PMC Links for GEO Profiles (Select 115257798) - PMC

Anita Bodac, Abdullah Mayet, Sarika Rana, Justine Pascual, Amber D Bowler, Vincent Roh, Nadine Fournier, Ligia Craciun, Pieter Demetter, Freddy Radtke, Etienne Meylan

EMBO Mol Med. 2024 Jan; 16(1): 158–184. Published online 2023 Dec 20. doi: 10.1038/s44321-023-00013-x

PMCID:: PMC10897164

Abstract Article PDF–8.1M

Select item 107435714.

Bcl2l1 Deficiency in Osteoblasts Reduces the Trabecular Bone Due to Enhanced Osteoclastogenesis Likely through Osteoblast Apoptosis

Takeshi Moriishi, Yosuke Kawai, Ryo Fukuyama, Yuki Matsuo, You-Wen He, Haruhiko Akiyama, Izumi Asahina, Toshihisa Komori

Int J Mol Sci. 2023 Dec; 24(24): 17319. Published online 2023 Dec 10. doi: 10.3390/ijms242417319

PMCID:: PMC10743571

Abstract Article PDF–3.7M

Select item 105092655.

Ser14 phosphorylation of Bcl-xL mediates compensatory cardiac hypertrophy in male mice

Michinari Nakamura, Mariko Aoyagi Keller, Nadezhda Fefelova, Peiyong Zhai, Tong Liu, Yimin Tian, Shohei Ikeda, Dominic P. Del Re, Hong Li, Lai-Hua Xie, Junichi Sadoshima

Nat Commun. 2023; 14: 5805. Published online 2023 Sep 19. doi: 10.1038/s41467-023-41595-x

PMCID:: PMC10509265

Abstract Article PDF–5.8M

Select item 103308936.

Burn-Induced Apoptosis in the Livers of Aged Mice is Associated with Caspase Cleavage of Bcl-xL

Israel Muro, Andrea C. Qualman, Elizabeth J. Kovacs, Juan-Pablo Idrovo

J Surg Res. Author manuscript; available in PMC 2024 Oct 1.

Published in final edited form as: J Surg Res. 2023 Oct; 290: 147–155. Published online 2023 May 31. doi: 10.1016/j.jss.2023.04.020

PMCID:: PMC10330893

Abstract Article PDF–1.0M

Select item 101752457.

Genetically prolonged beige fat in male mice confers long-lasting metabolic health

Ruifan Wu, Jooman Park, Yanyu Qian, Zuoxiao Shi, Ruoci Hu, Yexian Yuan, Shaolei Xiong, Zilai Wang, Gege Yan, Sang-Ging Ong, Qing Song, Zhenyuan Song, Abeer M. Mahmoud, Pingwen Xu, Congcong He, Robert W. Arpke, Michael Kyba, Gang Shu, Qingyan Jiang, Yuwei Jiang

Nat Commun. 2023; 14: 2731. Published online 2023 May 12. doi: 10.1038/s41467-023-38471-z

PMCID:: PMC10175245

Abstract Article PDF–6.7M

Select item 100300458.

BCL-xL inhibition potentiates cancer therapies by redirecting the outcome of p53 activation from senescence to apoptosis

Vijaya Bharti, Reese Watkins, Amrendra Kumar, Rebecca L. Shattuck-Brandt, Alexis Mossing, Arjun Mittra, Chengli Shen, Allan Tsung, Alex Davies, Walter Hanel, John C. Reneau, Catherine Chung, Gina M. Sizemore, Ann Richmond, Vivian L. Weiss, Anna E. Vilgelm

Cell Rep. Author manuscript; available in PMC 2023 Mar 21.

Published in final edited form as: Cell Rep. 2022 Dec 20; 41(12): 111826. doi: 10.1016/j.celrep.2022.111826

PMCID:: PMC10030045

Abstract Article PDF–4.7M

Select item 98083749.

Bcl-xL Is a Key Mediator of Apoptosis Following KRAS^G12C Inhibition in KRAS^G12C-mutant Colorectal Cancer

Hajrah Khawaja, Rebecca Briggs, Cheryl H. Latimer, Mustasin Rassel, Daryl Griffin, Lyndsey Hanson, Alberto Bardelli, Frederica Di Nicolantonio, Simon S. McDade, Christopher J. Scott, Shauna Lambe, Manisha Maurya, Andreas U. Lindner, Jochen H.M. Prehn, Jose Sousa, Chris Winnington, Melissa J. LaBonte, Sarah Ross, Sandra Van Schaeybroeck

Mol Cancer Ther. 2023 Jan 3; 22(1): 135–149. Published online 2022 Oct 22. doi: 10.1158/1535-7163.MCT-22-0301

PMCID:: PMC9808374

Abstract Article PDF–16M

Select item 909121710.

Loss of TAF8 causes TFIID dysfunction and p53-mediated apoptotic neuronal cell death

Farrah El-Saafin, Maria I. Bergamasco, Yunshun Chen, Rose E. May, Prabagaran Esakky, Soroor Hediyeh-zadeh, Mathew Dixon, Stephen Wilcox, Melissa J. Davis, Andreas Strasser, Gordon K. Smyth, Tim Thomas, Anne K. Voss

Cell Death Differ. 2022 May; 29(5): 1013–1027. Published online 2022 Mar 31. doi: 10.1038/s41418-022-00982-5

PMCID:: PMC9091217

Abstract Article PDF–7.2M

Select item 901455911.

Functional genomic landscape of cancer-intrinsic evasion of killing by T cells

Keith A. Lawson, Cristovão M. Sousa, Xiaoyu Zhang, Eiru Kim, Rummy Akthar, Joseph J. Caumanns, Yuxi Yao, Nicholas Mikolajewicz, Catherine Ross, Kevin R. Brown, Abdelrahman Abou Zid, Zi Peng Fan, Shirley Hui, Jordan A. Krall, Donald M. Simons, Chloe J. Slater, Victor De Jesus, Lujia Tang, Richa Singh, Joshua E. Goldford, Sarah Martin, Qian Huang, Elizabeth A. Francis, Andrea Habsid, Ryan Climie, David Tieu, Jiarun Wei, Ren Li, Amy Hin Yan Tong, Michael Aregger, Katherine S. Chan, Hong Han, Xiaowei Wang, Patricia Mero, John H. Brumell, Antonio Finelli, Laurie Ailles, Gary Bader, Gromoslaw A. Smolen, Gillian A. Kingsbury, Traver Hart, Charles Kung, Jason Moffat

Nature. Author manuscript; available in PMC 2022 Apr 18.

Published in final edited form as: Nature. 2020 Oct; 586(7827): 120–126. Published online 2020 Sep 23. doi: 10.1038/s41586-020-2746-2

PMCID:: PMC9014559

Abstract Article PDF–6.6M

Select item 894121212.

Counteractive and cooperative actions of muscle β-catenin and Ca_V1.1 during early neuromuscular synapse formation

Mehmet Mahsum Kaplan, Bernhard E. Flucher

iScience. 2022 Apr 15; 25(4): 104025. Published online 2022 Mar 4. doi: 10.1016/j.isci.2022.104025

PMCID:: PMC8941212

Abstract Article PDF–6.5M

Select item 882106713.

CDNF and MANF regulate ER stress in a tissue-specific manner

Emmi Pakarinen, Päivi Lindholm, Mart Saarma, Maria Lindahl

Cell Mol Life Sci. 2022 Feb; 79(2): 124. Published online 2022 Feb 7. doi: 10.1007/s00018-022-04157-w

PMCID:: PMC8821067

Abstract Article PDF–5.4M

Select item 881935314.

Suppression of multiple anti‐apoptotic BCL2 family proteins recapitulates the effects of JAK2 inhibitors in JAK2V617F driven myeloproliferative neoplasms

Hisashi Takei, Juan Luiz Coelho‐Silva, Cristina Tavares Leal, Adriana Queiroz Arantes Rocha, Thiago Mantello Bianco, Robert S. Welner, Yuta Mishima, Ikei S. Kobayashi, Ann Mullally, Keli Lima, João Agostinho Machado‐Neto, Susumu S. Kobayashi, Lorena Lobo de Figueiredo‐Pontes

Cancer Sci. 2022 Feb; 113(2): 597–608. Published online 2021 Dec 15. doi: 10.1111/cas.15210

PMCID:: PMC8819353

Abstract Article PDF–1.8M

Select item 808632015.

ZBTB28 induces autophagy by regulation of FIP200 and Bcl-XL facilitating cervical cancer cell apoptosis

Li Li, Yijia Gong, Ke Xu, Weihong Chen, Jiuyi Xia, Zhaobo Cheng, Lili Li, Renjie Yu, Junhao Mu, Xin Le, Qin Xiang, Weiyan Peng, Junying Tang, Tingxiu Xiang

J Exp Clin Cancer Res. 2021; 40: 150. Published online 2021 Apr 30. doi: 10.1186/s13046-021-01948-0

PMCID:: PMC8086320

Abstract Article PDF–8.8M

Select item 805863516.

RORγt limits the amount of the cytokine receptor γc through the prosurvival factor Bcl-x_L in developing thymocytes

Davinna L. Ligons, SuJin Hwang, Adam T. Waickman, Joo-Young Park, Megan A. Luckey, Jung-Hyun Park

Sci Signal. Author manuscript; available in PMC 2021 Apr 21.

Published in final edited form as: Sci Signal. 2018 Aug 28; 11(545): eaam8939. Published online 2018 Aug 28. doi: 10.1126/scisignal.aam8939

PMCID:: PMC8058635

Abstract Article PDF–1.5M

Select item 805030217.

Malignant pleural mesothelioma co-opts BCL-X_L and autophagy to escape apoptosis

Duo Xu, Shun-Qing Liang, Zhang Yang, Haitang Yang, Rémy Bruggmann, Simone Oberhaensli, Sabina Berezowska, Thomas M. Marti, Sean R. R. Hall, Patrick Dorn, Gregor J. Kocher, Ralph A. Schmid, Ren-Wang Peng

Cell Death Dis. 2021 Apr; 12(4): 406. Published online 2021 Apr 15. doi: 10.1038/s41419-021-03668-x

PMCID:: PMC8050302

Abstract Article PDF–3.2M

Select item 793877018.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 773761619.

BCL‐XL exerts a protective role against anemia caused by radiation‐induced kidney damage

Kerstin Brinkmann, Paul Waring, Stefan P Glaser, Verena Wimmer, Denny L Cottle, Ming Shen Tham, Duong Nhu, Lachlan Whitehead, Alex RD Delbridge, Guillaume Lessene, Ian M Smyth, Marco J Herold, Gemma L Kelly, Stephanie Grabow, Andreas Strasser

EMBO J. 2020 Dec 15; 39(24): e105561. Published online 2020 Nov 25. doi: 10.15252/embj.2020105561

PMCID:: PMC7737616

Abstract Article PDF–3.8M

Select item 772839420.

Runx2 is essential for the transdifferentiation of chondrocytes into osteoblasts

Xin Qin, Qing Jiang, Kenichi Nagano, Takeshi Moriishi, Toshihiro Miyazaki, Hisato Komori, Kosei Ito, Klaus von der Mark, Chiharu Sakane, Hitomi Kaneko, Toshihisa Komori

PLoS Genet. 2020 Nov; 16(11): e1009169. Published online 2020 Nov 30. doi: 10.1371/journal.pgen.1009169

PMCID:: PMC7728394

Abstract Article PDF–10M

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