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Select item 112670941.

Type III adenylyl cyclase is essential for follicular development in female mice and their reproductive lifespan

Baofang Zheng, Xiaoyu Hu, Yuanhui Hu, Sheng Dong, Xin Xiao, Haoming Qi, Yongdi Wang, Weina Wang, Zhenshan Wang

iScience. 2024 Jul 19; 27(7): 110293. Published online 2024 Jun 17. doi: 10.1016/j.isci.2024.110293

PMCID:: PMC11267094

Abstract Article PDF–6.9M

Select item 111140372.

Pax6 controls centriole maturation in cortical progenitors through Odf2

Marco A. Tylkowski, Kefei Yang, Sigrid Hoyer-Fender, Anastassia Stoykova

Cell Mol Life Sci. 2015 May; 72(9): 1795–1809. Published online 2014 Oct 29. doi: 10.1007/s00018-014-1766-1

PMCID:: PMC11114037

Abstract Article PDF–8.0M

Select item 110775893.

GDF15 controls primary cilia morphology and function thereby affecting progenitor proliferation

Katja Baur, Şeydanur Şan, Gabriele Hölzl-Wenig, Claudia Mandl, Andrea Hellwig, Francesca Ciccolini

Life Sci Alliance. 2024 Jul; 7(7): e202302384. Published online 2024 May 7. doi: 10.26508/lsa.202302384

PMCID:: PMC11077589

Abstract Article PDF–3.0M

Select item 109176604.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 107693505.

Identification of new ciliary signaling pathways in the brain and insights into neurological disorders

Abdelhalim Loukil, Emma Ebright, Akiyoshi Uezu, Yudong Gao, Scott H Soderling, Sarah C. Goetz

Version 1. bioRxiv. Preprint. 2023 Dec 21. doi: 10.1101/2023.12.20.572700

PMCID:: PMC10769350

Abstract Article PDF–11M

Select item 97444436.

Olfactory receptor 2 in vascular macrophages drives atherosclerosis by NLRP3-dependent IL-1 production

Marco Orecchioni, Kouji Kobiyama, Holger Winkels, Yanal Ghosheh, Sara McArdle, Zbigniew Mikulski, William B. Kiosses, Zhichao Fan, Lai Wen, Yunmin Jung, Payel Roy, Amal J. Ali, Yukiko Miyamoto, Matthew Mangan, Jeffrey Makings, Zhihao Wang, Angela Denn, Jenifer Vallejo, Michaela Owens, Christopher P. Durant, Simon Braumann, Navid Mader, Lin Li, Hiroaki Matsunami, Lars Eckmann, Eicke Latz, Zeneng Wang, Stanley L. Hazen, Klaus Ley

Science. Author manuscript; available in PMC 2022 Dec 12.

Published in final edited form as: Science. 2022 Jan 14; 375(6577): 214–221. Published online 2022 Jan 13. doi: 10.1126/science.abg3067

PMCID:: PMC9744443

Abstract Article PDF–2.3M

Select item 95235587.

Hippocampals neurogenesis is impaired in mice with a deletion in the coiled coil domain of Talpid3—implications for Joubert syndrome

Andrew L Bashford, Vasanta Subramanian

Hum Mol Genet. 2022 Oct 1; 31(19): 3245–3265. Published online 2022 Apr 26. doi: 10.1093/hmg/ddac095

PMCID:: PMC9523558

Abstract Article PDF–4.6M

Select item 92185078.

The role of ciliopathy-associated type 3 adenylyl cyclase in infanticidal behavior in virgin adult male mice

Xiangbo Wu, Dong Yang, Yanfen Zhou, Shujuan Li, Zhenshan Wang

iScience. 2022 Jul 15; 25(7): 104534. Published online 2022 Jun 4. doi: 10.1016/j.isci.2022.104534

PMCID:: PMC9218507

Abstract Article PDF–4.1M

Select item 91970679.

Generation and characterization of Ccdc28b mutant mice links the Bardet-Biedl associated gene with mild social behavioral phenotypes

Matías Fabregat, Sofía Niño-Rivero, Sabrina Pose, Magdalena Cárdenas-Rodríguez, Mariana Bresque, Karina Hernández, Victoria Prieto-Echagüe, Geraldine Schlapp, Martina Crispo, Patricia Lagos, Natalia Lago, Carlos Escande, Florencia Irigoín, Jose L. Badano

PLoS Genet. 2022 Jun; 18(6): e1009896. Published online 2022 Jun 2. doi: 10.1371/journal.pgen.1009896

PMCID:: PMC9197067

Abstract Article PDF–4.4M

Select item 904270810.

Ankmy2 Prevents Smoothened-Independent Hyperactivation of the Hedgehog Pathway via Cilia-Regulated Adenylyl Cyclase Signaling

Bandarigoda Nipunika Somatilaka, Sun-Hee Hwang, Vivek Reddy Palicharla, Kevin Andrew White, Hemant Badgandi, John Michael Shelton, Saikat Mukhopadhyay

Dev Cell. Author manuscript; available in PMC 2022 Apr 27.

Published in final edited form as: Dev Cell. 2020 Sep 28; 54(6): 710–726.e8. Published online 2020 Jul 22. doi: 10.1016/j.devcel.2020.06.034

PMCID:: PMC9042708

Abstract Article PDF–3.9M

Select item 885583311.

Peripheral ablation of type III adenylyl cyclase induces hyperalgesia and eliminates KOR-mediated analgesia in mice

Wen-Wen Zhang, Hong Cao, Yang Li, Xian-Jun Fu, Yu-Qiu Zhang

JCI Insight. 2022 Feb 8; 7(3): e153191. Published online 2022 Feb 8. doi: 10.1172/jci.insight.153191

PMCID:: PMC8855833

Abstract Article PDF–14M

Select item 878741012.

Ciliary Type III Adenylyl Cyclase in the VMH Is Crucial for High‐Fat Diet‐Induced Obesity Mediated by Autophagy

Dong Yang, Xiangbo Wu, Weina Wang, Yanfen Zhou, Zhenshan Wang

Adv Sci (Weinh) 2022 Jan; 9(3): 2102568. Published online 2021 Nov 16. doi: 10.1002/advs.202102568

PMCID:: PMC8787410

Abstract Article PDF–7.3M

Select item 840666613.

Adenylyl cyclase 3 regulates osteocyte mechanotransduction and primary cilium

Michael P. Duffy, McKenzie E. Sup, X. Edward Guo

Biochem Biophys Res Commun. Author manuscript; available in PMC 2022 Oct 8.

Published in final edited form as: Biochem Biophys Res Commun. 2021 Oct 8; 573: 145–150. Published online 2021 Aug 12. doi: 10.1016/j.bbrc.2021.08.033

PMCID:: PMC8406666

Abstract Article PDF–892K

Select item 808720214.

Melanocortin 4 receptor signals at the neuronal primary cilium to control food intake and body weight

Yi Wang, Adelaide Bernard, Fanny Comblain, Xinyu Yue, Christophe Paillart, Sumei Zhang, Jeremy F. Reiter, Christian Vaisse

J Clin Invest. 2021 May 3; 131(9): e142064. Published online 2021 May 3. doi: 10.1172/JCI142064

PMCID:: PMC8087202

Abstract Article PDF–9.3M

Select item 789624715.

Selective ablation of type 3 adenylyl cyclase in somatostatin-positive interneurons produces anxiety- and depression-like behaviors in mice

Xiao-Yu Yang, Zhao-Liang Ma, Daniel R Storm, Hong Cao, Yu-Qiu Zhang

World J Psychiatry. 2021 Feb 19; 11(2): 35–49. Published online 2021 Feb 19. doi: 10.5498/wjp.v11.i2.35

PMCID:: PMC7896247

Abstract Article PDF–8.9M

Select item 766621616.

Primary cilia mediate early life programming of adiposity through lysosomal regulation in the developing mouse hypothalamus

Chan Hee Lee, Do Kyeong Song, Chae Beom Park, Jeewon Choi, Gil Myoung Kang, Sung Hoon Shin, Ijoo Kwon, Soyoung Park, Seongjun Kim, Ji Ye Kim, Hong Dugu, Jae Woo Park, Jong Han Choi, Se Hee Min, Jong-Woo Sohn, Min-Seon Kim

Nat Commun. 2020; 11: 5772. Published online 2020 Nov 13. doi: 10.1038/s41467-020-19638-4