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Select item 108427581.

LAIR-1 limits macrophage activation in acute inflammatory lung injury

Doumet Georges Helou, Christine Quach, Benjamin P. Hurrell, Xin Li, Meng Li, Amitis Akbari, Stephen Shen, Pedram Shafiei-Jahani, Omid Akbari

Mucosal Immunol. Author manuscript; available in PMC 2024 Feb 5.

Published in final edited form as: Mucosal Immunol. 2023 Dec; 16(6): 788–800. Published online 2023 Sep 10. doi: 10.1016/j.mucimm.2023.08.003

PMCID:: PMC10842758

Abstract Article PDF–2.4M

Select item 105793002.

LAIR1 drives glioma progression by nuclear focal adhesion kinase dependent expressions of cyclin D1 and immunosuppressive chemokines/cytokines

Xiaoqian Wei, Shushan Pan, Zirui Wang, Jieru Chen, Li Lu, Qizhi Cao, Shuling Song, Huachang Zhang, Xiaohui Liu, Xianjun Qu, Xiukun Lin, Huanli Xu

Cell Death Dis. 2023 Oct; 14(10): 684. Published online 2023 Oct 16. doi: 10.1038/s41419-023-06199-9

PMCID:: PMC10579300

Abstract Article PDF–7.0M

Select item 98446213.

Development and validation of a leukocyte‐associated immunoglobulin‐like receptor‐1 prognostic signature for lower‐grade gliomas

Zhansheng Fang, Li Lin, Zewei Tu, Xingen Zhu, Jingying Li, Pengxiang Luo, Kai Huang, Lei Wu

Cancer Med. 2023 Jan; 12(1): 712–732. Published online 2022 Jun 15. doi: 10.1002/cam4.4945

PMCID:: PMC9844621

Abstract Article PDF–11M

Select item 96041244.

Cytotoxic T Cell Expression of Leukocyte-Associated Immunoglobulin-Like Receptor-1 (LAIR-1) in Viral Hepatitis C-Mediated Hepatocellular Carcinoma

Reham Hammad, Reda Badr Aglan, Shaymaa A. Mohammed, Eman Abu-elnasr Awad, Marwa A. Elsaid, Hanan M. Bedair, Seham K. Khirala, Mohamed A Selim, Asmaa A. Abo Elqasem, Areej Rushdi, Mohamed Ali, Omaima I. Abo-Elkheir, Eman F. Sanad, Nadia M. Hamdy

Int J Mol Sci. 2022 Oct; 23(20): 12541. Published online 2022 Oct 19. doi: 10.3390/ijms232012541

PMCID:: PMC9604124

Abstract Article PDF–2.0M

Select item 82709055.

Structural basis of LAIR1 targeting by polymorphic Plasmodium RIFINs

Kai Xu, Yiran Wang, Chen-Hsiang Shen, Yiwei Chen, Baoshan Zhang, Kevin Liu, Yaroslav Tsybovsky, Shuishu Wang, S. Katie Farney, Jason Gorman, Tyler Stephens, Raffaello Verardi, Yongping Yang, Tongqing Zhou, Gwo-Yu Chuang, Antonio Lanzavecchia, Luca Piccoli, Peter D. Kwong

Nat Commun. 2021; 12: 4226. Published online 2021 Jul 9. doi: 10.1038/s41467-021-24291-6

PMCID:: PMC8270905

Abstract Article PDF–3.2M

Select item 81650306.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 77875517.

Immunoregulatory complement receptor-1 and leukocyte-associated Ig-like receptor-1 expression on leukocytes in Psoriasis vulgaris

Reham Hammad, Mervat Hamdino, Asmaa M El-Nasser, Ali Sobhy, Noha Abdel-Rahman Eldesoky, Alya Mohammad Mashaal, Hany F Ali

Innate Immun. 2020 Nov; 26(8): 683–692. Published online 2020 Jul 30. doi: 10.1177/1753425920942570

PMCID:: PMC7787551

Abstract Article PDF–661K

Select item 74857208.

LAIR-1 suppresses cell growth of ovarian cancer cell via the PI3K-AKT-mTOR pathway

Yan Liu, Li Ma, Fugen Shangguan, Xuena Zhao, Wenjie Wang, Zhiyue Gao, Huimin Zhou, Guiwu Qu, Yumei Huang, Jing An, Jiangnan Xue, Shude Yang, Qizhi Cao

Aging (Albany NY) 2020 Aug 31; 12(16): 16142–16154. Published online 2020 Aug 31. doi: 10.18632/aging.103589

PMCID:: PMC7485720

Abstract Article PDF–1.3M

Select item 74812129.

Collagen promotes anti-PD-1/PD-L1 resistance in cancer through LAIR1-dependent CD8⁺ T cell exhaustion

David H. Peng, Bertha Leticia Rodriguez, Lixia Diao, Limo Chen, Jing Wang, Lauren A. Byers, Ying Wei, Harold A. Chapman, Mitsuo Yamauchi, Carmen Behrens, Gabriela Raso, Luisa Maren Solis Soto, Edwin Roger Parra Cuentes, Ignacio I. Wistuba, Jonathan M. Kurie, Don L. Gibbons

Nat Commun. 2020; 11: 4520. Published online 2020 Sep 9. doi: 10.1038/s41467-020-18298-8

PMCID:: PMC7481212

Abstract Article PDF–5.7M

Select item 746654010.

Leukocyte Associated Immunoglobulin Like Receptor 1 Regulation and Function on Monocytes and Dendritic Cells During Inflammation

Tiago Carvalheiro, Samuel Garcia, M. Inês Pascoal Ramos, Barbara Giovannone, Timothy R. D. J. Radstake, Wioleta Marut, Linde Meyaard

Front Immunol. 2020; 11: 1793. Published online 2020 Aug 19. doi: 10.3389/fimmu.2020.01793

PMCID:: PMC7466540

Abstract Article PDF–2.3M

Select item 734551011.

LAIR-1 overexpression inhibits epithelial–mesenchymal transition in osteosarcoma via GLUT1-related energy metabolism

Jinxue Zhang, Yuan Zhang, Shiyang Cheng, Yang Mu, Yongming Liu, Xin Yi, Dongxu Jiang, Yong Ding, Ran Zhuang

World J Surg Oncol. 2020; 18: 136. Published online 2020 Jun 20. doi: 10.1186/s12957-020-01896-7

PMCID:: PMC7345510

Abstract Article PDF–3.3M

Select item 703956912.

Leukocyte-associated immunoglobulin-like receptor 1 inhibits T-cell signaling by decreasing protein phosphorylation in the T-cell signaling pathway

Jeoung-Eun Park, David D. Brand, Edward F. Rosloniec, Ae-Kyung Yi, John M. Stuart, Andrew H. Kang, Linda K. Myers

J Biol Chem. 2020 Feb 21; 295(8): 2239–2247. Published online 2020 Jan 13. doi: 10.1074/jbc.RA119.011150

PMCID:: PMC7039569

Abstract Article PDF–2.0M

Select item 670205213.

Clustered mutations at the murine and human IgH locus exhibit significant linkage consistent with templated mutagenesis

Gordon A. Dale, Daniel J. Wilkins, Caitlin D. Bohannon, Dario Dilernia, Eric Hunter, Trevor Bedford, Rustom Antia, Ignacio Sanz, Joshy Jacob

J Immunol. Author manuscript; available in PMC 2020 Sep 1.

Published in final edited form as: J Immunol. 2019 Sep 1; 203(5): 1252–1264. Published online 2019 Aug 2. doi: 10.4049/jimmunol.1801615

PMCID:: PMC6702052

Abstract Article PDF–2.1M

Select item 664241114.

Molecular basis of reduced LAIR1 expression in childhood severe malarial anaemia: Implications for leukocyte inhibitory signalling

Angela O. Achieng, Bernard Guyah, Qiuying Cheng, John M. Ong'echa, Collins Ouma, Christophe G. Lambert, Douglas J. Perkins

EBioMedicine. 2019 Jul; 45: 278–289. Published online 2019 Jun 27. doi: 10.1016/j.ebiom.2019.06.040

PMCID:: PMC6642411

Abstract Article PDF–1.8M

Select item 664228715.

Integrated OMICS platforms identify LAIR1 genetic variants as novel predictors of cross-sectional and longitudinal susceptibility to severe malaria and all-cause mortality in Kenyan children

Angela O. Achieng, Nicolas W. Hengartner, Evans Raballah, Qiuying Cheng, Samuel B. Anyona, Nick Lauve, Bernard Guyah, Ivy Foo-Hurwitz, John M. Ong'echa, Benjamin H. McMahon, Collins Ouma, Christophe G. Lambert, Douglas J. Perkins

EBioMedicine. 2019 Jul; 45: 290–302. Published online 2019 Jul 2. doi: 10.1016/j.ebiom.2019.06.043

PMCID:: PMC6642287

Abstract Article PDF–1.6M

Select item 645182116.

Expression of LAIR-1 (CD305) on Human Blood Monocytes as a Marker of Hepatic Cirrhosis Progression

María Martínez-Esparza, Antonio José Ruiz-Alcaraz, Violeta Carmona-Martínez, María Dolores Fernández-Fernández, Gonzalo Antón, María Muñoz-Tornero, Miriam Lencina, Inmaculada Pagán, Jesús de la Peña, Pilar García-Peñarrubia

J Immunol Res. 2019; 2019: 2974753. Published online 2019 Mar 24. doi: 10.1155/2019/2974753

PMCID:: PMC6451821

Abstract Article PDF–5.7M

Select item 631842217.

Low Expression of Leucocyte Associated Immunoglobulin Like Receptor-1 (LAIR-1/CD305) in a Cohort of Pediatric Acute Lymphoblastic Leukemia Cases

Minu Singh, Prateek Bhatia, Jitendra K Shandilya, Amit Rawat, Neelam Varma, Manupdesh Singh Sachdeva, Amita Trehan, Deepak Bansal, Richa Jain, Sidharth Totadri

Asian Pac J Cancer Prev. 2018; 19(11): 3131–3135. doi: 10.31557/APJCP.2018.19.11.3131

PMCID:: PMC6318422

Abstract Article PDF–359K

Select item 590470518.

LAIR‐1 shedding from human fibroblast‐like synoviocytes in rheumatoid arthritis following TNF‐α stimulation

Y. Zhang, S. Wang, H. Dong, X. Yi, J. Zhang, X. Liu, R. Zhuang, Y. Ding

Clin Exp Immunol. 2018 May; 192(2): 193–205. Published online 2018 Feb 20. doi: 10.1111/cei.13100

PMCID:: PMC5904705

Abstract Article PDF–1.0M

Select item 574889319.

Immune evasion of Plasmodium falciparum by RIFIN via inhibitory receptors

Fumiji Saito, Kouyuki Hirayasu, Takeshi Satoh, Christian W. Wang, John Lusingu, Takao Arimori, Kyoko Shida, Nirianne Marie Q. Palacpac, Sawako Itagaki, Shiroh Iwanaga, Eizo Takashima, Takafumi Tsuboi, Masako Kohyama, Tadahiro Suenaga, Marco Colonna, Junichi Takagi, Thomas Lavstsen, Toshihiro Horii, Hisashi Arase

Nature. Author manuscript; available in PMC 2018 May 29.

Published in final edited form as: Nature. 2017 Dec 7; 552(7683): 101–105. Published online 2017 Nov 29. doi: 10.1038/nature24994

Correction in:: Nature. 2018 Feb 14

PMCID:: PMC5748893

Abstract Article PDF–5.2M

Select item 574006620.

Leukocyte-Associated Immunoglobulin-like Receptor-1 is regulated in human myocardial infarction but its absence does not affect infarct size in mice

Guilielmus H. J. M. Ellenbroek, Judith J. de Haan, Bas R. van Klarenbosch, Maike A. D. Brans, Sander M. van de Weg, Mirjam B. Smeets, Sanne de Jong, Fatih Arslan, Leo Timmers, Marie-José T. H. Goumans, Imo E. Hoefer, Pieter A. Doevendans, Gerard Pasterkamp, Linde Meyaard, Saskia C. A. de Jager

Sci Rep. 2017; 7: 18039. Published online 2017 Dec 21. doi: 10.1038/s41598-017-13678-5

PMCID:: PMC5740066

Abstract Article PDF–4.9M

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