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Items: 1 to 20 of 521

1.
The androgen receptor in mesenchymal progenitors regulates skeletal muscle mass via Igf1 expression in male mice
Hiroshi Sakai, Hideaki Uno, Harumi Yamakawa, Kaori Tanaka, Aoi Ikedo, Akiyoshi Uezumi, Yasuyuki Ohkawa, Yuuki Imai
Proc Natl Acad Sci U S A. 2024 Sep 24; 121(39): e2407768121. Published online 2024 Sep 18. doi: 10.1073/pnas.2407768121
PMCID:
PMC11441553
AbstractArticlePDF–1.1M
2.
Targeting IGF1/IGF1r signaling relieve pain and autophagic dysfunction in NTG-induced chronic migraine model of mice
Tianxiao Wang, Chenlu Zhu, Kaibo zhang, Jinggui Gao, Yunhao Xu, Chenyang Duan, Shouyi Wu, Cheng Peng, Jisong Guan, Yonggang Wang
J Headache Pain. 2024; 25(1): 156. Published online 2024 Sep 20. doi: 10.1186/s10194-024-01864-6
Correction in:
J Headache Pain. 2024; 25(1): 173.
PMCID:
PMC11414239
AbstractArticlePDF–8.2M
3.
SPAG7 deletion causes intrauterine growth restriction, resulting in adulthood obesity and metabolic dysfunction
Stephen E Flaherty, III, Olivier Bezy, Brianna LaCarubba Paulhus, LouJin Song, Mary Piper, Jincheng Pang, Yoson Park, Shoh Asano, Yu-Chin Lien, John D Griffin, Andrew Robertson, Alan Opsahl, Dinesh Hirenallur Shanthappa, Youngwook Ahn, Evanthia Pashos, Rebecca A Simmons, Morris J Birnbaum, Zhidan Wu
eLife. 2024; 12: RP91114. Published online 2024 Jul 26. doi: 10.7554/eLife.91114
PMCID:
PMC11281781
AbstractArticlePDF–3.8M
4.
Tmem263 deletion disrupts the GH/IGF-1 axis and causes dwarfism and impairs skeletal acquisition
Dylan C Sarver, Jean Garcia-Diaz, Muzna Saqib, Ryan C Riddle, G William Wong
eLife. 2024; 12: RP90949. Published online 2024 Jan 19. doi: 10.7554/eLife.90949
PMCID:
PMC10945605
AbstractArticlePDF–11M
5.
Identification of IGF-1 Effects on White Adipose Tissue and Hippocampus in Alzheimer’s Disease Mice via Transcriptomic and Cellular Analysis
Young-Kook Kim, Danbi Jo, Archana Arjunan, Yeongseo Ryu, Yeong-Hwan Lim, Seo Yoon Choi, Hee Kyung Kim, Juhyun Song
Int J Mol Sci. 2024 Mar; 25(5): 2567. Published online 2024 Feb 22. doi: 10.3390/ijms25052567
PMCID:
PMC10931577
AbstractArticlePDF–6.1M
6.
Mrc1+ macrophage-derived IGF1 mitigates crystal nephropathy by promoting renal tubule cell proliferation via the AKT/Rb signaling pathway
Linxi Huang, Wei Chen, Zhuojing Tan, Yunxiao Huang, Xinji Gu, Lantian Liu, Hongxia Zhang, Yihan Shi, Jiarong Ding, Chengjian Zheng, Zhiyong Guo, Bing Yu
Theranostics. 2024; 14(4): 1764–1780. Published online 2024 Feb 17. doi: 10.7150/thno.89174
PMCID:
PMC10879870
AbstractArticlePDF–17M
7.
Microglia-Derived Insulin-like Growth Factor 1 Is Critical for Neurodevelopment
Dominika Rusin, Lejla Vahl Becirovic, Gabriela Lyszczarz, Martin Krueger, Anouk Benmamar-Badel, Cecilie Vad Mathiesen, Eydís Sigurðardóttir Schiöth, Kate Lykke Lambertsen, Agnieszka Wlodarczyk
Cells. 2024 Jan; 13(2): 184. Published online 2024 Jan 18. doi: 10.3390/cells13020184
PMCID:
PMC10813844
AbstractArticlePDF–2.9M
8.
Combination of blockade of endothelin signalling and compensation of IGF1 expression protects the retina from degeneration
Naoya Shigesada, Naoya Shikada, Manabu Shirai, Michinori Toriyama, Fumiaki Higashijima, Kazuhiro Kimura, Toru Kondo, Yasumasa Bessho, Takuma Shinozuka, Noriaki Sasai
Cell Mol Life Sci. 2024 Dec; 81(1): 51. Published online 2024 Jan 22. doi: 10.1007/s00018-023-05087-x
PMCID:
PMC10803390
AbstractArticlePDF–3.2M
9.
A multi-stem cell basis for craniosynostosis and calvarial mineralization
Seoyeon Bok, Alisha R. Yallowitz, Jun Sun, Jason McCormick, Michelle Cung, Lingling Hu, Sarfaraz Lalani, Zan Li, Branden R. Sosa, Tomas Baumgartner, Paul Byrne, Tuo Zhang, Kyle W. Morse, Fatma F. Mohamed, Chunxi Ge, Renny T. Franceschi, Randy T. Cowling, Barry H. Greenberg, David J. Pisapia, Thomas A. Imahiyerobo, Jr, Shenela Lakhani, M. Elizabeth Ross, Caitlin E. Hoffman, Shawon Debnath, Matthew B. Greenblatt
Nature. Author manuscript; available in PMC 2024 Mar 20.
Published in final edited form as: Nature. 2023 Sep; 621(7980): 804–812. Published online 2023 Sep 20. doi: 10.1038/s41586-023-06526-2
PMCID:
PMC10799660
AbstractArticlePDF–15M
10.
Role of IGF-I Signaling in Regulating Osteoclastogenesis
Yongmei Wang, Shigeki Nishida, Hashem Z Elalieh, Roger K Long, Bernard P Halloran, Daniel D Bikle
J Bone Miner Res. Author manuscript; available in PMC 2023 Dec 15.
Published in final edited form as: J Bone Miner Res. 2006 Sep; 21(9): 1350–1358. doi: 10.1359/jbmr.060610
PMCID:
PMC10723110
AbstractArticlePDF–2.0M
11.
Insulin-Like Growth Factor-I Is Essential for Embryonic Bone Development
Yongmei Wang, Shigeki Nishida, Takeshi Sakata, Hashem Z. Elalieh, Wenhan Chang, Bernard P. Halloran, Steven B. Doty, Daniel D. Bikle
Endocrinology. Author manuscript; available in PMC 2023 Nov 14.
Published in final edited form as: Endocrinology. 2006 Oct; 147(10): 4753–4761. Published online 2006 Jul 20. doi: 10.1210/en.2006-0196
PMCID:
PMC10645399
AbstractArticlePDF–2.8M
12.
Cartilage-specific Sirt6 deficiency represses IGF-1 and enhances osteoarthritis severity in mice
John A Collins, C James Kim, Ashley Coleman, Abreah Little, Matheus M Perez, Emily J Clarke, Brian Diekman, Mandy J Peffers, Susanna Chubinskaya, Ryan E Tomlinson, Theresa A Freeman, Richard F Loeser
Ann Rheum Dis. 2023 Nov; 82(11): 1464–1473. Published online 2023 Aug 7. doi: 10.1136/ard-2023-224385
PMCID:
PMC10579179
AbstractArticlePDF–4.1M
13.
Insulin-like Growth Factor-1 Synergizes with IL-2 to Induce Homeostatic Proliferation of Regulatory T Cells
Melanie R. Shapiro, Leeana D. Peters, Matthew E. Brown, Cecilia Cabello-Kindelan, Amanda L. Posgai, Allison L. Bayer, Todd M. Brusko
J Immunol. 2023 Oct 1; 211(7): 1108–1122. Published online 2023 Aug 18. doi: 10.4049/jimmunol.2200651
PMCID:
PMC10511790
AbstractArticlePDF–3.3M
14.
Accumulation of endogenous adenosine improves cardiomyocyte metabolism via epigenetic reprogramming in an ischemia-reperfusion model
Peng Wang, Rifeng Gao, Tingting Wu, Jinyan Zhang, Xiaolei Sun, Fan Fan, Cong Wang, Sanli Qian, Bingyu Li, Yunzeng Zou, Yuqing Huo, John Fassett, Yingjie Chen, Junbo Ge, Aijun Sun
Redox Biol. 2023 Nov; 67: 102884. Published online 2023 Sep 13. doi: 10.1016/j.redox.2023.102884
PMCID:
PMC10507380
AbstractArticlePDF–11M
15.
Macrophage-mediated extracellular matrix remodeling controls host Staphylococcus aureus susceptibility in the skin
Benjamin Voisin, Vinod Nadella, Thomas Doebel, Shubham Goel, Keiko Sakamoto, Otgonzaya Ayush, Jay-Hyun Jo, Michael C. Kelly, Tetsuro Kobayashi, Jean X. Jiang, Ying Hu, Chunhua Yan, Keisuke Nagao
Immunity. Author manuscript; available in PMC 2024 Jul 11.
Published in final edited form as: Immunity. 2023 Jul 11; 56(7): 1561–1577.e9. Published online 2023 Jul 3. doi: 10.1016/j.immuni.2023.06.006
PMCID:
PMC10467568
AbstractArticlePDF–3.5M
16.
Delayed skeletal development and IGF-1 deficiency in a mouse model of lysinuric protein intolerance
Bridget M. Stroup, Xiaohui Li, Sara Ho, Haonan Zhouyao, Yuqing Chen, Safa Ani, Brian Dawson, Zixue Jin, Ronit Marom, Ming-Ming Jiang, Isabel Lorenzo, Daniel Rosen, Denise Lanza, Nathalie Aceves, Sara Koh, John R. Seavitt, Jason D. Heaney, Brendan Lee, Lindsay C. Burrage
Dis Model Mech. 2023 Aug 1; 16(8): dmm050118. Published online 2023 Aug 17. doi: 10.1242/dmm.050118
PMCID:
PMC10445726
AbstractArticle
17.
Osteoclast-derived IGF1 induces RANKL production in osteocytes and contributes to pagetic lesion formation
Kazuaki Miyagawa, Hirofumi Tenshin, Patrick L. Mulcrone, Jesus Delgado-Calle, Mark A. Subler, Jolene J. Windle, John M. Chirgwin, G. David Roodman, Noriyoshi Kurihara
JCI Insight. 2023 Jul 24; 8(14): e159838. Published online 2023 Jul 24. doi: 10.1172/jci.insight.159838
PMCID:
PMC10443794
AbstractArticlePDF–3.5M
18.
TRIM28 modulates nuclear receptor signaling to regulate uterine function
Rong Li, Tianyuan Wang, Ryan M. Marquardt, John P. Lydon, San-Pin Wu, Francesco J. DeMayo
Nat Commun. 2023; 14: 4605. Published online 2023 Aug 1. doi: 10.1038/s41467-023-40395-7
PMCID:
PMC10393996
AbstractArticlePDF–11M
19.
Insulin-Like Growth Factor1 Preserves Gastric Pacemaker Cells and Motor Function in Aging via ERK1/2 Activation
Vy Truong Thuy Nguyen, Negar Taheri, Egan L. Choi, Todd A. Kellogg, David R. Linden, Yujiro Hayashi
Cell Mol Gastroenterol Hepatol. 2023; 16(3): 369–383. Published online 2023 Jun 8. doi: 10.1016/j.jcmgh.2023.06.002
PMCID:
PMC10372898
AbstractArticlePDF–4.0M
20.
Brain IGF-I regulates LTP, spatial memory, and sexual dimorphic behavior
Raquel Herrero-Labrador, Joaquín Fernández-Irigoyen, Rebeca Vecino, Candela González-Arias, Karina Ausín, Inmaculada Crespo, Francisco J Fernández Acosta, Vanesa Nieto-Estévez, M José Román, Gertrudis Perea, Ignacio Torres-Alemán, Enrique Santamaría, Carlos Vicario
Life Sci Alliance. 2023 Oct; 6(10): e202201691. Published online 2023 Jul 18. doi: 10.26508/lsa.202201691
PMCID:
PMC10355288
AbstractArticlePDF–4.9M

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