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Items: 1 to 20 of 27

1.
A dual-acting DNASE1/DNASE1L3 biologic prevents autoimmunity and death in genetic and induced lupus models
Paul R. Stabach, Dominique Sims, Eduardo Gomez-Bañuelos, Sandra Zehentmeier, Kris Dammen-Brower, Andrew Bernhisel, Sophia Kujawski, Sam G. Lopez, Michelle Petri, Daniel W. Goldman, Ethan R. Lester, Quan Le, Tayyaba Ishaq, Hana Kim, Shivani Srivastava, Deepika Kumar, Joao P. Pereira, Kevin J. Yarema, Fotios Koumpouras, Felipe Andrade, Demetrios T. Braddock
JCI Insight. 2024 Jul 22; 9(14): e177003. Published online 2024 Jun 18. doi: 10.1172/jci.insight.177003
PMCID:
PMC11383374
AbstractArticlePDF–14M
2.
The protective effect of DNase I in retinal vein occlusion
Guohua Deng, Xi Zou, Zhinan Liu, Hang Ren, Yanting Li, Bin Chen, Jun Zhang
Biomol Biomed. 2024 Apr 1; 24(2): 387–394. Published online 2024 Apr 1. doi: 10.17305/bb.2023.9780
PMCID:
PMC10950336
AbstractArticlePDF–4.5M
3.
Significant Association of DNASE1 Variable Number Tandem Repeats and Single Nucleotide Polymorphisms With Gastric Cancer
Ali Kafil, Parisa Mohamadynejad, Mehdi Moghanibashi
Br J Biomed Sci. 2022; 79: 10526. Published online 2022 May 13. doi: 10.3389/bjbs.2022.10526
PMCID:
PMC9302541
AbstractArticlePDF–748K
4.
Genome-wide CRISPR screens using isogenic cells reveal vulnerabilities conferred by loss of tumor suppressors
Xu Feng, Mengfan Tang, Merve Dede, Dan Su, Guangsheng Pei, Dadi Jiang, Chao Wang, Zhen Chen, Mi Li, Litong Nie, Yun Xiong, Siting Li, Jeong-Min Park, Huimin Zhang, Min Huang, Klaudia Szymonowicz, Zhongming Zhao, Traver Hart, Junjie Chen
Sci Adv. 2022 May; 8(19): eabm6638. Published online 2022 May 13. doi: 10.1126/sciadv.abm6638
PMCID:
PMC9106303
AbstractArticlePDF–918K
5.
Deoxyribonuclease 1 Q222R single nucleotide polymorphism and long-term mortality after acute myocardial infarction
Thomas M. Hofbauer, Andreas Mangold, Anna S. Ondracek, Adelheid Panzenböck, Thomas Scherz, Julian Müller, Klaus Distelmaier, Veronika Seidl, Stefan Kastl, Martina Müller-Nurasyid, Annette Peters, Konstantin Strauch, Robert Winker, Evelyne Wohlschläger-Krenn, Sonja Nistler, Irene M. Lang
Basic Res Cardiol. 2021; 116(1): 29. Published online 2021 Apr 23. doi: 10.1007/s00395-021-00864-w
PMCID:
PMC8064981
AbstractArticlePDF–938K
6.
AAV‐mediated gene transfer of DNase I in the liver of mice with colorectal cancer reduces liver metastasis and restores local innate and adaptive immune response
Yujia Xia, Jiayi He, Hongji Zhang, Han Wang, George Tetz, Casey A. Maguire, Yu Wang, Amblessed Onuma, Dmitry Genkin, Victor Tetz, Alexey Stepanov, Stanislav Terekhov, Valeria Ukrainskaya, Hai Huang, Allan Tsung
Mol Oncol. 2020 Nov; 14(11): 2920–2935. Published online 2020 Sep 5. doi: 10.1002/1878-0261.12787
PMCID:
PMC7607180
AbstractArticlePDF–4.2M
7.
Evaluation of the functional effects of genetic variants‒missense and nonsense SNPs, indels and copy number variations‒in the gene encoding human deoxyribonuclease I potentially implicated in autoimmunity
Misuzu Ueki, Kaori Kimura-Kataoka, Junko Fujihara, Reiko Iida, Yasuyuki Kawai, Akari Kusaka, Takamitsu Sasaki, Haruo Takeshita, Toshihiro Yasuda
Sci Rep. 2019; 9: 13660. Published online 2019 Sep 20. doi: 10.1038/s41598-019-49935-y
PMCID:
PMC6754452
AbstractArticlePDF–1.1M
8.
RNA-binding activity of TRIM25 is mediated by its PRY/SPRY domain and is required for ubiquitination
Nila Roy Choudhury, Gregory Heikel, Maryia Trubitsyna, Peter Kubik, Jakub Stanislaw Nowak, Shaun Webb, Sander Granneman, Christos Spanos, Juri Rappsilber, Alfredo Castello, Gracjan Michlewski
BMC Biol. 2017; 15: 105. Published online 2017 Nov 8. doi: 10.1186/s12915-017-0444-9
PMCID:
PMC5678581
AbstractArticlePDF–3.2M
9.
Deoxyribonuclease 1 reduces pathogenic effects of cigarette smoke exposure in the lung
Paul T. King, Roleen Sharma, Kim M. O’Sullivan, Judy Callaghan, Lovisa Dousha, Belinda Thomas, Saleela Ruwanpura, Steven Lim, Michael W. Farmer, Barton R. Jennings, Michaela Finsterbusch, Gavin Brooks, Stavros Selemidis, Gary P. Anderson, Stephen R. Holdsworth, Philip G. Bardin
Sci Rep. 2017; 7: 12128. Published online 2017 Sep 21. doi: 10.1038/s41598-017-12474-5
PMCID:
PMC5608940
AbstractArticlePDF–3.0M
10.
Single Nucleotide Polymorphisms in the BDNF, VDR, and DNASE 1 Genes in Dry Eye Disease Patients: A Case-Control Study
Joelle A. Hallak, Sapna Tibrewal, Neil Mohindra, Xiaoyi Gao, Sandeep Jain
Invest Ophthalmol Vis Sci. 2015 Sep; 56(10): 5990–5996. Published online 2015 Sep 22. doi: 10.1167/iovs.15-17036
PMCID:
PMC5102496
AbstractArticlePDF–290K
11.
DNase I aggravates islet β-cell apoptosis in type 2 diabetes
BIN ZHU, LEI ZHANG, YUE-YING ZHANG, LEI WANG, XIN-GANG LI, TENG LIU, YU-KE FU, YAN-FEI ZHENG, PING LI, ZHI-GANG ZHAO
Mol Med Rep. 2016 Jun; 13(6): 4577–4584. Published online 2016 Apr 11. doi: 10.3892/mmr.2016.5102
PMCID:
PMC4878546
AbstractArticlePDF–1.3M
12.
TNFα Amplifies DNaseI Expression in Renal Tubular Cells while IL-1β Promotes Nuclear DNaseI Translocation in an Endonuclease-Inactive Form
Dhivya Thiyagarajan, Ole Petter Rekvig, Natalya Seredkina
PLoS One. 2015; 10(6): e0129485. Published online 2015 Jun 11. doi: 10.1371/journal.pone.0129485
PMCID:
PMC4465975
AbstractArticlePDF–4.4M
13.
Identification of the Functional Alleles of the Nonsynonymous Single-Nucleotide Polymorphisms Potentially Implicated in Systemic Lupus Erythematosus in the Human Deoxyribonuclease I Gene
Kaori Kimura-Kataoka, Misuzu Ueki, Haruo Takeshita, Junko Fujihara, Reiko Iida, Yasuyuki Kawai, Toshihiro Yasuda
DNA Cell Biol. 2014 Aug 1; 33(8): 492–502. doi: 10.1089/dna.2014.2368
PMCID:
PMC4117266
AbstractArticlePDF–344K
14.
In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine
Simona Principe, E. Ellen Jones, Yunee Kim, Ankit Sinha, Julius O. Nyalwidhe, Jasmin Brooks, O. John Semmes, Dean A. Troyer, Raymond S. Lance, Thomas Kislinger, Richard R. Drake
Proteomics. Author manuscript; available in PMC 2014 May 1.
Published in final edited form as: Proteomics. 2013 May; 13(0): 1667–1671. Published online 2013 Apr 23. doi: 10.1002/pmic.201200561
PMCID:
PMC3773505
AbstractArticlePDF–630K
15.
Silencing of Renal DNaseI in Murine Lupus Nephritis Imposes Exposure of Large Chromatin Fragments and Activation of Toll Like Receptors and the Clec4e
Dhivya Thiyagarajan, Silje Fismen, Natalya Seredkina, Søren Jacobsen, Thomas Elung-Jensen, Anne-Lise Kamper, Christopher Graham Fenton, Ole Petter Rekvig, Elin Synnøve Mortensen
PLoS One. 2012; 7(3): e34080. Published online 2012 Mar 30. doi: 10.1371/journal.pone.0034080
PMCID:
PMC3316608
AbstractArticlePDF–2.3M
16.
Induction and Maintenance of IL-4 Expression Are Regulated Differently by the 3′ Enhancer in CD4 T Cells
M. Hanief Sofi, Yu Qiao, K. Mark Ansel, Masato Kubo, Cheong-Hee Chang
J Immunol. Author manuscript; available in PMC 2012 Mar 1.
Published in final edited form as: J Immunol. 2011 Mar 1; 186(5): 2792–2799. Published online 2011 Jan 31. doi: 10.4049/jimmunol.1003353
PMCID:
PMC3188392
AbstractArticlePDF–1.5M
17.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
18.
Variation at the NFATC2 Locus Increases the Risk of Thiazolidinedione-Induced Edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) Study
Swneke D. Bailey, Changchun Xie, Ron Do, Alexandre Montpetit, Rafael Diaz, Viswanathan Mohan, Bernard Keavney, Salim Yusuf, Hertzel C. Gerstein, James C. Engert, Sonia Anand, on behalf of the DREAM investigators
Diabetes Care. 2010 Oct; 33(10): 2250–2253. Published online 2010 Jul 13. doi: 10.2337/dc10-0452
PMCID:
PMC2945168
AbstractArticlePDF–153K
19.
Renal Dnase1 Enzyme Activity and Protein Expression Is Selectively Shut Down in Murine and Human Membranoproliferative Lupus Nephritis
Svetlana N. Zykova, Anders A. Tveita, Ole Petter Rekvig
PLoS One. 2010; 5(8): e12096. Published online 2010 Aug 10. doi: 10.1371/journal.pone.0012096
PMCID:
PMC2938370
AbstractArticlePDF–2.8M
20.
Impairment of neutrophil extracellular trap degradation is associated with lupus nephritis
Abdul Hakkim, Barbara G. Fürnrohr, Kerstin Amann, Britta Laube, Ulrike Abu Abed, Volker Brinkmann, Martin Herrmann, Reinhard E. Voll, Arturo Zychlinsky
Proc Natl Acad Sci U S A. 2010 May 25; 107(21): 9813–9818. Published online 2010 May 3. doi: 10.1073/pnas.0909927107
PMCID:
PMC2906830
AbstractArticlePDF–653K

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