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Select item 109209831.

LINC00629, a HOXB4‐downregulated long noncoding RNA, inhibits glycolysis and ovarian cancer progression by destabilizing c‐Myc

Jia Liu, Yuan Zhu, Huan Wang, Chuanchun Han, Yongpeng Wang, Ranran Tang

Cancer Sci. 2024 Mar; 115(3): 804–819. Published online 2024 Jan 5. doi: 10.1111/cas.16049

PMCID:: PMC10920983

Abstract Article PDF–7.8M

Select item 92626142.

A dual-activity topoisomerase complex regulates mRNA translation and turnover

Shuaikun Su, Yutong Xue, Alexei Sharov, Yongqing Zhang, Seung Kyu Lee, Jennifer L Martindale, Wen Li, Wai Lim Ku, Keji Zhao, Supriyo De, Weiping Shen, Payel Sen, Myriam Gorospe, Dongyi Xu, Weidong Wang

Nucleic Acids Res. 2022 Jul 8; 50(12): 7013–7033. Published online 2022 Jun 24. doi: 10.1093/nar/gkac538

PMCID:: PMC9262614

Abstract Article PDF–3.6M

Select item 81650303.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 80090484.

Impact of cytosine methylation on DNA binding specificities of human transcription factors

Yimeng Yin, Ekaterina Morgunova, Arttu Jolma, Eevi Kaasinen, Biswajyoti Sahu, Syed Khund-Sayeed, Pratyush K. Das, Teemu Kivioja, Kashyap Dave, Fan Zhong, Kazuhiro R. Nitta, Minna Taipale, Alexander Popov, Paul A. Ginno, Silvia Domcke, Jian Yan, Dirk Schübeler, Charles Vinson, Jussi Taipale

Science. Author manuscript; available in PMC 2021 Mar 30.

Published in final edited form as: Science. 2017 May 5; 356(6337): eaaj2239. doi: 10.1126/science.aaj2239

PMCID:: PMC8009048

Abstract Article PDF–2.6M

Select item 78204155.

HOXB4 inhibits the proliferation and tumorigenesis of cervical cancer cells by downregulating the activity of Wnt/β-catenin signaling pathway

Dan Lei, Wen-Ting Yang, Peng-Sheng Zheng

Cell Death Dis. 2021 Jan; 12(1): 105. Published online 2021 Jan 21. doi: 10.1038/s41419-021-03411-6

PMCID:: PMC7820415

Abstract Article PDF–4.8M

Select item 70771416.

HOXB4 promotes the malignant progression of ovarian cancer via DHDDS

Na Li, Jin-hai Gou, Jiao Xiong, Juan-juan You, Zheng-yu Li

BMC Cancer. 2020; 20: 222. Published online 2020 Mar 16. doi: 10.1186/s12885-020-06725-4

PMCID:: PMC7077141

Abstract Article PDF–6.9M

Select item 62334957.

MiR-10a and HOXB4 are overexpressed in atypical myeloproliferative neoplasms

Pierre-Yves Dumas, Olivier Mansier, Valerie Prouzet-Mauleon, Junji Koya, Arnaud Villacreces, Philippe Brunet de la Grange, Damien Luque Paz, Audrey Bidet, Jean-Max Pasquet, Vincent Praloran, Franck Salin, Mineo Kurokawa, François-Xavier Mahon, Bruno Cardinaud, Eric Lippert

BMC Cancer. 2018; 18: 1098. Published online 2018 Nov 12. doi: 10.1186/s12885-018-4993-2

PMCID:: PMC6233495

Abstract Article PDF–1.3M

Select item 49544548.

Enforced Expression of HOXB4 in Human Embryonic Stem Cells Enhances the Production of Hematopoietic Progenitors but Has No Effect on the Maturation of Red Blood Cells

Melany Jackson, Rui Ma, A. Helen Taylor, Richard A. Axton, Jennifer Easterbrook, Maria Kydonaki, Emmanuel Olivier, Lamin Marenah, Edouard G. Stanley, Andrew G. Elefanty, Joanne C. Mountford, Lesley M. Forrester

Stem Cells Transl Med. 2016 Aug; 5(8): 981–990. Published online 2016 Jun 28. doi: 10.5966/sctm.2015-0324

PMCID:: PMC4954454

Abstract Article PDF–1.7M

Select item 47501739.

HOX transcription factors are potential targets and markers in malignant mesothelioma

Richard Morgan, Guy Simpson, Sophie Gray, Cheryl Gillett, Zsuzsanna Tabi, James Spicer, Kevin J. Harrington, Hardev S. Pandha

BMC Cancer. 2016; 16: 85. Published online 2016 Feb 11. doi: 10.1186/s12885-016-2106-7

PMCID:: PMC4750173

Abstract Article PDF–1.3M

Select item 470345310.

Activation of OCT4 enhances ex vivo expansion of human cord blood hematopoietic stem and progenitor cells by regulating HOXB4 expression

Xinxin Huang, Man-Ryul Lee, Scott Cooper, Giao Hangoc, Ki-Sung Hong, Hyung-Min Chung, Hal E. Broxmeyer

Leukemia. Author manuscript; available in PMC 2016 May 18.

Published in final edited form as: Leukemia. 2016 Jan; 30(1): 144–153. Published online 2015 Jul 23. doi: 10.1038/leu.2015.189

PMCID:: PMC4703453

Abstract Article PDF–681K

Select item 462303611.

Identification of differentially methylated markers among cytogenetic risk groups of acute myeloid leukemia

Xiaoyu Qu, Jerry Davison, Liping Du, Barry Storer, Derek L Stirewalt, Shelly Heimfeld, Elihu Estey, Frederick R Appelbaum, Min Fang

Epigenetics. 2015 Jun; 10(6): 526–535. Published online 2015 May 21. doi: 10.1080/15592294.2015.1048060

PMCID:: PMC4623036

Abstract Article PDF–637K

Select item 459893912.

HOXA4 Provides Stronger Engraftment Potential to Short-Term Repopulating Cells Than HOXB4

Marilaine Fournier, Charles-Étienne Lebert-Ghali, Janetta J. Bijl

Stem Cells Dev. 2015 Oct 15; 24(20): 2413–2422. Published online 2015 Jul 13. doi: 10.1089/scd.2015.0063

PMCID:: PMC4598939

Abstract Article PDF–581K

Select item 345440913.

Gene Expression Profiling Identifies HOXB4 as a Direct Downstream Target of GATA-2 in Human CD34+ Hematopoietic Cells

Tohru Fujiwara, Hisayuki Yokoyama, Yoko Okitsu, Mayumi Kamata, Noriko Fukuhara, Yasushi Onishi, Shinichi Fujimaki, Shinichiro Takahashi, Kenichi Ishizawa, Emery H. Bresnick, Hideo Harigae

PLoS One. 2012; 7(9): e40959. Published online 2012 Sep 24. doi: 10.1371/journal.pone.0040959

PMCID:: PMC3454409

Abstract Article PDF–614K

Select item 338466314.

The HOXB4 Homeoprotein Promotes the Ex Vivo Enrichment of Functional Human Embryonic Stem Cell-Derived NK Cells

Aniya Larbi, Jean-Marc Gombert, Céline Auvray, Bruno l’Homme, Aurélie Magniez, Olivier Féraud, Laure Coulombel, Alain Chapel, Maria Teresa Mitjavila-Garcia, Ali G. Turhan, Rima Haddad, Annelise Bennaceur-Griscelli

PLoS One. 2012; 7(6): e39514. Published online 2012 Jun 27. doi: 10.1371/journal.pone.0039514

PMCID:: PMC3384663

Abstract Article PDF–2.7M

Select item 336237115.

Dynamic HoxB4-regulatory network during embryonic stem cell differentiation to hematopoietic cells

Rong Fan, Sabrina Bonde, Peng Gao, Brendan Sotomayor, Changya Chen, Tyler Mouw, Nicholas Zavazava, Kai Tan

Blood. 2012 May 10; 119(19): e139–e147. Prepublished online 2012 Mar 21. doi: 10.1182/blood-2011-12-396754

PMCID:: PMC3362371

Abstract Article

Select item 326947316.

HOXC4 homeoprotein efficiently expands human hematopoietic stem cells and triggers similar molecular alterations as HOXB4

Céline Auvray, Andrée Delahaye, Françoise Pflumio, Rima Haddad, Sophie Amsellem, Ayda Miri-Nezhad, Loïc Broix, Azzedine Yacia, Frédérique Bulle, Serge Fichelson, Isabelle Vigon

Haematologica. 2012 Feb; 97(2): 168–178. doi: 10.3324/haematol.2011.051235

PMCID:: PMC3269473

Abstract Article PDF–1.6M

Select item 317805917.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 300310118.

Hoxb4 transduction down-regulates Geminin protein, providing hematopoietic stem and progenitor cells with proliferation potential

Yoshinori Ohno, Shin'ichiro Yasunaga, Motoaki Ohtsubo, Sayaka Mori, Miyuki Tsumura, Satoshi Okada, Tomohiko Ohta, Kiyoshi Ohtani, Masao Kobayashi, Yoshihiro Takihara

Proc Natl Acad Sci U S A. 2010 Dec 14; 107(50): 21529–21534. Published online 2010 Nov 22. doi: 10.1073/pnas.1011054107

PMCID:: PMC3003101

Abstract Article PDF–1.0M

Select item 292117419.

Effect of increased HoxB4 on human megakaryocytic development

Yiming Zhong, Brent Sullenbarger, Larry C. Lasky

Biochem Biophys Res Commun. Author manuscript; available in PMC 2011 Jul 30.

Published in final edited form as: Biochem Biophys Res Commun. 2010 Jul 30; 398(3): 377–382. Published online 2010 Jun 22. doi: 10.1016/j.bbrc.2010.06.075

PMCID:: PMC2921174

Abstract Article PDF–598K

Select item 277421820.

Generation of mesenchymal stromal cells from a HOXB4-expressing human embryonic stem cells colony

Yi-Ping Liu, Peiman Hematti

Cytotherapy. Author manuscript; available in PMC 2010 Jan 1.

Published in final edited form as: Cytotherapy. 2009; 11(6): 716–725. doi: 10.3109/14653240903051566

PMCID:: PMC2774218

Abstract Article PDF–3.7M

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