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Items: 1 to 20 of 2029

1.
Nanoparticle-based itaconate treatment recapitulates low-cholesterol/low-fat diet-induced atherosclerotic plaque resolution
Natalie E. Hong, Alice Chaplin, Lin Di, Anastasia Ravodina, Graham H. Bevan, Huiyun Gao, Courteney Asase, Roopesh Singh Gangwar, Mark J. Cameron, Matthew Mignery, Olga Cherepanova, Aloke V. Finn, Lalitha Nayak, Andrew A. Pieper, Andrei Maiseyeu
Cell Rep. Author manuscript; available in PMC 2024 Dec 16.
Published in final edited form as: Cell Rep. 2024 Nov 26; 43(11): 114911. Published online 2024 Oct 28. doi: 10.1016/j.celrep.2024.114911
PMCID:
PMC11648168
AbstractArticlePDF–4.8M
2.
Activation of receptor-independent fluid-phase pinocytosis promotes foamy monocyte formation in atherosclerotic mice
WonMo Ahn, Faith N. Burnett, Kamila Wojnar-Lason, Jaser Doja, Amritha Sreekumar, Pushpankur Ghoshal, Bhupesh Singla, Graydon Gonsalvez, Ryan A. Harris, Xiaoling Wang, Joseph M. Miano, Gábor Csányi
Redox Biol. 2024 Dec; 78: 103423. Published online 2024 Nov 6. doi: 10.1016/j.redox.2024.103423
PMCID:
PMC11647241
AbstractArticlePDF–13M
3.
Latexin deficiency limits foam cell formation and ameliorates atherosclerosis by promoting macrophage phenotype differentiation
Guozhang He, Yuanting Ni, Rong Hua, Huaibin Wan, Yanhui Tan, Qiwei Chen, Shaohua Xu, Yuzhong Yang, Lijun Zhang, Wei Shu, Ke-Bin Huang, Yi Mo, Hong Liang, Ming Chen
Cell Death Dis. 2024 Oct; 15(10): 754. Published online 2024 Oct 18. doi: 10.1038/s41419-024-07141-3
PMCID:
PMC11492231
AbstractArticlePDF–5.1M
4.
Aberrant mitochondrial DNA synthesis in macrophages exacerbates inflammation and atherosclerosis
Niranjana Natarajan, Jonathan Florentin, Ebin Johny, Hanxi Xiao, Scott Patrick O’Neil, Liqun Lei, Jixing Shen, Lee Ohayon, Aaron R. Johnson, Krithika Rao, Xiaoyun Li, Yanwu Zhao, Yingze Zhang, Sina Tavakoli, Sruti Shiva, Jishnu Das, Partha Dutta
Nat Commun. 2024; 15: 7337. Published online 2024 Aug 26. doi: 10.1038/s41467-024-51780-1
PMCID:
PMC11347661
AbstractArticlePDF–4.7M
5.
Apolipoprotein E knockout, but not cholesteryl ester transfer protein (CETP)-associated high-density lipoprotein cholesterol (HDL-C) lowering, exacerbates muscle wasting in dysferlin-null mice
Zeren Sun, Zoe White, Marine Theret, Pascal Bernatchez
Lipids Health Dis. 2024; 23: 247. Published online 2024 Aug 13. doi: 10.1186/s12944-024-02227-5
PMCID:
PMC11321019
AbstractArticlePDF–6.3M
6.
Effects of a high-fat diet on cognition and brain distribution of intranasal insulin in E3 and E4 male and female mice
Ariel Chaklai, Elizabeth M. Rhea, Abigail O’Niel, Alice Babin, Riley Weaver, Sarah Pemberton, William A. Banks, Jacob Raber
Sci Rep. 2024; 14: 18641. Published online 2024 Aug 11. doi: 10.1038/s41598-024-62053-8
PMCID:
PMC11317510
AbstractArticlePDF–6.9M
7.
Lack of alpha CGRP exacerbates the development of atherosclerosis in ApoE-knockout mice
Narumi Hashikawa-Hobara, Shota Inoue, Naoya Hashikawa
Sci Rep. 2024; 14: 18377. Published online 2024 Aug 8. doi: 10.1038/s41598-024-69331-5
PMCID:
PMC11306347
AbstractArticlePDF–1.7M
8.
The chemotherapeutic agent doxorubicin induces brain senescence, with modulation by APOE genotype
Tamar Demby, Phillip S. Gross, Jeanne Mandelblatt, Jeffrey K. Huang, G. William Rebeck
Exp Neurol. Author manuscript; available in PMC 2024 Aug 6.
Published in final edited form as: Exp Neurol. 2024 Jan; 371: 114609. Published online 2023 Nov 7. doi: 10.1016/j.expneurol.2023.114609
PMCID:
PMC11302516
AbstractArticlePDF–1.0M
9.
Altering heparan sulfate suppresses cell abnormalities and neuron loss in Drosophila presenilin model of Alzheimer Disease
Nicholas Schultheis, Alyssa Connell, Alexander Kapral, Robert J. Becker, Richard Mueller, Shalini Shah, Mackenzie O'Donnell, Matthew Roseman, Lindsey Swanson, Sophia DeGuara, Weihua Wang, Fei Yin, Tripti Saini, Ryan J. Weiss, Scott B. Selleck
iScience. 2024 Jul 19; 27(7): 110256. Published online 2024 Jul 2. doi: 10.1016/j.isci.2024.110256
PMCID:
PMC11302002
AbstractArticlePDF–6.0M
10.
In vivo validation of late‐onset Alzheimer's disease genetic risk factors
Michael Sasner, Christoph Preuss, Ravi S. Pandey, Asli Uyar, Dylan Garceau, Kevin P. Kotredes, Harriet Williams, Adrian L. Oblak, Peter Bor‐Chian Lin, Bridget Perkins, Disha Soni, Cindy Ingraham, Audrey Lee‐Gosselin, Bruce T. Lamb, Gareth R. Howell, Gregory W. Carter
Alzheimers Dement. 2024 Jul; 20(7): 4970–4984. Published online 2024 Apr 30. doi: 10.1002/alz.13840
PMCID:
PMC11247676
AbstractArticlePDF–3.3M
11.
Assessment of neurovascular uncoupling: APOE status is a key driver of early metabolic and vascular dysfunction
Kristen D. Onos, Peter B. Lin, Ravi S. Pandey, Scott A. Persohn, Charles P. Burton, Ethan W. Miner, Kierra Eldridge, Jonathan Nyandu Kanyinda, Kate E. Foley, Gregory W. Carter, Gareth R. Howell, Paul R. Territo
Alzheimers Dement. 2024 Jul; 20(7): 4951–4969. Published online 2024 May 7. doi: 10.1002/alz.13842
PMCID:
PMC11247674
AbstractArticlePDF–14M
12.
Activation of Nrf2 inhibits atherosclerosis in ApoE−/− mice through suppressing endothelial cell inflammation and lipid peroxidation
Lei He, Qinghua Chen, Li Wang, Yujie Pu, Juan Huang, Chak Kwong Cheng, Jiang-Yun Luo, Lijing Kang, Xiao Lin, Li Xiang, Liang Fang, Ben He, Yin Xia, Kathy O. Lui, Yong Pan, Jie Liu, Cheng-Lin Zhang, Yu Huang
Redox Biol. 2024 Aug; 74: 103229. Published online 2024 Jun 6. doi: 10.1016/j.redox.2024.103229
PMCID:
PMC11247299
AbstractArticlePDF–18M
13.
Apolipoprotein E polymorphisms and female fertility in a transgenic mouse model of Alzheimer’s disease
Bani Medegan Fagla, Jason York, Amy Christensen, Cielo Dela Rosa, Deebika Balu, Christian J. Pike, Leon M. Tai, Irina A. Buhimschi
Sci Rep. 2024; 14: 15873. Published online 2024 Jul 10. doi: 10.1038/s41598-024-66489-w
PMCID:
PMC11233746
AbstractArticlePDF–3.3M
14.
Endothelial Dickkopf-1 Promotes Smooth Muscle Cell-derived Foam Cell Formation via USP53-mediated Deubiquitination of SR-A During Atherosclerosis
Xiaolin Liu, Tengfei Zheng, Yu Zhang, Yachao Zhao, Fengming Liu, Shen Dai, Meng Zhang, Wencheng Zhang, Cheng Zhang, Mei Zhang, Xiao Li
Int J Biol Sci. 2024; 20(8): 2943–2964. Published online 2024 May 19. doi: 10.7150/ijbs.91957
PMCID:
PMC11186357
AbstractArticlePDF–15M
15.
Metabolomics profiling reveals distinct, sex‐specific signatures in serum and brain metabolomes in mouse models of Alzheimer's disease
Ravi S. Pandey, Mattias Arnold, Richa Batra, Jan Krumsiek, Kevin P. Kotredes, Dylan Garceau, Harriet Williams, Michael Sasner, Gareth R. Howell, Rima Kaddurah‐Daouk, Gregory W. Carter
Alzheimers Dement. 2024 Jun; 20(6): 3987–4001. Published online 2024 Apr 27. doi: 10.1002/alz.13851
PMCID:
PMC11180854
AbstractArticlePDF–1.5M
16.
Characterizing molecular and synaptic signatures in mouse models of late‐onset Alzheimer's disease independent of amyloid and tau pathology
Kevin P. Kotredes, Ravi S. Pandey, Scott Persohn, Kierra Elderidge, Charles P Burton, Ethan W. Miner, Kathryn A. Haynes, Diogo Francisco S. Santos, Sean‐Paul Williams, Nicholas Heaton, Cynthia M. Ingraham, Christopher Lloyd, Dylan Garceau, Rita O'Rourke, Sarah Herrick, Claudia Rangel‐Barajas, Surendra Maharjan, Nian Wang, Michael Sasner, Bruce T. Lamb, Paul R. Territo, Stacey J. Sukoff Rizzo, Gregory W. Carter, Gareth R. Howell, Adrian L. Oblak
Alzheimers Dement. 2024 Jun; 20(6): 4126–4146. Published online 2024 May 12. doi: 10.1002/alz.13828
PMCID:
PMC11180851
AbstractArticlePDF–7.5M
17.
Resolving neutrophils through genetic deletion of TRAM attenuate atherosclerosis pathogenesis
Shuo Geng, Yao Zhang, Ran Lu, Daniel Irimia, Liwu Li
iScience. 2024 Jun 21; 27(6): 110097. Published online 2024 May 24. doi: 10.1016/j.isci.2024.110097
PMCID:
PMC11179630
AbstractArticlePDF–4.8M
18.
Pharmacological Inhibition of MMP-12 Exerts Protective Effects on Angiotensin II-Induced Abdominal Aortic Aneurysms in Apolipoprotein E-Deficient Mice
Karina Di Gregoli, Georgia Atkinson, Helen Williams, Sarah J. George, Jason L. Johnson
Int J Mol Sci. 2024 Jun; 25(11): 5809. Published online 2024 May 27. doi: 10.3390/ijms25115809
PMCID:
PMC11172660
AbstractArticlePDF–4.6M
19.
WISP-1 Regulates Cardiac Fibrosis by Promoting Cardiac Fibroblasts’ Activation and Collagen Processing
Ze Li, Helen Williams, Molly L. Jackson, Jason L. Johnson, Sarah J. George
Cells. 2024 Jun; 13(11): 989. Published online 2024 Jun 6. doi: 10.3390/cells13110989
PMCID:
PMC11172092
AbstractArticlePDF–6.8M
20.
APOE2 protects against Aβ pathology by improving neuronal mitochondrial function through ERRα signaling
Zhiyuan Ning, Ying Liu, Mengyao Wan, You Zuo, Siqi Chen, Zhongshan Shi, Yongteng Xu, Honghong Li, Ho Ko, Jing Zhang, Songhua Xiao, Daji Guo, Yamei Tang
Cell Mol Biol Lett. 2024; 29: 87. Published online 2024 Jun 12. doi: 10.1186/s11658-024-00600-x
PMCID:
PMC11170814
AbstractArticlePDF–4.1M

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