PMC Links for GEO Profiles (Select 115342536) - PMC

Select item 113786131.

Apoptotic metabolites ameliorate bone aging phenotypes via TCOF1/FLVCR1-mediated mitochondrial homeostasis

Yan Qu, Bowen Meng, Simin Cai, Benyi Yang, Yifan He, Chaoran Fu, Xiangxia Li, Peiyi Li, Zeyuan Cao, Xueli Mao, Wei Teng, Songtao Shi

J Nanobiotechnology. 2024; 22: 549. Published online 2024 Sep 6. doi: 10.1186/s12951-024-02820-x

PMCID:: PMC11378613

Abstract Article PDF–15M

Select item 112933392.

Dysregulation of FLVCR1a-dependent mitochondrial calcium handling in neural progenitors causes congenital hydrocephalus

Francesca Bertino, Dibyanti Mukherjee, Massimo Bonora, Christoph Bagowski, Jeannette Nardelli, Livia Metani, Diletta Isabella Zanin Venturini, Diego Chianese, Nicolas Santander, Iris Chiara Salaroglio, Andreas Hentschel, Elisa Quarta, Tullio Genova, Arpana Arjun McKinney, Anna Lucia Allocco, Veronica Fiorito, Sara Petrillo, Giorgia Ammirata, Francesco De Giorgio, Evan Dennis, Garrett Allington, Felicitas Maier, Moneef Shoukier, Karl-Philipp Gloning, Luca Munaron, Federico Mussano, Ettore Salsano, Davide Pareyson, Maja di Rocco, Fiorella Altruda, Georgia Panagiotakos, Kristopher T. Kahle, Pierre Gressens, Chiara Riganti, Paolo P. Pinton, Andreas Roos, Thomas Arnold, Emanuela Tolosano, Deborah Chiabrando

Cell Rep Med. 2024 Jul 16; 5(7): 101647. Published online 2024 Jul 16. doi: 10.1016/j.xcrm.2024.101647

PMCID:: PMC11293339

Abstract Article PDF–9.2M

Select item 108871983.

FLVCR1a Controls Cellular Cholesterol Levels through the Regulation of Heme Biosynthesis and Tricarboxylic Acid Cycle Flux in Endothelial Cells

Marta Manco, Giorgia Ammirata, Sara Petrillo, Francesco De Giorgio, Simona Fontana, Chiara Riganti, Paolo Provero, Sharmila Fagoonee, Fiorella Altruda, Emanuela Tolosano

Biomolecules. 2024 Feb; 14(2): 149. Published online 2024 Jan 26. doi: 10.3390/biom14020149

PMCID:: PMC10887198

Abstract Article PDF–4.7M

Select item 107693504.

Identification of new ciliary signaling pathways in the brain and insights into neurological disorders

Abdelhalim Loukil, Emma Ebright, Akiyoshi Uezu, Yudong Gao, Scott H Soderling, Sarah C. Goetz

Version 1. bioRxiv. Preprint. 2023 Dec 21. doi: 10.1101/2023.12.20.572700

PMCID:: PMC10769350

Abstract Article PDF–11M

Select item 103675825.

Integrative genetic analysis identifies FLVCR1 as a plasma membrane choline transporter in mammals

Timothy C. Kenny, Artem Khan, Yeeun Son, Lishu Yue, Søren Heissel, Anurag Sharma, H. Amalia Pasolli, Yuyang Liu, Eric R. Gamazon, Hanan Alwaseem, Richard K. Hite, KIvanç Birsoy

Cell Metab. Author manuscript; available in PMC 2024 Jun 6.

Published in final edited form as: Cell Metab. 2023 Jun 6; 35(6): 1057–1071.e12. Published online 2023 Apr 25. doi: 10.1016/j.cmet.2023.04.003

PMCID:: PMC10367582

Abstract Article PDF–2.9M

Select item 103289046.

Endothelial cells require functional FLVCR1a during developmental and adult angiogenesis

Sara Petrillo, F. De Giorgio, F. Bertino, F. Garello, V. Bitonto, D. L. Longo, S. Mercurio, G. Ammirata, A. L. Allocco, V. Fiorito, D. Chiabrando, F. Altruda, E. Terreno, P. Provero, L. Munaron, T. Genova, A. Nóvoa, A. R. Carlos, S. Cardoso, M. Mallo, M. P. Soares, E. Tolosano

Angiogenesis. 2023; 26(3): 365–384. Published online 2023 Jan 11. doi: 10.1007/s10456-023-09865-w

PMCID:: PMC10328904

Abstract Article PDF–2.7M

Select item 74159917.

BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING)

Kou Motani, Hidetaka Kosako

J Biol Chem. 2020 Aug 7; 295(32): 11174–11183. Published online 2020 Jun 17. doi: 10.1074/jbc.RA120.014323

PMCID:: PMC7415991

Abstract Article PDF–2.0M

Select item 58642158.

Heme accumulation in endothelial cells impairs angiogenesis by triggering paraptosis

Sara Petrillo, Deborah Chiabrando, Tullio Genova, Veronica Fiorito, Giada Ingoglia, Francesca Vinchi, Federico Mussano, Stefano Carossa, Lorenzo Silengo, Fiorella Altruda, Giorgio Roberto Merlo, Luca Munaron, Emanuela Tolosano

Cell Death Differ. 2018 Mar; 25(3): 573–588. Published online 2017 Dec 11. doi: 10.1038/s41418-017-0001-7

PMCID:: PMC5864215

Abstract Article PDF–8.5M

Select item 47835529.

TLR Stimulation Dynamically Regulates Heme and Iron Export Gene Expression in Macrophages

Mary Philip, Edison Y. Chiu, Adeline M. Hajjar, Janis L. Abkowitz

J Immunol Res. 2016; 2016: 4039038. Published online 2016 Feb 24. doi: 10.1155/2016/4039038

PMCID:: PMC4783552

Abstract Article PDF–760K

Select item 466577410.

Coordinate expression of heme and globin is essential for effective erythropoiesis

Raymond T. Doty, Susan R. Phelps, Christina Shadle, Marilyn Sanchez-Bonilla, Siobán B. Keel, Janis L. Abkowitz

J Clin Invest. 2015 Dec 1; 125(12): 4681–4691. Published online 2015 Nov 9. doi: 10.1172/JCI83054

PMCID:: PMC4665774

Abstract Article PDF–1.1M

Select item 432386611.

Heme exporter FLVCR is required for T cell development and peripheral survival

Mary Philip, Scott A. Funkhouser, Edison Y. Chiu, Susan R. Phelps, Jeffrey J. Delrow, James Cox, Pamela J. Fink, Janis L. Abkowitz

J Immunol. Author manuscript; available in PMC 2016 Feb 15.

Published in final edited form as: J Immunol. 2015 Feb 15; 194(4): 1677–1685. Published online 2015 Jan 12. doi: 10.4049/jimmunol.1402172

PMCID:: PMC4323866

Abstract Article PDF–1.9M

Select item 400044012.

Heme Exporter FLVCR1a Regulates Heme Synthesis and Degradation and Controls Activity of Cytochromes P450

Francesca Vinchi, Giada Ingoglia, Deborah Chiabrando, Sonia Mercurio, Emilia Turco, Lorenzo Silengo, Fiorella Altruda, Emanuela Tolosano

Gastroenterology. 2014 May; 146(5): 1325–1338. doi: 10.1053/j.gastro.2014.01.053

PMCID:: PMC4000440

Abstract Article

Select item 379900213.

FLVCR is necessary for erythroid maturation, may contribute to platelet maturation, but is dispensable for normal hematopoietic stem cell function

John C. H. Byon, Jing Chen, Raymond T. Doty, Janis L. Abkowitz

Blood. 2013 Oct 17; 122(16): 2903–2910. Prepublished online 2013 Sep 10. doi: 10.1182/blood-2012-10-465104

PMCID:: PMC3799002

Abstract Article

Select item 353353414.

The mitochondrial heme exporter FLVCR1b mediates erythroid differentiation

Deborah Chiabrando, Samuele Marro, Sonia Mercurio, Carlotta Giorgi, Sara Petrillo, Francesca Vinchi, Veronica Fiorito, Sharmila Fagoonee, Annalisa Camporeale, Emilia Turco, Giorgio R. Merlo, Lorenzo Silengo, Fiorella Altruda, Paolo Pinton, Emanuela Tolosano

J Clin Invest. 2012 Dec 3; 122(12): 4569–4579. Published online 2012 Nov 26. doi: 10.1172/JCI62422

PMCID:: PMC3533534

Abstract Article PDF–2.7M

Select item 330243515.

Polarized Distribution of Heme Transporters in Retinal Pigment Epithelium and Their Regulation in the Iron-Overload Disease Hemochromatosis

Jaya P. Gnana-Prakasam, Sushma K. Reddy, Rajalakshmi Veeranan-Karmegam, Sylvia B. Smith, Pamela M. Martin, Vadivel Ganapathy

Invest Ophthalmol Vis Sci. 2011 Nov; 52(12): 9279–9286. Published online 2011 Nov 29. doi: 10.1167/iovs.11-8264

PMCID:: PMC3302435

Abstract Article PDF–2.6M

Select item 317805916.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 31099217.

RIKEN Integrated Sequence Analysis (RISA) System—384-Format Sequencing Pipeline with 384 Multicapillary Sequencer

Kazuhiro Shibata, Masayoshi Itoh, Katsunori Aizawa, Sumiharu Nagaoka, Nobuya Sasaki, Piero Carninci, Hideaki Konno, Junichi Akiyama, Katsuo Nishi, Tokuji Kitsunai, Hideo Tashiro, Mari Itoh, Noriko Sumi, Yoshiyuki Ishii, Shin Nakamura, Makoto Hazama, Tsutomu Nishine, Akira Harada, Rintaro Yamamoto, Hiroyuki Matsumoto, Sumito Sakaguchi, Takashi Ikegami, Katsuya Kashiwagi, Syuji Fujiwake, Kouji Inoue, Yoshiyuki Togawa, Masaki Izawa, Eiji Ohara, Masanori Watahiki, Yuko Yoneda, Tomokazu Ishikawa, Kaori Ozawa, Takumi Tanaka, Shuji Matsuura, Jun Kawai, Yasushi Okazaki, Masami Muramatsu, Yorinao Inoue, Akira Kira, Yoshihide Hayashizaki

Genome Res. 2000 Nov; 10(11): 1757–1771. doi: 10.1101/gr.152600

PMCID:: PMC310992

Abstract Article PDF–3.4M

Select item 31098018.

Normalization and Subtraction of Cap-Trapper-Selected cDNAs to Prepare Full-Length cDNA Libraries for Rapid Discovery of New Genes

Piero Carninci, Yuko Shibata, Norihito Hayatsu, Yuichi Sugahara, Kazuhiro Shibata, Masayoshi Itoh, Hideaki Konno, Yasushi Okazaki, Masami Muramatsu, Yoshihide Hayashizaki

Genome Res. 2000 Oct; 10(10): 1617–1630. doi: 10.1101/gr.145100

PMCID:: PMC310980

Abstract Article PDF–1.4M

Select item 13924119.

Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences

Mammalian Gene Collection (MGC) Program Team

Proc Natl Acad Sci U S A. 2002 Dec 24; 99(26): 16899–16903. Published online 2002 Dec 11. doi: 10.1073/pnas.242603899

PMCID:: PMC139241

Abstract Article PDF–118K

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