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Select item 108033111.

LOX-1 acts as an N⁶-methyladenosine-regulated receptor for Helicobacter pylori by binding to the bacterial catalase

Judeng Zeng, Chuan Xie, Ziheng Huang, Chi H. Cho, Hung Chan, Qing Li, Hassan Ashktorab, Duane T. Smoot, Sunny H. Wong, Jun Yu, Wei Gong, Cong Liang, Hongzhi Xu, Huarong Chen, Xiaodong Liu, Justin C. Y. Wu, Margaret Ip, Tony Gin, Lin Zhang, Matthew T. V. Chan, Wei Hu, William K. K. Wu

Nat Commun. 2024; 15: 669. Published online 2024 Jan 22. doi: 10.1038/s41467-024-44860-9

PMCID:: PMC10803311

Abstract Article PDF–4.4M

Select item 97469012.

Lectin-like oxidized low-density lipoprotein receptor 1 attenuates pneumonia-induced lung injury

Filiz T. Korkmaz, Anukul T. Shenoy, Elise M. Symer, Lillia A. Baird, Christine V. Odom, Emad I. Arafa, Ernest L. Dimbo, Elim Na, William Molina-Arocho, Matthew Brudner, Theodore J. Standiford, Jawahar L. Mehta, Tatsuya Sawamura, Matthew R. Jones, Joseph P. Mizgerd, Katrina E. Traber, Lee J. Quinton

JCI Insight. 2022 Dec 8; 7(23): e149955. Published online 2022 Dec 8. doi: 10.1172/jci.insight.149955

PMCID:: PMC9746901

Abstract Article PDF–10M

Select item 87608893.

OxLDL Triggers Retrograde Translocation of Arginase 2 in Aortic Endothelial Cells via ROCK and Mitochondrial Processing Peptidase

Deepesh Pandey, Anil Bhunia, Young Jun Oh, Fumin Chang, Yehudit Bergman, Jae Hyung Kim, Janna Serbo, Tatiana N. Boronina, Robert N. Cole, Jennifer Van Eyk, Alan T. Remaley, Dan E. Berkowitz, Lewis Romer

Circ Res. Author manuscript; available in PMC 2022 Jan 15.

Published in final edited form as: Circ Res. 2014 Aug 1; 115(4): 450–459. Published online 2014 Jun 5. doi: 10.1161/CIRCRESAHA.115.304262

PMCID:: PMC8760889

Abstract Article PDF–2.3M

Select item 83333154.

Critical role of oxidized LDL receptor-1 in intravascular thrombosis in a severe influenza mouse model

Marumi Ohno, Akemi Kakino, Toshiki Sekiya, Naoki Nomura, Masashi Shingai, Tatsuya Sawamura, Hiroshi Kida

Sci Rep. 2021; 11: 15675. Published online 2021 Aug 3. doi: 10.1038/s41598-021-95046-y

PMCID:: PMC8333315

Abstract Article PDF–1.6M

Select item 81863765.

Oxidized low-density lipoprotein stimulates dendritic cells maturation via LOX-1-mediated MAPK/NF-κB pathway

D. Huang, W. Gao, H. Lu, J.Y. Qian, J.B. Ge

Braz J Med Biol Res. 2021; 54(9): e11062. Published online 2021 May 31. doi: 10.1590/1414-431X2021e11062

PMCID:: PMC8186376

Abstract Article PDF–596K

Select item 78318516.

Epac1 upregulates LOX-1 to promote foam cell formation and atherosclerosis development

William G. Robichaux, III, Fang C. Mei, Wenli Yang, Hui Wang, Hua Sun, Zhen Zhou, Dianna M. Milewicz, Ba-Bie Teng, Xiaodong Cheng

Arterioscler Thromb Vasc Biol. Author manuscript; available in PMC 2021 Dec 1.

Published in final edited form as: Arterioscler Thromb Vasc Biol. 2020 Dec; 40(12): e322–e335. Published online 2020 Oct 15. doi: 10.1161/ATVBAHA.119.314238

PMCID:: PMC7831851

Abstract Article PDF–1.2M

Select item 71421547.

Role of Lectin-like Oxidized LDL Receptor-1 and Syncytiotrophoblast Extracellular Vesicles in the Vascular Reactivity of Mouse Uterine Arteries During Pregnancy

Floor Spaans, Anita Quon, Raven Kirschenman, Jude S. Morton, Tatsuya Sawamura, Dionne S. Tannetta, Ian L. Sargent, Sandra T. Davidge

Sci Rep. 2020; 10: 6046. Published online 2020 Apr 8. doi: 10.1038/s41598-020-63205-2

PMCID:: PMC7142154

Abstract Article PDF–1.4M

Select item 68271158.

Deleterious role of endothelial lectin-like oxidized low-density lipoprotein receptor-1 in ischaemia/reperfusion cerebral injury

Alexander Akhmedov, Nicole R Bonetti, Martin F Reiner, Remo D Spescha, Heidi Amstalden, Mario Merlini, Daniel S Gaul, Candela Diaz-Cañestro, Sylvie Briand-Schumacher, Rebecca S Spescha, Aurora Semerano, Giacomo Giacalone, Gianluigi Savarese, Fabrizio Montecucco, Luka Kulic, Roger M Nitsch, Christian M Matter, Gerd A Kullak-Ublick, Maria Sessa, Thomas F Lüscher, Jürg H Beer, Luca Liberale, Giovanni G Camici

J Cereb Blood Flow Metab. 2019 Nov; 39(11): 2233–2245. Published online 2018 Aug 3. doi: 10.1177/0271678X18793266

Correction in:: J Cereb Blood Flow Metab. 2019 Nov; 39(11): NP1.

PMCID:: PMC6827115

Abstract Article PDF–829K

Select item 60098419.

Blockade of LOX-1 Prevents Endotoxin-Induced Acute Lung Inflammation and Injury in Mice

Ping Zhang, Ming-Cheh Liu, Lili Cheng, Mei Liang, Hong-long Ji, Jian Fu

J Innate Immun. Author manuscript; available in PMC 2018 Jun 20.

Published in final edited form as: J Innate Immun. 2009; 1(4): 358–365. Published online 2008 Oct 1. doi: 10.1159/000161070

PMCID:: PMC6009841

Abstract Article PDF–2.2M

Select item 595299710.

MicroRNA-98 regulates foam cell formation and lipid accumulation through repression of LOX-1

Yao Dai, Xiaoqin Wu, Dongsheng Dai, Jun Li, Jawahar L. Mehta

Redox Biol. 2018 Jun; 16: 255–262. Published online 2018 Mar 8. doi: 10.1016/j.redox.2018.03.003

PMCID:: PMC5952997

Abstract Article PDF–1.0M

Select item 558982211.

Human electronegative low-density lipoprotein modulates cardiac repolarization via LOX-1-mediated alteration of sarcolemmal ion channels

An-Sheng Lee, Yutao Xi, Chin-Hu Lai, Wei-Yu Chen, Hsien-Yu Peng, Hua-Chen Chan, Chu-Huang Chen, Kuan-Cheng Chang

Sci Rep. 2017; 7: 10889. Published online 2017 Sep 7. doi: 10.1038/s41598-017-10503-x

PMCID:: PMC5589822

Abstract Article PDF–2.3M

Select item 555448012.

Hyperoside inhibits the effects induced by oxidized low-density lipoprotein in vascular smooth muscle cells via oxLDL-LOX-1-ERK pathway

Zhengyu Zhang, Dongdong Zhang, Baoling Du, Zhiqiang Chen

Mol Cell Biochem. 2017; 433(1): 169–176. Published online 2017 Apr 22. doi: 10.1007/s11010-017-3025-x

PMCID:: PMC5554480

Abstract Article PDF–1.4M

Select item 546637813.

MicroRNA let-7g alleviates atherosclerosis via the targeting of LOX-1 in vitro and in vivo

Mingxin Liu, Guizhou Tao, Qifeng Liu, Kun Liu, Xinchun Yang

Int J Mol Med. 2017 Jul; 40(1): 57–64. Published online 2017 May 18. doi: 10.3892/ijmm.2017.2995

PMCID:: PMC5466378

Abstract Article PDF–1.1M

Select item 532774914.

Lectin-like, oxidized low-density lipoprotein receptor-1-deficient mice show resistance to age-related knee osteoarthritis

Kazuhiko Hashimoto, Yutaka Oda, Fumihisa Nakamura, Ryosuke Kakinoki, Masao Akagi

Eur J Histochem. 2017 Jan 23; 61(1): 2762. Published online 2017 Feb 14. doi: 10.4081/ejh.2017.2762

PMCID:: PMC5327749

Abstract Article PDF–686K

Select item 510190415.

Mechanism of tacrolimus-induced chronic renal fibrosis following transplantation is regulated by ox-LDL and its receptor, LOX-1

Shi Deng, Tao Jin, Li Zhang, Hong Bu, Peng Zhang

Mol Med Rep. 2016 Nov; 14(5): 4124–4134. Published online 2016 Sep 13. doi: 10.3892/mmr.2016.5735

PMCID:: PMC5101904

Abstract Article PDF–2.6M

Select item 509107816.

Regulation Of Coronary Endothelial Function By Interactions Between TNF-Alpha, LOX-1 And Adiponectin In Apolipoprotein E Knock Out Mice

Xiuping Chen, Hanrui Zhang, Michael A Hill, Cuihua Zhang, Yoonjung Park

J Vasc Res. Author manuscript; available in PMC 2017 Apr 7.

Published in final edited form as: J Vasc Res. 2015; 52(6): 372–382. Published online 2016 Apr 7. doi: 10.1159/000443887

PMCID:: PMC5091078

Abstract Article PDF–3.1M

Select item 488222517.

Enzymatically modified LDL promotes foam cell formation in smooth muscle cells via macropinocytosis and enhances receptor mediated uptake of oxidized LDL

Bijoy Chellan, Catherine A. Reardon, Godfrey S. Getz, Marion A. Hofmann Bowman

Arterioscler Thromb Vasc Biol. Author manuscript; available in PMC 2017 Jun 1.

Published in final edited form as: Arterioscler Thromb Vasc Biol. 2016 Jun; 36(6): 1101–1113. Published online 2016 Apr 14. doi: 10.1161/ATVBAHA.116.307306

PMCID:: PMC4882225

Abstract Article PDF–1.4M

Select item 487301818.

Deletion of LOX-1 Protects against Heart Failure Induced by Doxorubicin

Chiharu Yokoyama, Takuma Aoyama, Takahiro Ido, Akemi Kakino, Takeru Shiraki, Toshiki Tanaka, Kazuhiko Nishigaki, Aiko Hasegawa, Yoshiko Fujita, Tatsuya Sawamura, Shinya Minatoguchi

PLoS One. 2016; 11(5): e0154994. Published online 2016 May 19. doi: 10.1371/journal.pone.0154994

PMCID:: PMC4873018

Abstract Article PDF–8.3M

Select item 478684019.

Plasma L5 levels are elevated in ischemic stroke patients and enhance platelet aggregation

Ming-Yi Shen, Fang-Yu Chen, Jing-Fang Hsu, Ru-Huei Fu, Chia-Ming Chang, Chiz-Tzung Chang, Chung-Hsiang Liu, Jia-Rong Wu, An-Sheng Lee, Hua-Chen Chan, Joen-Rong Sheu, Shinn-Zong Lin, Woei-Cherng Shyu, Tatsuya Sawamura, Kuan-Cheng Chang, Chung Y. Hsu, Chu-Huang Chen

Blood. 2016 Mar 10; 127(10): 1336–1345. Prepublished online 2015 Dec 17. doi: 10.1182/blood-2015-05-646117

PMCID:: PMC4786840

Abstract Article

Select item 426773820.

LOX-1 Plays an Important Role in Ischemia-Induced Angiogenesis of Limbs

Takeru Shiraki, Takuma Aoyama, Chiharu Yokoyama, Yuka Hayakawa, Toshiki Tanaka, Kazuhiko Nishigaki, Tatsuya Sawamura, Shinya Minatoguchi

PLoS One. 2014; 9(12): e114542. Published online 2014 Dec 16. doi: 10.1371/journal.pone.0114542

PMCID:: PMC4267738

Abstract Article PDF–714K

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