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Select item 112627921.

Liver microRNA transcriptome reveals miR-182 as link between type 2 diabetes and fatty liver disease in obesity

Christin Krause, Jan H Britsemmer, Miriam Bernecker, Anna Molenaar, Natalie Taege, Nuria Lopez-Alcantara, Cathleen Geißler, Meike Kaehler, Katharina Iben, Anna Judycka, Jonas Wagner, Stefan Wolter, Oliver Mann, Paul Pfluger, Ingolf Cascorbi, Hendrik Lehnert, Kerstin Stemmer, Sonja C Schriever, Henriette Kirchner

eLife. 2024; 12: RP92075. Published online 2024 Jul 22. doi: 10.7554/eLife.92075

PMCID:: PMC11262792

Abstract Article PDF–5.4M

Select item 109646162.

Low expression of miR-182 caused by DNA hypermethylation accelerates acute lymphocyte leukemia development by targeting PBX3 and BCL2: miR-182 promoter methylation is a predictive marker for hypomethylation agents + BCL2 inhibitor venetoclax

Danyang Li, Yigang Yuan, Chen Meng, Zihan Lin, Min Zhao, Liuzhi Shi, Min Li, Daijiao Ye, Yue Cai, Xiaofei He, Haige Ye, Shujuan Zhou, Haixia Zhou, Shenmeng Gao

Clin Epigenetics. 2024; 16: 48. Published online 2024 Mar 26. doi: 10.1186/s13148-024-01658-2

PMCID:: PMC10964616

Abstract Article PDF–2.4M

Select item 108348623.

The miR-183/96/182 Cluster Is a Checkpoint for Resident Immune Cells and Shapes the Cellular Landscape of the Cornea

Weifeng Li, Katherine Gurdziel, Ahalya Pitchaikannu, Naman Gupta, Linda D. Hazlett, Shunbin Xu

Ocul Surf. Author manuscript; available in PMC 2024 Oct 1.

Published in final edited form as: Ocul Surf. 2023 Oct; 30: 17–41. Published online 2023 Aug 2. doi: 10.1016/j.jtos.2023.07.012

PMCID:: PMC10834862

Abstract Article PDF–3.5M

Select item 100694104.

MiR-182 Inhibition Protects Against Experimental Stroke in vivo and Mitigates Astrocyte Injury and Inflammation in vitro via Modulation of Cortactin Activity

Qasim M. Alhadidi, Lijun Xu, Xiaoyun Sun, Yusuf S. Althobaiti, Atiah Almalki, Hashem O. Alsaab, Creed M. Stary

Neurochem Res. Author manuscript; available in PMC 2023 Apr 3.

Published in final edited form as: Neurochem Res. 2022 Dec; 47(12): 3682–3696. Published online 2022 Aug 11. doi: 10.1007/s11064-022-03718-6

PMCID:: PMC10069410

Abstract Article PDF–3.1M

Select item 98283195.

miR-182-5p attenuates Schistosoma japonicum-induced hepatic fibrosis by targeting tristetraprolin : miR-182-5p attenuates hepatic fibrosis

Xuejun Zhao, Zijie Xia, Ziang Wang, Mengsi Zhou, Xuebing Qiu, Cheng Wang, Tian Xu, Qian Fang, Zhenping Ming, Huifen Dong

Acta Biochim Biophys Sin (Shanghai) 2022 Oct; 54(10): 1421–1430. Published online 2022 Sep 22. doi: 10.3724/abbs.2022130

PMCID:: PMC9828319

Abstract Article PDF–1.8M

Select item 98007266.

DNA hypermethylation-induced miR-182 silence targets BCL2 and HOXA9 to facilitate the self-renewal of leukemia stem cell, accelerate acute myeloid leukemia progression, and determine the sensitivity of BCL2 inhibitor venetoclax

Sisi Ye, Fang Xiong, Xiaofei He, Yigang Yuan, Danyang Li, Daijiao Ye, Liuzhi Shi, Zihan Lin, Min Zhao, Shuya Feng, Bin Zhou, Huachun Weng, Lili Hong, Haige Ye, Shenmeng Gao

Theranostics. 2023; 13(1): 77–94. Published online 2023 Jan 1. doi: 10.7150/thno.77404

PMCID:: PMC9800726

Abstract Article PDF–8.0M

Select item 93436437.

miR-182-5p promotes hepatocyte-stellate cell crosstalk to facilitate liver regeneration

Ting Xiao, Wen Meng, Zhangliu Jin, Jing Wang, Jiangming Deng, Jie Wen, Bilian Liu, Meilian Liu, Juli Bai, Feng Liu

Commun Biol. 2022; 5: 771. Published online 2022 Aug 1. doi: 10.1038/s42003-022-03714-0

PMCID:: PMC9343643

Abstract Article PDF–3.9M

Select item 93013148.

Deletion of microRNA-183-96-182 Cluster in Lymphocytes Suppresses Anti-DsDNA Autoantibody Production and IgG Deposition in the Kidneys in C57BL/6-Fas^lpr/lpr Mice

Zhuang Wang, Bettina Heid, Ran Lu, Mohit Sachdeva, Michael R. Edwards, JingJing Ren, Thomas E. Cecere, Deena Khan, Taschua Jeboda, David G. Kirsch, Christopher M. Reilly, Rujuan Dai, S. Ansar Ahmed

Front Genet. 2022; 13: 840060. Published online 2022 Jul 7. doi: 10.3389/fgene.2022.840060

PMCID:: PMC9301314

Abstract Article PDF–3.1M

Select item 89412309.

Inhibiting miR-182-3p Alleviates Gestational Diabetes Mellitus by Improving Insulin Resistance in Skeletal Muscle

Jinghong Rao, Youfang Chen, Jingying Huang, Ruoying Wu, Zhenzhu Dong, Yuling Gao, Xuan Chen

Balkan Med J. 2022 Mar; 39(2): 121–129. Published online 2022 Mar 14. doi: 10.4274/balkanmedj.galenos.2021.2021-8-140

PMCID:: PMC8941230

Abstract Article PDF–1.4M

Select item 883319410.

miR-182 targeting reprograms tumor-associated macrophages and limits breast cancer progression

Chengxin Ma, Dasa He, Pu Tian, Yuan Wang, Yunfei He, Qiuyao Wu, Zhenchang Jia, Xue Zhang, Peiyuan Zhang, Hao Ying, Zi-Bing Jin, Guohong Hu

Proc Natl Acad Sci U S A. 2022 Feb 8; 119(6): e2114006119. Published online 2022 Feb 1. doi: 10.1073/pnas.2114006119

PMCID:: PMC8833194

Abstract Article PDF–3.4M

Select item 868430211.

Prophylactic Knockdown of the miR-183/96/182 Cluster Ameliorates Pseudomonas aeruginosa–Induced Keratitis

Sharon McClellan, Ahalya Pitchaikannu, Robert Wright, Denise Bessert, Mason Iulianelli, Linda D. Hazlett, Shunbin Xu

Invest Ophthalmol Vis Sci. 2021 Dec; 62(15): 14. Published online 2021 Dec 17. doi: 10.1167/iovs.62.15.14

PMCID:: PMC8684302

Abstract Article PDF–7.6M

Select item 861688112.

MiRNA-182-5p aggravates experimental ulcerative colitis via sponging Claudin-2

Siwen Tang, Wentao Guo, Liumin Kang, Jinghua Liang

J Mol Histol. 2021; 52(6): 1215–1224. Published online 2021 Oct 8. doi: 10.1007/s10735-021-10021-1

PMCID:: PMC8616881

Abstract Article PDF–5.2M

Select item 849230013.

The miR-182-5p/FGF21/acetylcholine axis mediates the crosstalk between adipocytes and macrophages to promote beige fat thermogenesis

Wen Meng, Ting Xiao, Xiuci Liang, Jie Wen, Xinyi Peng, Jing Wang, Yi Zou, Jiahao Liu, Christie Bialowas, Hairong Luo, Yacheng Zhang, Bilian Liu, Jingjing Zhang, Fang Hu, Meilian Liu, Lily Q. Dong, Zhiguang Zhou, Feng Liu, Juli Bai

JCI Insight. 2021 Sep 8; 6(17): e150249. Published online 2021 Sep 8. doi: 10.1172/jci.insight.150249