PMC Links for GEO Profiles (Select 115290907) - PMC

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 108252774.

Cerebral furin deficiency causes hydrocephalus in mice

Shiqi Xie, Xiaoyong Xie, Jing Tang, Biao Luo, Jian Chen, Qixin Wen, Jianrong Zhou, Guojun Chen

Genes Dis. 2024 May; 11(3): 101009. Published online 2023 Jul 8. doi: 10.1016/j.gendis.2023.04.037

PMCID:: PMC10825277

Abstract Article PDF–4.6M

Select item 106693615.

Furin Regulates the Alveolarization of Neonatal Lungs in a Mouse Model of Hyperoxic Lung Injury

Shin Kato, Osuke Iwata, Hiroyuki Kato, Satoko Fukaya, Yukari Imai, Shinji Saitoh

Biomolecules. 2023 Nov; 13(11): 1656. Published online 2023 Nov 16. doi: 10.3390/biom13111656

PMCID:: PMC10669361

Abstract Article PDF–3.0M

Select item 96644686.

Loss of hypothalamic Furin affects POMC to proACTH cleavage and feeding behavior in high-fat diet-fed mice

Ilaria Coppola, Bas Brouwers, Leanne Walker, Ceyhun Alar, Sandra Meulemans, Anne White, Bruno Ramos-Molina, John W.M. Creemers

Mol Metab. 2022 Dec; 66: 101627. Published online 2022 Oct 29. doi: 10.1016/j.molmet.2022.101627

PMCID:: PMC9664468

Abstract Article PDF–1.4M

Select item 95992667.

Neuropilin-1 Facilitates Pseudorabies Virus Replication and Viral Glycoprotein B Promotes Its Degradation in a Furin-Dependent Manner

Meng Chen, Meng-Hang Wang, Xue-Gang Shen, Hao Liu, Yu-Yuan Zhang, Jin-Mei Peng, Fandan Meng, Tong-Yun Wang, Yuan-Zhe Bai, Ming-Xia Sun, Zhi-Jun Tian, Xin Yin, Xue-Hui Cai, Yan-Dong Tang

J Virol. 2022 Oct; 96(20): e01318-22. Published online 2022 Sep 29. doi: 10.1128/jvi.01318-22

PMCID:: PMC9599266

Abstract Article PDF–3.3M

Select item 95794868.

The proprotein convertase furin regulates the development of thymic epithelial cells to ensure central immune tolerance

Zhanfeng Liang, Zhaoqi Zhang, Qian Zhang, Xue Dong, Xiaofeng Yang, Jiayu Zhang, Tong Lei, John W.M. Creemers, Baojun Zhang, Yong Zhao

iScience. 2022 Oct 21; 25(10): 105233. Published online 2022 Sep 28. doi: 10.1016/j.isci.2022.105233

PMCID:: PMC9579486

Abstract Article PDF–5.8M

Select item 82319399.

Differential Effects of Furin Deficiency on Insulin Receptor Processing and Glucose Control in Liver and Pancreatic β Cells of Mice

Ilaria Coppola, Bas Brouwers, Sandra Meulemans, Bruno Ramos-Molina, John W. M. Creemers

Int J Mol Sci. 2021 Jun; 22(12): 6344. Published online 2021 Jun 14. doi: 10.3390/ijms22126344

PMCID:: PMC8231939

Abstract Article PDF–2.0M

Select item 821340310.

In Vivo Analysis of the Contribution of Proprotein Convertases to the Processing of FGF23

Omar Al Rifai, Delia Susan-Resiga, Rachid Essalmani, John W. M. Creemers, Nabil G. Seidah, Mathieu Ferron

Front Endocrinol (Lausanne) 2021; 12: 690681. Published online 2021 Jun 4. doi: 10.3389/fendo.2021.690681

PMCID:: PMC8213403

Abstract Article PDF–6.4M

Select item 793877011.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 793061912.

Identification of Novel Genetic Regulatory Region for Proprotein Convertase FURIN and Interferon Gamma in T Cells

Zsuzsanna Ortutay, Anna Grönholm, Melina Laitinen, Melinda Keresztes-Andrei, Ismail Hermelo, Marko Pesu

Front Immunol. 2021; 12: 630389. Published online 2021 Feb 18. doi: 10.3389/fimmu.2021.630389

PMCID:: PMC7930619

Abstract Article PDF–2.1M

Select item 782259213.

The half-life of the bone-derived hormone osteocalcin is regulated through O-glycosylation in mice, but not in humans

Omar Al Rifai, Catherine Julien, Julie Lacombe, Denis Faubert, Erandi Lira-Navarrete, Yoshiki Narimatsu, Henrik Clausen, Mathieu Ferron

eLife. 2020; 9: e61174. Published online 2020 Dec 7. doi: 10.7554/eLife.61174

PMCID:: PMC7822592

Abstract Article PDF–2.6M

Select item 640270114.

Furin, a transcriptional target of NKX2-5, has an essential role in heart development and function

Laurent Dupays, Norma Towers, Sophie Wood, Anna David, Daniel J. Stuckey, Timothy Mohun

PLoS One. 2019; 14(3): e0212992. Published online 2019 Mar 6. doi: 10.1371/journal.pone.0212992

PMCID:: PMC6402701

Abstract Article PDF–4.3M

Select item 639319315.

FURIN inhibition reduces vascular remodeling and atherosclerotic lesion progression in mice

Gopala K. Yakala, Hector A. Cabrera-Fuentes, Gustavo E. Crespo-Avilan, Chutima Rattanasopa, Alexandrina Burlacu, Benjamin L. George, Kaviya Anand, David Castano Mayan, Maria Corliano, Sauri Hernández-Reséndiz, Zihao Wu, Anne M.K. Schwerk, Amberlyn L.J. Tan, Laia Trigueros-Motos, Raphael Chevre, Tricia Chua, Robert Kleemann, Elisa A. Liehn, Derek J. Hausenloy, Sujoy Ghosh, Roshni R. Singaraja

Arterioscler Thromb Vasc Biol. Author manuscript; available in PMC 2020 Mar 1.

Published in final edited form as: Arterioscler Thromb Vasc Biol. 2019 Mar; 39(3): 387–401. doi: 10.1161/ATVBAHA.118.311903

PMCID:: PMC6393193

Abstract Article PDF–2.8M

Select item 629804016.

Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors

Hyeonwoo Kim, Christiane D. Wrann, Mark Jedrychowski, Sara Vidoni, Yukiko Kitase, Kenichi Nagano, Chenhe Zhou, Joshua Chou, Virginia-Jeni A. Parkman, Scott J. Novick, Timothy S. Strutzenberg, Bruce D. Pascal, Phuong T. Le, Daniel J. Brooks, Alexander M. Roche, Kaitlyn K. Gerber, Laura Mattheis, Wenjing Chen, Hua Tu, Mary L. Bouxsein, Patrick R. Griffin, Roland Baron, Clifford J. Rosen, Lynda F. Bonewald, Bruce M. Spiegelman

Cell. Author manuscript; available in PMC 2019 Dec 13.

Published in final edited form as: Cell. 2018 Dec 13; 175(7): 1756–1768.e17. doi: 10.1016/j.cell.2018.10.025

Correction in:: Cell. 2019 Jul 11; 178(2): 507–508.

PMCID:: PMC6298040

Abstract Article PDF–1.2M

Select item 620063117.

STAT6 and Furin Are Successive Triggers for the Production of TGFβ by T Cells

Yue Li, Weiren Liu, Xiaqun Guan, Jamie Truscott, John W. Creemers, Hung-Lin Chen, Marko Pesu, Rami G. El Abiad, Bahri Karacay, Joseph F. Urban, Jr, David E. Elliott, Mark H. Kaplan, Bruce R. Blazar, M. Nedim Ince

J Immunol. Author manuscript; available in PMC 2019 Nov 1.

Published in final edited form as: J Immunol. 2018 Nov 1; 201(9): 2612–2623. Published online 2018 Sep 28. doi: 10.4049/jimmunol.1700808

PMCID:: PMC6200631

Abstract Article PDF–2.1M

Select item 609211218.

Influence of a Coronary Artery Disease–Associated Genetic Variant on FURIN Expression and Effect of Furin on Macrophage Behavior

Guojun Zhao, Wei Yang, Jingchun Wu, Bairu Chen, Xu Yang, Junhui Chen, David G. McVey, Catherine Andreadi, Peng Gong, Tom R. Webb, Nilesh J. Samani, Shu Ye

Arterioscler Thromb Vasc Biol. 2018 Aug; 38(8): 1837–1844. Published online 2018 Jul 5. doi: 10.1161/ATVBAHA.118.311030

PMCID:: PMC6092112

Abstract Article PDF–1.0M

Select item 581121619.

Cleavage activates Dispatched for Sonic Hedgehog ligand release

Daniel P Stewart, Suresh Marada, William J Bodeen, Ashley Truong, Sadie Miki Sakurada, Tanushree Pandit, Shondra M Pruett-Miller, Stacey K Ogden

eLife. 2018; 7: e31678. Published online 2018 Jan 23. doi: 10.7554/eLife.31678

PMCID:: PMC5811216

Abstract Article PDF–2.8M

Select item 566335020.

Proprotein convertase furin regulates osteocalcin and bone endocrine function

Omar Al Rifai, Jacqueline Chow, Julie Lacombe, Catherine Julien, Denis Faubert, Delia Susan-Resiga, Rachid Essalmani, John W.M. Creemers, Nabil G. Seidah, Mathieu Ferron

J Clin Invest. 2017 Nov 1; 127(11): 4104–4117. Published online 2017 Oct 3. doi: 10.1172/JCI93437

PMCID:: PMC5663350

Abstract Article PDF–5.4M

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