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Select item 113815321.

Protein phosphatase 4 maintains the survival of primordial follicles by regulating autophagy in oocytes

Ming-Zhe Dong, Ying-Chun Ouyang, Shi-Cai Gao, Lin-Jian Gu, Jia-Ni Guo, Si-Min Sun, Zhen-Bo Wang, Qing-Yuan Sun

Cell Death Dis. 2024 Sep; 15(9): 658. Published online 2024 Sep 8. doi: 10.1038/s41419-024-07051-4

PMCID:: PMC11381532

Abstract Article PDF–6.1M

Select item 110277932.

Ring domains are essential for GATOR2-dependent mTORC1 activation

Cong Jiang, Xiaoming Dai, Shaohui He, Hongfei Zhou, Lan Fang, Jianping Guo, Songlei Liu, Tao Zhang, Weijuan Pan, Haihong Yu, Tianmin Fu, Dali Li, Hiroyuki Inuzuka, Ping Wang, Jianru Xiao, Wenyi Wei

Mol Cell. Author manuscript; available in PMC 2024 Apr 19.

Published in final edited form as: Mol Cell. 2023 Jan 5; 83(1): 74–89.e9. Published online 2022 Dec 16. doi: 10.1016/j.molcel.2022.11.021

PMCID:: PMC11027793

Abstract Article PDF–3.0M

Select item 105896733.

Impairment of serine transport across the blood–brain barrier by deletion of Slc38a5 causes developmental delay and motor dysfunction

Inna Radzishevsky, Maali Odeh, Oded Bodner, Salman Zubedat, Lihi Shaulov, Maxim Litvak, Kayoko Esaki, Takeo Yoshikawa, Bella Agranovich, Wen-Hong Li, Alex Radzishevsky, Eyal Gottlieb, Avi Avital, Herman Wolosker

Proc Natl Acad Sci U S A. 2023 Oct 17; 120(42): e2302780120. Published online 2023 Oct 9. doi: 10.1073/pnas.2302780120

PMCID:: PMC10589673

Abstract Article PDF–6.8M

Select item 102789924.

Protein Arginine Methyltransferase 1 Ablation in Motor Neurons Causes Mitochondrial Dysfunction Leading to Age-related Motor Neuron Degeneration with Muscle Loss

Hyun-Kyung So, Hyebeen Kim, Jinwoo Lee, Chang-Lim You, Chae-Eun Yun, Hyeon-Ju Jeong, Eun-Ju Jin, Yunju Jo, Dongryeol Ryu, Gyu-Un Bae, Jong-Sun Kang

Research (Wash D C) 2023; 6: 0158. Published online 2023 Jun 19. doi: 10.34133/research.0158

PMCID:: PMC10278992

Abstract Article PDF–7.2M

Select item 100860335.

LCRMP-1 is required for spermatogenesis and stabilises spermatid F-actin organization via the PI3K-Akt pathway

Jung-Hsuan Chang, Chia-Hua Chou, Jui-Ching Wu, Keng-Mao Liao, Wei-Jia Luo, Wei-Lun Hsu, Xuan-Ren Chen, Sung-Liang Yu, Szu-Hua Pan, Pan-Chyr Yang, Kang-Yi Su

Commun Biol. 2023; 6: 389. Published online 2023 Apr 10. doi: 10.1038/s42003-023-04778-2

PMCID:: PMC10086033

Abstract Article PDF–5.9M

Select item 98919566.

Activation of eIF4E‐binding‐protein‐1 rescues mTORC1‐induced sarcopenia by expanding lysosomal degradation capacity

Elisa M. Crombie, Seonyoung Kim, Stuart Adamson, Han Dong, Tzu‐Chiao Lu, Yiju Wu, Yajun Wu, Yotam Levy, Nolan Stimple, Wing Moon R. Lam, Hwee Weng D. Hey, Dominic J. Withers, Ao‐Lin Hsu, Boon Huat Bay, Julien Ochala, Shih‐Yin Tsai

J Cachexia Sarcopenia Muscle. 2023 Feb; 14(1): 198–213. Published online 2022 Nov 17. doi: 10.1002/jcsm.13121

PMCID:: PMC9891956

Abstract Article PDF–4.2M

Select item 97581777.

Muscle 4EBP1 activation modifies the structure and function of the neuromuscular junction in mice

Seok-Ting J. Ang, Elisa M. Crombie, Han Dong, Kuan-Ting Tan, Adriel Hernando, Dejie Yu, Stuart Adamson, Seonyoung Kim, Dominic J. Withers, Hua Huang, Shih-Yin Tsai

Nat Commun. 2022; 13: 7792. Published online 2022 Dec 17. doi: 10.1038/s41467-022-35547-0

PMCID:: PMC9758177

Abstract Article PDF–11M

Select item 95483778.

Collagen VI deficiency causes behavioral abnormalities and cortical dopaminergic dysfunction

Ilaria Gregorio, Maddalena Mereu, Gabriella Contarini, Luca Bello, Claudio Semplicini, Francesca Burgio, Loris Russo, Stefania Sut, Stefano Dall'Acqua, Paola Braghetta, Carlo Semenza, Elena Pegoraro, Francesco Papaleo, Paolo Bonaldo, Matilde Cescon

Dis Model Mech. 2022 Sep 1; 15(9): dmm049481. Published online 2022 Sep 21. doi: 10.1242/dmm.049481

PMCID:: PMC9548377

Abstract Article

Select item 92074139.

The Effects of Maternal Intake of EPA and DHA Enriched Diet During Pregnancy and Lactation on Offspring’s Muscle Development and Energy Homeostasis

Saeed Ghnaimawi, Shilei Zhang, Jamie I. Baum, Yan Huang

Front Physiol. 2022; 13: 881624. Published online 2022 Jun 6. doi: 10.3389/fphys.2022.881624

PMCID:: PMC9207413

Abstract Article PDF–6.0M

Select item 916923110.

A role for translational regulation by S6 kinase and a downstream target in inflammatory pain

June Bryan de la Peña, Nikesh Kunder, Tzu-Fang Lou, Rebecca Chase, Alexander Stanowick, Paulino Barragan-Iglesias, Joseph J. Pancrazio, Zachary T. Campbell

Br J Pharmacol. Author manuscript; available in PMC 2022 Dec 1.

Published in final edited form as: Br J Pharmacol. 2021 Dec; 178(23): 4675–4690. Published online 2021 Sep 12. doi: 10.1111/bph.15646

PMCID:: PMC9169231

Abstract Article PDF–2.2M

Select item 913740511.

Tsc1 Haploinsufficiency Leads to Pax2 Dysregulation in the Developing Murine Cerebellum

Ines Serra, Ana Stravs, Catarina Osório, Maria Roa Oyaga, Martijn Schonewille, Christian Tudorache, Aleksandra Badura

Front Mol Neurosci. 2022; 15: 831687. Published online 2022 May 13. doi: 10.3389/fnmol.2022.831687

PMCID:: PMC9137405

Abstract Article PDF–4.0M

Select item 897998812.

S6K1 controls adiponectin expression by inducing a transcriptional switch: BMAL1-to-EZH2

Sang Ah Yi, Ye Ji Jeon, Min Gyu Lee, Ki Hong Nam, Sora Ann, Jaecheol Lee, Jeung-Whan Han

Exp Mol Med. 2022 Mar; 54(3): 324–333. Published online 2022 Mar 25. doi: 10.1038/s12276-022-00747-7

PMCID:: PMC8979988

Abstract Article PDF–3.9M

Select item 878413313.

GATOR2 complex–mediated amino acid signaling regulates brain myelination

Zongyan Yu, Zhiwen Yang, Guoru Ren, Yingjie Wang, Xiang Luo, Feiyan Zhu, Shouyang Yu, Lanlan Jia, Mina Chen, Paul F. Worley, Bo Xiao

Proc Natl Acad Sci U S A. 2022 Jan 18; 119(3): e2110917119. Published online 2022 Jan 12. doi: 10.1073/pnas.2110917119

PMCID:: PMC8784133

Abstract Article PDF–3.3M

Select item 861731114.

MEK-inhibitor-mediated rescue of skeletal myopathy caused by activating Hras mutation in a Costello syndrome mouse model

William E. Tidyman, Alice F. Goodwin, Yoshiko Maeda, Ophir D. Klein, Katherine A. Rauen

Dis Model Mech. 2022 Feb 1; 15(2): dmm049166. Published online 2021 Nov 19. doi: 10.1242/dmm.049166

PMCID:: PMC8617311

Abstract Article

Select item 859366415.

p70 Ribosomal Protein S6 Kinase Is a Checkpoint of Human Hepatic Stellate Cell Activation and Liver Fibrosis in Mice

Florian P. Reiter, Liangtao Ye, Andrea Ofner, Tobias S. Schiergens, Andreas Ziesch, Lydia Brandl, Najib Ben Khaled, Simon Hohenester, Ralf Wimmer, Renate Artmann, Yulong He, Serene M.L. Lee, Doris Mayr, Changhua Zhang, Alexander L. Gerbes, Julia Mayerle, Gerald Denk, Enrico N. De Toni

Cell Mol Gastroenterol Hepatol. 2022; 13(1): 95–112. Published online 2021 Sep 17. doi: 10.1016/j.jcmgh.2021.09.001

PMCID:: PMC8593664

Abstract Article PDF–8.0M

Select item 838660016.

Mice deficient in UXT exhibit retinitis pigmentosa-like features via aberrant autophagy activation

Mingyu Pan, Yue Yin, Xinxia Wang, Quanyi Wang, Lele Zhang, Haiyang Hu, Chen Wang

Autophagy. 2021; 17(8): 1873–1888. Published online 2020 Aug 2. doi: 10.1080/15548627.2020.1796015

PMCID:: PMC8386600

Abstract Article PDF–8.5M

Select item 835604117.

TLR5 Supports Development of Placental Labyrinthine Zone in Mice

Jensen H. C. Yiu, Samson W. M. Cheung, Jieling Cai, Kam-Suen Chan, Jing Chen, Lai Yee Cheong, Hau-Tak Chau, Aimin Xu, Raymond H. W. Li, Connie W. Woo

Front Cell Dev Biol. 2021; 9: 711253. Published online 2021 Jul 28. doi: 10.3389/fcell.2021.711253

PMCID:: PMC8356041

Abstract Article PDF–4.6M

Select item 834314018.

Genetic Modulation of Initial Sensitivity to Δ9-Tetrahydrocannabinol (THC) Among the BXD Family of Mice

Cory Parks, Chris M. Rogers, Pjotr Prins, Robert W. Williams, Hao Chen, Byron C. Jones, Bob M. Moore, II, Megan K. Mulligan

Front Genet. 2021; 12: 659012. Published online 2021 Jul 23. doi: 10.3389/fgene.2021.659012

PMCID:: PMC8343140

Abstract Article PDF–2.0M

Select item 831912319.

A p53-dependent translational program directs tissue-selective phenotypes in a model of ribosomopathies

Gerald C. Tiu, Craig H. Kerr, Craig M. Forester, Pallavi S. Krishnarao, Hannah D. Rosenblatt, Nitin Raj, Travis C. Lantz, Olena Zhulyn, Margot E. Bowen, Leila Shokat, Laura D. Attardi, Davide Ruggero, Maria Barna

Dev Cell. Author manuscript; available in PMC 2022 Jul 26.

Published in final edited form as: Dev Cell. 2021 Jul 26; 56(14): 2089–2102.e11. Published online 2021 Jul 8. doi: 10.1016/j.devcel.2021.06.013