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Items: 1 to 20 of 105

1.
The Alzheimer’s disease–linked protease BACE2 cleaves VEGFR3 and modulates its signaling
Andree Schmidt, Brian Hrupka, Frauke van Bebber, Sanjay Sunil Kumar, Xiao Feng, Sarah K. Tschirner, Marlene Aßfalg, Stephan A. Müller, Laura Sophie Hilger, Laura I. Hofmann, Martina Pigoni, Georg Jocher, Iryna Voytyuk, Emily L. Self, Mana Ito, Kana Hyakkoku, Akimasa Yoshimura, Naotaka Horiguchi, Regina Feederle, Bart De Strooper, Stefan Schulte-Merker, Eckhard Lammert, Dieder Moechars, Bettina Schmid, Stefan F. Lichtenthaler
J Clin Invest. 2024 Aug 15; 134(16): e170550. Published online 2024 Jun 18. doi: 10.1172/JCI170550
PMCID:
PMC11324312
AbstractArticlePDF–8.1M
2.
FLT4 gene polymorphisms influence isolated ventricular septal defect predisposition in a Southwest China population
Yunhan Zhang, Xiaoli Dong, Jun Zhang, Miao Zhao, Jiang Wang, Jiayou Chu, Zhaoqing Yang, Shaohui Ma, Keqin Lin, Hao Sun, Zhiling Luo
BMC Med Genomics. 2024; 17: 197. Published online 2024 Aug 6. doi: 10.1186/s12920-024-01971-y
PMCID:
PMC11302092
AbstractArticlePDF–1.9M
3.
Impact of vascular endothelial growth factor receptor 1, 2, and 3 expression on the outcome of patients with gastric cancer
Yoshinori Hirashima, Yasuhide Yamada, Junichi Matsubara, Daisuke Takahari, Natsuko Okita, Atsuo Takashima, Ken Kato, Tetsuya Hamaguchi, Kuniaki Shirao, Yasuhiro Shimada, Hirokazu Taniguchi, Tadakazu Shimoda
Cancer Sci. 2009 Feb; 100(2): 310–315. Published online 2008 Dec 7. doi: 10.1111/j.1349-7006.2008.01020.x
PMCID:
PMC11159319
AbstractArticlePDF–301K
4.
Association study of FLT4 and HYDIN single nucleotide polymorphisms with atrial septal defect susceptibility in the Han Chinese population of Southwest China
Ye Jin, Miao Zhao, Qiuzhe Guo, Wanyu Zhao, Min Lei, Yifei Zhang, Yunhan zhang, Yan Shen, Keqin Lin, Zhaoqing Yang, Jiayou Chu, Hao Sun, Zhiling Luo
Ital J Pediatr. 2024; 50: 62. Published online 2024 Apr 5. doi: 10.1186/s13052-024-01630-z
PMCID:
PMC10998412
AbstractArticlePDF–1.2M
5.
The pathological roles and potential mechanisms of vascular endothelial growth factor receptor-3 in gastric cancer
Xiu-Feng Li, Xiu-Juan Zhang, Fu-Rong Hao, Xiao-Tong Dong, Guo-Dong Xu, Yun-Xiang Zhang
J Int Med Res. 2024 Mar; 52(3): 03000605241234558. Published online 2024 Mar 22. doi: 10.1177/03000605241234558
PMCID:
PMC10960338
AbstractArticlePDF–1.7M
6.
FLT4 as a marker for predicting prognostic risk of refractory acute myeloid leukemia
Ji Yoon Lee, Sung-Eun Lee, A-Reum Han, Jongeun Lee, Young-sup Yoon, Hee-Je Kim
Haematologica. 2023 Nov 1; 108(11): 2933–2945. Published online 2023 Jun 15. doi: 10.3324/haematol.2022.282472
PMCID:
PMC10620598
AbstractArticlePDF–2.2M
7.
VEGFR3 is required for button junction formation in lymphatic vessels
Melanie Jannaway, Drishya Iyer, Diandra M. Mastrogiacomo, Kunyu Li, Derek C. Sung, Ying Yang, Mark L. Kahn, Joshua P. Scallan
Cell Rep. Author manuscript; available in PMC 2023 Sep 15.
Published in final edited form as: Cell Rep. 2023 Jul 25; 42(7): 112777. Published online 2023 Jul 16. doi: 10.1016/j.celrep.2023.112777
PMCID:
PMC10503778
AbstractArticlePDF–1.5M
8.
High VEGFR3 Expression Reduces Doxorubicin Efficacy in Triple-Negative Breast Cancer
Sandra Torres-Ruiz, Eduardo Tormo, Iris Garrido-Cano, Ana Lameirinhas, Federico Rojo, Juan Madoz-Gúrpide, Octavio Burgués, Cristina Hernando, Begoña Bermejo, María Teresa Martínez, Ana Lluch, Juan Miguel Cejalvo, Pilar Eroles
Int J Mol Sci. 2023 Feb; 24(4): 3601. Published online 2023 Feb 10. doi: 10.3390/ijms24043601
PMCID:
PMC9966352
AbstractArticlePDF–1.5M
9.
A novel stop-gain pathogenic variant in FLT4 and a nonsynonymous pathogenic variant in PTPN11 associated with congenital heart defects
Avisa Tabib, Taravat Talebi, Serwa Ghasemi, Maryam Pourirahim, Niloofar Naderi, Majid Maleki, Samira Kalayinia
Eur J Med Res. 2022; 27: 286. Published online 2022 Dec 10. doi: 10.1186/s40001-022-00920-8
PMCID:
PMC9737984
AbstractArticlePDF–2.3M
10.
PTEN regulates invasiveness in pancreatic neuroendocrine tumors through DUSP19-mediated VEGFR3 dephosphorylation
Tsung-Ming Chang, Pei-Yi Chu, Hui-You Lin, Kuo-Wei Huang, Wen-Chun Hung, Yan-Shen Shan, Li-Tzong Chen, Hui-Jen Tsai
J Biomed Sci. 2022; 29: 92. Published online 2022 Nov 6. doi: 10.1186/s12929-022-00875-2
PMCID:
PMC9639322
AbstractArticlePDF–4.5M
11.
ADSCs stimulated by VEGF-C alleviate intestinal inflammation via dual mechanisms of enhancing lymphatic drainage by a VEGF-C/VEGFR-3-dependent mechanism and inhibiting the NF-κB pathway by the secretome
Lei Zhang, Chen Ye, Peng Li, Chuanding Li, Weigang Shu, Yujie Zhao, Xiaolei Wang
Stem Cell Res Ther. 2022; 13: 448. Published online 2022 Sep 5. doi: 10.1186/s13287-022-03132-3
PMCID:
PMC9442958
AbstractArticlePDF–9.1M
12.
Vascular Endothelial Growth Factor Receptor-3 Expression Predicts Sentinel Node Status in Primary Cutaneous Melanoma
Ferdinand TOBERER, Holger A. HAENSSLE, Martin LAIMER, Monika HEINZEL-GUTENBRUNNER, Alexander ENK, Wolfgang HARTSCHUH, Peter HELMBOLD, Heinz KUTZNER
Acta Derm Venereol. 2020; 100(15): 5837. Published online 2020 Aug 17. doi: 10.2340/00015555-3588
PMCID:
PMC9207649
AbstractArticlePDF–3.2M
13.
Physical and functional interactome atlas of human receptor tyrosine kinases
Kari Salokas, Xiaonan Liu, Tiina Öhman, Iftekhar Chowdhury, Lisa Gawriyski, Salla Keskitalo, Markku Varjosalo
EMBO Rep. 2022 Jun; 23(6): e54041. Published online 2022 Apr 5. doi: 10.15252/embr.202154041
PMCID:
PMC9171411
AbstractArticlePDF–1.9M
14.
FLT4 Mutations Are Associated with Segmental Lymphatic Dysfunction and Initial Lymphatic Aplasia in Patients with Milroy Disease
Ningfei Liu, Minzhe Gao
Genes (Basel) 2021 Oct; 12(10): 1611. Published online 2021 Oct 13. doi: 10.3390/genes12101611
PMCID:
PMC8535675
AbstractArticlePDF–1.2M
15.
A family with Milroy disease caused by the FLT4/VEGFR3 gene variant c.2774 T > A
Yu Sui, Yongping Lu, Meina Lin, Xiang Ni, Xinren Chen, Huan Li, Miao Jiang
BMC Med Genomics. 2021; 14: 151. Published online 2021 Jun 8. doi: 10.1186/s12920-021-00997-w
PMCID:
PMC8186030
AbstractArticlePDF–1.2M
16.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
17.
An immunohistochemical study of lymphatic elements in the human brain
Éva Mezey, Ildikó Szalayova, Christopher T. Hogden, Alexandra Brady, Ágnes Dósa, Péter Sótonyi, Miklós Palkovits
Proc Natl Acad Sci U S A. 2021 Jan 19; 118(3): e2002574118. Published online 2021 Jan 14. doi: 10.1073/pnas.2002574118
PMCID:
PMC7826383
AbstractArticlePDF–3.8M
18.
In silico APC/C substrate discovery reveals cell cycle-dependent degradation of UHRF1 and other chromatin regulators
Jennifer L. Franks, Raquel C. Martinez-Chacin, Xianxi Wang, Rochelle L. Tiedemann, Thomas Bonacci, Rajarshi Choudhury, Derek L. Bolhuis, Taylor P. Enrico, Ryan D. Mouery, Jeffrey S. Damrauer, Feng Yan, Joseph S. Harrison, M. Ben Major, Katherine A. Hoadley, Aussie Suzuki, Scott B. Rothbart, Nicholas G. Brown, Michael J. Emanuele
PLoS Biol. 2020 Dec; 18(12): e3000975. Published online 2020 Dec 11. doi: 10.1371/journal.pbio.3000975
PMCID:
PMC7758050
AbstractArticlePDF–4.2M
19.
Suppression of lymph node and lung metastases of endometrial cancer by muscle‐mediated expression of soluble vascular endothelial growth factor receptor‐3
Kayoko Takahashi, Hiroaki Mizukami, Yasushi Saga, Yuji Takei, Masashi Urabe, Akihiro Kume, Shizuo Machida, Hiroyuki Fujiwara, Mitsuaki Suzuki, Keiya Ozawa
Cancer Sci. 2013 Aug; 104(8): 1107–1111. Published online 2013 Jun 4. doi: 10.1111/cas.12184
PMCID:
PMC7657111
AbstractArticlePDF–749K
20.
S1PR1 regulates the quiescence of lymphatic vessels by inhibiting laminar shear stress–dependent VEGF-C signaling
Xin Geng, Keisuke Yanagida, Racheal G. Akwii, Dongwon Choi, Lijuan Chen, YenChun Ho, Boksik Cha, Md. Riaj Mahamud, Karen Berman de Ruiz, Hirotake Ichise, Hong Chen, Joshua D. Wythe, Constantinos M. Mikelis, Timothy Hla, R. Sathish Srinivasan
JCI Insight. 2020 Jul 23; 5(14): e137652. Published online 2020 Jul 23. doi: 10.1172/jci.insight.137652
PMCID:
PMC7453895
AbstractArticlePDF–5.9M

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