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Select item 116451251.

A MyD88/IL-1R axis regulates PD-1 expression on tumor-associated macrophages and sustains their immunosuppressive function in melanoma

Sarang Tartey, Geoffrey Neale, Peter Vogel, R.K. Subbarao Malireddi, Thirumala-Devi Kanneganti

Cancer Res. Author manuscript; available in PMC 2024 Dec 13.

Published in final edited form as: Cancer Res. 2021 May 1; 81(9): 2358–2372. Published online 2021 Feb 22. doi: 10.1158/0008-5472.CAN-20-3510

PMCID:: PMC11645125

Abstract Article PDF–3.4M

Select item 115034582.

Effect of genetic polymorphisms of interleukin‐1 beta on the microscopic portal vein invasion and prognosis of hepatocellular carcinoma

Yosuke Namba, Tsuyoshi Kobayashi, Takeshi Tadokoro, Sotaro Fukuhara, Ko Oshita, Keiso Matsubara, Naruhiko Honmyo, Shintaro Kuroda, Masahiro Ohira, Hideki Ohdan

J Hepatobiliary Pancreat Sci. 2024 Aug; 31(8): 528–536. Published online 2024 May 26. doi: 10.1002/jhbp.12009

PMCID:: PMC11503458

Abstract Article PDF–464K

Select item 114925623.

Gasdermin D promotes development of intestinal tumors through regulating IL-1β release and gut microbiota composition

Hanchao Gao, Weilong Li, Shi Xu, Zigan Xu, Wenjun Hu, Litao Pan, Kewang Luo, Ting Xie, Yeye Yu, Huimin Sun, Liwen Huang, Peishan Chen, Jinmei Wu, Dexing Yang, Lian Li, Shaodong Luan, Mengtao Cao, Pengfei Chen

Cell Commun Signal. 2024; 22: 511. Published online 2024 Oct 21. doi: 10.1186/s12964-024-01890-6

PMCID:: PMC11492562

Abstract Article PDF–9.8M

Select item 114530474.

Advanced paternal age exacerbates neuroinflammation in offspring via m6A modification-mediated intergenerational inheritance

Yiting Mao, Yicong Meng, Kexin Zou, Ningxin Qin, Yinyu Wang, Jing Yan, PinJia Chen, Yi Cheng, Weihui Shi, Chengliang Zhou, Huixi Chen, Jianzhong Sheng, Xinmei Liu, Jiexue Pan, Hefeng Huang

J Neuroinflammation. 2024; 21: 249. Published online 2024 Oct 4. doi: 10.1186/s12974-024-03248-8

PMCID:: PMC11453047

Abstract Article PDF–8.9M

Select item 114212095.

Tmem178 negatively regulates IL-1β production through inhibition of the NLRP3 inflammasome

Kunjan Khanna, Hui Yan, Muneshwar Mehra, Nidhi Rohatgi, Gabriel Mbalaviele, Elizabeth D. Mellins, Roberta Faccio

Arthritis Rheumatol. Author manuscript; available in PMC 2025 Jan 1.

Published in final edited form as: Arthritis Rheumatol. 2024 Jan; 76(1): 107–118. Published online 2023 Nov 13. doi: 10.1002/art.42666

PMCID:: PMC11421209

Abstract Article PDF–2.3M

Select item 113909006.

IL-1β promotes adipogenesis by directly targeting adipocyte precursors

Kaisa Hofwimmer, Joyce de Paula Souza, Narmadha Subramanian, Milica Vujičić, Leila Rachid, Hélène Méreau, Cheng Zhao, Erez Dror, Emelie Barreby, Niklas K. Björkström, Ingrid Wernstedt Asterholm, Marianne Böni-Schnetzler, Daniel T. Meier, Marc Y. Donath, Jurga Laurencikiene

Nat Commun. 2024; 15: 7957. Published online 2024 Sep 11. doi: 10.1038/s41467-024-51938-x

PMCID:: PMC11390900

Abstract Article PDF–2.2M

Select item 112876367.

ZFYVE19 deficiency: a ciliopathy involving failure of cell division, with cell death

Jing Yang, Ya-Nan Zhang, Ren-Xue Wang, Chen-Zhi Hao, Yiling Qiu, Hao Chi, Wei-Sha Luan, HongYi Tang, Xiu-Juan Zhang, XuXu Sun, Jonathan A Sheps, Victor Ling, Muqing Cao, Jian-she Wang

J Med Genet. 2024 Aug; 61(8): 750–758. Published online 2024 May 30. doi: 10.1136/jmg-2023-109779

PMCID:: PMC11287636

Abstract Article PDF–6.1M

Select item 111965838.

Neutrophil NLRP3 promotes cardiac injury following acute myocardial infarction through IL-1β production, VWF release and NET deposition in the myocardium

Lukas A. Heger, Nicolas Schommer, Stijn Van Bruggen, Casey E. Sheehy, William Chan, Denisa D. Wagner

Sci Rep. 2024; 14: 14524. Published online 2024 Jun 24. doi: 10.1038/s41598-024-64710-4

PMCID:: PMC11196583

Abstract Article PDF–3.0M

Select item 111099259.

Dual neutrophil subsets exacerbate or suppress inflammation in tuberculosis via IL-1β or PD-L1

Emilie Doz-Deblauwe, Badreddine Bounab, Florence Carreras, Julia S Fahel, Sergio C Oliveira, Mohamed Lamkanfi, Yves Le Vern, Pierre Germon, Julien Pichon, Florent Kempf, Christophe Paget, Aude Remot, Nathalie Winter

Life Sci Alliance. 2024 Jul; 7(7): e202402623. Published online 2024 May 21. doi: 10.26508/lsa.202402623

PMCID:: PMC11109925

Abstract Article PDF–2.8M

Select item 1106225210.

Frontline Science: Anthrax lethal toxin-induced, NLRP1-mediated IL-1β release is a neutrophil and PAD4-dependent event

Allison J. Greaney, Makayla K. Portley, Danielle O’Mard, Devorah Crown, Nolan K. Maier, Megan A. Mendenhall, Katrin D. Mayer-Barber, Stephen H. Leppla, Mahtab Moayeri

J Leukoc Biol. Author manuscript; available in PMC 2024 May 1.

Published in final edited form as: J Leukoc Biol. 2020 Sep; 108(3): 773–786. Published online 2020 May 18. doi: 10.1002/JLB.4HI0320-028R

PMCID:: PMC11062252

Abstract Article PDF–1.0M

Select item 1091448911.

P2X7 receptor inhibition alleviates mania-like behavior independently of interleukin-1β

Flóra Gölöncsér, Mária Baranyi, Pál Tod, Fruzsina Maácz, Beáta Sperlágh

iScience. 2024 Mar 15; 27(3): 109284. Published online 2024 Feb 20. doi: 10.1016/j.isci.2024.109284

PMCID:: PMC10914489

Abstract Article PDF–6.2M

Select item 1091285012.

IL-1β promotes MPN disease initiation by favoring early clonal expansion of JAK2-mutant hematopoietic stem cells

Shivam Rai, Yang Zhang, Elodie Grockowiak, Quentin Kimmerlin, Nils Hansen, Cedric B. Stoll, Marc Usart, Damien Luque Paz, Hui Hao-Shen, Yexuan Zhu, Julien Roux, Michael S. Bader, Stefan Dirnhofer, Christopher J. Farady, Timm Schroeder, Simón Méndez-Ferrer, Radek C. Skoda

Blood Adv. 2024 Mar 12; 8(5): 1234–1249. Published online 2024 Jan 13. doi: 10.1182/bloodadvances.2023011338

PMCID:: PMC10912850

Abstract Article PDF–6.0M

Select item 1083437013.

A pairwise cytokine code explains the organism-wide response to sepsis

Michihiro Takahama, Ashwini Patil, Gabriella Richey, Denis Cipurko, Katherine Johnson, Peter Carbonetto, Madison Plaster, Surya Pandey, Katerina Cheronis, Tatsuki Ueda, Adam Gruenbaum, Tadafumi Kawamoto, Matthew Stephens, Nicolas Chevrier

Nat Immunol. 2024; 25(2): 226–239. Published online 2024 Jan 8. doi: 10.1038/s41590-023-01722-8

PMCID:: PMC10834370

Abstract Article PDF–13M

Select item 1082694814.

Salmonella manipulates the host to drive pathogenicity via induction of interleukin 1β

Mor Zigdon, Jasmin Sawaed, Lilach Zelik, Dana Binyamin, Shira Ben-Simon, Nofar Asulin, Rachel Levin, Sonia Modilevsky, Maria Naama, Shahar Telpaz, Elad Rubin, Aya Awad, Wisal Sawaed, Sarina Harshuk-Shabso, Meital Nuriel-Ohayon, Mathumathi Krishnamohan, Michal Werbner, Omry Koren, Sebastian E. Winter, Ron N. Apte, Elena Voronov, Shai Bel

PLoS Biol. 2024 Jan; 22(1): e3002486. Published online 2024 Jan 18. doi: 10.1371/journal.pbio.3002486

PMCID:: PMC10826948

Abstract Article PDF–3.7M

Select item 1079272915.

A discrete “early-responder” stromal-cell subtype orchestrates immunocyte recruitment to injured tissue

Omar K. Yaghi, Bola S. Hanna, P. Kent Langston, Daniel A. Michelson, Teshika Jayewickreme, Miguel Marin-Rodero, Christophe Benoist, Diane Mathis

Nat Immunol. Author manuscript; available in PMC 2024 Jun 1.

Published in final edited form as: Nat Immunol. 2023 Dec; 24(12): 2053–2067. Published online 2023 Nov 6. doi: 10.1038/s41590-023-01669-w

PMCID:: PMC10792729

Abstract Article PDF–5.5M

Select item 1078779116.

Loss of Mptx2 alters bacteria composition and intestinal homeostasis potentially by impairing autophagy

Weihui Yan, Shanshan Chen, Ying Wang, Yaying You, Ying Lu, Weipeng Wang, Bo Wu, Jun Du, Shicheng Peng, Wei Cai, Yongtao Xiao

Commun Biol. 2024; 7: 94. Published online 2024 Jan 13. doi: 10.1038/s42003-024-05785-7

PMCID:: PMC10787791

Abstract Article PDF–21M

Select item 1077110917.

Inhibiting mtDNA‐STING‐NLRP3/IL‐1β axis‐mediated neutrophil infiltration protects neurons in Alzheimer's disease

Xiangyu Xia, Xuemei He, Tingmei Zhao, Jingyun Yang, Zhenfei Bi, Qianmei Fu, Jian Liu, Danyi Ao, Yuquan Wei, Xiawei Wei

Cell Prolif. 2024 Jan; 57(1): e13529. Published online 2023 Aug 1. doi: 10.1111/cpr.13529

PMCID:: PMC10771109

Abstract Article PDF–6.7M

Select item 1076154418.

Transcriptome analysis of the cerebral cortex of acrylamide-exposed wild-type and IL-1β-knockout mice

Alzahraa Fergany, Cai Zong, Frederick Adams Ekuban, Bin Wu, Satoshi Ueha, Shigeyuki Shichino, Kouji Matsushima, Yoichiro Iwakura, Sahoko Ichihara, Gaku Ichihara

Arch Toxicol. 2024; 98(1): 181–205. Published online 2023 Nov 16. doi: 10.1007/s00204-023-03627-9

PMCID:: PMC10761544

Abstract Article PDF–1.8M

Select item 1069980619.

Apoptotic signaling clears engineered Salmonella in an organ-specific manner

Taylor J Abele, Zachary P Billman, Lupeng Li, Carissa K Harvest, Alexia K Bryan, Gabrielle R Magalski, Joseph P Lopez, Heather N Larson, Xiao-Ming Yin, Edward A Miao

eLife. 2023; 12: RP89210. Published online 2023 Dec 6. doi: 10.7554/eLife.89210

PMCID:: PMC10699806

Abstract Article PDF–4.4M

Select item 1065585920.

Myeloid Cell Derived IL1β Contributes to Pulmonary Hypertension in HFpEF

Vineet Agrawal, Jonathan A. Kropski, Jason J. Gokey, Elizabeth Kobeck, Matthew B. Murphy, Katherine T. Murray, Niki L. Fortune, Christy S. Moore, David F. Meoli, Ken Monahan, Yan Ru Su, Thomas Blackwell, Deepak K. Gupta, Megha H. Talati, Santhi Gladson, Erica J. Carrier, James D. West, Anna R. Hemnes

Circ Res. Author manuscript; available in PMC 2024 Nov 10.

Published in final edited form as: Circ Res. 2023 Nov 10; 133(11): 885–898. Published online 2023 Nov 6. doi: 10.1161/CIRCRESAHA.123.323119

PMCID:: PMC10655859

Abstract Article PDF–3.0M

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