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Items: 1 to 20 of 82

1.
A LTB4/CD11b self-amplifying loop drives pyogranuloma formation in chronic granulomatous disease
Kelsey C. Haist, Sophie L. Gibbings, Jordan Jacobelli, Kara J. Mould, Peter M. Henson, Donna L. Bratton
iScience. 2024 Apr 19; 27(4): 109589. Published online 2024 Mar 27. doi: 10.1016/j.isci.2024.109589
PMCID:
PMC11016758
AbstractArticlePDF–5.3M
2.
n-3 Polyunsaturated Fatty Acids Modulate LPS-Induced ARDS and the Lung–Brain Axis of Communication in Wild-Type versus Fat-1 Mice Genetically Modified for Leukotriene B4 Receptor 1 or Chemerin Receptor 23 Knockout
Jessica Hernandez, Julia Schäffer, Christiane Herden, Fabian Johannes Pflieger, Sylvia Reiche, Svenja Körber, Hiromu Kitagawa, Joelle Welter, Susanne Michels, Carsten Culmsee, Jens Bier, Natascha Sommer, Jing X. Kang, Konstantin Mayer, Matthias Hecker, Christoph Rummel
Int J Mol Sci. 2023 Sep; 24(17): 13524. Published online 2023 Aug 31. doi: 10.3390/ijms241713524
PMCID:
PMC10487657
AbstractArticlePDF–4.4M
3.
Intestinal epithelial BLT1 promotes mucosal repair
Shusaku Hayashi, Chithra K. Muraleedharan, Makito Oku, Sunil Tomar, Simon P. Hogan, Miguel Quiros, Charles A. Parkos, Asma Nusrat
JCI Insight. 2022 Dec 8; 7(23): e162392. Published online 2022 Dec 8. doi: 10.1172/jci.insight.162392
PMCID:
PMC9746898
AbstractArticlePDF–2.5M
4.
Constitutive activation of the NEAT1/miR-22-3p/Ltb4r1 signaling pathway in mice with myocardial injury following acute myocardial infarction
Lijie Wang, Lu Wang, Qi Wang
Aging (Albany NY) 2021 Jun 15; 13(11): 15307–15319. Published online 2021 Jun 3. doi: 10.18632/aging.203089
PMCID:
PMC8221362
AbstractArticlePDF–1.6M
5.
Expression of leukotriene B4 receptor 1 defines functionally distinct DCs that control allergic skin inflammation
Tomoaki Koga, Fumiyuki Sasaki, Kazuko Saeki, Soken Tsuchiya, Toshiaki Okuno, Mai Ohba, Takako Ichiki, Satoshi Iwamoto, Hirotsugu Uzawa, Keiko Kitajima, Chikara Meno, Eri Nakamura, Norihiro Tada, Yoshinori Fukui, Junichi Kikuta, Masaru Ishii, Yukihiko Sugimoto, Mitsuyoshi Nakao, Takehiko Yokomizo
Cell Mol Immunol. 2021 Jun; 18(6): 1437–1449. Published online 2020 Oct 9. doi: 10.1038/s41423-020-00559-7
PMCID:
PMC8167169
AbstractArticlePDF–3.8M
6.
Leukotriene B4 receptors contribute to house dust mite-induced eosinophilic airway inflammation via TH2 cytokine production
Donghwan Park, Dong-Wook Kwak, Jae-Hong Kim
BMB Rep. 2021 Mar 31; 54(3): 182–187. Published online 2021 Mar 31. doi: 10.5483/BMBRep.2021.54.3.247
PMCID:
PMC8016659
AbstractArticlePDF–7.5M
7.
Up-regulating microRNA-138-5p enhances the protective role of dexmedetomidine on myocardial ischemia-reperfusion injury mice via down-regulating Ltb4r1
Yanzi Chang, Lika Xing, Wenjuan Zhou, Wei Zhang
Cell Cycle. 2021; 20(4): 445–458. Published online 2021 Jan 28. doi: 10.1080/15384101.2021.1878330
PMCID:
PMC7894414
AbstractArticlePDF–2.4M
8.
Leukotriene B4 licenses inflammasome activation to enhance skin host defense
Ana Carolina Guerta Salina, Stephanie L. Brandt, Nathan Klopfenstein, Amondrea Blackman, Júlia Miranda Ribeiro Bazzano, Anderson Sá-Nunes, Nicole Byers-Glosson, Claudia Brodskyn, Natalia Machado Tavares, Icaro Bonyek Santos Da Silva, Alexandra I. Medeiros, C. Henrique Serezani
Proc Natl Acad Sci U S A. 2020 Dec 1; 117(48): 30619–30627. Published online 2020 Nov 12. doi: 10.1073/pnas.2002732117
PMCID:
PMC7720147
AbstractArticlePDF–1.2M
9.
The LTB4–BLT1 axis regulates actomyosin and β2-integrin dynamics during neutrophil extravasation
Bhagawat C. Subramanian, Nicolas Melis, Desu Chen, Weiye Wang, Devorah Gallardo, Roberto Weigert, Carole A. Parent
J Cell Biol. 2020 Oct 5; 219(10): e201910215. Published online 2020 Aug 26. doi: 10.1083/jcb.201910215
PMCID:
PMC7659729
AbstractArticlePDF–5.1M
10.
The PDK1-FoxO1 signaling in adipocytes controls systemic insulin sensitivity through the 5-lipoxygenase–leukotriene B4 axis
Tetsuya Hosooka, Yusei Hosokawa, Kaku Matsugi, Masakazu Shinohara, Yoko Senga, Yoshikazu Tamori, Chikako Aoki, Sho Matsui, Tsutomu Sasaki, Tadahiro Kitamura, Masashi Kuroda, Hiroshi Sakaue, Kazuhiro Nomura, Kei Yoshino, Yuko Nabatame, Yoshito Itoh, Kanji Yamaguchi, Yoshitake Hayashi, Jun Nakae, Domenico Accili, Takehiko Yokomizo, Susumu Seino, Masato Kasuga, Wataru Ogawa
Proc Natl Acad Sci U S A. 2020 May 26; 117(21): 11674–11684. Published online 2020 May 11. doi: 10.1073/pnas.1921015117
PMCID:
PMC7261087
AbstractArticlePDF–1.8M
11.
Expansion of Islet-Resident Macrophages Leads to Inflammation Affecting β Cell Proliferation and Function in Obesity
Wei Ying, Yun Sok Lee, Yi Dong, Jason S. Seidman, Meixiang Yang, Roi Isaac, Jong BaeSeo, Bi-Huei Yang, Joshua Wollam, Matthew Riopel, Joanne McNelis, Christopher K. Glass, Jerrold M. Olefsky, Wenxian Fu
Cell Metab. Author manuscript; available in PMC 2019 Aug 20.
Published in final edited form as: Cell Metab. 2019 Feb 5; 29(2): 457–474.e5. Published online 2018 Dec 27. doi: 10.1016/j.cmet.2018.12.003
PMCID:
PMC6701710
AbstractArticlePDF–1.6M
12.
Role of the high-affinity leukotriene B4 receptor signaling in fibrosis after unilateral ureteral obstruction in mice
Mariko Kamata, Hideki Amano, Yoshiya Ito, Tomoe Fujita, Fumisato Otaka, Kanako Hosono, Kouju Kamata, Yasuo Takeuchi, Takehiko Yokomizo, Takao Shimizu, Masataka Majima
PLoS One. 2019; 14(2): e0202842. Published online 2019 Feb 28. doi: 10.1371/journal.pone.0202842
Correction in:
PLoS One. 2019; 14(4): e0215625.
PMCID:
PMC6394974
AbstractArticlePDF–2.5M
13.
An extracellular matrix fragment drives epithelial remodeling and airway hyperresponsiveness
Dhiren F. Patel, Teresa Peiró, Amelia Shoemark, Samia Akthar, Simone A. Walker, Aleksander M. Grabiec, Patricia L. Jackson, Tracy Hussell, Amit Gaggar, Xin Xu, Jennifer L. Trevor, Jindong Li, Chad Steele, Gael Tavernier, J. Edwin Blalock, Robert M. Niven, Lisa G. Gregory, Angela Simpson, Clare M. Lloyd, Robert J. Snelgrove
Sci Transl Med. Author manuscript; available in PMC 2019 Jan 22.
Published in final edited form as: Sci Transl Med. 2018 Aug 22; 10(455): eaaq0693. doi: 10.1126/scitranslmed.aaq0693
PMCID:
PMC6342449
AbstractArticlePDF–2.0M
14.
BLT1 in dendritic cells promotes Th1/Th17 differentiation and its deficiency ameliorates TNBS-induced colitis
Jinfeng Zhou, Weiming Lai, Wanjie Yang, Juping Pan, Hu Shen, Yingying Cai, Cuixia Yang, Ningjia Ma, Yue Zhang, Ru Zhang, Xin Xie, Zhongjun Dong, Yuan Gao, Changsheng Du
Cell Mol Immunol. 2018 Dec; 15(12): 1047–1056. Published online 2018 Apr 18. doi: 10.1038/s41423-018-0030-2
PMCID:
PMC6269524
AbstractArticlePDF–2.0M
15.
Leukotriene B4 promotes neovascularization and macrophage recruitment in murine wet-type AMD models
Fumiyuki Sasaki, Tomoaki Koga, Mai Ohba, Kazuko Saeki, Toshiaki Okuno, Keijiro Ishikawa, Takahito Nakama, Shintaro Nakao, Shigeo Yoshida, Tatsuro Ishibashi, Hamid Ahmadieh, Mozhgan Rezaei Kanavi, Ali Hafezi-Moghadam, Josef M. Penninger, Koh-Hei Sonoda, Takehiko Yokomizo
JCI Insight. 2018 Sep 20; 3(18): e96902. Published online 2018 Sep 20. doi: 10.1172/jci.insight.96902
PMCID:
PMC6237215
AbstractArticlePDF–9.4M
16.
Excessive localized leukotriene B4 levels dictate poor skin host defense in diabetic mice
Stephanie L. Brandt, Sue Wang, Naiara N. Dejani, Nathan Klopfenstein, Seth Winfree, Luciano Filgueiras, Brian P. McCarthy, Paul R. Territo, C. Henrique Serezani
JCI Insight. 2018 Sep 6; 3(17): e120220. Published online 2018 Sep 6. doi: 10.1172/jci.insight.120220
PMCID:
PMC6171805
AbstractArticlePDF–4.6M
17.
BLTR1 in Monocytes Emerges as a Therapeutic Target For Vascular Inflammation With a Subsequent Intimal Hyperplasia in a Murine Wire-Injured Femoral Artery
Seung E. Baek, So Y. Park, Sun S. Bae, Koanhoi Kim, Won S. Lee, Chi D. Kim
Front Immunol. 2018; 9: 1938. Published online 2018 Aug 28. doi: 10.3389/fimmu.2018.01938
PMCID:
PMC6121004
AbstractArticlePDF–3.0M
18.
Macrophage-derived LTB4 promotes abscess formation and clearance of Staphylococcus aureus skin infection in mice
Stephanie L. Brandt, Nathan Klopfenstein, Soujuan Wang, Seth Winfree, Brian P. McCarthy, Paul R. Territo, Lloyd Miller, C. Henrique Serezani
PLoS Pathog. 2018 Aug; 14(8): e1007244. Published online 2018 Aug 13. doi: 10.1371/journal.ppat.1007244
PMCID:
PMC6107286
AbstractArticlePDF–24M
19.
Complement C5a Receptor is the Key Initiator of Neutrophil Adhesion Igniting Immune Complex-induced Arthritis
Yoshishige Miyabe, Chie Miyabe, Thomas T. Murooka, Edward Y. Kim, Gail A. Newton, Nancy D. Kim, Bodduluri Haribabu, Francis W. Luscinskas, Thorsten R. Mempel, Andrew D. Luster
Sci Immunol. Author manuscript; available in PMC 2017 May 18.
Published in final edited form as: Sci Immunol. 2017 Jan; 2(7): eaaj2195. Published online 2017 Jan 20. doi: 10.1126/sciimmunol.aaj2195
PMCID:
PMC5436313
AbstractArticlePDF–2.1M
20.
The leukotriene B4 receptors BLT1 and BLT2 form an antagonistic sensitizing system in peripheral sensory neurons
Sebastian Zinn, Marco Sisignano, Katharina Kern, Sandra Pierre, Sorin Tunaru, Holger Jordan, Jing Suo, Elsa-Marie Treutlein, Carlo Angioni, Nerea Ferreiros, Andreas Leffler, Natasja DeBruin, Stefan Offermanns, Gerd Geisslinger, Klaus Scholich
J Biol Chem. 2017 Apr 14; 292(15): 6123–6134. Published online 2017 Feb 27. doi: 10.1074/jbc.M116.769125
PMCID:
PMC5391745
AbstractArticlePDF–1.6M

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