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Items: 1 to 20 of 150

1.
Crosstalk between BER and NHEJ in XRCC4-Deficient Cells Depending on hTERT Overexpression
Svetlana V. Sergeeva, Polina S. Loshchenova, Dmitry Yu. Oshchepkov, Konstantin E. Orishchenko
Int J Mol Sci. 2024 Oct; 25(19): 10405. Published online 2024 Sep 27. doi: 10.3390/ijms251910405
PMCID:
PMC11476898
AbstractArticlePDF–4.5M
2.
Antagonistic roles of canonical and alternative-RPA in disease-associated tandem CAG repeat instability
Terence Gall-Duncan, Jennifer Luo, Carla-Marie Jurkovic, Laura A. Fischer, Kyota Fujita, Amit L. Deshmukh, Rachel J. Harding, Stephanie Tran, Mustafa Mehkary, Vanessa Li, David E. Leib, Ran Chen, Hikari Tanaka, Amanda G. Mason, Dominique Lévesque, Mahreen Khan, Mortezaali Razzaghi, Tanya Prasolava, Stella Lanni, Nozomu Sato, Marie-Christine Caron, Gagan B. Panigrahi, Peixiang Wang, Rachel Lau, Arturo López Castel, Jean-Yves Masson, Lynette Tippett, Clinton Turner, Maria Spies, Albert R. La Spada, Eric I. Campos, Maurice A. Curtis, François-Michel Boisvert, Richard L.M. Faull, Beverly L. Davidson, Masayuki Nakamori, Hitoshi Okazawa, Marc S. Wold, Christopher E. Pearson
Cell. Author manuscript; available in PMC 2024 Oct 26.
Published in final edited form as: Cell. 2023 Oct 26; 186(22): 4898–4919.e25. Published online 2023 Oct 11. doi: 10.1016/j.cell.2023.09.008
PMCID:
PMC11209935
AbstractArticlePDF–3.0M
3.
BRCA1 and XRCC1 polymorphisms associated with survival in advanced gastric cancer treated with taxane and cisplatin
Hyun Jeong Shim, Joo Young Yun, Jun Eul Hwang, Woo Kyun Bae, Sang Hee Cho, Ji Hee Lee, Hee Nam Kim, Min Ho Shin, Sun Seog Kweon, Jae Hyuk Lee, Hyeoung Joon Kim, Ik Joo Chung
Cancer Sci. 2010 May; 101(5): 1247–1254. Published online 2010 Mar 12. doi: 10.1111/j.1349-7006.2010.01514.x
PMCID:
PMC11158840
AbstractArticlePDF–215K
4.
Systematic discovery of protein interaction interfaces using AlphaFold and experimental validation
Chop Yan Lee, Dalmira Hubrich, Julia K Varga, Christian Schäfer, Mareen Welzel, Eric Schumbera, Milena Djokic, Joelle M Strom, Jonas Schönfeld, Johanna L Geist, Feyza Polat, Toby J Gibson, Claudia Isabelle Keller Valsecchi, Manjeet Kumar, Ora Schueler-Furman, Katja Luck
Mol Syst Biol. 2024 Feb; 20(2): 75–97. Published online 2024 Jan 15. doi: 10.1038/s44320-023-00005-6
PMCID:
PMC10883280
AbstractArticlePDF–3.4M
5.
Androgen signaling stabilizes genomes to counteract senescence by promoting XRCC4 transcription
Yu Chen, Zhengyi Zhen, Lingjiang Chen, Hao Wang, Xuhui Wang, Xiaoxiang Sun, Zhiwei Song, Haiyan Wang, Yizi Lin, Wenjun Zhang, Guizhu Wu, Ying Jiang, Zhiyong Mao
EMBO Rep. 2023 Dec; 24(12): e56984. Published online 2023 Nov 13. doi: 10.15252/embr.202356984
PMCID:
PMC10702805
AbstractArticlePDF–1.2M
6.
TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing
Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan
Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233
PMCID:
PMC10237422
AbstractArticlePDF–23M
7.
APTX acts in DNA double-strand break repair in a manner distinct from XRCC4
Rikiya Imamura, Mizuki Saito, Mikio Shimada, Junya Kobayashi, Masamichi Ishiai, Yoshihisa Matsumoto
J Radiat Res. 2023 May; 64(3): 485–495. Published online 2023 Mar 20. doi: 10.1093/jrr/rrad007
PMCID:
PMC10214999
AbstractArticlePDF–1.1M
8.
Systematic analysis identifies XRCC4 as a potential immunological and prognostic biomarker associated with pan-cancer
Yang Yu, Yanyan Sun, Zhaoxian Li, Jiang Li, Dazhi Tian
BMC Bioinformatics. 2023; 24: 44. Published online 2023 Feb 10. doi: 10.1186/s12859-023-05165-8
PMCID:
PMC9921312
AbstractArticlePDF–5.5M
9.
Genome stability-related lncRNA ZFPM2-AS1 promotes tumor progression via miR-3065-5p/XRCC4 in hepatocellular carcinoma
Jie Liu, Hao Zhang, Peng Xia, Yimin Zhu, Kequan Xu, Zhisu Liu, Yufeng Yuan
Int J Oncol. 2023 Feb; 62(2): 19. Published online 2022 Dec 14. doi: 10.3892/ijo.2022.5467
PMCID:
PMC9812252
AbstractArticlePDF–16M
10.
The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis
Natalie Vaughan, Nico Scholz, Catherine Lindon, Julien D. F. Licchesi
Sci Rep. 2022; 12: 13160. Published online 2022 Aug 1. doi: 10.1038/s41598-022-16965-y
PMCID:
PMC9343455
AbstractArticlePDF–3.7M
11.
Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery
Pierre C. Havugimana, Raghuveera Kumar Goel, Sadhna Phanse, Ahmed Youssef, Dzmitry Padhorny, Sergei Kotelnikov, Dima Kozakov, Andrew Emili
Nat Commun. 2022; 13: 4043. Published online 2022 Jul 13. doi: 10.1038/s41467-022-31809-z
PMCID:
PMC9279285
AbstractArticlePDF–2.5M
12.
OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization
Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti
Science. Author manuscript; available in PMC 2022 Sep 11.
Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983
PMCID:
PMC9119736
AbstractArticlePDF–3.3M
13.
Tumor suppressor BAP1 nuclear import is governed by transportin-1
Tzu-Jing Yang, Tian-Neng Li, Rih-Sheng Huang, Max Yu-Chen Pan, Shu-Yu Lin, Steven Lin, Kuen-Phon Wu, Lily Hui-Ching Wang, Shang-Te Danny Hsu
J Cell Biol. 2022 Jun 6; 221(6): e202201094. Published online 2022 Apr 21. doi: 10.1083/jcb.202201094
PMCID:
PMC9036092
AbstractArticlePDF–4.0M
14.
Cryo-EM of NHEJ supercomplexes provides insights into DNA repair
Amanda K. Chaplin, Steven W. Hardwick, Antonia Kefala Stavridi, Christopher J. Buehl, Noah J. Goff, Virginie Ropars, Shikang Liang, Taiana Maia De Oliveira, Dimitri Y. Chirgadze, Katheryn Meek, Jean-Baptiste Charbonnier, Tom L. Blundell
Mol Cell. Author manuscript; available in PMC 2022 Aug 19.
Published in final edited form as: Mol Cell. 2021 Aug 19; 81(16): 3400–3409.e3. Published online 2021 Aug 4. doi: 10.1016/j.molcel.2021.07.005
PMCID:
PMC9006396
AbstractArticlePDF–3.0M
15.
XRCC4 and MRE11 Roles and Transcriptional Response to Repair of TALEN-Induced Double-Strand DNA Breaks
Ronald Benjamin, Atoshi Banerjee, Xiaogang Wu, Corey Geurink, Lindsay Buczek, Danielle Eames, Sara G. Trimidal, Janice M. Pluth, Martin R. Schiller
Int J Mol Sci. 2022 Jan; 23(2): 593. Published online 2022 Jan 6. doi: 10.3390/ijms23020593
PMCID:
PMC8776116
AbstractArticlePDF–3.3M
16.
USP39 promotes non-homologous end-joining repair by poly(ADP-ribose)-induced liquid demixing
Jae Jin Kim, Seo Yun Lee, Yiseul Hwang, Soyeon Kim, Jee Min Chung, Sangwook Park, Junghyun Yoon, Hansol Yun, Jae-Hoon Ji, Sunyoung Chae, Hyeseong Cho, Chan Gil Kim, Ted M Dawson, Hongtae Kim, Valina L Dawson, Ho Chul Kang
Nucleic Acids Res. 2021 Nov 8; 49(19): 11083–11102. Published online 2021 Oct 6. doi: 10.1093/nar/gkab892
PMCID:
PMC8565343
AbstractArticlePDF–11M
17.
X‐ray scattering reveals disordered linkers and dynamic interfaces in complexes and mechanisms for DNA double‐strand break repair impacting cell and cancer biology
Michal Hammel, John A. Tainer
Protein Sci. 2021 Sep; 30(9): 1735–1756. Published online 2021 Jun 5. doi: 10.1002/pro.4133
PMCID:
PMC8376411
AbstractArticlePDF–4.8M
18.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
19.
Functional analysis of XRCC4 mutations in reported microcephaly and growth defect patients in terms of radiosensitivity
Anie Day D C Asa, Rujira Wanotayan, Mukesh Kumar Sharma, Kaima Tsukada, Mikio Shimada, Yoshihisa Matsumoto
J Radiat Res. 2021 May; 62(3): 380–389. Published online 2021 Apr 12. doi: 10.1093/jrr/rrab016
PMCID:
PMC8127669
AbstractArticlePDF–755K
20.
Reciprocal regulation of RIG-I and XRCC4 connects DNA repair with RIG-I immune signaling
Guijie Guo, Ming Gao, Xiaochen Gao, Bibo Zhu, Jinzhou Huang, Xinyi Tu, Wootae Kim, Fei Zhao, Qin Zhou, Shouhai Zhu, Zheming Wu, Yuanliang Yan, Yong Zhang, Xiangyu Zeng, Qian Zhu, Ping Yin, Kuntian Luo, Jie Sun, Min Deng, Zhenkun Lou
Nat Commun. 2021; 12: 2187. Published online 2021 Apr 12. doi: 10.1038/s41467-021-22484-7
PMCID:
PMC8041803
AbstractArticlePDF–3.7M

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