PMC Links for GEO Profiles (Select 115314616) - PMC

Result Filters

Links from GEO Profiles

Items: 1 to 20 of 48

<< First< Prev

Page of 3

Select item 96396601.

Liver-heart cross-talk mediated by coagulation factor XI protects against heart failure

Yang Cao, Yuchen Wang, Zhenqi Zhou, Calvin Pan, Ling Jiang, Zhiqiang Zhou, Yonghong Meng, Sarada Charugundla, Tao Li, Hooman Allayee, Marcus M. Seldin, Aldons J. Lusis

Science. Author manuscript; available in PMC 2022 Nov 7.

Published in final edited form as: Science. 2022 Sep 23; 377(6613): 1399–1406. Published online 2022 Sep 22. doi: 10.1126/science.abn0910

PMCID:: PMC9639660

Abstract Article PDF–1.9M

Select item 82006772.

Effect of CpG Depletion of Vector Genome on CD8⁺ T Cell Responses in AAV Gene Therapy

Thais B. Bertolini, Jamie L. Shirley, Irene Zolotukhin, Xin Li, Tsuneyasu Kaisho, Weidong Xiao, Sandeep R. P. Kumar, Roland W. Herzog

Front Immunol. 2021; 12: 672449. Published online 2021 May 31. doi: 10.3389/fimmu.2021.672449

PMCID:: PMC8200677

Abstract Article PDF–2.8M

Select item 78104123.

Evaluating the potential benefits of the extravascular pool of factor IX

David Lillicrap

Blood Coagul Fibrinolysis. 2021 Jan; 32(1): 68–69. Published online 2021 Nov 23. doi: 10.1097/MBC.0000000000000969

PMCID:: PMC7810412

Article PDF–72K

Select item 67835544.

Hemophilia A and B mice, but not VWF^−/−mice, display bone defects in congenital development and remodeling after injury

Sarah Taves, Junjiang Sun, Eric W. Livingston, Xin Chen, Jerome Amiaud, Regis Brion, William B. Hannah, Ted A. Bateman, Dominique Heymann, Paul E. Monahan

Sci Rep. 2019; 9: 14428. Published online 2019 Oct 8. doi: 10.1038/s41598-019-50787-9

PMCID:: PMC6783554

Abstract Article PDF–4.0M

Select item 60783545.

Coagulation factor 9-deficient mice are protected against dextran sulfate sodium-induced colitis

Avinash Khandagale, Jens M. Kittner, Amrit Mann, Stefanie Ascher, Bettina Kollar, Christoph Reinhardt

Biol Open. 2018 Jul 15; 7(7): bio034140. Published online 2018 Jun 26. doi: 10.1242/bio.034140

PMCID:: PMC6078354

Abstract Article PDF–1.0M

Select item 59872506.

Autologous and Heterologous Cell Therapy for Hemophilia B toward Functional Restoration of Factor IX

Suvasini Ramaswamy, Nina Tonnu, Tushar Menon, Benjamin M. Lewis, Kevin T. Green, Derek Wampler, Paul E. Monahan, Inder M. Verma

Cell Rep. Author manuscript; available in PMC 2018 Jun 5.

Published in final edited form as: Cell Rep. 2018 May 1; 23(5): 1565–1580. doi: 10.1016/j.celrep.2018.03.121

PMCID:: PMC5987250

Abstract Article PDF–2.5M

Select item 59821147.

The Anticoagulant Protein S Targets the Factor IXa Heparin-Binding Exosite to Prevent Thrombosis

William E. Plautz, Vijaya Satish Sekhar Pilli, Brian C. Cooley, Rima Chattopadhyay, Pamela R. Westmark, Todd Getz, David Paul, Wolfgang Bergmeier, John P. Sheehan, Rinku Majumder

Arterioscler Thromb Vasc Biol. Author manuscript; available in PMC 2019 Apr 1.

Published in final edited form as: Arterioscler Thromb Vasc Biol. 2018 Apr; 38(4): 816–828. Published online 2018 Feb 1. doi: 10.1161/ATVBAHA.117.310588

PMCID:: PMC5982114

Abstract Article PDF–2.6M

Select item 58924278.

Tissue factor Deficiency Increases Alveolar Hemorrhage and Death in Influenza A Infected Mice

Silvio Antoniak, Kohei Tatsumi, Yohei Hisada, J. Justin Milner, Scott D. Neidich, Ciara M. Shaver, Rafal Pawlinski, Melinda A. Beck, Julie A. Bastarache, Nigel Mackman

J Thromb Haemost. Author manuscript; available in PMC 2018 Apr 10.

Published in final edited form as: J Thromb Haemost. 2016 Jun; 14(6): 1238–1248. Published online 2016 Apr 5. doi: 10.1111/jth.13307

Correction in:: J Thromb Haemost. 2016 Dec; 14(12): 2565.

PMCID:: PMC5892427

Abstract Article PDF–1.7M

Select item 58652309.

Targeting anticoagulant protein S to improve hemostasis in hemophilia

Raja Prince, Luca Bologna, Mirko Manetti, Daniela Melchiorre, Irene Rosa, Natacha Dewarrat, Silvia Suardi, Poorya Amini, José A. Fernández, Laurent Burnier, Claudia Quarroz, Maria Desiré Reina Caro, Yasuhiro Matsumura, Johanna A. Kremer Hovinga, John H. Griffin, Hans-Uwe Simon, Lidia Ibba-Manneschi, François Saller, Sara Calzavarini, Anne Angelillo-Scherrer

Blood. 2018 Mar 22; 131(12): 1360–1371. Prepublished online 2018 Jan 9. doi: 10.1182/blood-2017-09-800326

PMCID:: PMC5865230

Abstract Article

Select item 582118810.

VKOR paralog VKORC1L1 supports vitamin K–dependent protein carboxylation in vivo

Julie Lacombe, Mark A. Rishavy, Kathleen L. Berkner, Mathieu Ferron

JCI Insight. 2018 Jan 11; 3(1): e96501. Published online 2018 Jan 11. doi: 10.1172/jci.insight.96501

PMCID:: PMC5821188

Abstract Article PDF–2.7M

Select item 566631011.

Genome editing for scalable production of alloantigen‐free lentiviral vectors for in vivo gene therapy

Michela Milani, Andrea Annoni, Sara Bartolaccini, Mauro Biffi, Fabio Russo, Tiziano Di Tomaso, Andrea Raimondi, Johannes Lengler, Michael C Holmes, Friedrich Scheiflinger, Angelo Lombardo, Alessio Cantore, Luigi Naldini

EMBO Mol Med. 2017 Nov; 9(11): 1558–1573. Published online 2017 Aug 23. doi: 10.15252/emmm.201708148

PMCID:: PMC5666310

Abstract Article PDF–1.5M

Select item 539162312.

Abnormal joint and bone wound healing in hemophilia mice is improved by extending factor IX activity after hemarthrosis

Junjiang Sun, Baolai Hua, Eric W. Livingston, Sarah Taves, Peter B. Johansen, Maureane Hoffman, Mirella Ezban, Dougald M. Monroe, Ted A. Bateman, Paul E. Monahan

Blood. 2017 Apr 13; 129(15): 2161–2171. Prepublished online 2016 Dec 30. doi: 10.1182/blood-2016-08-734053

PMCID:: PMC5391623

Abstract Article

Select item 534759613.

Systemic delivery of factor IX messenger RNA for protein replacement therapy

Suvasini Ramaswamy, Nina Tonnu, Kiyoshi Tachikawa, Pattraranee Limphong, Jerel B. Vega, Priya P. Karmali, Pad Chivukula, Inder M. Verma

Proc Natl Acad Sci U S A. 2017 Mar 7; 114(10): E1941–E1950. Published online 2017 Feb 15. doi: 10.1073/pnas.1619653114

PMCID:: PMC5347596

Abstract Article PDF–1.4M

Select item 529130114.

Prophylactic efficacy of BeneFIX vs Alprolix in hemophilia B mice

Brian Cooley, William Funkhouser, Dougald Monroe, Ashley Ezzell, David M. Mann, Feng-Chang Lin, Paul E. Monahan, Darrel W. Stafford

Blood. 2016 Jul 14; 128(2): 286–292. Prepublished online 2016 Apr 22. doi: 10.1182/blood-2016-01-696104

PMCID:: PMC5291301

Abstract Article

Select item 512583215.

CRISPR/Cas9‐mediated somatic correction of a novel coagulator factor IX gene mutation ameliorates hemophilia in mouse

Yuting Guan, Yanlin Ma, Qi Li, Zhenliang Sun, Lie Ma, Lijuan Wu, Liren Wang, Li Zeng, Yanjiao Shao, Yuting Chen, Ning Ma, Wenqing Lu, Kewen Hu, Honghui Han, Yanhong Yu, Yuanhua Huang, Mingyao Liu, Dali Li

EMBO Mol Med. 2016 May; 8(5): 477–488. Published online 2016 Mar 10. doi: 10.15252/emmm.201506039

PMCID:: PMC5125832

Abstract Article PDF–1.9M

Select item 460001716.

In vivo genome editing of the albumin locus as a platform for protein replacement therapy

Rajiv Sharma, Xavier M. Anguela, Yannick Doyon, Thomas Wechsler, Russell C. DeKelver, Scott Sproul, David E. Paschon, Jeffrey C. Miller, Robert J. Davidson, David Shivak, Shangzhen Zhou, Julianne Rieders, Philip D. Gregory, Michael C. Holmes, Edward J. Rebar, Katherine A. High

Blood. 2015 Oct 8; 126(15): 1777–1784. Prepublished online 2015 Aug 21. doi: 10.1182/blood-2014-12-615492

PMCID:: PMC4600017

Abstract Article

Select item 449220017.

Hemostatic agents of broad applicability produced by selective tuning of factor Xa zymogenicity

Lacramioara Ivanciu, Rodney M. Camire

Blood. 2015 Jul 2; 126(1): 94–102. Prepublished online 2015 Apr 20. doi: 10.1182/blood-2015-03-634329

PMCID:: PMC4492200

Abstract Article

Select item 439201018.

Plant-based oral tolerance to hemophilia therapy employs a complex immune regulatory response including LAP⁺CD4⁺ T cells

Xiaomei Wang, Jin Su, Alexandra Sherman, Geoffrey L. Rogers, Gongxian Liao, Brad E. Hoffman, Kam W. Leong, Cox Terhorst, Henry Daniell, Roland W. Herzog

Blood. 2015 Apr 9; 125(15): 2418–2427. Prepublished online 2015 Feb 19. doi: 10.1182/blood-2014-08-597070