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Select item 109176601.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 69088062.

Eosinophil-platelet interactions promote atherosclerosis and stabilize thrombosis with eosinophil extracellular traps

Charlotte Marx, Julia Novotny, Danby Salbeck, Katie R. Zellner, Leo Nicolai, Kami Pekayvaz, Badr Kilani, Sven Stockhausen, Niklas Bürgener, Danny Kupka, Thomas J. Stocker, Ludwig T. Weckbach, Joachim Pircher, Markus Moser, Michael Joner, Walter Desmet, Tom Adriaenssens, Franz-Josef Neumann, Anthony H. Gerschlick, Jurrien M. ten Berg, Michael Lorenz, Konstantin Stark

Blood. 2019 Nov 21; 134(21): 1859–1872. Prepublished online 2019 Sep 3. doi: 10.1182/blood.2019000518

PMCID:: PMC6908806

Abstract Article

Select item 68567283.

The Axonal Membrane Protein PRG2 Inhibits PTEN and Directs Growth to Branches

Annika Brosig, Joachim Fuchs, Fatih Ipek, Cristina Kroon, Sandra Schrötter, Mayur Vadhvani, Alexandra Polyzou, Julia Ledderose, Michiel van Diepen, Hermann-Georg Holzhütter, Thorsten Trimbuch, Niclas Gimber, Jan Schmoranzer, Ivo Lieberam, Christian Rosenmund, Christian Spahn, Patrick Scheerer, Michal Szczepek, George Leondaritis, Britta J. Eickholt

Cell Rep. 2019 Nov 12; 29(7): 2028–2040.e8. Published online 2019 Nov 12. doi: 10.1016/j.celrep.2019.10.039

PMCID:: PMC6856728

Abstract Article

Select item 63064574.

Identification of Piecemeal Degranulation and Vesicular Transport of MBP-1 in Liver-Infiltrating Mouse Eosinophils During Acute Experimental Schistosoma mansoni Infection

Felipe F. Dias, Kátia B. Amaral, Kássia K. Malta, Thiago P. Silva, Gabriel S. C. Rodrigues, Florence M. Rosa, Gisele O. L. Rodrigues, Vivian V. Costa, Hélio Chiarini-Garcia, Peter F. Weller, Rossana C. N. Melo

Front Immunol. 2018; 9: 3019. Published online 2018 Dec 20. doi: 10.3389/fimmu.2018.03019

PMCID:: PMC6306457

Abstract Article PDF–5.6M

Select item 55576405.

Frontline Science: Eosinophil-deficient MBP-1 and EPX double-knockout mice link pulmonary remodeling and airway dysfunction with type 2 inflammation

Sergei I. Ochkur, Alfred D. Doyle, Elizabeth A. Jacobsen, William E. LeSuer, Wen Li, Cheryl A. Protheroe, Katie R. Zellner, Dana Colbert, HuaHao H. Shen, Charlie G. Irvin, James J. Lee, Nancy A. Lee

J Leukoc Biol. 2017 Sep; 102(3): 589–599. Published online 2017 May 17. doi: 10.1189/jlb.3HI1116-488RR

PMCID:: PMC5557640

Abstract Article

Select item 53812266.

Fancd2 in vivo interaction network reveals a non-canonical role in mitochondrial function

Tingting Zhang, Wei Du, Andrew F. Wilson, Satoshi H. Namekawa, Paul R. Andreassen, Amom Ruhikanta Meetei, Qishen Pang

Sci Rep. 2017; 7: 45626. Published online 2017 Apr 5. doi: 10.1038/srep45626

PMCID:: PMC5381226

Abstract Article PDF–1.4M

Select item 52231597.

Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression

Alexandra Naba, Karl R. Clauser, D. R. Mani, Steven A. Carr, Richard O. Hynes

Sci Rep. 2017; 7: 40495. Published online 2017 Jan 10. doi: 10.1038/srep40495

PMCID:: PMC5223159

Abstract Article PDF–2.3M

Select item 50655288.

Precise Somatotopic Thalamocortical Axon Guidance Depends on LPA-Mediated PRG-2/Radixin Signaling

Jin Cheng, Sadhna Sahani, Torben Johann Hausrat, Jenq-Wei Yang, Haichao Ji, Nikolai Schmarowski, Heiko Endle, Xinfeng Liu, Yunbo Li, Rahel Böttche, Konstantin Radyushkin, Hans M. Maric, Anna Hoerder-Suabedissen, Zoltán Molnár, Pierre-Hugues Prouvot, Thorsten Trimbuch, Olaf Ninnemann, Jisen Huai, Wei Fan, Barbara Visentin, Roger Sabbadini, Kristian Strømgaard, Albrecht Stroh, Heiko J. Luhmann, Matthias Kneussel, Robert Nitsch, Johannes Vogt

Neuron. 2016 Oct 5; 92(1): 126–142. doi: 10.1016/j.neuron.2016.08.035

PMCID:: PMC5065528

Abstract Article

Select item 49702139.

Decreased expression levels of Ifi genes is associated to the increased resistance to spontaneous arthritis disease in mice deficiency of IL-1RA

Xiaoyun Liu, Yan Jiao, Yanhong Cao, Nan Deng, Yonghui Ma, Karen A. Hasty, Andrew Kang, Hong Chen, John M. Stuart, Weikuan Gu

BMC Immunol. 2016; 17: 25. Published online 2016 Aug 2. doi: 10.1186/s12865-016-0163-y

PMCID:: PMC4970213

Abstract Article PDF–2.5M

Select item 486034610.

Pulmonary neuroendocrine cells function as airway sensors to control lung immune response

Kelsey Branchfield, Leah Nantie, Jamie M. Verheyden, Pengfei Sui, Mark D. Wienhold, Xin Sun

Science. Author manuscript; available in PMC 2017 Feb 12.

Published in final edited form as: Science. 2016 Feb 12; 351(6274): 707–710. Published online 2016 Jan 7. doi: 10.1126/science.aad7969

PMCID:: PMC4860346

Abstract Article PDF–1.8M

Select item 457729711.

The transcription factor XBP1 is selectively required for eosinophil differentiation

Sarah E. Bettigole, Raphael Lis, Stanley Adoro, Ann-Hwee Lee, Lisa A. Spencer, Peter F. Weller, Laurie H. Glimcher

Nat Immunol. Author manuscript; available in PMC 2016 Feb 1.

Published in final edited form as: Nat Immunol. 2015 Aug; 16(8): 829–837. Published online 2015 Jul 6. doi: 10.1038/ni.3225

PMCID:: PMC4577297

Abstract Article PDF–2.1M

Select item 396495512.

The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data

Gautier Koscielny, Gagarine Yaikhom, Vivek Iyer, Terrence F. Meehan, Hugh Morgan, Julian Atienza-Herrero, Andrew Blake, Chao-Kung Chen, Richard Easty, Armida Di Fenza, Tanja Fiegel, Mark Grifiths, Alan Horne, Natasha A. Karp, Natalja Kurbatova, Jeremy C. Mason, Peter Matthews, Darren J. Oakley, Asfand Qazi, Jack Regnart, Ahmad Retha, Luis A. Santos, Duncan J. Sneddon, Jonathan Warren, Henrik Westerberg, Robert J. Wilson, David G. Melvin, Damian Smedley, Steve D. M. Brown, Paul Flicek, William C. Skarnes, Ann-Marie Mallon, Helen Parkinson

Nucleic Acids Res. 2014 Jan 1; 42(Database issue): D802–D809. Published online 2013 Nov 3. doi: 10.1093/nar/gkt977

PMCID:: PMC3964955

Abstract Article PDF–5.7M

Select item 395343413.

Eosinophils Are Important for Protection, Immunoregulation and Pathology during Infection with Nematode Microfilariae

Emma T. Cadman, Katherine A. Thysse, Siobhan Bearder, Anita Y. N. Cheung, Ashleigh C. Johnston, James J. Lee, Rachel A. Lawrence

PLoS Pathog. 2014 Mar; 10(3): e1003988. Published online 2014 Mar 13. doi: 10.1371/journal.ppat.1003988

PMCID:: PMC3953434

Abstract Article PDF–4.3M

Select item 373193214.

Expression of the secondary granule proteins major basic protein 1 (MBP-1) and eosinophil peroxidase (EPX) is required for eosinophilopoiesis in mice

Alfred D. Doyle, Elizabeth A. Jacobsen, Sergei I. Ochkur, Michael P. McGarry, Kevin G. Shim, David T. C. Nguyen, Cheryl Protheroe, Dana Colbert, Jake Kloeber, Joseph Neely, Kelly P. Shim, Kimberly D. Dyer, Helene F. Rosenberg, James J. Lee, Nancy A. Lee

Blood. 2013 Aug 1; 122(5): 781–790. Prepublished online 2013 Jun 4. doi: 10.1182/blood-2013-01-473405

PMCID:: PMC3731932

Abstract Article

Select item 324451615.

Eosinophils preserve parasitic nematode larvae by regulating local immunity

Nebiat G. Gebreselassie, Andrew R. Moorhead, Valeria Fabre, Lucille F. Gagliardo, Nancy A. Lee, James J. Lee, Judith A. Appleton

J Immunol. Author manuscript; available in PMC 2013 Jan 1.

Published in final edited form as: J Immunol. 2012 Jan 1; 188(1): 417–425. Published online 2011 Nov 30. doi: 10.4049/jimmunol.1101980

PMCID:: PMC3244516

Abstract Article PDF–1.2M

Select item 319198416.

Major Basic Protein from Eosinophils and Myeloperoxidase from Neutrophils Are Required for Protective Immunity to Strongyloides stercoralis in Mice

Amy E. O'Connell, Jessica A. Hess, Gilberto A. Santiago, Thomas J. Nolan, James B. Lok, James J. Lee, David Abraham

Infect Immun. 2011 Jul; 79(7): 2770–2778. doi: 10.1128/IAI.00931-10

PMCID:: PMC3191984

Abstract Article PDF–1.9M

Select item 302253417.

A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo

Graciana Diez-Roux, Sandro Banfi, Marc Sultan, Lars Geffers, Santosh Anand, David Rozado, Alon Magen, Elena Canidio, Massimiliano Pagani, Ivana Peluso, Nathalie Lin-Marq, Muriel Koch, Marchesa Bilio, Immacolata Cantiello, Roberta Verde, Cristian De Masi, Salvatore A. Bianchi, Juliette Cicchini, Elodie Perroud, Shprese Mehmeti, Emilie Dagand, Sabine Schrinner, Asja Nürnberger, Katja Schmidt, Katja Metz, Christina Zwingmann, Norbert Brieske, Cindy Springer, Ana Martinez Hernandez, Sarah Herzog, Frauke Grabbe, Cornelia Sieverding, Barbara Fischer, Kathrin Schrader, Maren Brockmeyer, Sarah Dettmer, Christin Helbig, Violaine Alunni, Marie-Annick Battaini, Carole Mura, Charlotte N. Henrichsen, Raquel Garcia-Lopez, Diego Echevarria, Eduardo Puelles, Elena Garcia-Calero, Stefan Kruse, Markus Uhr, Christine Kauck, Guangjie Feng, Nestor Milyaev, Chuang Kee Ong, Lalit Kumar, MeiSze Lam, Colin A. Semple, Attila Gyenesei, Stefan Mundlos, Uwe Radelof, Hans Lehrach, Paolo Sarmientos, Alexandre Reymond, Duncan R. Davidson, Pascal Dollé, Stylianos E. Antonarakis, Marie-Laure Yaspo, Salvador Martinez, Richard A. Baldock, Gregor Eichele, Andrea Ballabio

PLoS Biol. 2011 Jan; 9(1): e1000582. Published online 2011 Jan 18. doi: 10.1371/journal.pbio.1000582

PMCID:: PMC3022534

Abstract Article PDF–3.8M

Select item 257471718.

Major basic protein-1 promotes fibrosis of dystrophic muscle and attenuates the cellular immune response in muscular dystrophy

Michelle Wehling-Henricks, Sophie Sokolow, Jamie J. Lee, Kyu H. Myung, S. Armando Villalta, James G. Tidball

Hum Mol Genet. 2008 Aug 1; 17(15): 2280–2292. Published online 2008 Apr 21. doi: 10.1093/hmg/ddn129

PMCID:: PMC2574717

Abstract Article PDF–1.1M

Select item 159483019.

Lack of Eosinophil Peroxidase or Major Basic Protein Impairs Defense against Murine Filarial Infection

Sabine Specht, Michael Saeftel, Manuela Arndt, Elmar Endl, Bettina Dubben, Nancy A. Lee, James J. Lee, Achim Hoerauf

Infect Immun. 2006 Sep; 74(9): 5236–5243. doi: 10.1128/IAI.00329-06

PMCID:: PMC1594830

Abstract Article PDF–291K

Select item 130702720.

Eosinophils, but Not Eosinophil Peroxidase or Major Basic Protein, Are Important for Host Protection in Experimental Brugia pahangi Infection

Thirumalai Ramalingam, Patricia Porte, James Lee, T. V. Rajan

Infect Immun. 2005 Dec; 73(12): 8442–8443. doi: 10.1128/IAI.73.12.8442-8443.2005

PMCID:: PMC1307027

Abstract Article PDF–43K

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