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Select item 111110101.

KLRG1-expressing CD8+ T cells are exhausted and polyfunctional in patients with chronic hepatitis B

Li Wang, Fangli Liao, Liping Yang, Linshan Jiang, Liang Duan, Bo Wang, Di Mu, Juan Chen, Ying Huang, Qin Hu, Weixian Chen

PLoS One. 2024; 19(5): e0303945. Published online 2024 May 22. doi: 10.1371/journal.pone.0303945

PMCID:: PMC11111010

Abstract Article PDF–3.7M

Select item 110293472.

Expanded CD8⁺ T cells of murine and human CLL are driven into a senescent KLRG1⁺ effector memory phenotype

Joachim Rudolf Göthert, Lewin Eisele, Ludger Klein-Hitpass, Stefanie Weber, Marie-Louise Zesewitz, Ludger Sellmann, Alexander Röth, Hanspeter Pircher, Ulrich Dührsen, Jan Dürig

Cancer Immunol Immunother. 2013 Nov; 62(11): 1697–1709. Published online 2013 Sep 11. doi: 10.1007/s00262-013-1473-z

PMCID:: PMC11029347

Abstract Article PDF–1.3M

Select item 105910433.

KLRG1 expression on natural killer cells is associated with HIV persistence, and its targeting promotes the reduction of the viral reservoir

Antonio Astorga-Gamaza, David Perea, Nerea Sanchez-Gaona, Marta Calvet-Mirabent, Ana Gallego-Cortés, Judith Grau-Expósito, Ildefonso Sanchez-Cerrillo, Joan Rey, Josep Castellví, Adrian Curran, Joaquin Burgos, Jordi Navarro, Paula Suanzes, Vicenç Falcó, Meritxell Genescà, Enrique Martín-Gayo, Maria J. Buzon

Cell Rep Med. 2023 Oct 17; 4(10): 101202. Published online 2023 Sep 22. doi: 10.1016/j.xcrm.2023.101202

PMCID:: PMC10591043

Abstract Article PDF–5.5M

Select item 94722114.

N-cadherin protects oral cancer cells from NK cell killing in the circulation by inducing NK cell functional exhaustion via the KLRG1 receptor

Chao Lou, Kailiu Wu, Jianbo Shi, Zhenlin Dai, Qin Xu

J Immunother Cancer. 2022; 10(9): e005061. Published online 2022 Sep 12. doi: 10.1136/jitc-2022-005061

PMCID:: PMC9472211

Abstract Article PDF–7.8M

Select item 90039705.

Increased expression of TIGIT and KLRG1 correlates with impaired CD56^bright NK cell immunity in HPV16-related cervical intraepithelial neoplasia

You Nie, Dandan Liu, Wen Yang, Yazhuo Li, Lihua Zhang, Xia Cheng, Ruyu Chen, Bingbing Yuan, Guangzheng Zhang, Hongwei Wang

Virol J. 2022; 19: 68. Published online 2022 Apr 12. doi: 10.1186/s12985-022-01776-4

PMCID:: PMC9003970

Abstract Article PDF–4.7M

Select item 82586696.

Expression of KLRG1 and CD127 defines distinct CD8⁺ subsets that differentially impact patient outcome in follicular lymphoma

Hongyan Wu, Xinyi Tang, Hyo Jin Kim, Shahrzad Jalali, Joshua C Pritchett, Jose C Villasboas, Anne J Novak, Zhi-Zhang Yang, Stephen M Ansell

J Immunother Cancer. 2021; 9(7): e002662. Published online 2021 Jul 5. doi: 10.1136/jitc-2021-002662

PMCID:: PMC8258669

Abstract Article PDF–12M

Select item 82437577.

Functions and clinical significance of KLRG1 in the development of lung adenocarcinoma and immunotherapy

Xiaodong Yang, Yuexin Zheng, Zhihai Han, Xiliang Zhang

BMC Cancer. 2021; 21: 752. Published online 2021 Jun 29. doi: 10.1186/s12885-021-08510-3

PMCID:: PMC8243757

Abstract Article PDF–2.6M

Select item 76465638.

An atlas of immune cell exhaustion in HIV-infected individuals revealed by single-cell transcriptomics

Shaobo Wang, Qiong Zhang, Hui Hui, Kriti Agrawal, Maile Ann Young Karris, Tariq M. Rana

Emerg Microbes Infect. 2020; 9(1): 2333–2347. Published online 2020 Nov 2. doi: 10.1080/22221751.2020.1826361

PMCID:: PMC7646563

Abstract Article PDF–3.6M

Select item 72354489.

KLRG1 and CD103 Expressions Define Distinct Intestinal Tissue-Resident Memory CD8 T Cell Subsets Modulated in Crohn's Disease

Hugo Bottois, Marjolaine Ngollo, Nassim Hammoudi, Tristan Courau, Julie Bonnereau, Victor Chardiny, Céline Grand, Brice Gergaud, Matthieu Allez, Lionel Le Bourhis

Front Immunol. 2020; 11: 896. Published online 2020 May 12. doi: 10.3389/fimmu.2020.00896

PMCID:: PMC7235448

Abstract Article PDF–2.1M

Select item 716998310.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x

PMCID:: PMC7169983

Abstract Article PDF–5.4M

Select item 708194511.

Early KLRG1⁺ but not CD57⁺CD8⁺ T cells in Primary CMV Infection Predict Effector Function and Viral Control

Aki Hoji, Iulia D. Popescu, Mathew R. Pipeling, Pali D. Shah, Spencer A. Winters, John F. McDyer

J Immunol. Author manuscript; available in PMC 2020 Oct 15.

Published in final edited form as: J Immunol. 2019 Oct 15; 203(8): 2063–2075. Published online 2019 Sep 25. doi: 10.4049/jimmunol.1900399

PMCID:: PMC7081945

Abstract Article PDF–1.9M

Select item 648323012.

Increased KLRG1 and PD-1 expression on CD8 T lymphocytes in TB-IRIS

Odin Goovaerts, Marguerite Massinga-Loembé, Pascale Ondoa, Ann Ceulemans, William Worodria, Harriet Mayanja-Kizza, Robert Colebunders, Luc Kestens, for the TB-IRIS Study Group

PLoS One. 2019; 14(4): e0215991. Published online 2019 Apr 25. doi: 10.1371/journal.pone.0215991

PMCID:: PMC6483230

Abstract Article PDF–1008K

Select item 530868113.

KLRG1 restricts memory T cell antitumor immunity

Lei Li, Shanshan Wan, Kaixiong Tao, Guobin Wang, Ende Zhao

Oncotarget. 2016 Sep 20; 7(38): 61670–61678. Published online 2016 Aug 20. doi: 10.18632/oncotarget.11430

PMCID:: PMC5308681

Abstract Article PDF–7.8M

Select item 502791514.

Killer Cell Lectin-like Receptor G1 (KLRG1) inhibits NK cell function through activation of AMP-activated Protein Kinase

Bojana Müller-Durovic, Alessio Lanna, Luciana Polaco Covre, Rachel S. Mills, Sian M. Henson, Arne N. Akbar

J Immunol. Author manuscript; available in PMC 2017 Apr 1.

Published in final edited form as: J Immunol. 2016 Oct 1; 197(7): 2891–2899. Published online 2016 Aug 26. doi: 10.4049/jimmunol.1600590

PMCID:: PMC5027915

Abstract Article PDF–1.5M

Select item 499781115.

A 3’UTR polymorphism marks differential KLRG1 mRNA levels through disruption of a miR-584-5p binding site and associates with pemphigus foliaceus susceptibility

Gabriel A. Cipolla, Jong K. Park, Liana A. de Oliveira, Sara Cristina Lobo-Alves, Rodrigo C. de Almeida, Ticiana D. J. Farias, Débora de S. Lemos, Danielle Malheiros, Robert M. Lavker, Maria Luiza Petzl-Erler

Biochim Biophys Acta. Author manuscript; available in PMC 2017 Oct 1.

Published in final edited form as: Biochim Biophys Acta. 2016 Oct; 1859(10): 1306–1313. Published online 2016 Jul 14. doi: 10.1016/j.bbagrm.2016.07.006

PMCID:: PMC4997811

Abstract Article PDF–1.5M

Select item 426658816.

A proteome-scale map of the human interactome network

Thomas Rolland, Murat Taşan, Benoit Charloteaux, Samuel J. Pevzner, Quan Zhong, Nidhi Sahni, Song Yi, Irma Lemmens, Celia Fontanillo, Roberto Mosca, Atanas Kamburov, Susan D. Ghiassian, Xinping Yang, Lila Ghamsari, Dawit Balcha, Bridget E. Begg, Pascal Braun, Marc Brehme, Martin P. Broly, Anne-Ruxandra Carvunis, Dan Convery-Zupan, Roser Corominas, Jasmin Coulombe-Huntington, Elizabeth Dann, Matija Dreze, Amélie Dricot, Changyu Fan, Eric Franzosa, Fana Gebreab, Bryan J. Gutierrez, Madeleine F. Hardy, Mike Jin, Shuli Kang, Ruth Kiros, Guan Ning Lin, Katja Luck, Andrew MacWilliams, Jörg Menche, Ryan R. Murray, Alexandre Palagi, Matthew M. Poulin, Xavier Rambout, John Rasla, Patrick Reichert, Viviana Romero, Elien Ruyssinck, Julie M. Sahalie, Annemarie Scholz, Akash A. Shah, Amitabh Sharma, Yun Shen, Kerstin Spirohn, Stanley Tam, Alexander O. Tejeda, Shelly A. Wanamaker, Jean-Claude Twizere, Kerwin Vega, Jennifer Walsh, Michael E. Cusick, Yu Xia, Albert-László Barabási, Lilia M. Iakoucheva, Patrick Aloy, Javier De Las Rivas, Jan Tavernier, Michael A. Calderwood, David E. Hill, Tong Hao, Frederick P. Roth, Marc Vidal

Cell. Author manuscript; available in PMC 2015 Nov 20.

Published in final edited form as: Cell. 2014 Nov 20; 159(5): 1212–1226. doi: 10.1016/j.cell.2014.10.050

PMCID:: PMC4266588

Abstract Article PDF–3.1M

Select item 389475017.

KLRG1 impairs CD4⁺ T cell responses via p16^ink4a and p27^kip1 pathways - Role in hepatitis B vaccine failure in individuals with hepatitis C virus infection

Lei Shi, Jia M. Wang, Jun P. Ren, Yong Q. Cheng, Ruo S. Ying, Xiao Y. Wu, Shu M. Lin, Jeddidiah WD Griffin, Guang Y. Li, Jonathan P. Moorman, Zhi Q. Yao

J Immunol. Author manuscript; available in PMC 2015 Jan 15.

Published in final edited form as: J Immunol. 2014 Jan 15; 192(2): 649–657. Published online 2013 Dec 13. doi: 10.4049/jimmunol.1302069

PMCID:: PMC3894750

Abstract Article PDF–3.2M

Select item 380733718.

KLRG1 Negatively Regulates Natural Killer Cell Functions through the Akt Pathway in Individuals with Chronic Hepatitis C Virus Infection

Jia M. Wang, Yong Q. Cheng, Lei Shi, Ruo S. Ying, Xiao Y. Wu, Guang Y. Li, Jonathan P. Moorman, Zhi Q. Yao

J Virol. 2013 Nov; 87(21): 11626–11636. doi: 10.1128/JVI.01515-13

PMCID:: PMC3807337

Abstract Article PDF–2.1M

Select item 317805919.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 303012320.

Structure of Natural Killer Cell Receptor KLRG1 Bound to E-Cadherin Reveals Basis for MHC-Independent Missing Self Recognition

Yili Li, Maike Hofmann, Qian Wang, Leslie Teng, Lukasz K. Chlewicki, Hanspeter Pircher, Roy A Mariuzza

Immunity. Author manuscript; available in PMC 2011 Jan 28.

Published in final edited form as: Immunity. 2009 Jul 17; 31(1): 35–46. doi: 10.1016/j.immuni.2009.04.019

PMCID:: PMC3030123

Abstract Article PDF–4.5M

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