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Select item 115275281.

Genetic Variations in AMPK, FOXO3A, and POMC Increase the Risk of Extreme Obesity

Cinthia Vila Nova Santana, Luiz Alexandre Viana Magno, Adauto Versiani Ramos, Maria Angélica Rios, Valéria Cristina Sandrim, Luiz Armando De Marco, Débora Marques de Miranda, Marco Aurélio Romano-Silva

J Obes. 2024; 2024: 3813621. Published online 2024 Oct 24. doi: 10.1155/2024/3813621

PMCID:: PMC11527528

Abstract Article PDF–433K

Select item 112099352.

Antagonistic roles of canonical and alternative-RPA in disease-associated tandem CAG repeat instability

Terence Gall-Duncan, Jennifer Luo, Carla-Marie Jurkovic, Laura A. Fischer, Kyota Fujita, Amit L. Deshmukh, Rachel J. Harding, Stephanie Tran, Mustafa Mehkary, Vanessa Li, David E. Leib, Ran Chen, Hikari Tanaka, Amanda G. Mason, Dominique Lévesque, Mahreen Khan, Mortezaali Razzaghi, Tanya Prasolava, Stella Lanni, Nozomu Sato, Marie-Christine Caron, Gagan B. Panigrahi, Peixiang Wang, Rachel Lau, Arturo López Castel, Jean-Yves Masson, Lynette Tippett, Clinton Turner, Maria Spies, Albert R. La Spada, Eric I. Campos, Maurice A. Curtis, François-Michel Boisvert, Richard L.M. Faull, Beverly L. Davidson, Masayuki Nakamori, Hitoshi Okazawa, Marc S. Wold, Christopher E. Pearson

Cell. Author manuscript; available in PMC 2024 Oct 26.

Published in final edited form as: Cell. 2023 Oct 26; 186(22): 4898–4919.e25. Published online 2023 Oct 11. doi: 10.1016/j.cell.2023.09.008

PMCID:: PMC11209935

Abstract Article PDF–3.0M

Select item 111586453.

Active FKHRL1 overcomes imatinib resistance in chronic myelogenous leukemia‐derived cell lines via the production of tumor necrosis factor‐related apoptosis‐inducing ligand

Satoru Kikuchi, Tadashi Nagai, Masae Kunitama, Keita Kirito, Keiya Ozawa, Norio Komatsu

Cancer Sci. 2007 Dec; 98(12): 1949–1958. Published online 2007 Sep 26. doi: 10.1111/j.1349-7006.2007.00623.x

PMCID:: PMC11158645

Abstract Article PDF–1.0M

Select item 111137154.

A novel AMPK-dependent FoxO3A-SIRT3 intramitochondrial complex sensing glucose levels

Alessia Peserico, Fulvio Chiacchiera, Valentina Grossi, Antonio Matrone, Dominga Latorre, Marta Simonatto, Aurora Fusella, James G. Ryall, Lydia W. S. Finley, Marcia C. Haigis, Gaetano Villani, Pier Lorenzo Puri, Vittorio Sartorelli, Cristiano Simone

Cell Mol Life Sci. 2013 Jun; 70(11): 2015–2029. Published online 2013 Jan 3. doi: 10.1007/s00018-012-1244-6

PMCID:: PMC11113715

Abstract Article PDF–1.3M

Select item 111135255.

Senescence of human skin-derived precursors regulated by Akt-FOXO3-p27^KIP1/p15^INK4b signaling

Shuang Liu, Xinyue Wang, Qian Zhao, Shu Liu, Huishan Zhang, Junchao Shi, Na Li, Xiaohua Lei, Huashan Zhao, Zhili Deng, Yujing Cao, Lina Ning, Guoliang Xia, Enkui Duan

Cell Mol Life Sci. 2015 Aug; 72(15): 2949–2960. Published online 2015 Mar 10. doi: 10.1007/s00018-015-1877-3

PMCID:: PMC11113525

Abstract Article PDF–5.7M

Select item 110724196.

The forkhead box O3 (FOXO3): a key player in the regulation of ischemia and reperfusion injury

Moussa Omorou, Yiwei Huang, Meng Gao, Chenxi Mu, Weijing Xu, Yuchun Han, Hui Xu

Cell Mol Life Sci. 2023 Apr; 80(4): 102. Published online 2023 Mar 20. doi: 10.1007/s00018-023-04755-2

PMCID:: PMC11072419

Abstract Article PDF–1.6M

Select item 110317287.

FOXO3a deregulation in uterine smooth muscle tumors

Thais Gomes de Almeida, Anamaria Ritti Ricci, Laura Gonzalez dos Anjos, Jose Maria Soares Junior, Gustavo Arantes Rosa Maciel, Edmund Chada Baracat, Katia Candido Carvalho

Clinics (Sao Paulo) 2024 Jan-Dec; 79: 100350. Published online 2024 Apr 17. doi: 10.1016/j.clinsp.2024.100350

PMCID:: PMC11031728

Abstract Article PDF–4.2M

Select item 110240228.

circRNA-PTPN4 mediated regulation of FOXO3 and ZO-1 expression: implications for blood–brain barrier integrity and cognitive function in uremic encephalopathy

Yuhan Liu, Yanling Qin, Yanning Zhang

Cell Biol Toxicol. 2024; 40(1): 22. Published online 2024 Apr 17. doi: 10.1007/s10565-024-09865-6

PMCID:: PMC11024022

Abstract Article PDF–7.4M

Select item 110182059.

The role of transcription factor FOXA1/C2/M1/O3/P1/Q1 in breast cancer

Hui Yuan, Yu Liang, Shaorun Hu, Jinxiang Chen, Jingcan You, Jun Jiang, Mao Luo, Min Zeng

Medicine (Baltimore) 2024 Apr 12; 103(15): e37709. Published online 2024 Apr 12. doi: 10.1097/MD.0000000000037709

PMCID:: PMC11018205

Abstract Article PDF–3.3M

Select item 1082984810.

FoxO3 might be involved in the inflammatory response of human monocytes to lipopolysaccharide through regulating expression of toll like receptor 4

Shujun Zhang, Zhuan Li, Steven Weinman

Mol Biol Rep. Author manuscript; available in PMC 2024 Jan 31.

Published in final edited form as: Mol Biol Rep. 2022 Aug; 49(8): 7611–7621. Published online 2022 May 26. doi: 10.1007/s11033-022-07576-x

PMCID:: PMC10829848

Abstract Article PDF–999K

Select item 1081739811.

ZIP4 upregulation aggravates nucleus pulposus cell degradation by promoting inflammation and oxidative stress by mediating the HDAC4-FoxO3a axis

Mingkui Shen, Kuankuan Li, Lulu Wang, Li Feng, Xinyu Zhang, Haoping Zhang, Honggang Zhou, Guoxian Pei

Aging (Albany NY) 2024 Jan 15; 16(1): 685–700. Published online 2024 Jan 12. doi: 10.18632/aging.205412

PMCID:: PMC10817398

Abstract Article PDF–2.6M

Select item 1080340912.

The Role of microRNA-23a-3p in the Progression of Human Aging Process by Targeting FOXO3a

Shan Wang, Ying Sun, Lan Yao, Yunli Xing, Huayu Yang, Qing Ma

Mol Biotechnol. 2024; 66(2): 277–287. Published online 2023 Apr 23. doi: 10.1007/s12033-023-00746-7

PMCID:: PMC10803409

Abstract Article PDF–1.8M

Select item 1074231913.

FoxO3a Drives the Metabolic Reprogramming in Tamoxifen-Resistant Breast Cancer Cells Restoring Tamoxifen Sensitivity

Marco Fiorillo, Elena Ricci, Mariarosa Fava, Camilla Longobucco, Federica Sotgia, Pietro Rizza, Marilena Lanzino, Daniela Bonofiglio, Francesca Luisa Conforti, Stefania Catalano, Ines Barone, Catia Morelli, Saveria Aquila, Michael P. Lisanti, Diego Sisci

Cells. 2023 Dec; 12(24): 2777. Published online 2023 Dec 6. doi: 10.3390/cells12242777

PMCID:: PMC10742319

Abstract Article PDF–5.4M

Select item 1065182214.

Proteomic basis of mortality resilience mediated by FOXO3 longevity genotype

Timothy A. Donlon, Brian J. Morris, Randi Chen, Eunjung Lim, Eric K. Morgen, Kristen Fortney, Naisha Shah, Kamal H. Masaki, Bradley J. Willcox

GeroScience. 2023 Aug; 45(4): 2303–2324. Published online 2023 Mar 7. doi: 10.1007/s11357-023-00740-6

PMCID:: PMC10651822

Abstract Article PDF–2.2M

Select item 1051542415.

FOXO3 and PTEN expression in the ovary of girls with extra-gonadal cancer with or without chemotherapy treatment prior to cryopreservation

María Itatí Albamonte, Lara Y. Calabró, Mirta S. Albamonte, Alfredo D. Vitullo

BMC Womens Health. 2023; 23: 509. Published online 2023 Sep 22. doi: 10.1186/s12905-023-02648-x

PMCID:: PMC10515424

Abstract Article PDF–2.7M

Select item 1042325916.

The APC/C E3 ligase subunit ANAPC11 mediates FOXO3 protein degradation to promote cell proliferation and lymph node metastasis in urothelial bladder cancer

Dong Yan, Qingqing He, Lu Pei, Meihua Yang, Lifang Huang, Jianqiu Kong, Wang He, Hao Liu, Shizhong Xu, Haide Qin, Tianxin Lin, Jian Huang

Cell Death Dis. 2023 Aug; 14(8): 516. Published online 2023 Aug 12. doi: 10.1038/s41419-023-06000-x

PMCID:: PMC10423259

Abstract Article PDF–9.6M

Select item 1032981417.

Expression of forkhead transcription factors in human granulosa cells

Margareta D. Pisarska, Fang-Ting Kuo, Dahai Tang, Parham Zarrini, Salma Khan, Aline Ketefian

Fertil Steril. Author manuscript; available in PMC 2023 Jul 9.

Published in final edited form as: Fertil Steril. 2009 Apr; 91(4 Suppl): 1392–1394. Published online 2008 Aug 9. doi: 10.1016/j.fertnstert.2008.04.054

PMCID:: PMC10329814

Abstract Article PDF–338K

Select item 1031405918.

FOXO3A acts as immune response modulator in human virus-negative inflammatory cardiomyopathy

Kamila Makrutzki-Zlotek, Felicitas Escher, Zehra Karadeniz, Ganna Aleshcheva, Heiko Pietsch, Konstanze Küchler, Heinz-Peter Schultheiss, Bettina Heidecker, Wolfgang Poller, Ulf Landmesser, Carmen Scheibenbogen, Tharusan Thevathasan, Carsten Skurk

Heart. 2023 Jun; 109(11): 846–856. Published online 2023 Jan 26. doi: 10.1136/heartjnl-2022-321732

PMCID:: PMC10314059

Abstract Article PDF–1.7M

Select item 1030574019.

Single-nucleus profiling unveils a geroprotective role of the FOXO3 in primate skeletal muscle aging

Ying Jing, Yuesheng Zuo, Yang Yu, Liang Sun, Zhengrong Yu, Shuai Ma, Qian Zhao, Guoqiang Sun, Huifang Hu, Jingyi Li, Daoyuan Huang, Lixiao Liu, Jiaming Li, Zijuan Xin, Haoyan Huang, Juan Carlos Izpisua Belmonte, Weiqi Zhang, Si Wang, Jing Qu, Guang-Hui Liu

Protein Cell. 2023 Jul; 14(7): 499–514. Published online 2022 Nov 22. doi: 10.1093/procel/pwac061

PMCID:: PMC10305740

Abstract Article PDF–6.9M

Select item 1026276320.

The COPS3-FOXO3 positive feedback loop regulates autophagy to promote cisplatin resistance in osteosarcoma

Jianfang Niu, Taiqiang Yan, Wei Guo, Wei Wang, Tingting Ren, Yi Huang, Zhiqing Zhao, Yiyang Yu, Chenglong Chen, Qingshan Huang, Jingbing Lou, Lei Guo

Autophagy. 2023; 19(6): 1693–1710. Published online 2022 Nov 30. doi: 10.1080/15548627.2022.2150003

PMCID:: PMC10262763

Abstract Article PDF–4.9M

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