómez-H, Rodrigo Garcia-Valiente, Anne Laure Todeschini, Paloma Duque, Manuel Adolfo Sánchez-Martin, Stavit A Shalev, Elena Llano, Reiner A Veitia, Alberto M Pendás
eLife. 2020; 9: e56996. Published online 2020 Aug 26. doi: 10.7554/eLife.56996
PMCID:
PMC7498267
AbstractArticlePDF–12M
17.
The Configuration of RPA, RAD51, and DMC1 Binding in Meiosis Reveals the Nature of Critical Recombination Intermediates
Anjali Gupta Hinch, Philipp W. Becker, Tao Li, Daniela Moralli, Gang Zhang, Clare Bycroft, Catherine Green, Scott Keeney, Qinghua Shi, Benjamin Davies, Peter Donnelly
Mol Cell. 2020 Aug 20; 79(4): 689–701.e10. doi: 10.1016/j.molcel.2020.06.015
PMCID:
PMC7447979
AbstractArticle
18.
MEIOK21: a new component of meiotic recombination bridges required for spermatogenesis
Yongliang Shang, Tao Huang, Hongbin Liu, Yanlei Liu, Heng Liang, Xiaoxia Yu, Mengjing Li, Binyuan Zhai, Xiao Yang, Yudong Wei, Guoqiang Wang, Zijiang Chen, Shunxin Wang, Liangran Zhang
Nucleic Acids Res. 2020 Jul 9; 48(12): 6624–6639. Published online 2020 May 28. doi: 10.1093/nar/gkaa406
PMCID:
PMC7337969
AbstractArticlePDF–9.8M
19.
vacbThe enigmatic meiotic dense body and its newly discovered component, SCML1, are dispensable for fertility and gametogenesis in mice
Frantzeskos Papanikos, Katrin Daniel, Angelique Ramlal, Ji-Feng Fei, Thomas Kurth, Lukasz Wojtasz, Ihsan Dereli, Jun Fu, Nadine Maiwald, Josef Penninger, Bianca Habermann, Azim Surani, Francis Stewart, Attila Toth
Chromosoma. Author manuscript; available in PMC 2020 Jun 30.
Published in final edited form as: Chromosoma. 2017 Jun 1; 126(3): 399–415. Published online 2016 May 10. doi: 10.1007/s00412-016-0598-1
PMCID:
PMC7326603
AbstractArticlePDF–2.9M
20.
NBS1 is required for SPO11-linked DNA double-strand break repair in male meiosis
Bin Zhang, Zhenghui Tang, Lejun Li, Lin-Yu Lu
Cell Death Differ. 2020 Jul; 27(7): 2176–2190. Published online 2020 Jan 21. doi: 10.1038/s41418-020-0493-4
PMCID:
PMC7308329
AbstractArticlePDF–8.6M

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