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Select item 107896811.

Bone morphogenetic protein 6 induces downregulation of pentraxin 3 expression in human granulosa lutein cells in women with polycystic ovary syndrome

Xin Xin, Hsun-Ming Chang, Peter C. K. Leung, Li Dong, Jiaxi Li, Fang Lian, Haicui Wu

J Assist Reprod Genet. 2024 Jan; 41(1): 31–48. Published online 2023 Nov 6. doi: 10.1007/s10815-023-02972-z

PMCID:: PMC10789681

Abstract Article PDF–1.3M

Select item 95093602.

RNF4~RGMb~BMP6 axis required for osteogenic differentiation and cancer cell survival

Rostislav Novak, Yamen Abu Ahmad, Michael Timaner, Eliya Bitman-Lotan, Avital Oknin-Vaisman, Roi Horwitz, Oliver Hartmann, Michaela Reissland, Viktoria Buck, Mathias Rosenfeldt, David Nikomarov, Markus Elmar Diefenbacher, Yuval Shaked, Amir Orian

Cell Death Dis. 2022 Sep; 13(9): 820. Published online 2022 Sep 24. doi: 10.1038/s41419-022-05262-1

PMCID:: PMC9509360

Abstract Article PDF–4.2M

Select item 92316233.

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1

Boris Simonetti, James L. Daly, Lorena Simón-Gracia, Katja Klein, Saroja Weeratunga, Carlos Antón-Plágaro, Allan Tobi, Lorna Hodgson, Philip A. Lewis, Kate J. Heesom, Deborah K. Shoemark, Andrew D. Davidson, Brett M. Collins, Tambet Teesalu, Yohei Yamauchi, Peter J. Cullen

Proc Natl Acad Sci U S A. 2022 Jun 21; 119(25): e2201980119. Published online 2022 Jun 13. doi: 10.1073/pnas.2201980119

PMCID:: PMC9231623

Abstract Article PDF–6.0M

Select item 87607714.

Immunohistochemical analysis revealed the expression of bone morphogenetic proteins-4, 6, 7, and 9 in human induced membrane samples treated with the Masquelet technique

Takahiro Niikura, Takahiro Oda, Naoe Jimbo, Masato Komatsu, Keisuke Oe, Tomoaki Fukui, Tomoyuki Matsumoto, Shinya Hayashi, Takehiko Matsushita, Tomoo Itoh, Ryosuke Kuroda

J Orthop Surg Res. 2022; 17: 29. Published online 2022 Jan 15. doi: 10.1186/s13018-022-02922-y

PMCID:: PMC8760771

Abstract Article PDF–2.3M

Select item 86662735.

Runx3 regulates iron metabolism via modulation of BMP signalling

Hyun‐Yi Kim, Jong‐Min Lee, You‐Soub Lee, Shujin Li, Seung‐Jun Lee, Suk‐Chul Bae, Han‐Sung Jung

Cell Prolif. 2021 Dec; 54(12): e13138. Published online 2021 Oct 6. doi: 10.1111/cpr.13138

PMCID:: PMC8666273

Abstract Article PDF–2.5M

Select item 86376366.

Bone morphogenetic protein 6–mediated crosstalk between endothelial cells and hepatocytes recapitulates the iron-sensing pathway in vitro

Shijin Wang, Cheng Chen, Linna Yu, Johannes Mueller, Vanessa Rausch, Sebastian Mueller

J Biol Chem. 2021 Dec; 297(6): 101378. Published online 2021 Nov 2. doi: 10.1016/j.jbc.2021.101378

PMCID:: PMC8637636

Abstract Article PDF–1.4M

Select item 81650307.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 76850538.

Combinatorial use of bone morphogenetic protein 6, noggin and SOST significantly predicts cancer progression

Hiu‐Fung Yuen, Cian M. McCrudden, Claire Grills, Shu‐Dong Zhang, Yu‐Han Huang, Ka‐Kui Chan, Yuen‐Piu Chan, Michelle Lok‐Yee Wong, Simon Law, Gopesh Srivastava, Dean A. Fennell, Glenn Dickson, Mohamed El‐Tanani, Kwok‐Wah Chan

Cancer Sci. 2012 Jun; 103(6): 1145–1154. Published online 2012 Apr 3. doi: 10.1111/j.1349-7006.2012.02252.x

PMCID:: PMC7685053

Abstract Article PDF–900K

Select item 74572819.

Synergistic interaction of hTGF-β₃ with hBMP-6 promotes articular cartilage formation in chitosan scaffolds with hADSCs: implications for regenerative medicine

Yijiang Huang, Daniel Seitz, Yan Chevalier, Peter E. Müller, Volkmar Jansson, Roland M. Klar

BMC Biotechnol. 2020; 20: 48. Published online 2020 Aug 27. doi: 10.1186/s12896-020-00641-y

PMCID:: PMC7457281

Abstract Article PDF–10M

Select item 745285210.

BMP6 Regulates Corneal Epithelial Cell Stratification by Coordinating Their Proliferation and Differentiation and Is Upregulated in Pterygium

Anil Tiwari, Sudha Swamynathan, Gregory Campbell, Vishal Jhanji, Shivalingappa K. Swamynathan

Invest Ophthalmol Vis Sci. 2020 Aug; 61(10): 46. Published online 2020 Aug 26. doi: 10.1167/iovs.61.10.46

PMCID:: PMC7452852

Abstract Article PDF–1.6M

Select item 734646911.

Association analysis of polymorphisms rs12997 in ACVR1 and rs1043784 in BMP6 genes involved in bone morphogenic protein signaling pathway in primary angle-closure and pseudoexfoliation glaucoma patients of Saudi origin

Altaf A. Kondkar, Tahira Sultan, Taif A. Azad, Essam A. Osman, Faisal A. Almobarak, Saleh A. Al-Obeidan

BMC Med Genet. 2020; 21: 145. Published online 2020 Jul 8. doi: 10.1186/s12881-020-01076-0

PMCID:: PMC7346469

Abstract Article PDF–831K

Select item 703152112.

Inhibition of bone morphogenetic protein 6 receptors ameliorates Sjögren’s syndrome in mice

Hongen Yin, Lovika Kalra, Zhennan Lai, Maria C. Guimaro, Lauren Aber, Blake M. Warner, Drew Michael, Nan Zhang, Javier Cabrera-Perez, Arif Karim, William D. Swaim, Sandra Afione, Alexandria Voigt, Cuong Q. Nguyen, Paul B. Yu, Donald B. Bloch, John A. Chiorini

Sci Rep. 2020; 10: 2967. Published online 2020 Feb 19. doi: 10.1038/s41598-020-59443-z

PMCID:: PMC7031521

Abstract Article PDF–1.9M

Select item 702376613.

miR-765 inhibits the osteogenic differentiation of human bone marrow mesenchymal stem cells by targeting BMP6 via regulating the BMP6/Smad1/5/9 signaling pathway

Tao Wang, Chao Zhang, Cihu Wu, Jianyun Liu, Hui Yu, Xiaoou Zhou, Jie Zhang, Xinping Wang, Shan He, Xiaoyuan Xu, Baicheng Ma, Xiangxin Che, Weidong Li

Stem Cell Res Ther. 2020; 11: 62. Published online 2020 Feb 14. doi: 10.1186/s13287-020-1579-0

PMCID:: PMC7023766

Abstract Article PDF–3.4M

Select item 700536614.

Erythroferrone lowers hepcidin by sequestering BMP2/6 heterodimer from binding to the BMP type I receptor ALK3

Chia-Yu Wang, Yang Xu, Lisa Traeger, Deniz Y. Dogan, Xia Xiao, Andrea U. Steinbicker, Jodie L. Babitt

Blood. 2020 Feb 6; 135(6): 453–456. Prepublished online 2019 Dec 4. doi: 10.1182/blood.2019002620

PMCID:: PMC7005366

Article

Select item 660915315.

Nrf2 controls iron homeostasis in haemochromatosis and thalassaemia via Bmp6 and hepcidin

Pei Jin Lim, Tiago L. Duarte, João Arezes, Daniel Garcia-Santos, Amel Hamdi, Sant-Rayn Pasricha, Andrew E. Armitage, Hema Mehta, Sarah Wideman, Ana G. Santos, Andreia Santos-Gonçalves, Alireza Morovat, Jim R. Hughes, Elizabeth Soilleux, Chia-Yu Wang, Abraham L. Bayer, Paul Klenerman, Christian B. Willberg, Richard C. Hartley, Michael P. Murphy, Jodie L. Babitt, Prem Ponka, Graça Porto, Hal Drakesmith

Nat Metab. Author manuscript; available in PMC 2019 Nov 1.

Published in final edited form as: Nat Metab. 2019 May; 1(5): 519–531. Published online 2019 May 13. doi: 10.1038/s42255-019-0063-6

PMCID:: PMC6609153

Abstract Article PDF–2.4M

Select item 659005816.

Antiviral activity of BMPs and Activins

Lucy A. Eddowes, Kinda Al-Hourani, Narayan Ramamurthy, Jamie Frankish, Hannah T Baddock, Cynthia Sandor, John D. Ryan, Dahlene N. Fusco, João Arezes, Eleni Giannoulatou, Sara Boninsegna, Stephane Chevaliez, Benjamin M. J. Owens, Chia Chi Sun, Paolo Fabris, Maria Teresa Giordani, Diego Martines, Slobodan Vukicevic, John Crowe, Herbert Y. Lin, Jan Rehwinkel, Peter J. McHugh, Marco Binder, Jodie L. Babitt, Raymond T. Chung, Matthew W. Lawless, Andrew E. Armitage, Caleb Webber, Paul Klenerman, Hal Drakesmith

Nat Microbiol. Author manuscript; available in PMC 2019 Aug 1.

Published in final edited form as: Nat Microbiol. 2019 Feb; 4(2): 339–351. Published online 2018 Dec 3. doi: 10.1038/s41564-018-0301-9

PMCID:: PMC6590058

Abstract Article PDF–2.0M

Select item 623815517.

Erythroferrone inhibits the induction of hepcidin by BMP6

João Arezes, Niall Foy, Kirsty McHugh, Anagha Sawant, Doris Quinkert, Virginie Terraube, Alette Brinth, May Tam, Edward R. LaVallie, Stephen Taylor, Andrew E. Armitage, Sant-Rayn Pasricha, Orla Cunningham, Matthew Lambert, Simon J. Draper, Reema Jasuja, Hal Drakesmith

Blood. 2018 Oct 4; 132(14): 1473–1477. Prepublished online 2018 Aug 10. doi: 10.1182/blood-2018-06-857995

PMCID:: PMC6238155

Abstract Article

Select item 567858118.

RNA-binding activity of TRIM25 is mediated by its PRY/SPRY domain and is required for ubiquitination

Nila Roy Choudhury, Gregory Heikel, Maryia Trubitsyna, Peter Kubik, Jakub Stanislaw Nowak, Shaun Webb, Sander Granneman, Christos Spanos, Juri Rappsilber, Alfredo Castello, Gracjan Michlewski

BMC Biol. 2017; 15: 105. Published online 2017 Nov 8. doi: 10.1186/s12915-017-0444-9

PMCID:: PMC5678581

Abstract Article PDF–3.2M

Select item 563670219.

Role of bone morphogenetic proteins in sprouting angiogenesis: differential BMP receptor-dependent signaling pathways balance stalk vs. tip cell competence

Andreas Benn, Christian Hiepen, Marc Osterland, Christof Schütte, An Zwijsen, Petra Knaus

FASEB J. 2017 Nov; 31(11): 4720–4733. Published online 2017 Jul 21. doi: 10.1096/fj.201700193RR

PMCID:: PMC5636702

Abstract Article

Select item 535451420.

Biochemical and Cellular Analysis Reveals Ligand Binding Specificities, a Molecular Basis for Ligand Recognition, and Membrane Association-dependent Activities of Cripto-1 and Cryptic

Senem Aykul, Anthony Parenti, Kit Yee Chu, Jake Reske, Monique Floer, Amy Ralston, Erik Martinez-Hackert

J Biol Chem. 2017 Mar 10; 292(10): 4138–4151. Published online 2017 Jan 26. doi: 10.1074/jbc.M116.747501

PMCID:: PMC5354514

Abstract Article PDF–3.1M

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