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Items: 1 to 20 of 43

1.
A coordinated multiorgan metabolic response contributes to human mitochondrial myopathy
Nneka Southwell, Guido Primiano, Viraj Nadkarni, Nabeel Attarwala, Emelie Beattie, Dawson Miller, Sumaitaah Alam, Irene Liparulo, Yevgeniya I Shurubor, Maria Lucia Valentino, Valerio Carelli, Serenella Servidei, Steven S Gross, Giovanni Manfredi, Qiuying Chen, Marilena D'Aurelio
EMBO Mol Med. 2023 Jul; 15(7): e16951. Published online 2023 May 24. doi: 10.15252/emmm.202216951
PMCID:
PMC10331581
AbstractArticlePDF–4.5M
2.
Mitochondrial dysfunction reactivates α-fetoprotein expression that drives copper-dependent immunosuppression in mitochondrial disease models
Kimberly A. Jett, Zakery N. Baker, Amzad Hossain, Aren Boulet, Paul A. Cobine, Sagnika Ghosh, Philip Ng, Orhan Yilmaz, Kris Barreto, John DeCoteau, Karen Mochoruk, George N. Ioannou, Christopher Savard, Sai Yuan, Osama H.M.H. Abdalla, Christopher Lowden, Byung-Eun Kim, Hai-Ying Mary Cheng, Brendan J. Battersby, Vishal M. Gohil, Scot C. Leary
J Clin Invest. 2023 Jan 3; 133(1): e154684. Published online 2023 Jan 3. doi: 10.1172/JCI154684
PMCID:
PMC9797342
AbstractArticlePDF–3.1M
3.
Mitochondrial dysfunction induces ALK5-SMAD2-mediated hypovascularization and arteriovenous malformations in mouse retinas
Haifeng Zhang, Busu Li, Qunhua Huang, Francesc López-Giráldez, Yoshiaki Tanaka, Qun Lin, Sameet Mehta, Guilin Wang, Morven Graham, Xinran Liu, In-Hyun Park, Anne Eichmann, Wang Min, Jenny Huanjiao Zhou
Nat Commun. 2022; 13: 7637. Published online 2022 Dec 10. doi: 10.1038/s41467-022-35262-w
PMCID:
PMC9741628
AbstractArticlePDF–16M
4.
Destabilizing COXIV in Müller Glia Increases Retinal Glycolysis and Alters Scotopic Electroretinogram
Nana Yaa Nsiah, Denise M. Inman
Cells. 2022 Dec; 11(23): 3756. Published online 2022 Nov 24. doi: 10.3390/cells11233756
PMCID:
PMC9737073
AbstractArticlePDF–7.3M
5.
mTORC1 signaling facilitates differential stem cell differentiation to shape the developing murine lung and is associated with mitochondrial capacity
Kuan Zhang, Erica Yao, Ethan Chuang, Biao Chen, Evelyn Y. Chuang, Pao-Tien Chuang
Nat Commun. 2022; 13: 7252. Published online 2022 Nov 25. doi: 10.1038/s41467-022-34763-y
PMCID:
PMC9700781
AbstractArticlePDF–11M
6.
Differential requirements for mitochondrial electron transport chain components in the adult murine liver
Nicholas P Lesner, Xun Wang, Zhenkang Chen, Anderson Frank, Cameron J Menezes, Sara House, Spencer D Shelton, Andrew Lemoff, David G McFadden, Janaka Wansapura, Ralph J DeBerardinis, Prashant Mishra
eLife. 2022; 11: e80919. Published online 2022 Sep 26. doi: 10.7554/eLife.80919
PMCID:
PMC9648974
AbstractArticlePDF–16M
7.
Neonatal ketone body elevation regulates postnatal heart development by promoting cardiomyocyte mitochondrial maturation and metabolic reprogramming
Danyang Chong, Yayun Gu, Tongyu Zhang, Yu Xu, Dandan Bu, Zhong Chen, Na Xu, Liangkui Li, Xiyu Zhu, Haiquan Wang, Yangqing Li, Feng Zheng, Dongjin Wang, Peng Li, Li Xu, Zhibin Hu, Chaojun Li
Cell Discov. 2022; 8: 106. Published online 2022 Oct 11. doi: 10.1038/s41421-022-00447-6
PMCID:
PMC9553951
AbstractArticlePDF–3.8M
8.
Enhanced glycolysis and GSK3 inactivation promote brain metabolic adaptations following neuronal mitochondrial stress
Sofia Garcia, Amy Saldana-Caboverde, Mir Anwar, Ami Pravinkant Raval, Nadee Nissanka, Milena Pinto, Carlos Torres Moraes, Francisca Diaz
Hum Mol Genet. 2022 Mar 1; 31(5): 692–704. Published online 2021 Sep 24. doi: 10.1093/hmg/ddab282
PMCID:
PMC9077416
AbstractArticlePDF–1.3M
9.
Scinderin promotes fusion of electron transport chain dysfunctional muscle stem cells with myofibers
Xun Wang, Spencer D. Shelton, Bogdan Bordieanu, Anderson R. Frank, Yating Yi, Siva Sai Krishna Venigalla, Zhimin Gu, Nicholas P. Lenser, Michael Glogauer, Navdeep S. Chandel, Hu Zhao, Zhiyu Zhao, David G. McFadden, Prashant Mishra
Nat Aging. Author manuscript; available in PMC 2022 Mar 25.
Published in final edited form as: Nat Aging. 2022; 2(2): 155–169. Published online 2022 Jan 27. doi: 10.1038/s43587-021-00164-x
PMCID:
PMC8954567
AbstractArticlePDF–7.7M
10.
Reliance on Cox10 and oxidative metabolism for antigen-specific NK cell expansion
Annelise Y. Mah-Som, Molly P. Keppel, Joshua M. Tobin, Ana Kolicheski, Nermina Saucier, Veronika Sexl, Anthony R. French, Julia A. Wagner, Todd A. Fehniger, Megan A. Cooper
Cell Rep. Author manuscript; available in PMC 2021 Jun 25.
Published in final edited form as: Cell Rep. 2021 Jun 1; 35(9): 109209. doi: 10.1016/j.celrep.2021.109209
PMCID:
PMC8229496
AbstractArticlePDF–1.8M
11.
Mitochondrial respiration controls neoangiogenesis during wound healing and tumour growth
L. M. Schiffmann, J. P. Werthenbach, F. Heintges-Kleinhofer, J. M. Seeger, M. Fritsch, S. D. Günther, S. Willenborg, S. Brodesser, C. Lucas, C. Jüngst, M. C. Albert, F. Schorn, A. Witt, C. T. Moraes, C. J. Bruns, M. Pasparakis, M. Krönke, S. A. Eming, O. Coutelle, H. Kashkar
Nat Commun. 2020; 11: 3653. Published online 2020 Jul 21. doi: 10.1038/s41467-020-17472-2
PMCID:
PMC7374592
AbstractArticlePDF–3.2M
12.
Mitochondrial disease disrupts hepatic allostasis and lowers the threshold for immune-mediated liver toxicity
Maxim Jestin, Senta M. Kapnick, Tatyana N. Tarasenko, Cassidy T. Burke, Patricia M. Zerfas, Francisca Diaz, Hilary Vernon, Larry N. Singh, Ronald J. Sokol, Peter J. McGuire
Mol Metab. 2020 Jul; 37: 100981. Published online 2020 Mar 26. doi: 10.1016/j.molmet.2020.100981
PMCID:
PMC7167504
AbstractArticlePDF–3.0M
13.
Impaired mitophagy links mitochondrial disease to epithelial stress in methylmalonyl-CoA mutase deficiency
Alessandro Luciani, Anke Schumann, Marine Berquez, Zhiyong Chen, Daniela Nieri, Mario Failli, Huguette Debaix, Beatrice Paola Festa, Natsuko Tokonami, Andrea Raimondi, Alessio Cremonesi, Diego Carrella, Patrick Forny, Stefan Kölker, Francesca Diomedi Camassei, Francisca Diaz, Carlos T. Moraes, Diego Di Bernardo, Matthias R. Baumgartner, Olivier Devuyst
Nat Commun. 2020; 11: 970. Published online 2020 Feb 20. doi: 10.1038/s41467-020-14729-8
Correction in:
Nat Commun. 2020; 11: 1719.
PMCID:
PMC7033137
AbstractArticlePDF–4.9M
14.
Hyperoxia but not AOX expression mitigates pathological cardiac remodeling in a mouse model of inflammatory cardiomyopathy
Praveen K. Dhandapani, Isabel M. Begines-Moreno, Gloria Brea-Calvo, Ulrich Gärtner, Thomas G. Graeber, Gerardo Javier Sanchez, Rory E. Morty, Kai Schönig, Johanna ten Hoeve, Astrid Wietelmann, Thomas Braun, Howard T. Jacobs, Marten Szibor
Sci Rep. 2019; 9: 12741. Published online 2019 Sep 4. doi: 10.1038/s41598-019-49231-9
PMCID:
PMC6726756
AbstractArticlePDF–2.3M
15.
Respiration-Deficient Astrocytes Survive As Glycolytic Cells In Vivo
Lotti M. Supplie, Tim Düking, Graham Campbell, Francisca Diaz, Carlos T. Moraes, Magdalena Götz, Bernd Hamprecht, Susann Boretius, Don Mahad, Klaus-Armin Nave
J Neurosci. 2017 Apr 19; 37(16): 4231–4242. doi: 10.1523/JNEUROSCI.0756-16.2017
PMCID:
PMC6596567
AbstractArticlePDF–6.1M
16.
Regulation of gene expression by miR-144/451 during mouse erythropoiesis
Peng Xu, Lance E. Palmer, Christophe Lechauve, Guowei Zhao, Yu Yao, Jing Luan, Anastasios Vourekas, Haiyan Tan, Junmin Peng, John D. Schuetz, Zissimos Mourelatos, Gang Wu, Mitchell J. Weiss, Vikram R. Paralkar
Blood. 2019 Jun 6; 133(23): 2518–2528. Prepublished online 2019 Apr 10. doi: 10.1182/blood.2018854604
PMCID:
PMC6557621
AbstractArticle
17.
Deletion of the Mitochondrial Complex-IV Cofactor Heme A:Farnesyltransferase Causes Focal Segmental Glomerulosclerosis and Interferon Response
Jea-Hyun Baek, Ivan G. Gomez, Yukihiro Wada, Allie Roach, Don Mahad, Jeremy S. Duffield
Am J Pathol. 2018 Dec; 188(12): 2745–2762. doi: 10.1016/j.ajpath.2018.08.018
PMCID:
PMC6334261
AbstractArticle
18.
Rewiring of glutamine metabolism is a bioenergetic adaptation of human cells with mitochondrial DNA mutations
Qiuying Chen, Kathryne Kirk, Yevgeniya I. Shurubor, Dazhi Zhao, Andrea J. Arreguin, Ifrah Shahi, Federica Valsecchi, Guido Primiano, Elizabeth L. Calder, Valerio Carelli, Travis T. Denton, Flint M. Beal, Steven S. Gross, Giovanni Manfredi, Marilena D’Aurelio
Cell Metab. Author manuscript; available in PMC 2019 May 1.
Published in final edited form as: Cell Metab. 2018 May 1; 27(5): 1007–1025.e5. Published online 2018 Apr 12. doi: 10.1016/j.cmet.2018.03.002
PMCID:
PMC5932217
AbstractArticlePDF–1.3M
19.
Cytochrome c Oxidase Activity Is a Metabolic Checkpoint that Regulates Cell Fate Decisions During T Cell Activation and Differentiation
Tatyana N. Tarasenko, Susan E. Pacheco, Mary Kay Koenig, Julio Gomez-Rodriguez, Senta M. Kapnick, Francisca Diaz, Patricia M. Zerfas, Emanuele Barca, Jessica Sudderth, Ralph J. DeBerardinis, Raul Covian, Robert S. Balaban, Salvatore DiMauro, Peter J. McGuire
Cell Metab. Author manuscript; available in PMC 2018 Jun 6.
Published in final edited form as: Cell Metab. 2017 Jun 6; 25(6): 1254–1268.e7. doi: 10.1016/j.cmet.2017.05.007
PMCID:
PMC5562283
AbstractArticlePDF–2.4M
20.
Integrative proteomics and phosphoproteomics profiling reveals dynamic signaling networks and bioenergetics pathways underlying T cell activation
Haiyan Tan, Kai Yang, Yuxin Li, Timothy I. Shaw, Yanyan Wang, Daniel Bastardo Blanco, Xusheng Wang, Ji-Hoon Cho, Hong Wang, Sherri Rankin, Cliff Guy, Junmin Peng, Hongbo Chi
Immunity. Author manuscript; available in PMC 2018 Mar 21.
Published in final edited form as: Immunity. 2017 Mar 21; 46(3): 488–503. Published online 2017 Mar 9. doi: 10.1016/j.immuni.2017.02.010
PMCID:
PMC5466820
AbstractArticlePDF–3.6M

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