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Items: 1 to 20 of 35

1.
Human kallikrein 4 signal peptide induces cytotoxic T cell responses in healthy donors and prostate cancer patients
Ray Wilkinson, Katherine Woods, Rachael D’Rozario, Rebecca Prue, Frank Vari, Melinda Y. Hardy, Ying Dong, Judith A. Clements, Derek N. J. Hart, Kristen J. Radford
Cancer Immunol Immunother. 2012 Feb; 61(2): 169–179. Published online 2011 Aug 27. doi: 10.1007/s00262-011-1095-2
PMCID:
PMC11028920
AbstractArticlePDF–597K
2.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
3.
Crystal structure of the inhibitor-free form of the serine protease kallikrein-4
Blake T. Riley, David E. Hoke, Sheena McGowan, Ashley M. Buckle
Acta Crystallogr F Struct Biol Commun. 2019 Aug 1; 75(Pt 8): 543–546. Published online 2019 Jul 16. doi: 10.1107/S2053230X19009610
PMCID:
PMC6688662
AbstractArticlePDF–575K
4.
A protein scaffold, engineered SPINK2, for generation of inhibitors with high affinity and specificity against target proteases
Daisuke Nishimiya, Yoshirou Kawaguchi, Shiho Kodama, Hatsumi Nasu, Hidenori Yano, Aya Yamaguchi, Masakazu Tamura, Ryuji Hashimoto
Sci Rep. 2019; 9: 11436. Published online 2019 Aug 7. doi: 10.1038/s41598-019-47615-5
PMCID:
PMC6686015
AbstractArticlePDF–1.3M
5.
Characterization of kallikrein-related peptidase 4 (KLK4) mRNA expression in tumor tissue of advanced high-grade serous ovarian cancer patients
Weiwei Gong, Yueyang Liu, Christof Seidl, Tobias Dreyer, Enken Drecoll, Matthias Kotzsch, Holger Bronger, Julia Dorn, Viktor Magdolen
PLoS One. 2019; 14(2): e0212968. Published online 2019 Feb 27. doi: 10.1371/journal.pone.0212968
PMCID:
PMC6392272
AbstractArticlePDF–991K
6.
Crystal structures of the complex of a kallikrein inhibitor from Bauhinia bauhinioides with trypsin and modeling of kallikrein complexes
Mi Li, Jaroslav Srp, Alla Gustchina, Zbigniew Dauter, Michael Mares, Alexander Wlodawer
Acta Crystallogr D Struct Biol. 2019 Jan 1; 75(Pt 1): 56–69. Published online 2019 Jan 7. doi: 10.1107/S2059798318016492
PMCID:
PMC6333282
AbstractArticlePDF–3.3M
7.
Regulation of the adaptation to ER stress by KLF4 facilitates melanoma cell metastasis via upregulating NUCB2 expression
Dongmei Zhang, Jingrong Lin, Yulin Chao, Lu Zhang, Lei Jin, Na Li, Ruiping He, Binbin Ma, Wenzhi Zhao, Chuanchun Han
J Exp Clin Cancer Res. 2018; 37: 176. Published online 2018 Jul 28. doi: 10.1186/s13046-018-0842-z
Correction in:
J Exp Clin Cancer Res. 2021; 40: 385.
PMCID:
PMC6064624
AbstractArticlePDF–5.7M
8.
Kallikrein‐related peptidase 4 induces cancer‐associated fibroblast features in prostate‐derived stromal cells
Thomas Kryza, Lakmali M. Silva, Nathalie Bock, Ruth A. Fuhrman‐Luck, Carson R. Stephens, Jin Gao, Hema Samaratunga, Australian Prostate Cancer BioResource, Mitchell G. Lawrence, John D. Hooper, Ying Dong, Gail P. Risbridger, Judith A. Clements
Mol Oncol. 2017 Oct; 11(10): 1307–1329. Published online 2017 Aug 10. doi: 10.1002/1878-0261.12075
PMCID:
PMC5623815
AbstractArticlePDF–1.2M
9.
Architecture of the human interactome defines protein communities and disease networks
Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper
Nature. Author manuscript; available in PMC 2017 Nov 17.
Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366
PMCID:
PMC5531611
AbstractArticlePDF–2.7M
10.
Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing
Teng Fei, Yiwen Chen, Tengfei Xiao, Wei Li, Laura Cato, Peng Zhang, Maura B. Cotter, Michaela Bowden, Rosina T. Lis, Shuang G. Zhao, Qiu Wu, Felix Y. Feng, Massimo Loda, Housheng Hansen He, X. Shirley Liu, Myles Brown
Proc Natl Acad Sci U S A. 2017 Jun 27; 114(26): E5207–E5215. Published online 2017 Jun 13. doi: 10.1073/pnas.1617467114
PMCID:
PMC5495225
AbstractArticlePDF–1.3M
11.
Direct and indirect mechanisms of KLK4 inhibition revealed by structure and dynamics
Blake T. Riley, Olga Ilyichova, Mauricio G. S. Costa, Benjamin T. Porebski, Simon J. de Veer, Joakim E. Swedberg, Itamar Kass, Jonathan M. Harris, David E. Hoke, Ashley M. Buckle
Sci Rep. 2016; 6: 35385. Published online 2016 Oct 21. doi: 10.1038/srep35385
PMCID:
PMC5073354
AbstractArticlePDF–2.5M
12.
Maturation Stage Enamel Malformations in Amtn and Klk4 Null Mice
Stephanie M. Nunez, Yong-Hee P. Chun, Bernhard Ganss, Yuanyuan Hu, Amelia S Richardson, James E. Schmitz, Roberto Fajardo, Jie Yang, Jan C-C. Hu, James P. Simmer
Matrix Biol. Author manuscript; available in PMC 2017 May 1.
Published in final edited form as: Matrix Biol. 2016 May-Jul; 52-54: 219–233. Published online 2015 Nov 24. doi: 10.1016/j.matbio.2015.11.007
PMCID:
PMC4875837
AbstractArticlePDF–5.3M
13.
hORFeome v3.1: A resource of human open reading frames representing over 10,000 human genes
Philippe Lamesch, Ning Li, Stuart Milstein, Changyu Fan, Tong Hao, Gabor Szabo, Zhenjun Hu, Kavitha Venkatesan, Graeme Bethel, Paul Martin, Jane Rogers, Stephanie Lawlor, Stuart McLaren, Amélie Dricot, Heather Borick, Michael E. Cusick, Jean Vandenhaute, Ian Dunham, David E. Hill, Marc Vidal
Genomics. 2007 Mar; 89(3): 307–315. doi: 10.1016/j.ygeno.2006.11.012
PMCID:
PMC4647941
AbstractArticle
14.
The BioPlex Network: A Systematic Exploration of the Human Interactome
Edward L. Huttlin, Lily Ting, Raphael J. Bruckner, Fana Gebreab, Melanie P. Gygi, John Szpyt, Stanley Tam, Gabriela Zarraga, Greg Colby, Kurt Baltier, Rui Dong, Virginia Guarani, Laura Pontano Vaites, Alban Ordureau, Ramin Rad, Brian K. Erickson, Martin Wühr, Joel Chick, Bo Zhai, Deepak Kolippakkam, Julian Mintseris, Robert A. Obar, Tim Harris, Spyros Artavanis-Tsakonas, Mathew E. Sowa, Pietro DeCamilli, Joao A. Paulo, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2016 Jul 16.
Published in final edited form as: Cell. 2015 Jul 16; 162(2): 425–440. doi: 10.1016/j.cell.2015.06.043
PMCID:
PMC4617211
AbstractArticlePDF–2.2M
15.
Clinical Significance of Kallikrein-related-peptidase-4 in Oral Cancer
PETROS PAPAGERAKIS, GIUSEPPE PANNONE, LI ZHENG, MARIA ATHANASSIOU-PAPAEFTHYMIOU, YASHUO YAMAKOSHI, HOWARD STAN McGUFF, OMAR SHKEIR, KONSTANTINOS GHIRTIS, SILVANA PAPAGERAKIS
Anticancer Res. Author manuscript; available in PMC 2015 Sep 21.
Published in final edited form as: Anticancer Res. 2015 Apr; 35(4): 1861–1866.
PMCID:
PMC4577232
AbstractArticlePDF–786K
16.
A proteome-scale map of the human interactome network
Thomas Rolland, Murat Taşan, Benoit Charloteaux, Samuel J. Pevzner, Quan Zhong, Nidhi Sahni, Song Yi, Irma Lemmens, Celia Fontanillo, Roberto Mosca, Atanas Kamburov, Susan D. Ghiassian, Xinping Yang, Lila Ghamsari, Dawit Balcha, Bridget E. Begg, Pascal Braun, Marc Brehme, Martin P. Broly, Anne-Ruxandra Carvunis, Dan Convery-Zupan, Roser Corominas, Jasmin Coulombe-Huntington, Elizabeth Dann, Matija Dreze, Amélie Dricot, Changyu Fan, Eric Franzosa, Fana Gebreab, Bryan J. Gutierrez, Madeleine F. Hardy, Mike Jin, Shuli Kang, Ruth Kiros, Guan Ning Lin, Katja Luck, Andrew MacWilliams, Jörg Menche, Ryan R. Murray, Alexandre Palagi, Matthew M. Poulin, Xavier Rambout, John Rasla, Patrick Reichert, Viviana Romero, Elien Ruyssinck, Julie M. Sahalie, Annemarie Scholz, Akash A. Shah, Amitabh Sharma, Yun Shen, Kerstin Spirohn, Stanley Tam, Alexander O. Tejeda, Shelly A. Wanamaker, Jean-Claude Twizere, Kerwin Vega, Jennifer Walsh, Michael E. Cusick, Yu Xia, Albert-László Barabási, Lilia M. Iakoucheva, Patrick Aloy, Javier De Las Rivas, Jan Tavernier, Michael A. Calderwood, David E. Hill, Tong Hao, Frederick P. Roth, Marc Vidal
Cell. Author manuscript; available in PMC 2015 Nov 20.
Published in final edited form as: Cell. 2014 Nov 20; 159(5): 1212–1226. doi: 10.1016/j.cell.2014.10.050
PMCID:
PMC4266588
AbstractArticlePDF–3.1M
17.
A Possible Mechanism behind Autoimmune Disorders Discovered By Genome-Wide Linkage and Association Analysis in Celiac Disease
Malin Östensson, Caroline Montén, Jonas Bacelis, Audur H. Gudjonsdottir, Svetlana Adamovic, Johan Ek, Henry Ascher, Elisabet Pollak, Henrik Arnell, Lars Browaldh, Daniel Agardh, Jan Wahlström, Staffan Nilsson, Åsa Torinsson-Naluai
PLoS One. 2013; 8(8): e70174. Published online 2013 Aug 2. doi: 10.1371/journal.pone.0070174
PMCID:
PMC3732286
AbstractArticlePDF–1.7M
18.
Susceptibility Loci Associated with Prostate Cancer Progression and Mortality
David J. Gallagher, Joseph Vijai, Angel M. Cronin, Jasmine Bhatia, Andrew J. Vickers, Mia M. Gaudet, Samson Fine, Victor Reuter, Howard I. Scher, Christer Halldén, Ana Dutra-Clarke, Robert J. Klein, Peter T. Scardino, James A. Eastham, Hans Lilja, Tomas Kirchhoff, Kenneth Offit
Clin Cancer Res. Author manuscript; available in PMC 2013 Aug 2.
Published in final edited form as: Clin Cancer Res. 2010 May 15; 16(10): 2819–2832. Published online 2010 May 11. doi: 10.1158/1078-0432.CCR-10-0028
PMCID:
PMC3732009
AbstractArticlePDF–683K
19.
Molecular circuit involving KLK4 integrates androgen and mTOR signaling in prostate cancer
Yang Jin, Su Qu, Martina Tesikova, Ling Wang, Alexandr Kristian, Gunhild M. Mælandsmo, Haiying Kong, Tianzhou Zhang, Carmen Jerónimo, Manuel R. Teixeira, Erkan Yuca, Ibrahim Tekedereli, Kivanc Gorgulu, Neslihan Alpay, Anil K. Sood, Gabriel Lopez-Berestein, Håvard E. Danielsen, Bulent Ozpolat, Fahri Saatcioglu
Proc Natl Acad Sci U S A. 2013 Jul 9; 110(28): E2572–E2581. Published online 2013 Jun 24. doi: 10.1073/pnas.1304318110
PMCID:
PMC3710885
AbstractArticlePDF–1.3M
20.
Novel KLK4 and MMP20 Mutations Discovered by Whole-exome Sequencing
S.-K. Wang, Y. Hu, J.P. Simmer, F. Seymen, N.M.R.P. Estrella, S. Pal, B.M. Reid, M. Yildirim, M. Bayram, J.D. Bartlett, J.C.-C. Hu
J Dent Res. 2013 Mar; 92(3): 266–271. doi: 10.1177/0022034513475626
PMCID:
PMC3576998
AbstractArticlePDF–496K

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