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Items: 1 to 20 of 32

1.
HSF1 phosphorylation establishes an active chromatin state via the TRRAP–TIP60 complex and promotes tumorigenesis
Mitsuaki Fujimoto, Ryosuke Takii, Masaki Matsumoto, Mariko Okada, Keiich I. Nakayama, Ryuichiro Nakato, Katsunori Fujiki, Katsuhiko Shirahige, Akira Nakai
Nat Commun. 2022; 13: 4355. Published online 2022 Jul 29. doi: 10.1038/s41467-022-32034-4
PMCID:
PMC9338313
AbstractArticlePDF–2.8M
2.
A dual-activity topoisomerase complex regulates mRNA translation and turnover
Shuaikun Su, Yutong Xue, Alexei Sharov, Yongqing Zhang, Seung Kyu Lee, Jennifer L Martindale, Wen Li, Wai Lim Ku, Keji Zhao, Supriyo De, Weiping Shen, Payel Sen, Myriam Gorospe, Dongyi Xu, Weidong Wang
Nucleic Acids Res. 2022 Jul 8; 50(12): 7013–7033. Published online 2022 Jun 24. doi: 10.1093/nar/gkac538
PMCID:
PMC9262614
AbstractArticlePDF–3.6M
3.
Regional heritability mapping identifies several novel loci (STAT4, ULK4, and KCNH5) for primary biliary cholangitis in the Japanese population
Olivier Gervais, Kazuko Ueno, Yosuke Kawai, Yuki Hitomi, Yoshihiro Aiba, Mayumi Ueta, Minoru Nakamura, Katsushi Tokunaga, Masao Nagasaki
Eur J Hum Genet. 2021 Aug; 29(8): 1282–1291. Published online 2021 Apr 9. doi: 10.1038/s41431-021-00854-5
PMCID:
PMC8385030
AbstractArticlePDF–952K
4.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
5.
Kinase Interaction Network Expands Functional and Disease Roles of Human Kinases
Marija Buljan, Rodolfo Ciuffa, Audrey van Drogen, Anton Vichalkovski, Martin Mehnert, George Rosenberger, Sohyon Lee, Markku Varjosalo, Lucia Espona Pernas, Vincent Spegg, Berend Snijder, Ruedi Aebersold, Matthias Gstaiger
Mol Cell. 2020 Aug 6; 79(3): 504–520.e9. doi: 10.1016/j.molcel.2020.07.001
PMCID:
PMC7427327
AbstractArticle
6.
High resolution structure and inhibition of the schizophrenia-linked pseudokinase ULK4
Susmita Khamrui, Peter M.U. Ung, Cody Secor, Avner Schlessinger, Michael B. Lazarus
J Am Chem Soc. Author manuscript; available in PMC 2020 Nov 8.
Published in final edited form as: J Am Chem Soc. 2020 Jan 8; 142(1): 33–37. Published online 2019 Dec 17. doi: 10.1021/jacs.9b10458
PMCID:
PMC7261596
AbstractArticlePDF–1.0M
7.
LncRNA DUXAP9‐206 directly binds with Cbl‐b to augment EGFR signaling and promotes non‐small cell lung cancer progression
Ting Zhu, Shu An, Man‐Ting Choy, Junhao Zhou, Shanshan Wu, Shihua Liu, Bangdong Liu, Zhicheng Yao, Xun Zhu, Jueheng Wu, Zhenjian He
J Cell Mol Med. 2019 Mar; 23(3): 1852–1864. Published online 2018 Dec 4. doi: 10.1111/jcmm.14085
Correction in:
J Cell Mol Med. 2022 Apr; 26(7): 2137.
PMCID:
PMC6378200
AbstractArticlePDF–8.1M
8.
Histone Interaction Landscapes Visualized by Crosslinking Mass Spectrometry in Intact Cell Nuclei
Domenico Fasci, Hugo van Ingen, Richard A. Scheltema, Albert J. R. Heck
Mol Cell Proteomics. 2018 Oct; 17(10): 2018–2033. Published online 2018 Jul 18. doi: 10.1074/mcp.RA118.000924
PMCID:
PMC6166682
AbstractArticlePDF–3.8M
9.
VIRMA mediates preferential m6A mRNA methylation in 3′UTR and near stop codon and associates with alternative polyadenylation
Yanan Yue, Jun Liu, Xiaolong Cui, Jie Cao, Guanzheng Luo, Zezhou Zhang, Tao Cheng, Minsong Gao, Xiao Shu, Honghui Ma, Fengqin Wang, Xinxia Wang, Bin Shen, Yizhen Wang, Xinhua Feng, Chuan He, Jianzhao Liu
Cell Discov. 2018; 4: 10. Published online 2018 Feb 27. doi: 10.1038/s41421-018-0019-0
PMCID:
PMC5826926
AbstractArticlePDF–2.3M
10.
Architecture of the human interactome defines protein communities and disease networks
Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper
Nature. Author manuscript; available in PMC 2017 Nov 17.
Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366
PMCID:
PMC5531611
AbstractArticlePDF–2.7M
11.
Common variation at 3p22.1 and 7p15.3 influences multiple myeloma risk
Peter Broderick, Daniel Chubb, David C Johnson, Niels Weinhold, Asta Försti, Amy Lloyd, Bianca Olver, Yussanne Ma, Sara E Dobbins, Brian A Walker, Faith E Davies, Walter A Gregory, J. Anthony Childs, Fiona M Ross, Graham H Jackson, Kai Neben, Anna Jauch, Per Hoffmann, Thomas W Mühleisen, Markus M Nöthen, Susanne Moebus, Ian P Tomlinson, Hartmut Goldschmidt, Kari Hemminki, Gareth J Morgan, Richard S Houlston
Nat Genet. Author manuscript; available in PMC 2016 Nov 14.
Published in final edited form as: Nat Genet. 2011 Nov 27; 44(1): 58–61. Published online 2011 Nov 27. doi: 10.1038/ng.993
PMCID:
PMC5108406
AbstractArticlePDF–663K
12.
The CCND1 870G>A polymorphism is a risk factor for t(11;14)(q13;q32) multiple myeloma
Niels Weinhold, David C Johnson, Daniel Chubb, Bowang Chen, Asta Försti, Fay J Hosking, Peter Broderick, Yussanne P Ma, Sara E Dobbins, Dirk Hose, Brian A Walker, Faith E Davies, Martin F Kaiser, Ni L Li, Walter A Gregory, Graham H Jackson, Mathias Witzens-Harig, Kai Neben, Per Hoffmann, Markus M Nöthen, Thomas W Mühleisen, Lewin Eisele, Fiona M Ross, Anna Jauch, Hartmut Goldschmidt, Richard S Houlston, Gareth J Morgan, Kari Hemminki
Nat Genet. Author manuscript; available in PMC 2016 Oct 10.
Published in final edited form as: Nat Genet. 2013 May; 45(5): 522–525. Published online 2013 Mar 17. doi: 10.1038/ng.2583
PMCID:
PMC5056630
AbstractArticlePDF–483K
13.
Genetic Variants in LRP1 and ULK4 Are Associated with Acute Aortic Dissections
Dong-chuan Guo, Megan L. Grove, Siddharth K. Prakash, Per Eriksson, Ellen M. Hostetler, Scott A. LeMaire, Simon C. Body, Sherene Shalhub, Anthony L. Estrera, Hazim J. Safi, Ellen S. Regalado, Wei Zhou, Michael R. Mathis, GenTAC Investigators, BAVCon Investigators, Kim A. Eagle, Bo Yang, Cristen J. Willer, Eric Boerwinkle, Dianna M. Milewicz
Am J Hum Genet. 2016 Sep 1; 99(3): 762–769. Published online 2016 Aug 25. doi: 10.1016/j.ajhg.2016.06.034
PMCID:
PMC5011062
AbstractArticlePDF–979K
14.
Survival kinase genes present prognostic significance in glioblastoma
Robin T. Varghese, Yanping Liang, Ting Guan, Christopher T. Franck, Deborah F. Kelly, Zhi Sheng
Oncotarget. 2016 Apr 12; 7(15): 20140–20151. Published online 2016 Mar 4. doi: 10.18632/oncotarget.7917
PMCID:
PMC4991443
AbstractArticlePDF–9.5M
15.
Cross-cancer profiling of molecular alterations within the human autophagy interaction network
Chandra B Lebovitz, A Gordon Robertson, Rodrigo Goya, Steven J Jones, Ryan D Morin, Marco A Marra, Sharon M Gorski
Autophagy. 2015 Sep; 11(9): 1668–1687. Published online 2015 Jul 24. doi: 10.1080/15548627.2015.1067362
PMCID:
PMC4590660
AbstractArticlePDF–1.8M
16.
Genome-wide association study in Chinese identifies novel loci for blood pressure and hypertension
Xiangfeng Lu, Laiyuan Wang, Xu Lin, Jianfeng Huang, C. Charles Gu, Meian He, Hongbing Shen, Jiang He, Jingwen Zhu, Huaixing Li, James E. Hixson, Tangchun Wu, Juncheng Dai, Ling Lu, Chong Shen, Shufeng Chen, Lin He, Zengnan Mo, Yongchen Hao, Xingbo Mo, Xueli Yang, Jianxin Li, Jie Cao, Jichun Chen, Zhongjie Fan, Ying Li, Liancheng Zhao, Hongfan Li, Fanghong Lu, Cailiang Yao, Lin Yu, Lihua Xu, Jianjun Mu, Xianping Wu, Ying Deng, Dongsheng Hu, Weidong Zhang, Xu Ji, Dongshuang Guo, Zhirong Guo, Zhengyuan Zhou, Zili Yang, Renping Wang, Jun Yang, Xiaoyang Zhou, Weili Yan, Ningling Sun, Pingjin Gao, Dongfeng Gu
Hum Mol Genet. 2015 Feb 1; 24(3): 865–874. Published online 2014 Sep 23. doi: 10.1093/hmg/ddu478
PMCID:
PMC4303798
AbstractArticlePDF–408K
17.
Haplotype approach for association analysis on hypertension
Xiaowei Shen, Osvaldo Espin-Garcia, Xin Qiu, Yonathan Brhane, Geoffrey Liu, Wei Xu
BMC Proc. 2014; 8(Suppl 1): S57. Published online 2014 Jun 17. doi: 10.1186/1753-6561-8-S1-S57
PMCID:
PMC4143719
AbstractArticlePDF–457K
18.
Bivariate genetic association analysis of systolic and diastolic blood pressure by copula models
Stefan Konigorski, Yildiz E Yilmaz, Shelley B Bull
BMC Proc. 2014; 8(Suppl 1): S72. Published online 2014 Jun 17. doi: 10.1186/1753-6561-8-S1-S72
PMCID:
PMC4143670
AbstractArticlePDF–531K
19.
Elevated blood pressure: Our family’s fault? The genetics of essential hypertension
Aniket Natekar, Randi L Olds, Meghann W Lau, Kathleen Min, Karra Imoto, Thomas P Slavin
World J Cardiol. 2014 May 26; 6(5): 327–337. Published online 2014 May 26. doi: 10.4330/wjc.v6.i5.327
PMCID:
PMC4062117
AbstractArticlePDF–885K
20.
The phosphorylation of HIV-1 Gag by atypical protein kinase C facilitates viral infectivity by promoting Vpr incorporation into virions
Ayumi Kudoh, Shoukichi Takahama, Tatsuya Sawasaki, Hirotaka Ode, Masaru Yokoyama, Akiko Okayama, Akiyo Ishikawa, Kei Miyakawa, Satoko Matsunaga, Hirokazu Kimura, Wataru Sugiura, Hironori Sato, Hisashi Hirano, Shigeo Ohno, Naoki Yamamoto, Akihide Ryo
Retrovirology. 2014; 11: 9. Published online 2014 Jan 22. doi: 10.1186/1742-4690-11-9
PMCID:
PMC3905668
AbstractArticlePDF–3.6M

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