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Select item 108216101.

Identification of novel F₂-isoprostane metabolites by specific UDP-glucuronosyltransferases

Ginger L. Milne, Marina S. Nogueira, Benlian Gao, Stephanie C. Sanchez, Warda Amin, Sarah Thomas, Camille Oger, Jean-Marie Galano, Harvey J. Murff, Gong Yang, Thierry Durand

Redox Biol. 2024 Apr; 70: 103020. Published online 2024 Jan 4. doi: 10.1016/j.redox.2023.103020

PMCID:: PMC10821610

Abstract Article PDF–4.1M

Select item 92685152.

UGT1A1 and UGT1A9 Are Responsible for Phase II Metabolism of Tectorigenin and Irigenin In Vitro

Ji Li, Zhangyao Xu, Jifeng Gu

Molecules. 2022 Jul; 27(13): 4104. Published online 2022 Jun 26. doi: 10.3390/molecules27134104

PMCID:: PMC9268515

Abstract Article PDF–2.5M

Select item 81650303.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 73759524.

Genetic variants in CYP2A6 and UGT1A9 genes associated with urinary nicotine metabolites in young Mexican smokers

Gissela Borrego-Soto, Yadira X. Perez-Paramo, Gang Chen, Sandra K. Santuario-Facio, Jesus Santos-Guzman, Rodolfo Posadas-Valay, Fatima M. Alvarado-Monroy, Isaias Balderas-Renteria, Ramses Medina-Gonzalez, Rocio Ortiz-Lopez, Philip Lazarus, Augusto Rojas-Martinez

Pharmacogenomics J. 2020; 20(4): 586–594. Published online 2020 Jan 21. doi: 10.1038/s41397-020-0147-4

PMCID:: PMC7375952

Abstract Article PDF–964K

Select item 67173425.

Novel analytical methods to interpret large sequencing data from small sample sizes

Florence Lichou, Sébastien Orazio, Stéphanie Dulucq, Gabriel Etienne, Michel Longy, Christophe Hubert, Alexis Groppi, Alain Monnereau, François-Xavier Mahon, Béatrice Turcq

Hum Genomics. 2019; 13: 41. Published online 2019 Aug 30. doi: 10.1186/s40246-019-0235-1

PMCID:: PMC6717342

Abstract Article PDF–1.1M

Select item 64327666.

Sorafenib is an Inhibitor of UGT1A1 but is Metabolized by UGT1A9: Implications of Genetic Variants on Pharmacokinetics and Hyperbilirubinemia

Cody J. Peer, Tristan M. Sissung, AeRang Kim, Lokesh Jain, Sukyung Woo, Erin R. Gardner, C. Tyler Kirkland, Sarah M. Troutman, Bevin C. English, Emily D. Richardson, Joel Federspiel, David Venzon, William Dahut, Elise Kohn, Shivaani Kummar, Robert Yarchoan, Giuseppe Giaccone, Brigitte Widemann, William D. Figg

Clin Cancer Res. Author manuscript; available in PMC 2019 Mar 25.

Published in final edited form as: Clin Cancer Res. 2012 Apr 1; 18(7): 2099–2107. Published online 2012 Feb 3. doi: 10.1158/1078-0432.CCR-11-2484

PMCID:: PMC6432766

Abstract Article PDF–768K

Select item 63009897.

Glucuronidation of icaritin by human liver microsomes, human intestine microsomes and expressed UDP-glucuronosyltransferase enzymes: identification of UGT1A3, 1A9 and 2B7 as the main contributing enzymes

Li Wang, Xiaodan Hong, Zhihong Yao, Yi Dai, Guoping Zhao, Zifei Qin, Baojian Wu, Frank J. Gonzalez, Xinsheng Yao

Xenobiotica. Author manuscript; available in PMC 2018 Dec 20.

Published in final edited form as: Xenobiotica. 2018 Apr; 48(4): 357–367. Published online 2017 May 15. doi: 10.1080/00498254.2017.1323139

PMCID:: PMC6300989

Abstract Article PDF–2.7M

Select item 56539158.

Relationship between UGT1A9 gene polymorphisms, efficacy, and safety of propofol in induced abortions amongst Chinese population: a population-based study

Ying-Bin Wang, Rong-Zhi Zhang, Sheng-Hui Huang, Shu-Bao Wang, Jian-Qin Xie

Biosci Rep. 2017 Oct 31; 37(5): BSR20170722. Prepublished online 2017 Sep 12. Published online 2017 Oct 24. doi: 10.1042/BSR20170722

PMCID:: PMC5653915

Abstract Article PDF–356K

Select item 55316119.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 539138510.

The effect of UGT1A9, CYP2B6 and CYP2C9 genes polymorphism on individual differences in propofol pharmacokinetics among Polish patients undergoing general anaesthesia

Adam Mikstacki, Oliwia Zakerska-Banaszak, Marzena Skrzypczak-Zielinska, Barbara Tamowicz, Michał Prendecki, Jolanta Dorszewska, Marta Molinska-Glura, Malgorzata Waszak, Ryszard Slomski

J Appl Genet. 2017; 58(2): 213–220. Published online 2016 Nov 8. doi: 10.1007/s13353-016-0373-2

PMCID:: PMC5391385

Abstract Article PDF–300K

Select item 511471711.

Inter-isoform Hetero-dimerization of Human UDP-Glucuronosyltransferases (UGTs) 1A1, 1A9, and 2B7 and Impacts on Glucuronidation Activity

Ling-Min Yuan, Zhang-Zhao Gao, Hong-Ying Sun, Sai-Nan Qian, Yong-Sheng Xiao, Lian-Li Sun, Su Zeng

Sci Rep. 2016; 6: 34450. Published online 2016 Nov 18. doi: 10.1038/srep34450

PMCID:: PMC5114717

Abstract Article PDF–2.0M

Select item 510448012.

Regioselective Glucuronidation of Diosmetin and Chrysoeriol by the Interplay of Glucuronidation and Transport in UGT1A9-Overexpressing HeLa Cells

Xuejun Zeng, Jian Shi, Min Zhao, Qingwei Chen, Liping Wang, Huangyu Jiang, Feifei Luo, Lijun Zhu, Linlin Lu, Xinchun Wang, Zhongqiu Liu

PLoS One. 2016; 11(11): e0166239. Published online 2016 Nov 10. doi: 10.1371/journal.pone.0166239

PMCID:: PMC5104480

Abstract Article PDF–5.7M

Select item 483741513.

Dimerization of human uridine diphosphate glucuronosyltransferase allozymes 1A1 and 1A9 alters their quercetin glucuronidation activities

Yan-Qing Liu, Ling-Min Yuan, Zhang-Zhao Gao, Yong-Sheng Xiao, Hong-Ying Sun, Lu-Shan Yu, Su Zeng

Sci Rep. 2016; 6: 23763. Published online 2016 Mar 30. doi: 10.1038/srep23763

PMCID:: PMC4837415

Abstract Article PDF–1.4M

Select item 469560614.

Cloning of UGT1A9 cDNA from liver tissues and its expression in CHL cells

Xin Li, Ying-Nian Yu, Ge-Jian Zhu, Yu-Li Qian

World J Gastroenterol. 2001 Dec 15; 7(6): 841–845. Published online 2001 Dec 15. doi: 10.3748/wjg.v7.i6.841

PMCID:: PMC4695606

Abstract Article PDF–133K

Select item 444408115.

Drug-Metabolizing Activity, Protein and Gene Expression of UDP-Glucuronosyltransferases Are Significantly Altered in Hepatocellular Carcinoma Patients

Linlin Lu, Juan Zhou, Jian Shi, Xiao-juan Peng, Xiao-xiao Qi, Ying Wang, Fang-yuan Li, Fu-Yuan Zhou, Liang Liu, Zhong-Qiu Liu

PLoS One. 2015; 10(5): e0127524. Published online 2015 May 26. doi: 10.1371/journal.pone.0127524

PMCID:: PMC4444081

Abstract Article PDF–3.8M

Select item 437080816.

Genome-wide analysis of hepatic lipid content in extreme obesity

Johanna K. DiStefano, Christopher Kingsley, G. Craig Wood, Xin Chu, George Argyropoulos, Christopher D. Still, Stefania Cotta Doné, Christophe Legendre, Waibhav Tembe, Glenn S. Gerhard

Acta Diabetol. Author manuscript; available in PMC 2016 Apr 1.

Published in final edited form as: Acta Diabetol. 2015 Apr; 52(2): 373–382. Published online 2014 Sep 23. doi: 10.1007/s00592-014-0654-3

PMCID:: PMC4370808

Abstract Article PDF–611K

Select item 408814417.

Lack of association between UGT1A7, UGT1A9, ARP, SPINK1 and CFTR gene polymorphisms and pancreatic cancer in Italian patients

Ada Piepoli, Annamaria Gentile, Maria Rosa Valvano, Daniela Barana, Cristina Oliani, Rosa Cotugno, Michele Quitadamo, Angelo Andriulli, Francesco Perri

World J Gastroenterol. 2006 Oct 21; 12(39): 6343–6348. Published online 2006 Oct 21. doi: 10.3748/wjg.v12.i39.6343

PMCID:: PMC4088144

Abstract Article PDF–715K

Select item 406425418.

An atlas of genetic influences on human blood metabolites

So-Youn Shin, Eric B. Fauman, Ann-Kristin Petersen, Jan Krumsiek, Rita Santos, Jie Huang, Matthias Arnold, Idil Erte, Vincenzo Forgetta, Tsun-Po Yang, Klaudia Walter, Cristina Menni, Lu Chen, Louella Vasquez, Ana M. Valdes, Craig L. Hyde, Vicky Wang, Daniel Ziemek, Phoebe Roberts, Li Xi, Elin Grundberg, The Multiple Tissue Human Expression Resource (MuTHER) Consortium, Melanie Waldenberger, J. Brent Richards, Robert P. Mohney, Michael V. Milburn, Sally L. John, Jeff Trimmer, Fabian J. Theis, John P. Overington, Karsten Suhre, M. Julia Brosnan, Christian Gieger, Gabi Kastenmüller, Tim D Spector, Nicole Soranzo

Nat Genet. Author manuscript; available in PMC 2014 Dec 1.

Published in final edited form as: Nat Genet. 2014 Jun; 46(6): 543–550. Published online 2014 May 11. doi: 10.1038/ng.2982

PMCID:: PMC4064254

Abstract Article PDF–2.4M

Select item 403142419.

Differences in UGT1A1, UGT1A7, and UGT1A9 Polymorphisms between Uzbek and Japanese Populations

Hiromichi Maeda, Shoichi Hazama, Abdiev Shavkat, Ken Okamoto, Koji Oba, Junichi Sakamoto, Kenichi Takahashi, Masaki Oka, Daisuke Nakamura, Ryouichi Tsunedomi, Naoko Okayama, Hideyuki Mishima, Michiya Kobayashi

Mol Diagn Ther. 2014; 18(3): 333–342. Published online 2014 Jan 23. doi: 10.1007/s40291-014-0083-6

PMCID:: PMC4031424

Abstract Article PDF–880K

Select item 403072520.

Revolving Door Action of BCRP Facilitates or Controls the Efflux of Flavone Glucuronides from UGT1A9-Overexpressing HeLa Cells

Yingjie Wei, Baojian Wu, Wen Jiang, Taijun Yin, Xiaobin Jia, Sumit Basu, Guangyi Yang, Ming Hu

Mol Pharm. Author manuscript; available in PMC 2014 May 22.

Published in final edited form as: Mol Pharm. 2013 May 6; 10(5): 1736–1750. Published online 2013 Apr 23. doi: 10.1021/mp300562q

PMCID:: PMC4030725

Abstract Article PDF–3.6M

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