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Select item 109316051.

Deletion of Gadd45a Expression in Mice Leads to Cognitive and Synaptic Impairment Associated with Alzheimer’s Disease Hallmarks

Christian Griñán-Ferré, Júlia Jarne-Ferrer, Aina Bellver-Sanchis, Marta Ribalta-Vilella, Emma Barroso, Jesús M. Salvador, Javier Jurado-Aguilar, Xavier Palomer, Manuel Vázquez-Carrera, Mercè Pallàs

Int J Mol Sci. 2024 Mar; 25(5): 2595. Published online 2024 Feb 23. doi: 10.3390/ijms25052595

PMCID:: PMC10931605

Abstract Article PDF–3.7M

Select item 105614322.

GADD45A regulates subcutaneous fat deposition and lipid metabolism by interacting with Stat1

Wenjing You, Shiqi Liu, Jie Li, Yuang Tu, Tizhong Shan

BMC Biol. 2023; 21: 212. Published online 2023 Oct 9. doi: 10.1186/s12915-023-01713-z

PMCID:: PMC10561432

Abstract Article PDF–4.2M

Select item 105594523.

Impact of GADD45A on radiation biodosimetry using mouse peripheral blood

Constantinos G. Broustas, Sanjay Mukherjee, Igor Shuryak, Alexandra Taraboletti, Jerry Angdisen, Pelagie Ake, Albert J. Fornace, Jr., Sally A. Amundson

Radiat Res. Author manuscript; available in PMC 2023 Oct 7.

Published in final edited form as: Radiat Res. 2023 Sep 1; 200(3): 296–306. doi: 10.1667/RADE-23-00052.1

PMCID:: PMC10559452

Abstract Article PDF–768K

Select item 104787534.

Lem2 is essential for cardiac development by maintaining nuclear integrity

Jacob A Ross, Nathaly Arcos-Villacis, Edmund Battey, Cornelis Boogerd, Constanza Avalos Orellana, Emilie Marhuenda, Pamela Swiatlowska, Didier Hodzic, Fabrice Prin, Tim Mohun, Norman Catibog, Olga Tapia, Larry Gerace, Thomas Iskratsch, Ajay M Shah, Matthew J Stroud

Cardiovasc Res. 2023 Aug; 119(11): 2074–2088. Published online 2023 Apr 17. doi: 10.1093/cvr/cvad061

PMCID:: PMC10478753

Abstract Article PDF–33M

Select item 103790855.

GADD45A and GADD45B as Novel Biomarkers Associated with Chromatin Regulators in Renal Ischemia-Reperfusion Injury

Ming Xie, Ruiyan Xie, Pengcheng Huang, Desmond Y. H. Yap, Peng Wu

Int J Mol Sci. 2023 Jul; 24(14): 11304. Published online 2023 Jul 11. doi: 10.3390/ijms241411304

PMCID:: PMC10379085

Abstract Article PDF–11M

Select item 98919746.

Growth arrest and DNA damage‐inducible alpha regulates muscle repair and fat infiltration through ATP synthase F1 subunit alpha

Wenjing You, Shiqi Liu, Jianfei Ji, Defeng Ling, Yuang Tu, Yanbing Zhou, Wentao Chen, Teresa G. Valencak, Yizhen Wang, Tizhong Shan

J Cachexia Sarcopenia Muscle. 2023 Feb; 14(1): 326–341. Published online 2022 Dec 13. doi: 10.1002/jcsm.13134

PMCID:: PMC9891974

Abstract Article PDF–6.0M

Select item 98919407.

Loss of FoxOs in muscle increases strength and mitochondrial function during aging

Christie M. Penniman, Gourav Bhardwaj, Colette J. Nowers, Chandler U. Brown, Taylor L. Junck, Cierra K. Boyer, Jayashree Jena, Jordan D. Fuqua, Vitor A. Lira, Brian T. O'Neill

J Cachexia Sarcopenia Muscle. 2023 Feb; 14(1): 243–259. Published online 2022 Nov 28. doi: 10.1002/jcsm.13124

PMCID:: PMC9891940

Abstract Article PDF–4.8M

Select item 84100748.

GADD45A is a protective modifier of neurogenic skeletal muscle atrophy

Jeffrey T. Ehmsen, Riki Kawaguchi, Damlanur Kaval, Anna E. Johnson, Daniel Nachun, Giovanni Coppola, Ahmet Höke

JCI Insight. 2021 Jul 8; 6(13): e149381. Published online 2021 Jul 8. doi: 10.1172/jci.insight.149381

PMCID:: PMC8410074

Abstract Article PDF–14M

Select item 83132399.

Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development

Francesco Bedogni, Robert F. Hevner

Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034

PMCID:: PMC8313239

Abstract Article PDF–1.6M

Select item 802656310.

Robust p53 stabilization is dispensable for its activation and tumor suppressor function

Ning Kon, Michael Churchill, Huan Li, Siddhartha Mukherjee, James J. Manfredi, Wei Gu

Cancer Res. Author manuscript; available in PMC 2021 Aug 15.

Published in final edited form as: Cancer Res. 2021 Feb 15; 81(4): 935–944. Published online 2020 Dec 15. doi: 10.1158/0008-5472.CAN-20-1804

PMCID:: PMC8026563

Abstract Article PDF–1.5M

Select item 793589011.

Single cell transcriptomics reveals lineage trajectory of retinal ganglion cells in wild-type and Atoh7-null retinas

Fuguo Wu, Jonathan E. Bard, Julien Kann, Donald Yergeau, Darshan Sapkota, Yichen Ge, Zihua Hu, Jie Wang, Tao Liu, Xiuqian Mu

Nat Commun. 2021; 12: 1465. Published online 2021 Mar 5. doi: 10.1038/s41467-021-21704-4

PMCID:: PMC7935890

Abstract Article PDF–5.9M

Select item 738515912.

GADD45α drives brown adipose tissue formation through upregulating PPARγ in mice

Wenjing You, Ziye Xu, Ye Sun, Teresa G. Valencak, Yizhen Wang, Tizhong Shan

Cell Death Dis. 2020 Jul; 11(7): 585. Published online 2020 Jul 27. doi: 10.1038/s41419-020-02802-5

PMCID:: PMC7385159

Abstract Article PDF–3.4M

Select item 703205113.

TBR2 antagonizes retinoic acid dependent neuronal differentiation by repressing ZFP423 during corticogenesis

Luca Massimino, Lisbeth Flores-Garcia, Bruno Di Stefano, Gaia Colasante, Cecilia Icoresi-Mazzeo, Mattia Zaghi, Bruce A. Hamilton, Alessandro Sessa

Dev Biol. Author manuscript; available in PMC 2020 Feb 20.

Published in final edited form as: Dev Biol. 2018 Feb 15; 434(2): 231–248. Published online 2018 Jan 2. doi: 10.1016/j.ydbio.2017.12.020

PMCID:: PMC7032051

Abstract Article PDF–3.3M

Select item 660151114.

GADD45 promotes locus-specific DNA demethylation and 2C cycling in embryonic stem cells

Katrin M. Schüle, Manuel Leichsenring, Tommaso Andreani, Viviana Vastolo, Medhavi Mallick, Michael U. Musheev, Emil Karaulanov, Christof Niehrs

Genes Dev. 2019 Jul 1; 33(13-14): 782–798. doi: 10.1101/gad.325696.119

PMCID:: PMC6601511

Abstract Article PDF–5.4M

Select item 654902215.

Gadd45α modulates aversive learning through post‐transcriptional regulation of memory‐related mRNAs

Alejandro Aparisi Rey, Emil Karaulanov, Salim Sharopov, Khelifa Arab, Andrea Schäfer, Mathias Gierl, Stephan Guggenhuber, Caroline Brandes, Luigi Pennella, Wolfram H Gruhn, Ruth Jelinek, Christina Maul, Andrea Conrad, Werner Kilb, Heiko J Luhmann, Christof Niehrs, Beat Lutz

EMBO Rep. 2019 Jun; 20(6): e46022. Published online 2019 Apr 4. doi: 10.15252/embr.201846022

PMCID:: PMC6549022

Abstract Article PDF–2.5M

Select item 641197916.

Loss of SET reveals both the p53-dependent and the p53-independent functions in vivo

Ning Kon, Donglai Wang, Wei Gu

Cell Death Dis. 2019 Mar; 10(3): 237. Published online 2019 Mar 11. doi: 10.1038/s41419-019-1484-6

PMCID:: PMC6411979

Abstract Article PDF–2.3M

Select item 617246117.

Telomeric epigenetic response mediated by Gadd45a regulates stem cell aging and lifespan

Daojun Diao, Hu Wang, Tangliang Li, Zhencan Shi, Xiaoqing Jin, Tobias Sperka, Xudong Zhu, Meimei Zhang, Fan Yang, Yusheng Cong, Li Shen, Qimin Zhan, Jing Yan, Zhangfa Song, Zhenyu Ju

EMBO Rep. 2018 Oct; 19(10): e45494. Published online 2018 Aug 20. doi: 10.15252/embr.201745494

PMCID:: PMC6172461

Abstract Article PDF–2.5M

Select item 608036518.

Retinoic acid inhibits white adipogenesis by disrupting GADD45A-mediated Zfp423 DNA demethylation

B Wang, Xing Fu, Mei-Jun Zhu, Min Du

J Mol Cell Biol. 2017 Aug; 9(4): 338–349. Published online 2017 Aug 5. doi: 10.1093/jmcb/mjx026

PMCID:: PMC6080365

Abstract Article PDF–1.6M

Select item 604951319.

Impaired DNA demethylation of C/EBP sites causes premature aging

Andrea Schäfer, Bernadette Mekker, Medhavi Mallick, Viviana Vastolo, Emil Karaulanov, Dominik Sebastian, Carina von der Lippen, Bernd Epe, Damien J. Downes, Carola Scholz, Christof Niehrs

Genes Dev. 2018 Jun 1; 32(11-12): 742–762. doi: 10.1101/gad.311969.118