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Select item 112714081.

METTL3-mediated N⁶-methyladenosine modification of STAT5A promotes gastric cancer progression by regulating KLF4

Yichen Zang, Zhuangfei Tian, Dandan Wang, Yaxuan Li, Wenhui Zhang, Cunying Ma, Zhenzhi Liao, Wenrong Gao, Lilin Qian, Xia Xu, Jihui Jia, Zhifang Liu

Oncogene. 2024; 43(30): 2338–2354. Published online 2024 Jun 15. doi: 10.1038/s41388-024-03085-2

PMCID:: PMC11271408

Abstract Article PDF–7.9M

Select item 112409422.

KLF4 Suppresses the Progression of Hepatocellular Carcinoma by Reducing Tumor ATP Synthesis through Targeting the Mir-206/RICTOR Axis

Yongjin Wang, Dinglan Zuo, Zhenkun Huang, Yuxiong Qiu, Zongfeng Wu, Shaoru Liu, Yi Zeng, Zhiyu Qiu, Wei He, Binkui Li, Yunfei Yuan, Yi Niu, Jiliang Qiu

Int J Mol Sci. 2024 Jul; 25(13): 7165. Published online 2024 Jun 28. doi: 10.3390/ijms25137165

PMCID:: PMC11240942

Abstract Article PDF–5.2M

Select item 111599253.

Persistent Krüppel‐like factor 4 expression predicts progression and poor prognosis of head and neck squamous cell carcinoma

Shyh‐Kuan Tai, Muh‐Hwa Yang, Shyue‐Yih Chang, Yung‐Chi Chang, Wing‐Yin Li, Tung‐Lung Tsai, Yi‐Fen Wang, Pen‐Yuan Chu, Shie‐Liang Hsieh

Cancer Sci. 2011 Apr; 102(4): 895–902. Published online 2011 Mar 4. doi: 10.1111/j.1349-7006.2011.01859.x

PMCID:: PMC11159925

Abstract Article PDF–469K

Select item 109815244.

Endothelium-specific SIRT7 targeting ameliorates pulmonary hypertension through Krüpple-like factor 4 deacetylation

Jin Zhang, Chenzhong Xu, Xiaolong Tang, Shimin Sun, Siqi Liu, Langmei Yang, Yuqin Chen, Qifeng Yang, Tong-You Wade Wei, Xiaojing Wu, Jian Wang, Chen Wang, Xiaosong Yan, Lei Yang, Yanqin Niu, Deming Gou, John Y J Shyy, Baohua Liu

Cardiovasc Res. 2024 Mar; 120(4): 403–416. Published online 2024 Jan 10. doi: 10.1093/cvr/cvae011

PMCID:: PMC10981524

Abstract Article PDF–1.8M

Select item 109662645.

LncRNA SNHG1 alleviates myocardial ischaemia–reperfusion injury by regulating the miR‐137‐3p/KLF4/TRPV1 axis

Ruo‐Fu Tang, Wen‐Jing Li, Yun Lu, Xuan‐Xuan Wang, Su‐Yu Gao

ESC Heart Fail. 2024 Apr; 11(2): 1009–1021. Published online 2024 Jan 17. doi: 10.1002/ehf2.14660

PMCID:: PMC10966264

Abstract Article PDF–4.4M

Select item 108982046.

KLF4 interacts with TXNIP to modulate the pyroptosis in ulcerative colitis via regulating NLRP3 signaling

Yuan Chen, Lifeng Sun, Haiyan Liu, Jiamei Li, Lu Guo, Zhiyi Wang

Immun Inflamm Dis. 2024 Feb; 12(2): e1199. Published online 2024 Feb 27. doi: 10.1002/iid3.1199

PMCID:: PMC10898204

Abstract Article PDF–1.8M

Select item 106956057.

Expression and Functional Analysis of core stemness factors OSKM (OCT4, SOX2, KLF4, and MYC) in Pan-cancer

Liwei Hong, Sijie Hong, Xueqin Zhang

Medicine (Baltimore) 2023 Dec 1; 102(48): e36433. Published online 2023 Dec 1. doi: 10.1097/MD.0000000000036433

PMCID:: PMC10695605

Abstract Article PDF–3.6M

Select item 106522408.

KLF4 suppresses the proliferation of perihilar cholangiocarcinoma by negatively regulating GDF15 and phosphorylating AKT

Xiaoming Zhang, Weijia Wang, Chunlei Lu, Haifeng Zhang

Oncol Rep. 2023 Dec; 50(6): 222. Published online 2023 Nov 6. doi: 10.3892/or.2023.8659

PMCID:: PMC10652240

Abstract Article PDF–7.4M

Select item 105323279.

EGR1 Regulation of Vasculogenic Mimicry in the MDA-MB-231 Triple-Negative Breast Cancer Cell Line through the Upregulation of KLF4 Expression

Euitaek Jung, Young Han Lee, Sukjin Ou, Tae Yoon Kim, Soon Young Shin

Int J Mol Sci. 2023 Sep; 24(18): 14375. Published online 2023 Sep 21. doi: 10.3390/ijms241814375

PMCID:: PMC10532327

Abstract Article PDF–4.2M

Select item 1053097210.

Overexpression of KLF4 Suppresses Pulmonary Fibrosis through the HIF-1α/Endoplasmic Reticulum Stress Signaling Pathway

Shanchen Wei, Fei Qi, Yanping Wu, Xinmin Liu

Int J Mol Sci. 2023 Sep; 24(18): 14008. Published online 2023 Sep 12. doi: 10.3390/ijms241814008

PMCID:: PMC10530972

Abstract Article PDF–2.2M

Select item 1037356811.

Transcription factor Krüppel‐like factor 4 upregulated G protein‐coupled receptor 30 alleviates intestinal inflammation and apoptosis, and protects intestinal integrity from intestinal ischemia–reperfusion injury

Jie Yin, Xiaoli Xie, Jinfeng Yao, Xiaoxu Jin, Huiqing Jiang, Chenguang Ji

Immun Inflamm Dis. 2023 Jul; 11(7): e940. Published online 2023 Jul 27. doi: 10.1002/iid3.940

PMCID:: PMC10373568

Abstract Article PDF–3.8M

Select item 1031585312.

SNHG1, a KLF4‐upregulated gene, promotes glioma cell survival and tumorigenesis under endoplasmic reticulum stress by upregulating BIRC3 expression

Hongqiang Zhang, Binbin Ma, Na Li, Li Zhang, Jialu Xu, Shuqi Zhang, Ziming Guo, Chuanchun Han, Shasha Xu, Xiaodong Li, Bo Zhang

J Cell Mol Med. 2023 Jul; 27(13): 1806–1819. Published online 2023 May 26. doi: 10.1111/jcmm.17779

PMCID:: PMC10315853

Abstract Article PDF–13M

Select item 1023661213.

MED27 plays a tumor‐promoting role in breast cancer progression by targeting KLF4

Ruozhu Wang, Wendan Yu, Tianhua Zhu, Fei Lin, Chunyu Hua, Liyuan Ru, Ping Guo, Xinyu Wan, Guoqing Xue, Ziyue Guo, Shilong Han, Kuan Lv, Guohui Zhang, Hanxiao Ge, Wei Guo, Lingzhi Xu, Wuguo Deng

Cancer Sci. 2023 Jun; 114(6): 2277–2292. Published online 2023 Mar 1. doi: 10.1111/cas.15757

PMCID:: PMC10236612

Abstract Article PDF–29M

Select item 1019174314.

Gene Signatures and Associated Transcription Factors of Allergic Rhinitis: KLF4 Expression Is Associated with Immune Response

Youngsic Jeon, Tae Kyeom Kang, Wook-Bin Lee, Sang Hoon Jung, Young-Joo Kim

Biomed Res Int. 2023; 2023: 1317998. Published online 2023 May 10. doi: 10.1155/2023/1317998

PMCID:: PMC10191743

Abstract Article PDF–2.7M

Select item 992371515.

In vitro conversion of adult murine endothelial cells to haematopoietic stem cells

José Gabriel Barcia Durán, Raphaël Lis, Tyler M. Lu, Shahin Rafii

Nat Protoc. Author manuscript; available in PMC 2023 Feb 13.

Published in final edited form as: Nat Protoc. 2018 Dec; 13(12): 2758–2780. doi: 10.1038/s41596-018-0060-3

PMCID:: PMC9923715

Abstract Article PDF–1.8M

Select item 979798816.

TBK1 posphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1

Jianwen Zhou, Nikoline Lander Rasmussen, Hallvard Lauritz Olsvik, Vyacheslav Akimov, Zehan Hu, Gry Evjen, Stéphanie Kaeser-Pebernard, Devanarayanan Siva Sankar, Carole Roubaty, Pauline Verlhac, Nicole van de Beek, Fulvio Reggiori, Yakubu Princely Abudu, Blagoy Blagoev, Trond Lamark, Terje Johansen, Jörn Dengjel

J Cell Biol. 2023 Feb 6; 222(2): e202108144. Published online 2022 Dec 27. doi: 10.1083/jcb.202108144

PMCID:: PMC9797988

Abstract Article PDF–6.9M

Select item 976473017.

LINC00629 protects osteosarcoma cell from ER stress-induced apoptosis and facilitates tumour progression by elevating KLF4 stability

Yuan Wang, Shuo Zheng, Jian Han, Na Li, Renchen Ji, Xiaodong Li, Chuanchun Han, Wenzhi Zhao, Lu Zhang

J Exp Clin Cancer Res. 2022; 41: 354. Published online 2022 Dec 20. doi: 10.1186/s13046-022-02569-x

PMCID:: PMC9764730

Abstract Article PDF–13M

Select item 972267018.

KLF4-PFKFB3-driven glycolysis is essential for phenotypic switching of vascular smooth muscle cells

Xinhua Zhang, Bin Zheng, Lingdan Zhao, Jiayi Shen, Zhan Yang, Yu Zhang, Ruirui Fan, Manli Zhang, Dong Ma, Lemin Zheng, Mingming Zhao, Huirong Liu, Jinkun Wen

Commun Biol. 2022; 5: 1332. Published online 2022 Dec 5. doi: 10.1038/s42003-022-04302-y

PMCID:: PMC9722670

Abstract Article PDF–4.4M

Select item 969968119.

Krüppel-like factor 4 regulates the cytolytic effector function of exhausted CD8 T cells

Jinwoo Nah, Rho H. Seong

Sci Adv. 2022 Nov; 8(47): eadc9346. Published online 2022 Nov 25. doi: 10.1126/sciadv.adc9346

PMCID:: PMC9699681

Abstract Article PDF–2.6M

Select item 955254720.

miR-200c-SUMOylated KLF4 feedback loop acts as a switch in transcriptional programs that control VSMC proliferation

Bin Zheng, Michel Bernier, Xin-hua Zhang, Toru Suzuki, Chan-quan Nie, Yong hui Li, Yong Zhang, Li-li Song, Hui-jing Shi, Yan Liu, Cui-ying Zheng, Jin-kun Wen

J Mol Cell Cardiol. Author manuscript; available in PMC 2022 Oct 11.

Published in final edited form as: J Mol Cell Cardiol. 2015 May; 82: 201–212. Published online 2015 Mar 17. doi: 10.1016/j.yjmcc.2015.03.011