PMC Links for GEO Profiles (Select 114165765) - PMC

Select item 53617371.

Potent and Selective KDM5 Inhibitor Stops Cellular Demethylation of H3K4me3 at Transcription Start Sites and Proliferation of MM1S Myeloma Cells

Anthony Tumber, Andrea Nuzzi, Edward S. Hookway, Stephanie B. Hatch, Srikannathasan Velupillai, Catrine Johansson, Akane Kawamura, Pavel Savitsky, Clarence Yapp, Aleksandra Szykowska, Na Wu, Chas Bountra, Claire Strain-Damerell, Nicola A. Burgess-Brown, Gian Filippo Ruda, Oleg Fedorov, Shonagh Munro, Katherine S. England, Radoslaw P. Nowak, Christopher J. Schofield, Nicholas B. La Thangue, Charlotte Pawlyn, Faith Davies, Gareth Morgan, Nick Athanasou, Susanne Müller, Udo Oppermann, Paul E. Brennan

Cell Chem Biol. 2017 Mar 16; 24(3): 371–380. Published online 2017 Mar 16. doi: 10.1016/j.chembiol.2017.02.006

PMCID:: PMC5361737

Abstract Article PDF–2.6M

Select item 44543712.

Multiple recurrent genetic events converge on control of histone lysine methylation in medulloblastoma

Paul A Northcott, Yukiko Nakahara, Xiaochong Wu, Lars Feuk, David W Ellison, Sid Croul, Stephen Mack, Paul N Kongkham, John Peacock, Adrian Dubuc, Young-Shin Ra, Karen Zilberberg, Jessica Mcleod, Stephen W Scherer, J Sunil Rao, Charles G Eberhart, Wiesia Grajkowska, Yancey Gillespie, Boleslaw Lach, Richard Grundy, Ian F Pollack, Ronald L Hamilton, Timothy Van Meter, Carlos G Carlotti, Frederick Boop, Darrell Bigner, Richard J Gilbertson, James T Rutka, Michael D Taylor

Nat Genet. Author manuscript; available in PMC 2015 Jun 3.

Published in final edited form as: Nat Genet. 2009 Apr; 41(4): 465–472. Published online 2009 Mar 8. doi: 10.1038/ng.336

PMCID:: PMC4454371

Abstract Article PDF–781K

Select item 39298863.

Jumonji domain-containing protein 2B silencing induces DNA damage response via STAT3 pathway in colorectal cancer

L Chen, L Fu, X Kong, J Xu, Z Wang, X Ma, Y Akiyama, Y Chen, J Fang

Br J Cancer. 2014 Feb 18; 110(4): 1014–1026. Published online 2014 Jan 28. doi: 10.1038/bjc.2013.808

PMCID:: PMC3929886

Abstract Article PDF–2.2M

Select item 38610584.

Histone Lysine Methylation Dynamics: Establishment, Regulation, and Biological Impact

Joshua C. Black, Capucine Van Rechem, Johnathan R. Whetstine

Mol Cell. Author manuscript; available in PMC 2013 Dec 12.

Published in final edited form as: Mol Cell. 2012 Nov 30; 48(4): 10.1016/j.molcel.2012.11.006. doi: 10.1016/j.molcel.2012.11.006

PMCID:: PMC3861058

Abstract Article PDF–2.1M

Select item 33088715.

Structural and Evolutionary Basis for the Dual Substrate Selectivity of Human KDM4 Histone Demethylase Family

Lars Hillringhaus, Wyatt W. Yue, Nathan R. Rose, Stanley S. Ng, Carina Gileadi, Christoph Loenarz, Simon H. Bello, James E. Bray, Christopher J. Schofield, Udo Oppermann

J Biol Chem. 2011 Dec 2; 286(48): 41616–41625. Published online 2011 Sep 13. doi: 10.1074/jbc.M111.283689

PMCID:: PMC3308871

Abstract Article PDF–2.6M

Select item 31780596.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 30608747.

Histone Demethylase JMJD2B Functions as a Co-Factor of Estrogen Receptor in Breast Cancer Proliferation and Mammary Gland Development

Masahito Kawazu, Kayoko Saso, Kit I. Tong, Tracy McQuire, Kouichiro Goto, Dong-Ok Son, Andrew Wakeham, Makoto Miyagishi, Tak W. Mak, Hitoshi Okada

PLoS One. 2011; 6(3): e17830. Published online 2011 Mar 18. doi: 10.1371/journal.pone.0017830

Correction in:: PLoS One. 2024; 19(5): e0303780.

PMCID:: PMC3060874

Abstract Article PDF–1.8M

Select item 26591978.

Dynamic Histone H1 Isotype 4 Methylation and Demethylation by Histone Lysine Methyltransferase G9a/KMT1C and the Jumonji Domain-containing JMJD2/KDM4 Proteins

Patrick Trojer, Jin Zhang, Masato Yonezawa, Andreas Schmidt, Haiyan Zheng, Thomas Jenuwein, Danny Reinberg

J Biol Chem. 2009 Mar 27; 284(13): 8395–8405. doi: 10.1074/jbc.M807818200

PMCID:: PMC2659197

Abstract Article PDF–797K

Select item 14824759.

Jmjd2b antagonizes H3K9 trimethylation at pericentric heterochromatin in mammalian cells

Barna D. Fodor, Stefan Kubicek, Masato Yonezawa, Roderick J. O’Sullivan, Roopsha Sengupta, Laura Perez-Burgos, Susanne Opravil, Karl Mechtler, Gunnar Schotta, Thomas Jenuwein

Genes Dev. 2006 Jun 15; 20(12): 1557–1562. doi: 10.1101/gad.388206

PMCID:: PMC1482475

Abstract Article PDF–406K

Select item 13924110.

Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences

Mammalian Gene Collection (MGC) Program Team

Proc Natl Acad Sci U S A. 2002 Dec 24; 99(26): 16899–16903. Published online 2002 Dec 11. doi: 10.1073/pnas.242603899

PMCID:: PMC139241

Abstract Article PDF–118K

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