U.S. flag

An official website of the United States government

Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Links from GEO Profiles

Items: 1 to 20 of 93

1.
Truncated Dyrk1A aggravates neuronal apoptosis by inhibiting ASF‐mediated Bcl‐x exon 2b inclusion
Shuqiang Zhang, Junjie Zhong, Lian Xu, Yue Wu, Jie Xu, Jianhua Shi, Zhikai Gu, Xiaoyu Li, Nana Jin
CNS Neurosci Ther. 2024 Apr; 30(4): e14493. Published online 2023 Oct 21. doi: 10.1111/cns.14493
PMCID:
PMC11017436
AbstractArticlePDF–12M
2.
An in vitro neurogenetics platform for precision disease modeling in the mouse
Daniel E. Cortes, Mélanie Escudero, Austin C. Korgan, Arojit Mitra, Alyssa Edwards, Selcan C. Aydin, Steven C. Munger, Kevin Charland, Zhong-Wei Zhang, Kristen M. S. O'Connell, Laura G. Reinholdt, Martin F. Pera
Sci Adv. 2024 Apr 5; 10(14): eadj9305. Published online 2024 Apr 3. doi: 10.1126/sciadv.adj9305
PMCID:
PMC10990289
AbstractArticlePDF–7.4M
3.
MicroRNA-221-3p inhibits the inflammatory response of keratinocytes by regulating the DYRK1A/STAT3 signaling pathway to promote wound healing in diabetes
Keyan Hu, Lei Liu, Songtao Tang, Xin Zhang, Hongfeng Chang, Wenyang Chen, Taotao Fan, Lesha Zhang, Bing Shen, Qiu Zhang
Commun Biol. 2024; 7: 300. Published online 2024 Mar 9. doi: 10.1038/s42003-024-05986-0
PMCID:
PMC10924844
AbstractArticlePDF–18M
4.
Sex-specific developmental alterations in DYRK1A expression in the brain of a Down syndrome mouse model
Laura E. Hawley, Megan Stringer, Abigail J. Deal, Andrew Folz, Charles R. Goodlett, Randall J. Roper
Neurobiol Dis. Author manuscript; available in PMC 2024 Feb 5.
Published in final edited form as: Neurobiol Dis. 2024 Jan; 190: 106359. Published online 2023 Nov 20. doi: 10.1016/j.nbd.2023.106359
PMCID:
PMC10843801
AbstractArticlePDF–1.2M
5.
Deficits in neuronal architecture but not over-inhibition are main determinants of reduced neuronal network activity in a mouse model of overexpression of Dyrk1A
Linus Manubens-Gil, Meritxell Pons-Espinal, Thomas Gener, Inmaculada Ballesteros-Yañez, María Martínez de Lagrán, Mara Dierssen
Cereb Cortex. 2024 Jan; 34(1): bhad431. Published online 2023 Nov 23. doi: 10.1093/cercor/bhad431
PMCID:
PMC10793573
AbstractArticlePDF–4.2M
6.
Haploid-genetic screening of trophectoderm specification identifies Dyrk1a as a repressor of totipotent-like status
Wenhao Zhang, Shengyi Sun, Qing Wang, Xu Li, Mei Xu, Qian Li, Yiding Zhao, Keli Peng, Chunmeng Yao, Yuna Wang, Ying Chang, Yan Liu, Xudong Wu, Qian Gao, Ling Shuai
Sci Adv. 2023 Dec 22; 9(51): eadi5683. Published online 2023 Dec 20. doi: 10.1126/sciadv.adi5683
PMCID:
PMC10732524
AbstractArticlePDF–1.6M
7.
An inhibitory circuit-based enhancer of DYRK1A function reverses Dyrk1a-associated impairment in social recognition
Yu-Tzu Shih, Jason Bondoc Alipio, Amar Sahay
Neuron. Author manuscript; available in PMC 2024 Oct 4.
Published in final edited form as: Neuron. 2023 Oct 4; 111(19): 3084–3101.e5. doi: 10.1016/j.neuron.2023.09.009
PMCID:
PMC10575685
AbstractArticlePDF–2.8M
8.
Over‐expression of Dyrk1A affects bleeding by modulating plasma fibronectin and fibrinogen level in mice
Guillaume Postic, Jean Solarz, Cécile Loubière, Janany Kandiah, Jaysen Sawmynaden, Frederic Adam, Marie Vilaire, Thibaut Léger, Jean‐Michel Camadro, Daniella Balduino Victorino, Marie‐Claude Potier, Eric Bun, Gautier Moroy, Alexandre Kauskot, Olivier Christophe, Nathalie Janel
J Cell Mol Med. 2023 Aug; 27(15): 2228–2238. Published online 2023 Jul 6. doi: 10.1111/jcmm.17817
PMCID:
PMC10399536
AbstractArticlePDF–1.3M
9.
KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility
Juan Gu, Pingyang Ke, Haokun Guo, Jing Liu, Yan Liu, Xin Tian, Zhuo Huang, Xin Xu, Demei Xu, Yuanlin Ma, Xuefeng Wang, Fei Xiao
Cell Death Differ. 2023 Jul; 30(7): 1726–1741. Published online 2023 May 4. doi: 10.1038/s41418-023-01174-5
PMCID:
PMC10307852
AbstractArticlePDF–8.8M
10.
DYRK1A promotes viral entry of highly pathogenic human coronaviruses in a kinase-independent manner
Madison S. Strine, Wesley L. Cai, Jin Wei, Mia Madel Alfajaro, Renata B. Filler, Scott B. Biering, Sylvia Sarnik, Ryan D. Chow, Ajinkya Patil, Kasey S. Cervantes, Clayton K. Collings, Peter C. DeWeirdt, Ruth E. Hanna, Kevin Schofield, Christopher Hulme, Silvana Konermann, John G. Doench, Patrick D. Hsu, Cigall Kadoch, Qin Yan, Craig B. Wilen
PLoS Biol. 2023 Jun; 21(6): e3002097. Published online 2023 Jun 13. doi: 10.1371/journal.pbio.3002097
PMCID:
PMC10263356
AbstractArticlePDF–2.6M
11.
Craniofacial dysmorphology in Down syndrome is caused by increased dosage of Dyrk1a and at least three other genes
Yushi Redhead, Dorota Gibbins, Eva Lana-Elola, Sheona Watson-Scales, Lisa Dobson, Matthias Krause, Karen J. Liu, Elizabeth M. C. Fisher, Jeremy B. A. Green, Victor L. J. Tybulewicz
Development. 2023 Apr 15; 150(8): dev201077. Published online 2023 Apr 26. doi: 10.1242/dev.201077
PMCID:
PMC10163349
AbstractArticle
12.
Large-Scale Functional Assessment of Genes Involved in Rare Diseases with Intellectual Disabilities Unravels Unique Developmental and Behaviour Profiles in Mouse Models
Hamid Meziane, Marie-Christine Birling, Olivia Wendling, Sophie Leblanc, Aline Dubos, Mohammed Selloum, Guillaume Pavlovic, Tania Sorg, Vera M. Kalscheuer, Pierre Billuart, Frédéric Laumonnier, Jamel Chelly, Hans van Bokhoven, Yann Herault
Biomedicines. 2022 Dec; 10(12): 3148. Published online 2022 Dec 6. doi: 10.3390/biomedicines10123148
PMCID:
PMC9775489
AbstractArticlePDF–2.8M
13.
Impaired macroglial development and axonal conductivity contributes to the neuropathology of DYRK1A-related intellectual disability syndrome
Isabel Pijuan, Elisa Balducci, Cristina Soto-Sánchez, Eduardo Fernández, María José Barallobre, Maria L. Arbonés
Sci Rep. 2022; 12: 19912. Published online 2022 Nov 19. doi: 10.1038/s41598-022-24284-5
PMCID:
PMC9675854
AbstractArticlePDF–4.8M
14.
Relieving DYRK1A repression of MKL1 confers an adult-like phenotype to human infantile megakaryocytes
Kamaleldin E. Elagib, Ashton Brock, Cara M. Clementelli, Goar Mosoyan, Lorrie L. Delehanty, Ranjit K. Sahu, Alexandra Pacheco-Benichou, Corinne Fruit, Thierry Besson, Stephan W. Morris, Koji Eto, Chintan Jobaliya, Deborah L. French, Paul Gadue, Sandeep Singh, Xinrui Shi, Fujun Qin, Robert Cornelison, Hui Li, Camelia Iancu-Rubin, Adam N. Goldfarb
J Clin Invest. 2022 Oct 3; 132(19): e154839. Published online 2022 Oct 3. doi: 10.1172/JCI154839
PMCID:
PMC9525118
AbstractArticlePDF–7.2M
15.
Chr21 protein–protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer’s disease
Julia Viard, Yann Loe-Mie, Rachel Daudin, Malik Khelfaoui, Christine Plancon, Anne Boland, Francisco Tejedor, Richard L Huganir, Eunjoon Kim, Makoto Kinoshita, Guofa Liu, Volker Haucke, Thomas Moncion, Eugene Yu, Valérie Hindie, Henri Bléhaut, Clotilde Mircher, Yann Herault, Jean-François Deleuze, Jean-Christophe Rain, Michel Simonneau, Aude-Marie Lepagnol-Bestel
Life Sci Alliance. 2022 Dec; 5(12): e202101205. Published online 2022 Aug 1. doi: 10.26508/lsa.202101205
PMCID:
PMC9348576
AbstractArticlePDF–3.0M
16.
Inhibition of DYRK1A, via histone modification, promotes cardiomyocyte cell cycle activation and cardiac repair after myocardial infarction
Cong Lan, Caiyu Chen, Shuang Qu, Nian Cao, Hao Luo, Cheng Yu, Na Wang, Yuanzheng Xue, Xuewei Xia, Chao Fan, Hongmei Ren, Yongjian Yang, Pedro A. Jose, Zaicheng Xu, Gengze Wu, Chunyu Zeng
eBioMedicine. 2022 Aug; 82: 104139. Published online 2022 Jul 8. doi: 10.1016/j.ebiom.2022.104139
PMCID:
PMC9278077
AbstractArticlePDF–4.8M
17.
DYRK1a mediates BAFF-induced noncanonical NF-κB activation to promote autoimmunity and B-cell leukemogenesis
Yanchuan Li, Xiaoping Xie, Zuliang Jie, Lele Zhu, Jin-Young Yang, Chun-Jung Ko, Tianxiao Gao, Antrix Jain, Sung Yun Jung, Natalia Baran, Marina Y. Konopleva, Xuhong Cheng, Shao-Cong Sun
Blood. 2021 Dec 9; 138(23): 2360–2371. doi: 10.1182/blood.2021011247
PMCID:
PMC8832461
AbstractArticle
18.
Dyrk1a mutations cause undergrowth of cortical pyramidal neurons via dysregulated growth factor signaling
Jenna A. Levy, Christy W. LaFlamme, George Tsaprailis, Gogce Crynen, Damon T. Page
Biol Psychiatry. Author manuscript; available in PMC 2022 Sep 1.
Published in final edited form as: Biol Psychiatry. 2021 Sep 1; 90(5): 295–306. Published online 2021 Apr 8. doi: 10.1016/j.biopsych.2021.01.012
PMCID:
PMC8787822
AbstractArticlePDF–3.0M
19.
The interactome of CLUH reveals its association to SPAG5 and its co-translational proximity to mitochondrial proteins
Mickaële Hémono, Alexandre Haller, Johana Chicher, Anne-Marie Duchêne, Richard Patryk Ngondo
BMC Biol. 2022; 20: 13. Published online 2022 Jan 10. doi: 10.1186/s12915-021-01213-y
PMCID:
PMC8744257
AbstractArticlePDF–6.0M
20.
Skeletal Deficits in Male and Female down Syndrome Model Mice Arise Independent of Normalized Dyrk1a Expression in Osteoblasts
Jared R. Thomas, Kourtney Sloan, Kelsey Cave, Joseph M. Wallace, Randall J. Roper
Genes (Basel) 2021 Nov; 12(11): 1729. Published online 2021 Oct 28. doi: 10.3390/genes12111729
PMCID:
PMC8624983
AbstractArticlePDF–2.7M

Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Supplemental Content

Filter your results:

Find related data

Recent activity

You are here: NCBI > Literature > PubMed Central (PMC)
Support Center