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Select item 111157961.

The human α₂-plasmin inhibitor: functional characterization of the unique plasmin(ogen)-binding region

Simon S. Gerber, Sofia Lejon, Michael Locher, Johann Schaller

Cell Mol Life Sci. 2010 May; 67(9): 1505–1518. Published online 2010 Jan 29. doi: 10.1007/s00018-010-0264-3

PMCID:: PMC11115796

Abstract Article PDF–439K

Select item 108254912.

Proteoform-Resolved Profiling of Plasminogen Activation Reveals Novel Abundant Phosphorylation Site and Primary N-Terminal Cleavage Site

Dario A.T. Cramer, Victor Yin, Tomislav Caval, Vojtech Franc, Dingyi Yu, Guojie Wu, Gordon Lloyd, Christopher Langendorf, James C. Whisstock, Ruby H.P. Law, Albert J.R. Heck

Mol Cell Proteomics. 2024 Jan; 23(1): 100696. Published online 2023 Dec 13. doi: 10.1016/j.mcpro.2023.100696

PMCID:: PMC10825491

Abstract Article PDF–1.9M

Select item 107707273.

Identification and characterization of calreticulin as a novel plasminogen receptor

Alamelu G. Bharadwaj, Gillian C. Okura, John W. Woods, Erica A. Allen, Victoria A. Miller, Emma Kempster, Mark A. Hancock, Shashi Gujar, Rimantas Slibinskas, David M. Waisman

J Biol Chem. 2024 Jan; 300(1): 105465. Published online 2023 Nov 17. doi: 10.1016/j.jbc.2023.105465

PMCID:: PMC10770727

Abstract Article PDF–2.7M

Select item 107662004.

Plasminogen deficiency suppresses pancreatic ductal adenocarcinoma disease progression

Nayela N. Chowdhury, Yi Yang, Ananya Dutta, Michelle Luo, Zimu Wei, Sara R. Abrahams, Alexey S. Revenko, Fenil Shah, Lindsey A. Miles, Robert J. Parmer, Bas de Laat, Alisa S. Wolberg, James P. Luyendyk, Melissa L. Fishel, Matthew J. Flick

Mol Oncol. 2024 Jan; 18(1): 113–135. Published online 2023 Nov 27. doi: 10.1002/1878-0261.13552

PMCID:: PMC10766200

Abstract Article PDF–16M

Select item 105679515.

A dual role for ERK-1/2 in the regulation of plasmin activity and cell migration in metastatic NSCLC-H1299 cells

Sarah Zeitlmayr, Ditila Cami, Belinda Selmani, Thomas Gudermann, Andreas Breit

Arch Toxicol. 2023; 97(12): 3113–3128. Published online 2023 Sep 15. doi: 10.1007/s00204-023-03600-6

PMCID:: PMC10567951

Abstract Article PDF–1.4M

Select item 105095176.

Increased glutamate in type 2 diabetes in the Korean population is associated with increased plasminogen levels

Hyo Jung Lee, Jeong Won Yeom, Ji Ho Yun, Han Byul Jang, Min‐Gyu Yoo, Hyo‐Jin Kim, Soo Kyung Koo, Hye‐Ja Lee

J Diabetes. 2023 Sep; 15(9): 777–786. Published online 2023 Jun 14. doi: 10.1111/1753-0407.13429

PMCID:: PMC10509517

Abstract Article PDF–3.2M

Select item 103722737.

A Missense Mutation of the Plasminogen Gene in a Japanese Family with Hereditary Angioedema with Normal C1 Inhibitor: Third Family Survey in Asia

Hiromasa Yakushiji, Keiko Yamagami, Chinami Hashimura, Hiromi Iwasaki, Takahiko Horiuchi

Intern Med. 2023 Jul 1; 62(13): 2005–2008. Published online 2022 Nov 23. doi: 10.2169/internalmedicine.0645-22

PMCID:: PMC10372273

Abstract Article PDF–369K

Select item 99635518.

Angiopoietin-like protein 4/8 complex-mediated plasmin generation leads to cleavage of the complex and restoration of LPL activity

Eugene Y. Zhen, Yan Q. Chen, Anna M. Russell, Mariam Ehsani, Robert W. Siegel, Yuewei Qian, Robert J. Konrad

Proc Natl Acad Sci U S A. 2023 Feb 14; 120(7): e2214081120. Published online 2023 Feb 10. doi: 10.1073/pnas.2214081120

PMCID:: PMC9963551

Abstract Article PDF–2.0M

Select item 99138029.

The Role of the Plasminogen/Plasmin System in Inflammation of the Oral Cavity

Tetiana Yatsenko, Maksym Skrypnyk, Olga Troyanovska, Morikuni Tobita, Taro Osada, Satoshi Takahashi, Koichi Hattori, Beate Heissig

Cells. 2023 Feb; 12(3): 445. Published online 2023 Jan 30. doi: 10.3390/cells12030445

PMCID:: PMC9913802

Abstract Article PDF–1.0M

Select item 986091510.

Distinguishing Plasmin-Generating Microvesicles: Tiny Messengers Involved in Fibrinolysis and Proteolysis

Laurent Plawinski, Audrey Cras, José Rubicel Hernández Lopez, Aurora de la Peña, Angéline Van der Heyden, Catherine Belle, Florence Toti, Eduardo Anglés-Cano

Int J Mol Sci. 2023 Jan; 24(2): 1571. Published online 2023 Jan 13. doi: 10.3390/ijms24021571

PMCID:: PMC9860915

Abstract Article PDF–2.2M

Select item 940645811.

LPAL2 Suppresses Tumor Growth and Metastasis of Hepatocellular Carcinoma by Modulating MMP9 Expression

Yang-Hsiang Lin, Yu-Chin Liu, Cheng-Yi Chen, Hsiang-Cheng Chi, Meng-Han Wu, Po-Shuan Huang, Cheng-Chih Chang, Tzu-Kang Lin, Chau-Ting Yeh, Kwang-Huei Lin

Cells. 2022 Aug; 11(16): 2610. Published online 2022 Aug 22. doi: 10.3390/cells11162610

PMCID:: PMC9406458

Abstract Article PDF–2.7M

Select item 930295812.

TRPM7 restrains plasmin activity and promotes transforming growth factor-β1 signaling in primary human lung fibroblasts

Sarah Zeitlmayr, Susanna Zierler, Claudia A. Staab-Weijnitz, Alexander Dietrich, Fabienne Geiger, F. David Horgen, Thomas Gudermann, Andreas Breit

Arch Toxicol. 2022; 96(10): 2767–2783. Published online 2022 Jul 21. doi: 10.1007/s00204-022-03342-x

PMCID:: PMC9302958

Abstract Article PDF–1.5M

Select item 927024613.

Plasminogen and plasmin can bind to human T cells and generate truncated CCL21 that increases dendritic cell chemotactic responses

Evert J. Loef, Hilary M. Sheppard, Nigel P. Birch, P. Rod Dunbar

J Biol Chem. 2022 Jul; 298(7): 102112. Published online 2022 Jun 9. doi: 10.1016/j.jbc.2022.102112

PMCID:: PMC9270246

Abstract Article PDF–1.2M

Select item 905883614.

The involvement of Parkin-dependent mitophagy in the anti-cancer activity of Ginsenoside

Xin Sun, Yeting Hong, Yuhan Shu, Caixia Wu, Guiqin Ye, Hanxiao Chen, Hongying Zhou, Ruilan Gao, Jianbin Zhang

J Ginseng Res. 2022 Mar; 46(2): 266–274. Published online 2021 Jul 8. doi: 10.1016/j.jgr.2021.06.009

PMCID:: PMC9058836

Abstract Article PDF–2.9M

Select item 874895815.

EZH2 depletion potentiates MYC degradation inhibiting neuroblastoma and small cell carcinoma tumor formation

Liyuan Wang, Chan Chen, Zemin Song, Honghong Wang, Minghui Ye, Donghai Wang, Wenqian Kang, Hudan Liu, Guoliang Qing

Nat Commun. 2022; 13: 12. Published online 2022 Jan 10. doi: 10.1038/s41467-021-27609-6

PMCID:: PMC8748958

Abstract Article PDF–3.0M

Select item 863324916.

Binding of the kringle‐2 domain of human plasminogen to streptococcal PAM‐type M‐protein causes dissociation of PAM dimers

Olawole Ayinuola, Yetunde A. Ayinuola, Cunjia Qiu, Shaun W. Lee, Victoria A. Ploplis, Francis J. Castellino

Microbiologyopen. 2021 Nov; 10(6): e1252. Published online 2021 Nov 30. doi: 10.1002/mbo3.1252

PMCID:: PMC8633249

Abstract Article PDF–1.3M

Select item 851692217.

Loss of TRIM31 promotes breast cancer progression through regulating K48- and K63-linked ubiquitination of p53

Yafei Guo, Qin Li, Gang Zhao, Jie Zhang, Hang Yuan, Tianyu Feng, Deqiong Ou, Rui Gu, Siqi Li, Kai Li, Ping Lin

Cell Death Dis. 2021 Oct; 12(10): 945. Published online 2021 Oct 14. doi: 10.1038/s41419-021-04208-3

PMCID:: PMC8516922

Abstract Article PDF–8.2M

Select item 834007818.

Low level of plasminogen increases risk for mortality in COVID-19 patients

David Della-Morte, Francesca Pacifici, Camillo Ricordi, Renato Massoud, Valentina Rovella, Stefania Proietti, Mariannina Iozzo, Davide Lauro, Sergio Bernardini, Stefano Bonassi, Nicola Di Daniele

Cell Death Dis. 2021 Aug; 12(8): 773. Published online 2021 Aug 5. doi: 10.1038/s41419-021-04070-3

PMCID:: PMC8340078

Abstract Article PDF–1.1M

Select item 831042919.

Plasmin-mediated cleavage of high-molecular-weight kininogen contributes to acetaminophen-induced acute liver failure

Michael W. Henderson, Erica M. Sparkenbaugh, Shaobin Wang, Anton Ilich, Denis F. Noubouossie, Reiner Mailer, Thomas Renné, Matthew J. Flick, James P. Luyendyk, Zu-Lin Chen, Sidney Strickland, R. Todd Stravitz, Keith R. McCrae, Nigel S. Key, Rafal Pawlinski

Blood. 2021 Jul 22; 138(3): 259–272. Prepublished online 2021 Apr 7. doi: 10.1182/blood.2020006198