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Select item 112965461.

LGG promotes activation of intestinal ILC3 through TLR2 receptor and inhibits salmonella typhimurium infection in mice

Junhong Wang, Ming Gao, Jiarui Wang, Yan Zeng, Chunfeng Wang, Xin Cao

Virulence. 2024; 15(1): 2384553. Published online 2024 Jul 30. doi: 10.1080/21505594.2024.2384553

PMCID:: PMC11296546

Abstract Article PDF–6.8M

Select item 110783962.

Impaired upper respiratory tract barrier function during postnatal development predisposes to invasive pneumococcal disease

Kristen L. Lokken-Toyli, Surya D. Aggarwal, Gavyn Chern Wei Bee, Wouter A. A. de Steenhuijsen Piters, Cindy Wu, Kenny Zhi Ming Chen, Cynthia Loomis, Debby Bogaert, Jeffrey N. Weiser

PLoS Pathog. 2024 May; 20(5): e1012111. Published online 2024 May 8. doi: 10.1371/journal.ppat.1012111

PMCID:: PMC11078396

Abstract Article PDF–3.6M

Select item 109176603.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 108971704.

DDX5 inhibits inflammation by modulating m6A levels of TLR2/4 transcripts during bacterial infection

Jian Xu, Li-Yuan Liu, Fei-Jie Zhi, Yin-Juan Song, Zi-Hui Zhang, Bin Li, Fu-Ying Zheng, Peng-Cheng Gao, Su-Zi Zhang, Yu-Yu Zhang, Ying Zhang, Ying Qiu, Bo Jiang, Yong-Qing Li, Chen Peng, Yue-Feng Chu

EMBO Rep. 2024 Feb; 25(2): 770–795. Published online 2024 Jan 5. doi: 10.1038/s44319-023-00047-9

PMCID:: PMC10897170

Abstract Article PDF–7.5M

Select item 107908235.

Impact of surface receptors TLR2, CR3, and FcγRIII on Rhodococcus equi phagocytosis and intracellular survival in macrophages

Bibiana Petri da Silveira, Rola Barhoumi, Jocelyne M. Bray, Hannah M. Cole-Pfeiffer, Cory J. Mabry, Robert C. Burghardt, Noah D. Cohen, Angela I. Bordin

Infect Immun. 2024 Jan; 92(1): e00383-23. Published online 2023 Nov 29. doi: 10.1128/iai.00383-23

PMCID:: PMC10790823

Abstract Article PDF–4.6M

Select item 107729376.

TLR2 regulates Moraxella catarrhalis adhesion to and invasion into alveolar epithelial cells and mediates inflammatory responses

Rui Ding, Jinhan Yu, Weixin Ke, Lijun Du, Guixue Cheng, Siqi Hu, Yingchun Xu, Yali Liu

Virulence. 2024; 15(1): 2298548. Published online 2024 Jan 3. doi: 10.1080/21505594.2023.2298548

PMCID:: PMC10772937

Abstract Article PDF–3.6M

Select item 107164707.

Aging exacerbates cardiac dysfunction and mortality in sepsis through enhancing TLR2 activity

Yufeng Zhai, Qingzhou Yao, Erlinda The, Lihua Ao, David A. Fullerton, Xianzhong Meng

Front Cardiovasc Med. 2023; 10: 1293866. Published online 2023 Nov 29. doi: 10.3389/fcvm.2023.1293866

PMCID:: PMC10716470

Abstract Article PDF–2.8M

Select item 106840738.

TLR2 mediates renal apoptosis in neonatal mice subjected experimentally to obstructive nephropathy

Maja Wyczanska, Jana Rohling, Ursula Keller, Marcus R. Benz, Carsten Kirschning, Bärbel Lange-Sperandio

PLoS One. 2023; 18(11): e0294142. Published online 2023 Nov 28. doi: 10.1371/journal.pone.0294142

PMCID:: PMC10684073

Abstract Article PDF–4.2M

Select item 105938189.

C-type lectin receptor 2d forms homodimers and heterodimers with TLR2 to negatively regulate IRF5-mediated antifungal immunity

Fan Li, Hui Wang, Yan-Qi Li, Yebo Gu, Xin-Ming Jia

Nat Commun. 2023; 14: 6718. Published online 2023 Oct 23. doi: 10.1038/s41467-023-42216-3

PMCID:: PMC10593818

Abstract Article PDF–3.3M

Select item 1054716910.

Akkermansia muciniphila participates in the host protection against helminth-induced cardiac fibrosis via TLR2

Jiaqi Wang, Xiaolei Liu, Ruohang Sun, Hanhai Mao, Mingyuan Liu, Xuemin Jin

PLoS Pathog. 2023 Oct; 19(10): e1011683. Published online 2023 Oct 3. doi: 10.1371/journal.ppat.1011683

PMCID:: PMC10547169

Abstract Article PDF–4.1M

Select item 1050647411.

TLR2 is non-redundant in the population and subpopulation responses to Mycobacterium tuberculosis in macrophages and in vivo

Charul Jani, Sydney L. Solomon, Joshua M. Peters, Stephanie C. Pringle, Amelia E. Hinman, Julie Boucau, Bryan D. Bryson, Amy K. Barczak

mSystems. 2023 Jul-Aug; 8(4): e00052-23. Published online 2023 Jul 13. doi: 10.1128/msystems.00052-23

PMCID:: PMC10506474

Abstract Article PDF–2.5M

Select item 1050381112.

Tau fibrils induce glial inflammation and neuropathology via TLR2 in Alzheimer’s disease–related mouse models

Debashis Dutta, Malabendu Jana, Ramesh Kumar Paidi, Moumita Majumder, Sumita Raha, Sridevi Dasarathy, Kalipada Pahan

J Clin Invest. 2023 Sep 15; 133(18): e161987. Published online 2023 Sep 15. doi: 10.1172/JCI161987

PMCID:: PMC10503811

Abstract Article PDF–29M

Select item 1050272613.

Co-infection of mice with SARS-CoV-2 and Mycobacterium tuberculosis limits early viral replication but does not affect mycobacterial loads

Paul J. Baker, Eduardo P. Amaral, Ehydel Castro, Andrea C. Bohrer, Flor Torres-Juárez, Cassandra M. Jordan, Christine E. Nelson, Daniel L. Barber, Reed F. Johnson, Kerry L. Hilligan, Katrin D. Mayer-Barber

Front Immunol. 2023; 14: 1240419. Published online 2023 Sep 1. doi: 10.3389/fimmu.2023.1240419

PMCID:: PMC10502726

Abstract Article PDF–9.6M

Select item 1049147914.

MyD88-dependent Toll-like receptor 2 signaling modulates macrophage activation on lysate-adsorbed Teflon™ AF surfaces in an in vitro biomaterial host response model

Laura A. McKiel, Laurel L. Ballantyne, Gian Luca Negri, Kimberly A. Woodhouse, Lindsay E. Fitzpatrick

Front Immunol. 2023; 14: 1232586. Published online 2023 Aug 24. doi: 10.3389/fimmu.2023.1232586

PMCID:: PMC10491479

Abstract Article PDF–5.6M

Select item 1024039215.

Toll-like receptors 2, 4, and 9 modulate promoting effect of COPD-like airway inflammation on K-ras-driven lung cancer through activation of the MyD88/NF-ĸB pathway in the airway epithelium

Walter V. Velasco, Nasim Khosravi, Susana Castro-Pando, Nelly Torres-Garza, Maria T. Grimaldo, Avantika Krishna, Michael J. Clowers, Misha Umer, Sabah Tariq Amir, Diana Del Bosque, Soudabeh Daliri, Maria Miguelina De La Garza, Marco Ramos-Castaneda, Scott E. Evans, Seyed Javad Moghaddam

Front Immunol. 2023; 14: 1118721. Published online 2023 May 22. doi: 10.3389/fimmu.2023.1118721

PMCID:: PMC10240392

Abstract Article PDF–3.5M

Select item 1023251916.

The impact of TLR2 and aging on the humoral immune response to Staphylococcus aureus bacteremia in mice

Priti Gupta, Zhicheng Hu, Pradeep Kumar Kopparapu, Meghshree Deshmukh, Tibor Sághy, Majd Mohammad, Tao Jin, Cecilia Engdahl

Sci Rep. 2023; 13: 8850. Published online 2023 May 31. doi: 10.1038/s41598-023-35970-3

PMCID:: PMC10232519

Abstract Article PDF–1.4M

Select item 1022668017.

Gut commensal bacteria enhance pathogenesis of a tumorigenic murine retrovirus

Jessica Spring, Aly A. Khan, Sophie Lara, Kelly O’Grady, Jessica Wilks, Sandeep Gurbuxani, Steven Erickson, Michael Fischbach, Amy Jacobson, Alexander Chervonsky, Tatyana Golovkina

Cell Rep. Author manuscript; available in PMC 2023 May 29.

Published in final edited form as: Cell Rep. 2022 Sep 13; 40(11): 111341. doi: 10.1016/j.celrep.2022.111341

PMCID:: PMC10226680

Abstract Article PDF–1.1M

Select item 1019742718.

Toll-like receptor 2 orchestrates a tumor suppressor response in non-small cell lung cancer

Fraser R. Millar, Adam Pennycuick, Morwenna Muir, Andrea Quintanilla, Priya Hari, Elisabeth Freyer, Philippe Gautier, Alison Meynert, Graeme Grimes, Carla Salomo Coll, Sofia Zdral, Stella Victorelli, Vitor H. Teixeira, John Connelly, João F. Passos, Marian A. Ros, William A.H. Wallace, Margaret C. Frame, Andrew H. Sims, Luke Boulter, Sam M. Janes, Simon Wilkinson, Juan Carlos Acosta

Cell Rep. Author manuscript; available in PMC 2023 May 19.

Published in final edited form as: Cell Rep. 2022 Nov 8; 41(6): 111596. doi: 10.1016/j.celrep.2022.111596

PMCID:: PMC10197427

Abstract Article PDF–1.2M

Select item 1018357519.

TLR4 activation by lysozyme induces pain without inflammation

Saurabh Yadav, Amrita Singh, Ravi Kant, Avadhesha Surolia

Front Immunol. 2023; 14: 1065226. Published online 2023 May 1. doi: 10.3389/fimmu.2023.1065226

PMCID:: PMC10183575

Abstract Article PDF–3.8M

Select item 1003890220.

IL-1/MyD88-Dependent G-CSF and IL-6 Secretion Mediates Post Burn Anemia

John G. Noel, Seth W. Ramser, Lori Pitstick, Holly S. Goetzman, Elizabeth L. Dale, Andrew Potter, Mike Adam, S. Steven Potter, Jason C. Gardner

J Immunol. Author manuscript; available in PMC 2024 Apr 1.

Published in final edited form as: J Immunol. 2023 Apr 1; 210(7): 972–980. doi: 10.4049/jimmunol.2200785

PMCID:: PMC10038902

Abstract Article PDF–2.2M

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