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Items: 1 to 20 of 114

1.
Unraveling the Oncogenic Potential of VAV1 in Human Cancer: Lessons from Mouse Models
Batel Shalom, Yaser Salaymeh, Matan Risling, Shulamit Katzav
Cells. 2023 May; 12(9): 1276. Published online 2023 Apr 27. doi: 10.3390/cells12091276
PMCID:
PMC10177506
AbstractArticlePDF–2.5M
2.
RhoA G17E/Vav1 Signaling Induces Cancer Invasion via Matrix Metalloproteinase-9 in Gastric Cancer
Satoshi Nakamura, Masato Kitazawa, Yusuke Miyagawa, Makoto Koyama, Satoru Miyazaki, Nao Hondo, Futoshi Muranaka, Shigeo Tokumaru, Yuta Yamamoto, Takehito Ehara, Tomio Matsumura, Michiko Takeoka, Yuji Soejima
Technol Cancer Res Treat. 2023; 22: 15330338221146024. Published online 2023 Jan 9. doi: 10.1177/15330338221146024
PMCID:
PMC9834417
AbstractArticlePDF–5.8M
3.
Spatially resolved in silico modeling of NKG2D signaling kinetics suggests a key role of NKG2D and Vav1 Co-clustering in generating natural killer cell activation
Rajdeep Kaur Grewal, Jayajit Das
PLoS Comput Biol. 2022 May; 18(5): e1010114. Published online 2022 May 18. doi: 10.1371/journal.pcbi.1010114
PMCID:
PMC9154193
AbstractArticlePDF–2.4M
4.
Vav1 Promotes B-Cell Lymphoma Development
Batel Shalom, Marganit Farago, Yaser Salaymeh, Shulamit Sebban, Eli Pikarsky, Shulamit Katzav
Cells. 2022 Mar; 11(6): 949. Published online 2022 Mar 10. doi: 10.3390/cells11060949
PMCID:
PMC8946024
AbstractArticlePDF–5.5M
5.
Identification of molecular subtyping system and four-gene prognostic signature with immune-related genes for uveal melanoma
Fei Xia, Zhilong Yu, Aijun Deng, Guohong Gao
Exp Biol Med (Maywood) 2022 Feb; 247(3): 246–262. Published online 2021 Nov 7. doi: 10.1177/15353702211053801
PMCID:
PMC8851532
AbstractArticlePDF–3.9M
6.
CFTR interactome mapping using the mammalian membrane two‐hybrid high‐throughput screening system
Sang Hyun Lim, Jamie Snider, Liron Birimberg‐Schwartz, Wan Ip, Joana C Serralha, Hugo M Botelho, Miquéias Lopes‐Pacheco, Madalena C Pinto, Mohamed Taha Moutaoufik, Mara Zilocchi, Onofrio Laselva, Mohsen Esmaeili, Max Kotlyar, Anna Lyakisheva, Priscilla Tang, Lucía López Vázquez, Indira Akula, Farzaneh Aboualizadeh, Victoria Wong, Ingrid Grozavu, Teuta Opacak‐Bernardi, Zhong Yao, Meg Mendoza, Mohan Babu, Igor Jurisica, Tanja Gonska, Christine E Bear, Margarida D Amaral, Igor Stagljar
Mol Syst Biol. 2022 Feb; 18(2): e10629. Published online 2022 Feb 14. doi: 10.15252/msb.202110629
PMCID:
PMC8842165
AbstractArticlePDF–3.0M
7.
Cancer‐associated mutations in VAV1 trigger variegated signaling outputs and T‐cell lymphomagenesis
Javier Robles‐Valero, Lucía Fernández‐Nevado, L Francisco Lorenzo‐Martín, Myriam Cuadrado, Isabel Fernández‐Pisonero, Sonia Rodríguez‐Fdez, Elsa N Astorga‐Simón, Antonio Abad, Rubén Caloto, Xosé R Bustelo
EMBO J. 2021 Nov 15; 40(22): e108125. Published online 2021 Oct 7. doi: 10.15252/embj.2021108125
PMCID:
PMC8591544
AbstractArticlePDF–4.9M
8.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
9.
A novel p53 regulator, C16ORF72/TAPR1, buffers against telomerase inhibition
Yahya Benslimane, María Sánchez‐Osuna, Jasmin Coulombe‐Huntington, Thierry Bertomeu, Danielle Henry, Caroline Huard, Éric Bonneil, Pierre Thibault, Mike Tyers, Lea Harrington
Aging Cell. 2021 Apr; 20(4): e13331. Published online 2021 Mar 4. doi: 10.1111/acel.13331
PMCID:
PMC8045932
AbstractArticlePDF–1.9M
10.
Vav1 Sustains the In Vitro Differentiation of Normal and Tumor Precursors to Insulin Producing Cells Induced by all-Trans Retinoic Acid (ATRA)
Federica Brugnoli, Silvia Grassilli, Vincenzo Cardinale, Guido Carpino, Eugenio Gaudio, Domenico Alvaro, Silvano Capitani, Valeria Bertagnolo
Stem Cell Rev Rep. 2021; 17(2): 673–684. Published online 2020 Nov 9. doi: 10.1007/s12015-020-10074-x
PMCID:
PMC8036226
AbstractArticlePDF–5.3M
11.
New insights into the Vav1 activation cycle in lymphocytes
María Barreira, Sonia Rodríguez-Fdez, Xosé R. Bustelo
Cell Signal. Author manuscript; available in PMC 2024 Mar 13.
Published in final edited form as: Cell Signal. 2018 May 1; 45: 132–144. Published online 2018 Feb 2. doi: 10.1016/j.cellsig.2018.01.026
PMCID:
PMC7615736
AbstractArticlePDF–2.3M
12.
VAV1 Gene Polymorphisms in Patients with Rheumatoid Arthritis
Andrzej Pawlik, Damian Malinowski, Agnieszka Paradowska-Gorycka, Krzysztof Safranow, Violetta Dziedziejko
Int J Environ Res Public Health. 2020 May; 17(9): 3214. Published online 2020 May 5. doi: 10.3390/ijerph17093214
PMCID:
PMC7246862
AbstractArticlePDF–320K
13.
Vav1 and mutant K-Ras synergize in the early development of pancreatic ductal adenocarcinoma in mice
Yaser Salaymeh, Marganit Farago, Shulamit Sebban, Batel Shalom, Eli Pikarsky, Shulamit Katzav
Life Sci Alliance. 2020 May; 3(5): e202000661. Published online 2020 Apr 10. doi: 10.26508/lsa.202000661
PMCID:
PMC7156281
AbstractArticlePDF–2.6M
14.
NKG2D–DAP10 signaling recruits EVL to the cytotoxic synapse to generate F-actin and promote NK cell cytotoxicity
Katelynn M. Wilton, Brittany L. Overlee, Daniel D. Billadeau
J Cell Sci. 2020 Mar 1; 133(5): jcs230508. Published online 2019 Jul 18. doi: 10.1242/jcs.230508
PMCID:
PMC7055393
AbstractArticle
15.
Extensive rewiring of the EGFR network in colorectal cancer cells expressing transforming levels of KRASG13D
Susan A. Kennedy, Mohamed-Ali Jarboui, Sriganesh Srihari, Cinzia Raso, Kenneth Bryan, Layal Dernayka, Theodosia Charitou, Manuel Bernal-Llinares, Carlos Herrera-Montavez, Aleksandar Krstic, David Matallanas, Max Kotlyar, Igor Jurisica, Jasna Curak, Victoria Wong, Igor Stagljar, Thierry LeBihan, Lisa Imrie, Priyanka Pillai, Miriam A. Lynn, Erik Fasterius, Cristina Al-Khalili Szigyarto, James Breen, Christina Kiel, Luis Serrano, Nora Rauch, Oleksii Rukhlenko, Boris N. Kholodenko, Luis F. Iglesias-Martinez, Colm J. Ryan, Ruth Pilkington, Patrizia Cammareri, Owen Sansom, Steven Shave, Manfred Auer, Nicola Horn, Franziska Klose, Marius Ueffing, Karsten Boldt, David J. Lynn, Walter Kolch
Nat Commun. 2020; 11: 499. Published online 2020 Jan 24. doi: 10.1038/s41467-019-14224-9
PMCID:
PMC6981206
AbstractArticlePDF–3.7M
16.
Phosphatidylinositol Monophosphates Regulate Optimal Vav1 Signaling Output
Sonia Rodríguez-Fdez, Carmen Citterio, L. Francisco Lorenzo-Martín, Jesús Baltanás-Copado, Clara Llorente-González, Senena Corbalán-García, Miguel Vicente-Manzanares, Xosé R. Bustelo
Cells. 2019 Dec; 8(12): 1649. Published online 2019 Dec 16. doi: 10.3390/cells8121649
PMCID:
PMC6952945
AbstractArticlePDF–4.3M
17.
Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity
Jae Jin Kim, Seo Yun Lee, Fade Gong, Anna M. Battenhouse, Daniel R. Boutz, Aarti Bashyal, Samantha T. Refvik, Cheng-Ming Chiang, Blerta Xhemalce, Tanya T. Paull, Jennifer S. Brodbelt, Edward M. Marcotte, Kyle M. Miller
Genes Dev. 2019 Dec 1; 33(23-24): 1751–1774. doi: 10.1101/gad.331231.119
PMCID:
PMC6942044
AbstractArticlePDF–10M
18.
Src-dependent DBL family members drive resistance to vemurafenib in human melanoma
Charlotte R. Feddersen, Jacob L. Schillo, Afshin Varzavand, Hayley R. Vaughn, Lexy S. Wadsworth, Andrew P. Voigt, Eliot Y. Zhu, Brooke M. Jennings, Sarah A. Mullen, Jeremy Bobera, Jesse D. Riordan, Christopher S. Stipp, Adam J. Dupuy
Cancer Res. Author manuscript; available in PMC 2020 Apr 1.
Published in final edited form as: Cancer Res. 2019 Oct 1; 79(19): 5074–5087. Published online 2019 Aug 15. doi: 10.1158/0008-5472.CAN-19-0244
PMCID:
PMC6774858
AbstractArticlePDF–1.9M
19.
Activation of Rac GTPase by p75 Is Necessary for c-jun N-Terminal Kinase-Mediated Apoptosis
Anthony W. Harrington, Ju Young Kim, Sung Ok Yoon
J Neurosci. 2002 Jan 1; 22(1): 156–166. doi: 10.1523/JNEUROSCI.22-01-00156.2002
PMCID:
PMC6757583
AbstractArticlePDF–582K
20.
ATG5 is required for B cell polarization and presentation of particulate antigens
Florent Arbogast, Johan Arnold, Philippe Hammann, Lauriane Kuhn, Johana Chicher, Diane Murera, Justine Weishaar, Sylviane Muller, Jean-Daniel Fauny, Frédéric Gros
Autophagy. 2019; 15(2): 280–294. Published online 2018 Sep 22. doi: 10.1080/15548627.2018.1516327
PMCID:
PMC6333460
AbstractArticlePDF–2.7M

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