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Items: 1 to 20 of 51

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
ADAP restraint of STAT1 signaling regulates macrophage phagocytosis in immune thrombocytopenia
Yiwei Xiong, Yanli Li, Xinxing Cui, Lifeng Zhang, Xiaodong Yang, Hebin Liu
Cell Mol Immunol. 2022 Aug; 19(8): 898–912. Published online 2022 May 30. doi: 10.1038/s41423-022-00881-2
PMCID:
PMC9149338
AbstractArticlePDF–4.7M
3.
Enhanced Susceptibility of ADAP-Deficient Mice to Listeria monocytogenes Infection Is Associated With an Altered Phagocyte Phenotype and Function
Martha A. L. Böning, Gerald P. Parzmair, Andreas Jeron, Henning P. Düsedau, Olivia Kershaw, Baolin Xu, Borna Relja, Dirk Schlüter, Ildiko Rita Dunay, Annegret Reinhold, Burkhart Schraven, Dunja Bruder
Front Immunol. 2021; 12: 724855. Published online 2021 Sep 30. doi: 10.3389/fimmu.2021.724855
PMCID:
PMC8515145
AbstractArticlePDF–21M
4.
BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING)
Kou Motani, Hidetaka Kosako
J Biol Chem. 2020 Aug 7; 295(32): 11174–11183. Published online 2020 Jun 17. doi: 10.1074/jbc.RA120.014323
PMCID:
PMC7415991
AbstractArticlePDF–2.0M
5.
ADAP Promotes Degranulation and Migration of NK Cells Primed During in vivo Listeria monocytogenes Infection in Mice
Martha A. L. Böning, Stephanie Trittel, Peggy Riese, Marco van Ham, Maxi Heyner, Martin Voss, Gerald P. Parzmair, Frank Klawonn, Andreas Jeron, Carlos A. Guzman, Lothar Jänsch, Burkhart Schraven, Annegret Reinhold, Dunja Bruder
Front Immunol. 2019; 10: 3144. Published online 2020 Jan 22. doi: 10.3389/fimmu.2019.03144
PMCID:
PMC6987423
AbstractArticlePDF–2.4M
6.
Quantitative interactomics in primary T cells unveils TCR signal diversification extent and dynamics
Guillaume Voisinne, Kristof Kersse, Karima Chaoui, Liaoxun Lu, Julie Chaix, Lichen Zhang, Marisa Goncalves Menoita, Laura Girard, Youcef Ounoughene, Hui Wang, Odile Burlet-Schiltz, Hervé Luche, Frédéric Fiore, Marie Malissen, Anne Gonzalez de Peredo, Yinming Liang, Romain Roncagalli, Bernard Malissen
Nat Immunol. Author manuscript; available in PMC 2020 Apr 7.
Published in final edited form as: Nat Immunol. 2019 Nov 1; 20(11): 1530–1541. Published online 2019 Oct 7. doi: 10.1038/s41590-019-0489-8
PMCID:
PMC6859066
AbstractArticlePDF–2.9M
7.
Immune Cell-Type Specific Ablation of Adapter Protein ADAP Differentially Modulates EAE
Jochen Rudolph, Clara Meinke, Martin Voss, Karina Guttek, Stefanie Kliche, Dirk Reinhold, Burkhart Schraven, Annegret Reinhold
Front Immunol. 2019; 10: 2343. Published online 2019 Oct 1. doi: 10.3389/fimmu.2019.02343
PMCID:
PMC6779796
AbstractArticlePDF–3.0M
8.
Characterization of Mice with a Platelet-Specific Deletion of the Adapter Molecule ADAP
Jochen Michael Rudolph, Karina Guttek, Gabriele Weitz, Clara Antonia Meinke, Stefanie Kliche, Dirk Reinhold, Burkhart Schraven, Annegret Reinhold
Mol Cell Biol. 2019 May 1; 39(9): e00365-18. Prepublished online 2019 Mar 4. Published online 2019 Apr 16. doi: 10.1128/MCB.00365-18
PMCID:
PMC6469923
AbstractArticlePDF–2.4M
9.
High-throughput discovery of novel developmental phenotypes
Mary E. Dickinson, Ann M. Flenniken, Xiao Ji, Lydia Teboul, Michael D. Wong, Jacqueline K. White, Terrence F. Meehan, Wolfgang J. Weninger, Henrik Westerberg, Hibret Adissu, Candice N. Baker, Lynette Bower, James M. Brown, L. Brianna Caddle, Francesco Chiani, Dave Clary, James Cleak, Mark J. Daly, James M. Denegre, Brendan Doe, Mary E. Dolan, Sarah M. Edie, Helmut Fuchs, Valerie Gailus-Durner, Antonella Galli, Alessia Gambadoro, Juan Gallegos, Shiying Guo, Neil R. Horner, Chih-wei Hsu, Sara J. Johnson, Sowmya Kalaga, Lance C. Keith, Louise Lanoue, Thomas N. Lawson, Monkol Lek, Manuel Mark, Susan Marschall, Jeremy Mason, Melissa L. McElwee, Susan Newbigging, Lauryl M.J. Nutter, Kevin A. Peterson, Ramiro Ramirez-Solis, Douglas J. Rowland, Edward Ryder, Kaitlin E. Samocha, John R. Seavitt, Mohammed Selloum, Zsombor Szoke-Kovacs, Masaru Tamura, Amanda G Trainor, Ilinca Tudose, Shigeharu Wakana, Jonathan Warren, Olivia Wendling, David B. West, Leeyean Wong, Atsushi Yoshiki, The International Mouse Phenotyping Consortium, Daniel G. MacArthur, Glauco P. Tocchini-Valentini, Xiang Gao, Paul Flicek, Allan Bradley, William C. Skarnes, Monica J. Justice, Helen E. Parkinson, Mark Moore, Sara Wells, Robert E. Braun, Karen L. Svenson, Martin Hrabe de Angelis, Yann Herault, Tim Mohun, Ann-Marie Mallon, R. Mark Henkelman, Steve D.M. Brown, David J. Adams, K.C. Kent Lloyd, Colin McKerlie, Arthur L. Beaudet, Maja Bucan, Stephen A. Murray
Nature. Author manuscript; available in PMC 2017 Mar 14.
Published in final edited form as: Nature. 2016 Sep 22; 537(7621): 508–514. Published online 2016 Sep 14. doi: 10.1038/nature19356
Correction in:
Nature. 2017 Nov 16; 551(7680): 398.
PMCID:
PMC5295821
AbstractArticlePDF–3.0M
10.
ADHESION AND DEGRANULATION PROMOTING ADAPTER PROTEIN (ADAP) PROMOTES CD8 T CELL DIFFERENTIATION AND RESIDENT MEMORY FORMATION AND FUNCTION DURING AN ACUTE INFECTION
Jessica K. Fiege, Lalit K. Beura, Brandon J. Burbach, Yoji Shimizu
J Immunol. Author manuscript; available in PMC 2017 Sep 15.
Published in final edited form as: J Immunol. 2016 Sep 15; 197(6): 2079–2089. Published online 2016 Aug 12. doi: 10.4049/jimmunol.1501805
PMCID:
PMC5010998
AbstractArticlePDF–1.2M
11.
Micro–adhesion rings surrounding TCR microclusters are essential for T cell activation
Akiko Hashimoto-Tane, Machie Sakuma, Hiroshi Ike, Tadashi Yokosuka, Yayoi Kimura, Osamu Ohara, Takashi Saito
J Exp Med. 2016 Jul 25; 213(8): 1609–1625. doi: 10.1084/jem.20151088
PMCID:
PMC4986522
AbstractArticlePDF–3.3M
12.
Activating Receptor Signals Drive Receptor Diversity in Developing Natural Killer Cells
Jacquelyn Freund, Rebecca M. May, Enjun Yang, Hongchuan Li, Matthew McCullen, Bin Zhang, Todd Lenvik, Frank Cichocki, Stephen K. Anderson, Taku Kambayashi
PLoS Biol. 2016 Aug; 14(8): e1002526. Published online 2016 Aug 8. doi: 10.1371/journal.pbio.1002526
Correction in:
PLoS Biol. 2016 Dec; 14(12): e1002590.
PMCID:
PMC4976927
AbstractArticlePDF–1.4M
13.
In Vivo Killing Capacity of Cytotoxic T Cells Is Limited and Involves Dynamic Interactions and T Cell Cooperativity
Stephan Halle, Kirsten Anja Keyser, Felix Rolf Stahl, Andreas Busche, Anja Marquardt, Xiang Zheng, Melanie Galla, Vigo Heissmeyer, Katrin Heller, Jasmin Boelter, Karen Wagner, Yvonne Bischoff, Rieke Martens, Asolina Braun, Kathrin Werth, Alexey Uvarovskii, Harald Kempf, Michael Meyer-Hermann, Ramon Arens, Melanie Kremer, Gerd Sutter, Martin Messerle, Reinhold Förster
Immunity. 2016 Feb 16; 44(2): 233–245. doi: 10.1016/j.immuni.2016.01.010
PMCID:
PMC4846978
AbstractArticle
14.
NEGATIVE REGULATION OF MEMORY PHENOTYPE CD8 T CELL CONVERSION BY ADHESION AND DEGRANULATION PROMOTING ADAPTER PROTEIN (ADAP)
Jessica K. Fiege, Brandon J. Burbach, Yoji Shimizu
J Immunol. Author manuscript; available in PMC 2016 Oct 1.
Published in final edited form as: J Immunol. 2015 Oct 1; 195(7): 3119–3128. Published online 2015 Aug 28. doi: 10.4049/jimmunol.1402670
PMCID:
PMC4575867
AbstractArticlePDF–874K
15.
ADAP and SKAP55 deficiency suppresses PD-1 expression in CD8+ cytotoxic T lymphocytes for enhanced anti-tumor immunotherapy
Chunyang Li, Weiyun Li, Jun Xiao, Shaozhuo Jiao, Fei Teng, Shengjie Xue, Chi Zhang, Chun Sheng, Qibin Leng, Christopher E Rudd, Bin Wei, Hongyan Wang
EMBO Mol Med. 2015 Jun; 7(6): 754–769. Published online 2015 Apr 7. doi: 10.15252/emmm.201404578
PMCID:
PMC4459816
AbstractArticlePDF–1.2M
16.
The Immune Adaptor ADAP Regulates Reciprocal TGF-β1-Integrin Crosstalk to Protect from Influenza Virus Infection
Chunyang Li, Shaozhuo Jiao, Guojun Wang, Yunzhen Gao, Chang Liu, Xijun He, Chi Zhang, Jun Xiao, Weiyun Li, Guoquan Zhang, Bin Wei, Hualan Chen, Hongyan Wang
PLoS Pathog. 2015 Apr; 11(4): e1004824. Published online 2015 Apr 24. doi: 10.1371/journal.ppat.1004824
PMCID:
PMC4409120
AbstractArticlePDF–3.9M
17.
Regulatory T cells require TCR signaling for their suppressive function
Amanda M. Schmidt, Wen Lu, Vishal J. Sindhava, Yanping Huang, Janis K. Burkhardt, Enjun Yang, Matthew J. Riese, Jonathan S. Maltzman, Martha S. Jordan, Taku Kambayashi
J Immunol. Author manuscript; available in PMC 2016 May 1.
Published in final edited form as: J Immunol. 2015 May 1; 194(9): 4362–4370. Published online 2015 Mar 27. doi: 10.4049/jimmunol.1402384
PMCID:
PMC4402269
AbstractArticlePDF–1.4M
18.
TCR and CD28 activate the transcription factor NF-κB in T-cells via distinct adaptor signaling complexes
Youg Raj Thaker, Helga Schneider, Christopher E. Rudd
Immunol Lett. 2015 Jan; 163(1): 113–119. doi: 10.1016/j.imlet.2014.10.020
PMCID:
PMC4286576
AbstractArticlePDF–1.4M
19.
Quantitative proteomic analysis of signalosome dynamics in primary T cells identifies the CD6 surface receptor as a Lat-independent TCR signaling hub
Romain Roncagalli, Simon Hauri, Fréderic Fiore, Yinming Liang, Zhi Chen, Amandine Sansoni, Kartiek Kanduri, Rachel Joly, Aurélie Malzac, Harri Lähdesmäki, Riitta Lahesmaa, Sho Yamasaki, Takashi Saito, Marie Malissen, Ruedi Aebersold, Matthias Gstaiger, Bernard Malissen
Nat Immunol. Author manuscript; available in PMC 2014 Oct 1.
Published in final edited form as: Nat Immunol. 2014 Apr; 15(4): 384–392. Published online 2014 Mar 2. doi: 10.1038/ni.2843
PMCID:
PMC4037560
AbstractArticlePDF–3.1M
20.
ADAP interactions with talin and kindlin promote platelet integrin αIIbβ3 activation and stable fibrinogen binding
Ana Kasirer-Friede, Jian Kang, Bryan Kahner, Feng Ye, Mark H. Ginsberg, Sanford J. Shattil
Blood. 2014 May 15; 123(20): 3156–3165. Prepublished online 2014 Feb 12. doi: 10.1182/blood-2013-08-520627
PMCID:
PMC4023421
AbstractArticle

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