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Select item 102634351.

Diminuição dos Níveis Séricos do Receptor Solúvel da Oncostatina M (sOSMR) e Glicoproteína 130 (sgp130) em Pacientes com Doença Arterial Coronariana

Vanessa Mylenna Florêncio de Carvalho, Priscilla Stela Santana de Oliveira, Amanda Pinheiro Barros de Albuquerque, Moacyr Jesus Barreto de Melo Rêgo, Michelle Melgarejo da Rosa, Dinaldo Cavalcanti de Oliveira, Michelly Cristiny Pereira, Maira Galdino da Rocha Pitta

Arq Bras Cardiol. 2023 Apr; 120(4): e20220326. Portuguese. Published online 2023 Apr 4. doi: 10.36660/abc.20220326

PMCID:: PMC10263435

Abstract Article PDF–986K

Select item 92316232.

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1

Boris Simonetti, James L. Daly, Lorena Simón-Gracia, Katja Klein, Saroja Weeratunga, Carlos Antón-Plágaro, Allan Tobi, Lorna Hodgson, Philip A. Lewis, Kate J. Heesom, Deborah K. Shoemark, Andrew D. Davidson, Brett M. Collins, Tambet Teesalu, Yohei Yamauchi, Peter J. Cullen

Proc Natl Acad Sci U S A. 2022 Jun 21; 119(25): e2201980119. Published online 2022 Jun 13. doi: 10.1073/pnas.2201980119

PMCID:: PMC9231623

Abstract Article PDF–6.0M

Select item 88365423.

The Role of Oncostatin M and Its Receptor Complexes in Cardiomyocyte Protection, Regeneration, and Failure

Thomas Kubin, Praveen Gajawada, Peter Bramlage, Stefan Hein, Benedikt Berge, Ayse Cetinkaya, Heiko Burger, Markus Schönburg, Wolfgang Schaper, Yeong-Hoon Choi, Manfred Richter

Int J Mol Sci. 2022 Feb; 23(3): 1811. Published online 2022 Feb 5. doi: 10.3390/ijms23031811

PMCID:: PMC8836542

Abstract Article PDF–8.4M

Select item 86834364.

Heterocellular OSM-OSMR signalling reprograms fibroblasts to promote pancreatic cancer growth and metastasis

Brian Y. Lee, Elizabeth K. J. Hogg, Christopher R. Below, Alexander Kononov, Adrian Blanco-Gomez, Felix Heider, Jingshu Xu, Colin Hutton, Xiaohong Zhang, Tamara Scheidt, Kenneth Beattie, Angela Lamarca, Mairéad McNamara, Juan W. Valle, Claus Jørgensen

Nat Commun. 2021; 12: 7336. Published online 2021 Dec 17. doi: 10.1038/s41467-021-27607-8

PMCID:: PMC8683436

Abstract Article PDF–6.4M

Select item 85309815.

Oncostatin M Receptor-targeted antibodies suppress STAT3 signaling and inhibit ovarian cancer growth

Anjali Geethadevi, Ajay Nair, Deepak Parashar, Zhiqiang Ku, Wei Xiong, Hui Deng, Yongsheng Li, Jasmine George, Donna M. McAllister, Yunguang Sun, Ishaque P. Kadamberi, Prachi Gupta, Michael B. Dwinell, William H. Bradley, Janet S. Rader, Hallgeir Rui, Robert F. Schwabe, Ningyan Zhang, Sunila Pradeep, Zhiqiang An, Pradeep Chaluvally-Raghavan

Cancer Res. Author manuscript; available in PMC 2022 Apr 15.

Published in final edited form as: Cancer Res. 2021 Oct 15; 81(20): 5336–5352. Published online 2021 Aug 11. doi: 10.1158/0008-5472.CAN-21-0483

PMCID:: PMC8530981

Abstract Article PDF–3.3M

Select item 83105496.

OSMRβ mutants enhance basal keratinocyte differentiation via inactivation of the STAT5/KLF7 axis in PLCA patients

Jun Liu, Junchen Chen, Yadan Zhong, Xiaoling Yu, Ping Lu, Jianqi Feng, Xin Zhang, Shufeng Ma, Chao Yang, Bin Yang, Zhili Rong

Protein Cell. 2021 Aug; 12(8): 653–661. Published online 2021 Jan 27. doi: 10.1007/s13238-020-00818-3

PMCID:: PMC8310549

Article PDF–1.9M

Select item 81650307.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 80678048.

The OSMR Gene Is Involved in Hirschsprung Associated Enterocolitis Susceptibility through an Altered Downstream Signaling

Tiziana Bachetti, Francesca Rosamilia, Martina Bartolucci, Giuseppe Santamaria, Manuela Mosconi, Serenella Sartori, Maria Rosaria De Filippo, Marco Di Duca, Valentina Obino, Stefano Avanzini, Domenico Mavilio, Simona Candiani, Andrea Petretto, Alessio Pini Prato, Isabella Ceccherini, Francesca Lantieri

Int J Mol Sci. 2021 Apr; 22(8): 3831. Published online 2021 Apr 7. doi: 10.3390/ijms22083831

PMCID:: PMC8067804

Abstract Article PDF–2.1M

Select item 75182409.

Whole-Exome Analysis of Metaplastic Breast Carcinomas with Extensive Osseous Differentiation

Francisco Beca, Ana Paula Martins Sebastiao, Fresia Pareja, Kimberly Dessources, John R. Lozada, Felipe Geyer, Pier Selenica, Nebras Zeizafoun, Hannah Y. Wen, Larry Norton, Edi Brogi, Britta Weigelt, Jorge S Reis-Filho

Histopathology. Author manuscript; available in PMC 2021 Aug 1.

Published in final edited form as: Histopathology. 2020 Aug; 77(2): 321–326. doi: 10.1111/his.14088

PMCID:: PMC7518240

Abstract Article PDF–578K

Select item 743142810.

OSMR controls glioma stem cell respiration and confers resistance of glioblastoma to ionizing radiation

Ahmad Sharanek, Audrey Burban, Matthew Laaper, Emilie Heckel, Jean-Sebastien Joyal, Vahab D. Soleimani, Arezu Jahani-Asl

Nat Commun. 2020; 11: 4116. Published online 2020 Aug 17. doi: 10.1038/s41467-020-17885-z

PMCID:: PMC7431428

Abstract Article PDF–4.0M

Select item 737951111.

Feline Interleukin-31 shares overlapping epitopes with Oncostatin M Receptor and IL-31RA

Angelica V. Medina-Cucurella, Gary F. Bammert, William Dunkle, Christopher Javens, Yaqi Zhu, Veronica T. Mutchler, Janet T. Teel, Caitlin A. Stein, Steve A. Dunham, Timothy A. Whitehead

Biochemistry. Author manuscript; available in PMC 2021 Jun 16.

Published in final edited form as: Biochemistry. 2020 Jun 16; 59(23): 2171–2181. Published online 2020 Jun 4. doi: 10.1021/acs.biochem.0c00176

PMCID:: PMC7379511

Abstract Article PDF–1.9M

Select item 716998312.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x

PMCID:: PMC7169983

Abstract Article PDF–5.4M

Select item 713288113.

Annexin A2–STAT3–Oncostatin M receptor axis drives phenotypic and mesenchymal changes in glioblastoma

Yuji Matsumoto, Tomotsugu Ichikawa, Kazuhiko Kurozumi, Yoshihiro Otani, Atsushi Fujimura, Kentaro Fujii, Yusuke Tomita, Yasuhiko Hattori, Atsuhito Uneda, Nobushige Tsuboi, Keisuke Kaneda, Keigo Makino, Isao Date

Acta Neuropathol Commun. 2020; 8: 42. Published online 2020 Apr 5. doi: 10.1186/s40478-020-00916-7

PMCID:: PMC7132881

Abstract Article PDF–6.0M

Select item 701708714.

Oncostatin M, A Profibrogenic Mediator Overexpressed in Non-Alcoholic Fatty Liver Disease, Stimulates Migration of Hepatic Myofibroblasts

Beatrice Foglia, Salvatore Sutti, Dario Pedicini, Stefania Cannito, Claudia Bocca, Marina Maggiora, Maria Rosaria Bevacqua, Chiara Rosso, Elisabetta Bugianesi, Emanuele Albano, Erica Novo, Maurizio Parola

Cells. 2020 Jan; 9(1): 28. Published online 2019 Dec 20. doi: 10.3390/cells9010028

PMCID:: PMC7017087

Abstract Article PDF–5.7M

Select item 694204415.

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity

Jae Jin Kim, Seo Yun Lee, Fade Gong, Anna M. Battenhouse, Daniel R. Boutz, Aarti Bashyal, Samantha T. Refvik, Cheng-Ming Chiang, Blerta Xhemalce, Tanya T. Paull, Jennifer S. Brodbelt, Edward M. Marcotte, Kyle M. Miller

Genes Dev. 2019 Dec 1; 33(23-24): 1751–1774. doi: 10.1101/gad.331231.119

PMCID:: PMC6942044

Abstract Article PDF–10M

Select item 670545716.

Oncostatin M Confers Neuroprotection against Ischemic Stroke

Sen Guo, Zuo-Zhi Li, Jun Gong, Mei Xiang, Peng Zhang, Guang-Nian Zhao, Mingchang Li, Ankang Zheng, Xueyong Zhu, Hao Lei, Tanaka Minoru, Hongliang Li

J Neurosci. 2015 Aug 26; 35(34): 12047–12062. doi: 10.1523/JNEUROSCI.1800-15.2015

PMCID:: PMC6705457

Abstract Article PDF–6.4M

Select item 637145617.

The role of oncostatin M receptor gene polymorphisms in bladder cancer

Shi Deng, Sheng yin He, Pan Zhao, Peng Zhang

World J Surg Oncol. 2019; 17: 30. Published online 2019 Feb 12. doi: 10.1186/s12957-018-1555-7

PMCID:: PMC6371456

Abstract Article PDF–690K

Select item 601687618.

OSMR gene effect on the pathogenesis of chronic autoimmune Urticaria via the JAK/STAT3 pathway

Xiao-Yan Luo, Qun Liu, Huan Yang, Qi Tan, Li-Qiang Gan, Fa-Liang Ren, Hua Wang

Mol Med. 2018; 24: 28. Published online 2018 Jun 5. doi: 10.1186/s10020-018-0025-6

PMCID:: PMC6016876

Abstract Article PDF–1.4M

Select item 593683519.

The AB loop and D-helix in binding site III of human Oncostatin M (OSM) are required for OSM receptor activation

Juan M. Adrian-Segarra, Natalie Schindler, Praveen Gajawada, Holger Lörchner, Thomas Braun, Jochen Pöling

J Biol Chem. 2018 May 4; 293(18): 7017–7029. Published online 2018 Mar 6. doi: 10.1074/jbc.RA118.001920

PMCID:: PMC5936835

Abstract Article PDF–4.0M

Select item 567858120.

RNA-binding activity of TRIM25 is mediated by its PRY/SPRY domain and is required for ubiquitination

Nila Roy Choudhury, Gregory Heikel, Maryia Trubitsyna, Peter Kubik, Jakub Stanislaw Nowak, Shaun Webb, Sander Granneman, Christos Spanos, Juri Rappsilber, Alfredo Castello, Gracjan Michlewski

BMC Biol. 2017; 15: 105. Published online 2017 Nov 8. doi: 10.1186/s12915-017-0444-9

PMCID:: PMC5678581

Abstract Article PDF–3.2M

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