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Select item 111470861.

Intragenic complementation and the structure and function of argininosuccinate lyase

B. Yu, P. L. Howell

Cell Mol Life Sci. 2000 Oct; 57(11): 1637–1651. doi: 10.1007/PL00000646

PMCID:: PMC11147086

Abstract Article PDF–1.1M

Select item 105441972.

Argininosuccinate lyase deficiency causes blood-brain barrier disruption via nitric oxide–mediated dysregulation of claudin expression

Jordan Kho, Urszula Polak, Ming-Ming Jiang, John D. Odom, Jill V. Hunter, Saima M. Ali, Lindsay C. Burrage, Sandesh C.S. Nagamani, Robia G. Pautler, Hannah P. Thompson, Akihiko Urayama, Zixue Jin, Brendan Lee

JCI Insight. 2023 Sep 8; 8(17): e168475. Published online 2023 Sep 8. doi: 10.1172/jci.insight.168475

PMCID:: PMC10544197

Abstract Article PDF–1.8M

Select item 96658853.

Mapping Brain Gene Coexpression in Daytime Transcriptomes Unveils Diurnal Molecular Networks and Deciphers Perturbation Gene Signatures

Nan Wang, Peter Langfelder, Matthew Stricos, Lalini Ramanathan, Jeffrey B. Richman, Raymond Vaca, Mary Plascencia, Xiaofeng Gu, Shasha Zhang, T. Katherine Tamai, Liguo Zhang, Fuying Gao, Koliane Ouk, Xiang Lu, Leonya Ivanov, Tom Vogt, Qing Richard Lu, A. Jennifer Morton, Christopher Colwell, Jeffrey S. Aaronson, Jim Rosinski, Steve Horvath, X. William Yang

Neuron. Author manuscript; available in PMC 2023 Oct 19.

Published in final edited form as: Neuron. 2022 Oct 19; 110(20): 3318–3338.e9. doi: 10.1016/j.neuron.2022.09.028

PMCID:: PMC9665885

Abstract Article PDF–4.5M

Select item 88205924.

L-arginine transfer from antigen presenting cells sustains CD4⁺ T cell viability and proliferation

Rebecca R. Crowther, Stephanie M. Schmidt, Shannon M. Lange, Melanie C. McKell, Michelle C. Robillard, Junfang Zhao, Wendy D. Haffey, Michael A. Wyder, Kenneth D. Greis, Kenneth D. R. Setchell, Joseph E. Qualls

J Immunol. Author manuscript; available in PMC 2023 Feb 15.

Published in final edited form as: J Immunol. 2022 Feb 15; 208(4): 793–798. Published online 2022 Jan 31. doi: 10.4049/jimmunol.2100652

PMCID:: PMC8820592

Abstract Article PDF–1.0M

Select item 81605135.

Promotion of Anti-Tuberculosis Macrophage Activity by L-Arginine in the Absence of Nitric Oxide

Melanie C. McKell, Rebecca R. Crowther, Stephanie M. Schmidt, Michelle C. Robillard, Rachel Cantrell, Maria A. Lehn, Edith M. Janssen, Joseph E. Qualls

Front Immunol. 2021; 12: 653571. Published online 2021 May 14. doi: 10.3389/fimmu.2021.653571

PMCID:: PMC8160513

Abstract Article PDF–7.4M

Select item 79387706.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 78634007.

Beclin‐1‐mediated activation of autophagy improves proximal and distal urea cycle disorders

Leandro R Soria, Sonam Gurung, Giulia De Sabbata, Dany P Perocheau, Angela De Angelis, Gemma Bruno, Elena Polishchuk, Debora Paris, Paola Cuomo, Andrea Motta, Michael Orford, Youssef Khalil, Simon Eaton, Philippa B Mills, Simon N Waddington, Carmine Settembre, Andrés F Muro, Julien Baruteau, Nicola Brunetti‐Pierri

EMBO Mol Med. 2021 Feb 5; 13(2): e13158. Published online 2020 Dec 28. doi: 10.15252/emmm.202013158

PMCID:: PMC7863400

Abstract Article PDF–2.6M

Select item 74159918.

BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING)

Kou Motani, Hidetaka Kosako

J Biol Chem. 2020 Aug 7; 295(32): 11174–11183. Published online 2020 Jun 17. doi: 10.1074/jbc.RA120.014323

PMCID:: PMC7415991

Abstract Article PDF–2.0M

Select item 71011349.

Chronic liver disease and impaired hepatic glycogen metabolism in argininosuccinate lyase deficiency

Lindsay C. Burrage, Simran Madan, Xiaohui Li, Saima Ali, Mahmoud Mohammad, Bridget M. Stroup, Ming-Ming Jiang, Racel Cela, Terry Bertin, Zixue Jin, Jian Dai, Danielle Guffey, Milton Finegold, Members of the Urea Cycle Disorders Consortium (UCDC), Sandesh Nagamani, Charles G. Minard, Juan Marini, Prakash Masand, Deborah Schady, Benjamin L. Shneider, Daniel H. Leung, Deeksha Bali, Brendan Lee

JCI Insight. 2020 Feb 27; 5(4): e132342. Published online 2020 Feb 27. doi: 10.1172/jci.insight.132342

PMCID:: PMC7101134

Abstract Article PDF–4.4M

Select item 640124710.

L-arginine synthesis from L-citrulline in myeloid cells drives host defense against mycobacteria in vivo

Shannon M. Lange, Melanie C. McKell, Stephanie M. Schmidt, Junfang Zhao, Rebecca R. Crowther, Lisa C. Green, Rebecca L. Bricker, Eusondia Arnett, S. Eleonore Köhler, Larry S. Schlesinger, Kenneth D. R. Setchell, Joseph E. Qualls

J Immunol. Author manuscript; available in PMC 2020 Mar 15.

Published in final edited form as: J Immunol. 2019 Mar 15; 202(6): 1747–1754. Published online 2019 Feb 1. doi: 10.4049/jimmunol.1801569

PMCID:: PMC6401247

Abstract Article PDF–1.4M

Select item 626277711.

LCP1 preferentially binds clasped αMβ2 integrin and attenuates leukocyte adhesion under flow

Hui-yuan Tseng, Anna V. Samarelli, Patricia Kammerer, Sarah Scholze, Tilman Ziegler, Roland Immler, Roy Zent, Markus Sperandio, Charles R. Sanders, Reinhard Fässler, Ralph T. Böttcher

J Cell Sci. 2018 Nov 15; 131(22): jcs218214. Published online 2018 Nov 21. doi: 10.1242/jcs.218214

PMCID:: PMC6262777

Abstract Article

Select item 624418312.

Complementary proteomics strategies capture an ataxin-1 interactome in Neuro-2a cells

Sunyuan Zhang, Nicholas A. Williamson, Marie A. Bogoyevitch

Sci Data. 2018; 5: 180262. Published online 2018 Nov 20. doi: 10.1038/sdata.2018.262

PMCID:: PMC6244183

Abstract Article PDF–753K

Select item 611541713.

Argininosuccinic aciduria fosters neuronal nitrosative stress reversed by Asl gene transfer

Julien Baruteau, Dany P. Perocheau, Joanna Hanley, Maëlle Lorvellec, Eridan Rocha-Ferreira, Rajvinder Karda, Joanne Ng, Natalie Suff, Juan Antinao Diaz, Ahad A. Rahim, Michael P. Hughes, Blerida Banushi, Helen Prunty, Mariya Hristova, Deborah A. Ridout, Alex Virasami, Simon Heales, Stewen J. Howe, Suzanne M. K. Buckley, Philippa B. Mills, Paul Gissen, Simon N. Waddington

Nat Commun. 2018; 9: 3505. Published online 2018 Aug 29. doi: 10.1038/s41467-018-05972-1

PMCID:: PMC6115417

Abstract Article PDF–2.2M

Select item 608083314.

Argininosuccinate Lyase Deficiency Causes an Endothelial-Dependent Form of Hypertension

Jordan Kho, Xiaoyu Tian, Wing-Tak Wong, Terry Bertin, Ming-Ming Jiang, Shan Chen, Zixue Jin, Oleg A. Shchelochkov, Lindsay C. Burrage, Anilkumar K. Reddy, Hong Jiang, Reem Abo-Zahrah, Shuangtao Ma, Ping Zhang, Karl-Dimiter Bissig, Jean J. Kim, Sridevi Devaraj, George G. Rodney, Ayelet Erez, Nathan S. Bryan, Sandesh C.S. Nagamani, Brendan H. Lee

Am J Hum Genet. 2018 Aug 2; 103(2): 276–287. Published online 2018 Aug 2. doi: 10.1016/j.ajhg.2018.07.008

PMCID:: PMC6080833

Abstract Article PDF–1.9M

Select item 597657715.

Induction of Nitric-Oxide Metabolism in Enterocytes Alleviates Colitis and Inflammation-Associated Colon Cancer

Noa Stettner, Chava Rosen, Biana Bernshtein, Shiri Gur-Cohen, Julia Frug, Alon Silberman, Alona Sarver, Narin N. Carmel-Neiderman, Raya Eilam, Inbal Biton, Meirav Pevsner-Fischer, Niv Zmora, Alexander Brandis, Keren Bahar Halpern, Ram Mazkereth, Diego di Bernardo, Nicola Brunetti-Pierri, Muralidhar H. Premkumar, Gillian Dank, Sandesh C.S. Nagamani, Steffen Jung, Alon Harmelin, Ayelet Erez

Cell Rep. 2018 May 15; 23(7): 1962–1976. Published online 2018 May 15. doi: 10.1016/j.celrep.2018.04.053

PMCID:: PMC5976577

Abstract Article

Select item 412164016.

Argininosuccinate lyase in enterocytes protects from development of necrotizing enterocolitis

M. H. Premkumar, G. Sule, S. C. Nagamani, S. Chakkalakal, A. Nordin, M. Jain, M. Z. Ruan, T. Bertin, B. Dawson, J. Zhang, D. Schady, N. S. Bryan, P. M. Campeau, A. Erez, B. Lee

Am J Physiol Gastrointest Liver Physiol. 2014 Aug 1; 307(3): G347–G354. Published online 2014 Jun 5. doi: 10.1152/ajpgi.00403.2013

PMCID:: PMC4121640

Abstract Article

Select item 337649117.

Nitric-Oxide Supplementation for Treatment of Long-Term Complications in Argininosuccinic Aciduria

Sandesh C.S. Nagamani, Philippe M. Campeau, Oleg A. Shchelochkov, Muralidhar H. Premkumar, Kilian Guse, Nicola Brunetti-Pierri, Yuqing Chen, Qin Sun, Yaoping Tang, Donna Palmer, Anilkumar K. Reddy, Li Li, Timothy C. Slesnick, Daniel I. Feig, Susan Caudle, David Harrison, Leonardo Salviati, Juan C. Marini, Nathan S. Bryan, Ayelet Erez, Brendan Lee

Am J Hum Genet. 2012 May 4; 90(5): 836–846. doi: 10.1016/j.ajhg.2012.03.018

PMCID:: PMC3376491

Abstract Article PDF–588K

Select item 334895618.

REQUIREMENT OF ARGININOSUCCINATE LYASE FOR SYSTEMIC NITRIC OXIDE PRODUCTION

Ayelet Erez, Sandesh CS. Nagamani, Oleg A. Shchelochkov, Muralidhar H. Premkumar, Philippe M. Campeau, Yuqing Chen, Harsha K. Garg, Li Li, Asad Mian, Terry K. Bertin, Jennifer O. Black, Heng Zeng, Yaoping Tang, Anilkumar K. Reddy, Marshall Summar, William E. O’Brien, David G. Harrison, William E. Mitch, Juan C. Marini, Judy L. Aschner, Nathan S. Bryan, Brendan Lee

Nat Med. Author manuscript; available in PMC 2012 Dec 1.

Published in final edited form as: Nat Med. 2011 Nov 13; 17(12): 1619–1626. Published online 2011 Nov 13. doi: 10.1038/nm.2544

PMCID:: PMC3348956

Abstract Article PDF–3.9M

Select item 332215719.

Short-Chain 3-Hydroxyacyl-Coenzyme A Dehydrogenase Associates with a Protein Super-Complex Integrating Multiple Metabolic Pathways

Srinivas B. Narayan, Stephen R. Master, Anthony N. Sireci, Charlene Bierl, Paige E. Stanley, Changhong Li, Charles A. Stanley, Michael J. Bennett

PLoS One. 2012; 7(4): e35048. Published online 2012 Apr 9. doi: 10.1371/journal.pone.0035048

PMCID:: PMC3322157

Abstract Article PDF–219K

Select item 317805920.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

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